Relationships between solid dispersion preparation process, particle size and drug release - An NMR and NMR microimaging study

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 2, 2010, Pages 311-319

  Dahlberg, Carina ^a,b   Millqvist Fureby, Anna ^b   Schuleit, Michael ^c   Furó, István ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b INSTITUTE FOR SURFACE CHEMISTRY   (Sweden)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Diffusion; Gel layer formation; HPMC; Hydroxypropyl methylcellulose; Rotoevaporation; Spray drying

Indexed keywords

PHENAZONE; POLYMER; WATER;

ARTICLE; DEUTERON NUCLEAR MAGNETIC RESONANCE; DRUG RELEASE; DRUG SOLUBILITY; EVAPORATION; GELATION; HYDRATION; PARTICLE SIZE; PROTON NUCLEAR MAGNETIC RESONANCE; ROTOEVAPORATION; SCANNING ELECTRON MICROSCOPY; SOLID; SPRAY DRYING; TABLET FORMULATION;

ANTIPYRINE; DIFFUSION; DRUG CARRIERS; KINETICS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; TABLETS; WATER;

EID: 77957281261     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.06.006     Document Type: Article

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