Effects of Kollicoat IR® and hydroxypropyl-β- cyclodextrin on the dissolution rate of omeprazole from its microparticles and enteric-coated capsules

Pharmaceutical Development and Technology

Volumn 15, Issue 5, 2010, Pages 500-510

  El Badry, Mahmoud ^a   Alanazi, Fars K ^a   Mahrous, Gamal M ^a   Alsarra, Ibrahim A ^a,b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Dissolution rate; Enteric coated capsules; Freeze drying; Hydroxypropyl cyclodextrin; Kollicoat IR ; Omeprazole; Spray drying

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BUFFER; COPOLYMER; EXCIPIENT; OMEPRAZOLE; POLYVINYL ALCOHOL; POLYVINYL ALCOHOL POLYETHYLENE GLYCOL GRAFT COPOLYMER; UNCLASSIFIED DRUG;

ARTICLE; COATED PARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CAPSULE; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG TRANSFORMATION; ENTERIC COATED TABLET; FREEZE DRYING; MELTING POINT; MICROPARTICLE ENZYME IMMUNOASSAY; MORPHOLOGY; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPE; SPRAY DRYING; TABLET PROPERTY; X RAY POWDER DIFFRACTION;

BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CAPSULES; DELAYED-ACTION PREPARATIONS; DENSITOMETRY; ENZYME INHIBITORS; EXCIPIENTS; FREEZE DRYING; KINETICS; MICROSCOPY, ELECTRON, SCANNING; OMEPRAZOLE; POLYVINYLS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 77956140494     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450903300171     Document Type: Article

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