Solubility, dissolution rate and bioavailability enhancement of irbesartan by solid dispersion technique

Chemical and Pharmaceutical Bulletin

Volumn 59, Issue 4, 2011, Pages 438-441

  Boghra, Rikisha Jaysukhbhai ^a   Kothawade, Pranita Chandrakant ^a   Belgamwar, Veena Shailendra ^a   Nerkar, Pankaj Padmakar ^a   Tekade, Avinash Ramrao ^a   Surana, Sanjay Javerilal ^a  

^a R C PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH   (India)

Author keywords

Bioavailability; Devitrification; Irbesartan; Solid dispersion; Solubility enhancement

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; IRBESARTAN;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; EXPERIMENTAL RABBIT; INFRARED SPECTROSCOPY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; TIME TO MAXIMUM PLASMA CONCENTRATION; VISCOSITY; X RAY DIFFRACTION;

ANIMALS; BIOLOGICAL AVAILABILITY; BIPHENYL COMPOUNDS; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLIZATION; RABBITS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TETRAZOLES; VISCOSITY; X-RAY DIFFRACTION;

EID: 79953663043     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.59.438     Document Type: Article

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