Novel valsartan-loaded solid dispersion with enhanced bioavailability and no crystalline changes

International Journal of Pharmaceutics

Volumn 422, Issue 1-2, 2012, Pages 202-210

  Yan, Yi Dong ^a   Sung, Jun Ho ^a   Kim, Kun Kook ^a   Kim, Dong Wuk ^b   Kim, Jong Oh ^a   Lee, Beom Jin ^c   Yong, Chul Soon ^a   Choi, Han Gon ^b  

^a Yeungnam University   (South Korea)

^b Hanyang University   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Enhanced bioavailability; Solid dispersion; Unchanged crystal; Valsartan

Indexed keywords

CRYSTALLIN; DODECYL SULFATE SODIUM; DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE; VALSARTAN; WATER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG RELEASE; DRUG SOLUBILITY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; X RAY DIFFRACTION;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DRUG CARRIERS; DRUG COMPOUNDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; POWDERS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM DODECYL SULFATE; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; TETRAZOLES; VALINE; WATER;

EID: 84655164813     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.10.053     Document Type: Article

References (23)

1. C. Brunella, D.M. Cleelia, I. Maria, and M. Agnese Improvement of solubility and stability of valsartan by hydroxypropyl-β-cyclodextrin J. Incl. Phenom. Macro. 54 2006 289 294
2. W.L. Chiou, and S. Riegelman Pharmaceutical application of solid dispersion systems J. Pharm. Sci. 60 1971 1281 1303
3. S. Chutimaworapan, G.C. Ritthidej, E. Yonemochi, T. Oguchi, and K. Yamamoto Effect of water-soluble carriers on dissolution characteristics of nifedipine solid dispersions Drug Dev. Ind. Pharm. 26 2000 1141 1150
4. D.Q.M. Craig The mechanism of drug release from solid dispersion in water-soluble polymers Int. J. Pharm. 231 2002 131 144 (Pubitemid 34033673)
5. J.B. Dressman, and C. Reppas In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs Eur. J. Pharm. Sci. S2 2000 S73 S80
6. J.H. Joe, W.M. Lee, Y.J. Park, K.H. Joe, D.H. Oh, Y.G. Seo, J.S. Woo, C.S. Yong, and H.G. Choi Effect of the solid-dispersion method on the solubility and crystalline property of tacrolimus Int. J. Pharm. 395 2010 161 166
7. K. Kachrimanis, I. Nikolakakis, and S. Malamataris Spherical crystal agglomeration of ibuprofen by the solvent-change technique in presence of methacrylic polymers J. Pharm. Sci. 89 2000 250 259 (Pubitemid 30120805)
8. H. Kaur, T.K.R. Das, R. Ajore, and L.M. Bharadwaj Covalent attachment of actin filaments to Tween 80 coated polystyrene beads for cargo transportation Biosystems 92 2008 69 75
9. C. Leuner, and J. Dressman Improving drug solubility for oral delivery using solid dispersions Eur. J. Pharm. Biopharm. 50 2000 47 60 (Pubitemid 30326688)
10. S.W. Lee, M.H. Kim, and C.K. Kim Encapsulation of ethanol by spray drying technique: effects of citric acid Int. J. Pharm. 187 1999 193 198
11. D.X. Li, Y.K. Oh, S.J. Lim, J.O. Kim, H.J. Yang, J.H. Sung, C.S. Yong, and H.G. Choi Novel gelatin microcapsule with bioavailability enhancement of ibuprofen using spray drying technique Int. J. Pharm. 355 2008 277 284
12. D.X. Li, Y.D. Yan, D.H. Oh, K.Y. Yang, Y.G. Seo, J.O. Kim, Y.I. Kim, C.S. Yong, and H.G. Choi Development of valsartan-loaded gelatin microcapsule without crystal change using hydroxypropylmethylcellulose as a stabilizer Drug Deliv. 17 2010 322 329
13. A. Markham, and K.L. Goa Valsartan. A review of its pharmacology and therapeutic use in essential hypertension Drugs 54 1997 299 311 (Pubitemid 27361837)
14. D.A. Miller, J.T. McConville, W. Yang, R.O. Williams, and J.W. McGinity Hot-melt extrusion for enhanced delivery of drug particles J. Pharm. Sci. 96 2007 361 376 (Pubitemid 46363567)
15. M. Newa, K.H. Bhandari, D.X. Li, J.O. Kim, D.S. Yoo, J.A. Kim, B.K. Yoo, J.S. Woo, W.S. Lyoo, C.S. Yong, and H.G. Choi Preparation and evaluation of immediate release ibuprofen solid dispersions using polyethylene glycol 4000 Biol. Pharm. Bull. 31 2008 939 945 (Pubitemid 351732002)
16. D.H. Oh, Y.J. Park, J.H. Kang, C.S. Yong, and H.G. Choi Physicochemical characterization and in vivo evaluation of flurbiprofen-loaded solid dispersion without crystalline change Drug Deliv. 18 2011 46 53
17. A.R. Shrivastava, B. Ursekar, and C.J. Kapadia Design, optimization, preparation and evaluation of dispersion granules of valsartan and formulation into tablets Curr. Drug Deliv. 6 2009 28 37
18. Society of Toxicology (SOT) Guiding Principles in the Use of Animals in Toxicology 2008 www.toxicology.org/AI/FA/guidingprinciples.pdf
19. L.S. Taylor, and G. Zografi Spectroscopic characterization interactions between PVP and indomethacin in amorphous molecular dispersions Pharm. Res. 14 1997 1691 1698 (Pubitemid 28062912)
20. V. Venkateswarlu, and K. Manjunath Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles J. Control. Release 95 2004 627 638 (Pubitemid 38344153)
21. S. Walser, R. Hruby, E. Hesse, H. Heinzl, and H. Mascher Preliminary toxicokinetic study with different crystal forms of S (+)-ibuprofen (dexibuprofen), and R, S-ibuprofen in rats Arzneimittelforschung 47 1997 750 754
22. M. Windbergs, C.J. Strachan, and P. Kleinebudde Understanding the solid-state behaviour of triglyceride solid lipid extrudates and its influence on dissolution Eur. J. Pharm. Biopharm. 71 2009 80 87
23. K. Yamashita, T. Nakate, K. Okimoto, A. Ohike, Y. Tokunaga, R. Ibuki, K. Higaki, and T. Kimura Establishment of new preparation method for solid dispersion formulation of tacrolimus Int. J. Pharm. 267 2003 79 91 (Pubitemid 37352952)