Can compression induce demixing in amorphous solid dispersions? A case study of naproxen-PVP K25

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 81, Issue 1, 2012, Pages 207-213

  Ayenew, Zelalem ^a   Paudel, Amrit ^a   Van Den Mooter, Guy ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Amorphous; Compression; FTIR; Glass transition; Plastic deformation; Solid dispersions

Indexed keywords

NAPROXEN; POVIDONE; PVP K25; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HYDROGEN BOND; MISCIBILITY; SEPARATION TECHNIQUE; TABLET COMPRESSION; THERMODYNAMICS;

DRUG CARRIERS; DRUG COMPOUNDING; HYDROGEN BONDING; NAPROXEN; POLYMERS; POVIDONE; PRESSURE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84861099396     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.01.007     Document Type: Article

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