Solid dispersions, Part I: Recent evolutions and future opportunities in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

Expert Opinion on Drug Delivery

Volumn 8, Issue 11, 2011, Pages 1501-1519

  Bikiaris, Dimitrios N ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Cyclodextrins complexation; Kneading; Poorly water soluble drugs; Solid dispersions; Solubility enhancement; Solvent evaporation; Spray drying; Wet milling

Indexed keywords

ACECLOFENAC; ALBENDAZOLE; APREPITANT; CARBAMAZEPINE; CARVEDILOL; CILOSTAZOL; CYCLOSPORIN A; DANAZOL; FENOFIBRATE; FUROSEMIDE; GLICLAZIDE; HESPERETIN; HYDROXYPROPYLMETHYLCELLULOSE; INDOMETACIN; ITRACONAZOLE; MACROGOL 6000; MEGESTROL; MEGESTROL ACETATE; MELOXICAM; NARINGENIN; NICARDIPINE; NORFLOXACIN; OMEPRAZOLE; RAPAMYCIN; SILICON DIOXIDE; SIMVASTATIN; SOLVENT; TELMISARTAN; TRANILAST; TRICOL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALACICLOVIR; VOCIFLON;

AREA UNDER THE CURVE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; EVAPORATION; HUMAN; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; REVIEW; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION; X RAY POWDER DIFFRACTION;

ANIMALS; BIOLOGICAL AVAILABILITY; BIOPHARMACEUTICS; CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; HUMANS; NANOSTRUCTURES; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; SOLUBILITY; SUSPENSIONS;

EID: 80054796578     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2011.618181     Document Type: Review

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