-
1
-
-
0038015262
-
Pharmacological effects of Cimicifuga racemosa
-
Borrelli F, Izzo A A., Ernst E. Pharmacological effects of Cimicifuga racemosa. Life Sci 2003 73 1215-1229
-
(2003)
Life Sci
, vol.73
, pp. 1215-1229
-
-
Borrelli, F.1
Izzo, A.A.2
Ernst, E.3
-
2
-
-
0012964325
-
A systematic review of the safety of black cohosh
-
Huntley A, Ernst E. A systematic review of the safety of black cohosh. Menopause 2003 10 58-64
-
(2003)
Menopause
, vol.10
, pp. 58-64
-
-
Huntley, A.1
Ernst, E.2
-
3
-
-
77449105279
-
Efficacy of black cohosh-containing preparations on menopausal symptoms: A meta analysis
-
Shams T, Setia M S., Hemmings R, McCusker J, Sewitch M, Ciampi A. Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta analysis. Altern Health Med 2010 16 36-44
-
(2010)
Altern Health Med
, vol.16
, pp. 36-44
-
-
Shams, T.1
Setia, M.S.2
Hemmings, R.3
McCusker, J.4
Sewitch, M.5
Ciampi, A.6
-
5
-
-
33749432298
-
Cimicifugae rhizoma: From origins, bioactive constituents to clinical outcomes
-
Li J X., Yu Z Y. Cimicifugae rhizoma: from origins, bioactive constituents to clinical outcomes. Curr Med Chem 2006 13 2927-2951
-
(2006)
Curr Med Chem
, vol.13
, pp. 2927-2951
-
-
Li, J.X.1
Yu, Z.Y.2
-
6
-
-
75749103266
-
Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh
-
van Breeman R B., Liang W, Banuvar S, Shulman L P., Pang Y, Tao Y, Nikolic D, Krock K M., Fabricant D S., Chen S-N, Hedayat S, Bolton J L., Pauli G F., Piersen C E., Krause E C., Geller S E., Farnsworth N R. Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh. Clin Pharmacol Ther 2010 87 219-225
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 219-225
-
-
Van Breeman, R.B.1
Liang, W.2
Banuvar, S.3
Shulman, L.P.4
Pang, Y.5
Tao, Y.6
Nikolic, D.7
Krock, K.M.8
Fabricant, D.S.9
Chen, S.-N.10
Hedayat, S.11
Bolton, J.L.12
Pauli, G.F.13
Piersen, C.E.14
Krause, E.C.15
Geller, S.E.16
Farnsworth, N.R.17
-
7
-
-
25844513840
-
Isolation of CYP3A4 inhibitors from the black cohosh (Cimicifuga racemosa)
-
Tsukamoto S, Aburatani M, Ohta T. Isolation of CYP3A4 inhibitors from the black cohosh (Cimicifuga racemosa). eCAM 2005 2 223-226
-
(2005)
ECAM
, vol.2
, pp. 223-226
-
-
Tsukamoto, S.1
Aburatani, M.2
Ohta, T.3
-
8
-
-
77950813145
-
Fukinolic acid derivatives and triterpene glycosides from black cohosh inhibit CYP isozymes, but are not cytotoxic to Hep-G2 cells in vitro
-
Huang Y, Jiang B, Nuntanakorn P, Kennelly E J., Shord S, Lawal T O., Soni K K., Mahady G B. Fukinolic acid derivatives and triterpene glycosides from black cohosh inhibit CYP isozymes, but are not cytotoxic to Hep-G2 cells in vitro. Curr Drug Saf 2010 5 118-124
-
(2010)
Curr Drug Saf
, vol.5
, pp. 118-124
-
-
Huang, Y.1
Jiang, B.2
Nuntanakorn, P.3
Kennelly, E.J.4
Shord, S.5
Lawal, T.O.6
Soni, K.K.7
Mahady, G.B.8
-
9
-
-
33744503982
-
Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry
-
Jiang B, Kronenberg F, Nuntanakorn P, Qiu M-H, Kennelly E J. Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry. J Agric Food Chem 2006 54 3242-3253
-
(2006)
J Agric Food Chem
, vol.54
, pp. 3242-3253
-
-
Jiang, B.1
Kronenberg, F.2
Nuntanakorn, P.3
Qiu, M.-H.4
Kennelly, E.J.5
-
10
-
-
77949457681
-
Rapid screening of commercially available herbal products for the inhibition of major human hepatic cytochrome P450 enzymes using the N-in-one cocktail
-
Sevior D K., Hokkanen J, Tolonen A, Abass K, Tursas L, Pelkonen O, Ahokas J T. Rapid screening of commercially available herbal products for the inhibition of major human hepatic cytochrome P450 enzymes using the N-in-one cocktail. Xenobiotica 2010 40 245-254
-
(2010)
Xenobiotica
, vol.40
, pp. 245-254
-
-
Sevior, D.K.1
Hokkanen, J.2
Tolonen, A.3
Abass, K.4
Tursas, L.5
Pelkonen, O.6
Ahokas, J.T.7
-
11
-
-
30044432615
-
Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans
-
Gurley B J., Barone G W., Williams D K., Carrier J, Breen P, Yates C R., Song P, Hubbard M A., Tong Y, Cheboyina S. Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans. Drug Metab Dispos 2006 34 69-74
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 69-74
-
-
Gurley, B.J.1
Barone, G.W.2
Williams, D.K.3
Carrier, J.4
Breen, P.5
Yates, C.R.6
Song, P.7
Hubbard, M.A.8
Tong, Y.9
Cheboyina, S.10
-
12
-
-
31444435037
-
Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: Comparison of a milk thistle and black cohosh product to rifampin and clarithromycin
-
Gurley B, Hubbard M A., Williams D K., Thaden J, Tong Y, Gentry W B., Breen P, Carrier D J., Cheboyina S. Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: comparison of a milk thistle and black cohosh product to rifampin and clarithromycin. J Clin Pharmacol 2006 46 201-213
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 201-213
-
-
Gurley, B.1
Hubbard, M.A.2
Williams, D.K.3
Thaden, J.4
Tong, Y.5
Gentry, W.B.6
Breen, P.7
Carrier, D.J.8
Cheboyina, S.9
-
13
-
-
19144363905
-
In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes
-
Gurley B J., Gardner S F., Hubbard M A., Williams D K., Gentry W B., Khan I A., Shah A. In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes. Clin Pharmacol Ther 2005 77 415-426
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 415-426
-
-
Gurley, B.J.1
Gardner, S.F.2
Hubbard, M.A.3
Williams, D.K.4
Gentry, W.B.5
Khan, I.A.6
Shah, A.7
-
14
-
-
33645100643
-
Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B
-
Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006 34 577-582
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 577-582
-
-
Fuchikami, H.1
Satoh, H.2
Tsujimoto, M.3
Ohdo, S.4
Ohtani, H.5
Sawada, Y.6
-
15
-
-
29644437496
-
An evidence-based systematic review of Echinacea (E. angustifolia DC, E. pallida, E. purpurea) by the Natural Standard Research Collaboration
-
Basch E, Ulbricht C, Basch S, Dalton S, Ernst E, Foppa I, Szapary P, Tiffany N, Orlando C W., Vora M. An evidence-based systematic review of Echinacea (E. angustifolia DC, E. pallida, E. purpurea) by the Natural Standard Research Collaboration. J Herb Pharmacother 2005 5 57-88
-
(2005)
J Herb Pharmacother
, vol.5
, pp. 57-88
-
-
Basch, E.1
Ulbricht, C.2
Basch, S.3
Dalton, S.4
Ernst, E.5
Foppa, I.6
Szapary, P.7
Tiffany, N.8
Orlando, C.W.9
Vora, M.10
-
16
-
-
22844438903
-
Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): A review of their chemistry, pharmacology and clinical properties
-
Barnes J, Anderson L A., Gibbons S, Phillipson J D. Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties. J Pharm Pharmacol 2005 57 929-954
-
(2005)
J Pharm Pharmacol
, vol.57
, pp. 929-954
-
-
Barnes, J.1
Anderson, L.A.2
Gibbons, S.3
Phillipson, J.D.4
-
17
-
-
33646200102
-
Echinacea in the prevention of induced rhinovirus colds: A meta analysis
-
Schoop R, Klein P, Suter A, Johnston S L. Echinacea in the prevention of induced rhinovirus colds: a meta analysis. Clin Ther 2006 28 174-183
-
(2006)
Clin Ther
, vol.28
, pp. 174-183
-
-
Schoop, R.1
Klein, P.2
Suter, A.3
Johnston, S.L.4
-
18
-
-
34250758071
-
Evaluation of Echinacea for the prevention and treatment of the common cold: A meta analysis
-
Shah S A., Sander S, White C M., Rinaldi M, Coleman C I. Evaluation of Echinacea for the prevention and treatment of the common cold: a meta analysis. Lancet Infect Dis 2007 7 473-480
-
(2007)
Lancet Infect Dis
, vol.7
, pp. 473-480
-
-
Shah, S.A.1
Sander, S.2
White, C.M.3
Rinaldi, M.4
Coleman, C.I.5
-
20
-
-
84890303772
-
-
In: Crozier A. Clifford M. N. Ashihara H. editors Plant secondary metabolites: occurrence, structure and role in the human diet Oxford Blackwell
-
Christensen L P., Brandt K. Acetylenes and psoralens. In: Crozier A Clifford M N. Ashihara H editors Plant secondary metabolites: occurrence, structure and role in the human diet. Oxford Blackwell 2006 137-173
-
(2006)
Acetylenes and Psoralens
, pp. 137-173
-
-
Christensen, L.P.1
Brandt, K.2
-
21
-
-
0037463827
-
Echinacea and truth in labeling
-
Gilroy C M., Steiner J F., Byers T, Shapiro H, Georgian W. Echinacea and truth in labeling. Arch Intern Med 2003 163 699-704
-
(2003)
Arch Intern Med
, vol.163
, pp. 699-704
-
-
Gilroy, C.M.1
Steiner, J.F.2
Byers, T.3
Shapiro, H.4
Georgian, W.5
-
22
-
-
0036273793
-
Transport of alkamides from Echinacea species through Caco-2 monolayers
-
Jager H, Meinel L, Dietz B, Lapke C, Bauer R, Merkle H P., Heilmann J. Transport of alkamides from Echinacea species through Caco-2 monolayers. Planta Med 2002 68 469-471
-
(2002)
Planta Med
, vol.68
, pp. 469-471
-
-
Jager, H.1
Meinel, L.2
Dietz, B.3
Lapke, C.4
Bauer, R.5
Merkle, H.P.6
Heilmann, J.7
-
23
-
-
1342310140
-
Matthias A, Blanchfield JT, Penman KG, Toth I, Lang C-S, de Voss JJ, Lehmann RP. Permeability studies of alkylamides and caffeic acid conjugates from Echinacea using a Caco-2 cell monolayer model
-
Matthias A, Blanchfield JT, Penman KG, Toth I, Lang C-S, De Voss JJ, Lehmann RP. Permeability studies of alkylamides and caffeic acid conjugates from Echinacea using a Caco-2 cell monolayer model. J Clin Pharm Ther 2004 29 7-13
-
(2004)
J Clin Pharm Ther
, vol.29
, pp. 7-13
-
-
-
24
-
-
0035671973
-
Absorption of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides after oral application of Echinacea purpurea tincture
-
Dietz B, Heilmann J, Bauer R. Absorption of dodeca-2E,4E,8Z,10E/Z- tetraenoic acid isobutylamides after oral application of Echinacea purpurea tincture. Planta Med 2001 67 863-864
-
(2001)
Planta Med
, vol.67
, pp. 863-864
-
-
Dietz, B.1
Heilmann, J.2
Bauer, R.3
-
25
-
-
18844370636
-
Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans
-
Woelkart K, Koidl C, Grisold A, Gangemi JD, Turner RB, Marth E, Bauer R. Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans. J Clin Pharmacol 2005 45 683-689
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 683-689
-
-
Woelkart, K.1
Koidl, C.2
Grisold, A.3
Gangemi, J.D.4
Turner, R.B.5
Marth, E.6
Bauer, R.7
-
26
-
-
23144449794
-
Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion
-
Matthias A, Addison R S., Penman K G., Dickinson R G., Bone K M., Lehmann R P. Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion. Life Sci 2005 77 2018-2029
-
(2005)
Life Sci
, vol.77
, pp. 2018-2029
-
-
Matthias, A.1
Addison, R.S.2
Penman, K.G.3
Dickinson, R.G.4
Bone, K.M.5
Lehmann, R.P.6
-
27
-
-
20644447802
-
Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes
-
Matthias A, Gillam E M. J., Penman K G., Matovic N J., Bone K M., De Voss J J., Lehmann R P. Cytochrome P450 enzyme-mediated degradation of Echinacea alkylamides in human liver microsomes. Chem Biol Interact 2005 155 62-70
-
(2005)
Chem Biol Interact
, vol.155
, pp. 62-70
-
-
Matthias, A.1
Gillam, E.M.J.2
Penman, K.G.3
Matovic, N.J.4
Bone, K.M.5
De Voss, J.J.6
Lehmann, R.P.7
-
28
-
-
77955597356
-
Metabolism of the major Echinacea alkylamide N -isobutyldodeca-2E,4E,8Z, 10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes
-
Toselli F, Matthias A, Bone K M., Gillam E M. J., Lehmann R P. Metabolism of the major Echinacea alkylamide N -isobutyldodeca-2E,4E,8Z,10Z-tetraenamide by human recombinant cytochrome P450 enzymes and human liver microsomes. Phytother Res 2010 24 1195-1201
-
(2010)
Phytother Res
, vol.24
, pp. 1195-1201
-
-
Toselli, F.1
Matthias, A.2
Bone, K.M.3
Gillam, E.M.J.4
Lehmann, R.P.5
-
29
-
-
67449131895
-
Echinacea metabolism and drug interactions: The case for standardization of a complementary medicine
-
Toselli F, Matthias A, Gillam E M. J. Echinacea metabolism and drug interactions: the case for standardization of a complementary medicine. Life Sci 2009 85 97-106
-
(2009)
Life Sci
, vol.85
, pp. 97-106
-
-
Toselli, F.1
Matthias, A.2
Gillam, E.M.J.3
-
30
-
-
0033868271
-
An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures
-
Budzinski J W., Foster B C., Vandenhoek S, Arnason J T. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000 7 273-282
-
(2000)
Phytomedicine
, vol.7
, pp. 273-282
-
-
Budzinski, J.W.1
Foster, B.C.2
Vandenhoek, S.3
Arnason, J.T.4
-
31
-
-
0037911509
-
In vitro inhibition of human cytochrome P450-mediated metabolism of marker substrates by natural products
-
Foster B C., Vandenhoek S, Hana J, Krantis A, Akhtar M H., Bryan M, Budzinski J W., Ramputh A, Arnason J T. In vitro inhibition of human cytochrome P450-mediated metabolism of marker substrates by natural products. Phytomedicine 2003 10 334-342
-
(2003)
Phytomedicine
, vol.10
, pp. 334-342
-
-
Foster, B.C.1
Vandenhoek, S.2
Hana, J.3
Krantis, A.4
Akhtar, M.H.5
Bryan, M.6
Budzinski, J.W.7
Ramputh, A.8
Arnason, J.T.9
-
32
-
-
1542348613
-
An approach to the in vitro evaluation of potential for cytochrome P450 enzyme inhibition from herbals and other natural remedies
-
Strandell J, Neil A, Carlin G. An approach to the in vitro evaluation of potential for cytochrome P450 enzyme inhibition from herbals and other natural remedies. Phytomedicine 2004 11 98-104
-
(2004)
Phytomedicine
, vol.11
, pp. 98-104
-
-
Strandell, J.1
Neil, A.2
Carlin, G.3
-
33
-
-
22244480328
-
Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9
-
Yale S H., Glurich I. Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. J Altern Complement Med 2005 11 433-439
-
(2005)
J Altern Complement Med
, vol.11
, pp. 433-439
-
-
Yale, S.H.1
Glurich, I.2
-
34
-
-
35348969727
-
Effects of herbal products and their constituents on human cytochrome P450(2E1) activity
-
Raner G M., Cornelious S, Moulick K, Wang Y, Mortensen A, Cech N B. Effects of herbal products and their constituents on human cytochrome P450(2E1) activity. Food Chem Toxicol 2007 45 2359-2365
-
(2007)
Food Chem Toxicol
, vol.45
, pp. 2359-2365
-
-
Raner, G.M.1
Cornelious, S.2
Moulick, K.3
Wang, Y.4
Mortensen, A.5
Cech, N.B.6
-
35
-
-
34848906016
-
The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol
-
Hellum B H., Nilsen O G. The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol. Basic Clin Pharmacol Toxicol 2007 101 350-358
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.101
, pp. 350-358
-
-
Hellum, B.H.1
Nilsen, O.G.2
-
36
-
-
36549007414
-
Modulation of human cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in Caco-2 cell monolayers by selected commercial-source milk thistle and goldenseal products
-
Budzinski J W., Trudeau V L., Drouin C E., Panahi M, Arnason J T., Foster B C. Modulation of human cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in Caco-2 cell monolayers by selected commercial-source milk thistle and goldenseal products. Can J Physiol Pharmacol 2007 85 966-978
-
(2007)
Can J Physiol Pharmacol
, vol.85
, pp. 966-978
-
-
Budzinski, J.W.1
Trudeau, V.L.2
Drouin, C.E.3
Panahi, M.4
Arnason, J.T.5
Foster, B.C.6
-
37
-
-
38849196790
-
The interaction of selected phytochemicals, HIV drugs, and commercial-source herbal teas and capsules with human cytochrome P450 3A4 and P-glycoprotein
-
Budzinski J W., Foster B C., Trudeau V L., Drouin C E., Bafi-Yeboa N, Arnason J T. The interaction of selected phytochemicals, HIV drugs, and commercial-source herbal teas and capsules with human cytochrome P450 3A4 and P-glycoprotein. Pharm Biol 2008 46 53-65
-
(2008)
Pharm Biol
, vol.46
, pp. 53-65
-
-
Budzinski, J.W.1
Foster, B.C.2
Trudeau, V.L.3
Drouin, C.E.4
Bafi-Yeboa, N.5
Arnason, J.T.6
-
38
-
-
42149119034
-
In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products
-
Hellum B H., Nilsen O G. In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products. Basic Clin Pharmacol Toxicol 2008 102 466-475
-
(2008)
Basic Clin Pharmacol Toxicol
, vol.102
, pp. 466-475
-
-
Hellum, B.H.1
Nilsen, O.G.2
-
39
-
-
34250156690
-
Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content
-
Modarai M, Gertsch J, Suter A, Heinrich M, Kortenkamp A. Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content. J Pharm Pharmacol 2007 59 567-573
-
(2007)
J Pharm Pharmacol
, vol.59
, pp. 567-573
-
-
Modarai, M.1
Gertsch, J.2
Suter, A.3
Heinrich, M.4
Kortenkamp, A.5
-
40
-
-
53949122693
-
In vitro CYP3A4 metabolism: Inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition
-
Hansen T S., Nilsen O G. In vitro CYP3A4 metabolism: inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition. Basic Clin Pharmacol Toxicol 2008 103 445-449
-
(2008)
Basic Clin Pharmacol Toxicol
, vol.103
, pp. 445-449
-
-
Hansen, T.S.1
Nilsen, O.G.2
-
41
-
-
79955088016
-
Safety of herbal medicinal products: Echinacea and selected alkylamides do not induce CYP3A4 mRNA expression
-
Article ID 213021, 7 pages
-
Modarai M, Silva E, Suter A, Herinrich M, Kortenkamp A. Safety of herbal medicinal products: Echinacea and selected alkylamides do not induce CYP3A4 mRNA expression. Evid Based Complement Alternat Med 2011 Article ID 213021, 7 pages
-
(2011)
Evid Based Complement Alternat Med
-
-
Modarai, M.1
Silva, E.2
Suter, A.3
Herinrich, M.4
Kortenkamp, A.5
-
42
-
-
77749308316
-
Metabolomic profiling of liquid Echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4)
-
Modarai M, Yang M, Suter A, Kortenkamp A, Heinrich M. Metabolomic profiling of liquid Echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4). Planta Med 2010 76 378-385
-
(2010)
Planta Med
, vol.76
, pp. 378-385
-
-
Modarai, M.1
Yang, M.2
Suter, A.3
Kortenkamp, A.4
Heinrich, M.5
-
43
-
-
41349089916
-
P-glycoprotein inhibitory activity of lipophilic constituents of Echinacea pallida roots in a human proximal cell line
-
Romiti N, Pellati F, Nieri P, Benvenuti S, Adinolfi B, Chieli E. P-glycoprotein inhibitory activity of lipophilic constituents of Echinacea pallida roots in a human proximal cell line. Planta Med 2008 74 264-266
-
(2008)
Planta Med
, vol.74
, pp. 264-266
-
-
Romiti, N.1
Pellati, F.2
Nieri, P.3
Benvenuti, S.4
Adinolfi, B.5
Chieli, E.6
-
44
-
-
58149485468
-
Echinacea purpurea and P-glycoprotein drug transport in Caco-2 cells
-
Hansen T S., Nilsen O G. Echinacea purpurea and P-glycoprotein drug transport in Caco-2 cells. Phytother Res 2009 23 86-91
-
(2009)
Phytother Res
, vol.23
, pp. 86-91
-
-
Hansen, T.S.1
Nilsen, O.G.2
-
45
-
-
78049323193
-
The effect of standardized Echinacea purpurea extract on rat cytochrome P450 expression level
-
Mrozikiewicz P M., Bogacz A, Karasiewicz M, Mikolajczak P L., Ozarowski M, Seremak-Mrozikiewicz A, Czerny B, Bobkiewicz-Kozlowska T, Grzeskowiak E. The effect of standardized Echinacea purpurea extract on rat cytochrome P450 expression level. Phytomedicine 2010 17 830-833
-
(2010)
Phytomedicine
, vol.17
, pp. 830-833
-
-
Mrozikiewicz, P.M.1
Bogacz, A.2
Karasiewicz, M.3
Mikolajczak, P.L.4
Ozarowski, M.5
Seremak-Mrozikiewicz, A.6
Czerny, B.7
Bobkiewicz-Kozlowska, T.8
Grzeskowiak, E.9
-
46
-
-
1642441388
-
The effect of echinacea (Echinacea purpurea) on cytochrome P450 activity in vivo
-
Gorski J C., Huang S M., Mitchell A P., Hamman A, Hilligoss J K., Zaheer N A., Desai M, Miller M, Hall S D. The effect of echinacea (Echinacea purpurea) on cytochrome P450 activity in vivo. Clin Pharmacol Ther 2004 75 89-100
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 89-100
-
-
Gorski, J.C.1
Huang, S.M.2
Mitchell, A.P.3
Hamman, A.4
Hilligoss, J.K.5
Zaheer, N.A.6
Desai, M.7
Miller, M.8
Hall, S.D.9
-
47
-
-
0031696409
-
The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin
-
Gorski J C., Jones D R., Haehner-Daniels B D., Hamman M A., O'Mara E M., Hall S D. The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin. Clin Pharmacol Ther 1998 64 133-143
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 133-143
-
-
Gorski, J.C.1
Jones, D.R.2
Haehner-Daniels, B.D.3
Hamman, M.A.4
O'Mara, E.M.5
Hall, S.D.6
-
48
-
-
0042833213
-
The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity
-
Gorski J C., Vannaprasaht S, Hamman M A., Ambrosius W T., Bruce M A., Haehner-Daniels B, Hall S D. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity. Clin Pharmacol Ther 2003 74 275-287
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 275-287
-
-
Gorski, J.C.1
Vannaprasaht, S.2
Hamman, M.A.3
Ambrosius, W.T.4
Bruce, M.A.5
Haehner-Daniels, B.6
Hall, S.D.7
-
49
-
-
53249123498
-
Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: Effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea
-
Gurley B J., Swain A, Hubbard M A., Williams D K., Barone G, Hartsfield F, Tong Y, Carrier D J., Cheboyina S, Battu S K. Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea. Mol Nutr Food Res 2008 52 755-763
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 755-763
-
-
Gurley, B.J.1
Swain, A.2
Hubbard, M.A.3
Williams, D.K.4
Barone, G.5
Hartsfield, F.6
Tong, Y.7
Carrier, D.J.8
Cheboyina, S.9
Battu, S.K.10
-
50
-
-
7944225802
-
In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto
-
Gurley B J., Gardner S F., Hubbard M A., Williams D K., Gentry W B., Carrier J, Khan I A., Edwards D J., Shah A. In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto. Clin Pharmacol Ther 2004 76 428-440
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 428-440
-
-
Gurley, B.J.1
Gardner, S.F.2
Hubbard, M.A.3
Williams, D.K.4
Gentry, W.B.5
Carrier, J.6
Khan, I.A.7
Edwards, D.J.8
Shah, A.9
-
51
-
-
77955436236
-
Echinacea purpurea significantly induces cytochrome P450 3A activity but does not alter lopinavir-ritonavir exposure in healthy subjects
-
Penzak S R., Robertson S M., Hunt J D., Chairez C, Malati C Y., Alfaro R M., Stevenson J M., Kovacs J A. Echinacea purpurea significantly induces cytochrome P450 3A activity but does not alter lopinavir-ritonavir exposure in healthy subjects. Pharmacotherapy 2010 30 797-805
-
(2010)
Pharmacotherapy
, vol.30
, pp. 797-805
-
-
Penzak, S.R.1
Robertson, S.M.2
Hunt, J.D.3
Chairez, C.4
Malati, C.Y.5
Alfaro, R.M.6
Stevenson, J.M.7
Kovacs, J.A.8
-
52
-
-
53249094298
-
Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: Comparative effects of St John's wort, echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics
-
Gurley B J., Swain A, Williams D K., Barone G, Battu S K. Gauging the clinical significance of P-glycoprotein-mediated herb-drug interactions: comparative effects of St John's wort, echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics. Mol Nutr Food Res 2008 52 772-779
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 772-779
-
-
Gurley, B.J.1
Swain, A.2
Williams, D.K.3
Barone, G.4
Battu, S.K.5
-
53
-
-
53249152208
-
A critical evaluation of drug interactions with Echinacea spp
-
Freeman C, Spelman K. A critical evaluation of drug interactions with Echinacea spp. Mol Nutr Food Res 2008 52 789-798
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 789-798
-
-
Freeman, C.1
Spelman, K.2
-
54
-
-
84890257784
-
-
In: Crozier A. Clifford M. N. Ashihara H. editors Plant secondary metabolites: occurrence, structure and role in the human diet Oxford Blackwell
-
Crozier A, Yokota T, Jaganath I B., Marks S C., Saltmarsh M, Clifford M N. Secondary metabolites in fruits, vegetables, beverages and other plant-based dietary components. In: Crozier A Clifford M N. Ashihara H editors Plant secondary metabolites: occurrence, structure and role in the human diet. Oxford Blackwell 2006 208-302
-
(2006)
Secondary Metabolites in Fruits, Vegetables, Beverages and Other Plant-based Dietary Components
, pp. 208-302
-
-
Crozier, A.1
Yokota, T.2
Jaganath, I.B.3
Marks, S.C.4
Saltmarsh, M.5
Clifford, M.N.6
-
55
-
-
0034687099
-
Garlic for treating hypercholesterolemia: A meta analysis of randomized clinical trials
-
Stevinson C, Pittler M H., Ernst E. Garlic for treating hypercholesterolemia: a meta analysis of randomized clinical trials. Ann Intern Med 2000 133 420-429
-
(2000)
Ann Intern Med
, vol.133
, pp. 420-429
-
-
Stevinson, C.1
Pittler, M.H.2
Ernst, E.3
-
56
-
-
33847339289
-
Effect of raw garlic vs. commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia
-
Gardner C D., Lawson L D., Block E, Chatterjee L M., Kiazand A, Balise R R., Kraemer H C. Effect of raw garlic vs. commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia. Arch Intern Med 2007 167 346-353
-
(2007)
Arch Intern Med
, vol.167
, pp. 346-353
-
-
Gardner, C.D.1
Lawson, L.D.2
Block, E.3
Chatterjee, L.M.4
Kiazand, A.5
Balise, R.R.6
Kraemer, H.C.7
-
57
-
-
36649006627
-
Clinical effectiveness of garlic (Allium sativum)
-
Pittler M H., Ernst E. Clinical effectiveness of garlic (Allium sativum). Mol Nutr Food Res 2007 51 1382-1385
-
(2007)
Mol Nutr Food Res
, vol.51
, pp. 1382-1385
-
-
Pittler, M.H.1
Ernst, E.2
-
58
-
-
54349087138
-
Cholesterol-lowering nutraceuticals and functional foods
-
Chen Z-Y, Jiao R, Ma K Y. Cholesterol-lowering nutraceuticals and functional foods. J Agric Food Chem 2008 56 8761-8773
-
(2008)
J Agric Food Chem
, vol.56
, pp. 8761-8773
-
-
Chen, Z.-Y.1
Jiao, R.2
Ma, K.Y.3
-
59
-
-
0025788904
-
Identification and HPLC quantitation of the sulfides and dialk(en)yl thiosulfinates in commercial garlic products
-
Lawson L D., Wang Z J., Hughes B G. Identification and HPLC quantitation of the sulfides and dialk(en)yl thiosulfinates in commercial garlic products. Planta Med 1991 57 363-370
-
(1991)
Planta Med
, vol.57
, pp. 363-370
-
-
Lawson, L.D.1
Wang, Z.J.2
Hughes, B.G.3
-
60
-
-
23844509485
-
Composition, stability, and bioavailability of garlic products used in a clinical trial
-
Lawson L D., Gardner C D. Composition, stability, and bioavailability of garlic products used in a clinical trial. J Agric Food Chem 2005 53 6254-6261
-
(2005)
J Agric Food Chem
, vol.53
, pp. 6254-6261
-
-
Lawson, L.D.1
Gardner, C.D.2
-
61
-
-
33644835000
-
Clarifying the real bioactive constituents of garlic
-
Amagase H. Clarifying the real bioactive constituents of garlic. J Nutr 2006 136 716S-725S
-
(2006)
J Nutr
, vol.136
-
-
Amagase, H.1
-
62
-
-
0035126265
-
Saponins in garlic as modifiers of the risk of cardiovascular disease
-
Matsuura H. Saponins in garlic as modifiers of the risk of cardiovascular disease. J Nutr 2001 131 1000S-1005S
-
(2001)
J Nutr
, vol.131
-
-
Matsuura, H.1
-
63
-
-
0028955174
-
On the effect of garlic oil on plasma lipids and lipoproteins in mild hypercholesterolaemia
-
Simons L A., Balasubramaniam S, von Konigsmark M, Parfitt A, Simons J, Peters W. On the effect of garlic oil on plasma lipids and lipoproteins in mild hypercholesterolaemia. Atherosclerosis 1995 113 219-225
-
(1995)
Atherosclerosis
, vol.113
, pp. 219-225
-
-
Simons, L.A.1
Balasubramaniam, S.2
Von Konigsmark, M.3
Parfitt, A.4
Simons, J.5
Peters, W.6
-
64
-
-
0032540740
-
Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism: A randomized controlled trial
-
Berthold H K., Sudhop T, von Bergman K. Effect of a garlic oil preparation on serum lipoproteins and cholesterol metabolism: a randomized controlled trial. JAMA 1998 279 1900-1902
-
(1998)
JAMA
, vol.279
, pp. 1900-1902
-
-
Berthold, H.K.1
Sudhop, T.2
Von Bergman, K.3
-
65
-
-
0034526792
-
Effect of organosulfur compounds from garlic and cruciferous vegetables on drug metabolism enzymes
-
Smith T J., Yang C S. Effect of organosulfur compounds from garlic and cruciferous vegetables on drug metabolism enzymes. Drug Metabol Drug Interact 2000 17 23-49
-
(2000)
Drug Metabol Drug Interact
, vol.17
, pp. 23-49
-
-
Smith, T.J.1
Yang, C.S.2
-
66
-
-
0035126521
-
Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic
-
Yang C S., Chhabra S K., Hong J-Y, Smith T J. Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic. J Nutr 2001 131 1041S-1045S
-
(2001)
J Nutr
, vol.131
-
-
Yang, C.S.1
Chhabra, S.K.2
Hong, J.-Y.3
Smith, T.J.4
-
67
-
-
3042692972
-
Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human, and rat CYP2E1, and rat CYP2A3
-
Morris C R., Chen S C., Zhou L, Schopfer L M., Ding X, Mirvish S S. Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human, and rat CYP2E1, and rat CYP2A3. Nutr Cancer 2004 48 54-63
-
(2004)
Nutr Cancer
, vol.48
, pp. 54-63
-
-
Morris, C.R.1
Chen, S.C.2
Zhou, L.3
Schopfer, L.M.4
Ding, X.5
Mirvish, S.S.6
-
68
-
-
33644847036
-
Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
-
Wargovich M J. Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models. J Nutr 2006 136 832S-834S
-
(2006)
J Nutr
, vol.136
-
-
Wargovich, M.J.1
-
69
-
-
33646821349
-
Formation of N-alkylprotoporphyrin IX from metabolism of diallyl sulfone in lung and liver
-
Black G P., Collins K S., Blacquiere D P., Forkert P-G. Formation of N-alkylprotoporphyrin IX from metabolism of diallyl sulfone in lung and liver. Drug Metab Dispos 2006 34 895-900
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 895-900
-
-
Black, G.P.1
Collins, K.S.2
Blacquiere, D.P.3
Forkert, P.-G.4
-
70
-
-
0028946622
-
Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes
-
Haber D, Siess M H., Canivenc-Lavier M C., Le Bon A M., Suschetet M. Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes. J Toxicol Environ Health 1995 44 423-434
-
(1995)
J Toxicol Environ Health
, vol.44
, pp. 423-434
-
-
Haber, D.1
Siess, M.H.2
Canivenc-Lavier, M.C.3
Le Bon, A.M.4
Suschetet, M.5
-
71
-
-
0030693162
-
Modification of hepatic drug-metabolizing enzymes in rats treated with alkyl sulfides
-
Siess M, Le Bon A M., Canivenc-Lavier M C., Suschetet M. Modification of hepatic drug-metabolizing enzymes in rats treated with alkyl sulfides. Cancer Lett 1997 120 195-201
-
(1997)
Cancer Lett
, vol.120
, pp. 195-201
-
-
Siess, M.1
Le Bon, A.M.2
Canivenc-Lavier, M.C.3
Suschetet, M.4
-
72
-
-
0037116438
-
Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats
-
Wu C C., Sheen L Y., Chen H-W, Kuo W W., Tsai S J., Lii C-K. Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats. J Agric Food Chem 2002 50 378-383
-
(2002)
J Agric Food Chem
, vol.50
, pp. 378-383
-
-
Wu, C.C.1
Sheen, L.Y.2
Chen, H.-W.3
Kuo, W.W.4
Tsai, S.J.5
Lii, C.-K.6
-
73
-
-
31544448252
-
Garlic organosulfur compounds upregulate the expression of the pi class of glutathione S-transferase in rat primary hepatocytes
-
Tsai C-W, Yang J-J, Chen H-W, Sheen L-Y, Lii C-K. Garlic organosulfur compounds upregulate the expression of the pi class of glutathione S-transferase in rat primary hepatocytes. J Nutr 2005 135 2560-2565
-
(2005)
J Nutr
, vol.135
, pp. 2560-2565
-
-
Tsai, C.-W.1
Yang, J.-J.2
Chen, H.-W.3
Sheen, L.-Y.4
Lii, C.-K.5
-
74
-
-
33749547150
-
Different activation patterns of rat xenobiotic metabolism genes by two constituents of garlic
-
Zhang P, Noordine M-L, Cherbuy C, Vaugelade P, Pascussi J M., Due P-H, Thomas M. Different activation patterns of rat xenobiotic metabolism genes by two constituents of garlic. Carcinogenesis 2006 27 2090-2095
-
(2006)
Carcinogenesis
, vol.27
, pp. 2090-2095
-
-
Zhang, P.1
Noordine, M.-L.2
Cherbuy, C.3
Vaugelade, P.4
Pascussi, J.M.5
Due, P.-H.6
Thomas, M.7
-
75
-
-
57149123819
-
Induction of cytochromes P450 in small intestine by chemopreventative compounds
-
Krizkova J, Burdova K, Hudecek J, Stiborova M, Hodek P. Induction of cytochromes P450 in small intestine by chemopreventative compounds. Neuro Endocrinol Lett 2008 29 717-721
-
(2008)
Neuro Endocrinol Lett
, vol.29
, pp. 717-721
-
-
Krizkova, J.1
Burdova, K.2
Hudecek, J.3
Stiborova, M.4
Hodek, P.5
-
76
-
-
70349627876
-
Induced expression of drug metabolizing enzymes by preventive agents: Role of the antioxidant response element
-
Lubet R A., Yao R, Grubbs C J., You M, Wang Y. Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element. Chem Biol Interact 2009 182 22-28
-
(2009)
Chem Biol Interact
, vol.182
, pp. 22-28
-
-
Lubet, R.A.1
Yao, R.2
Grubbs, C.J.3
You, M.4
Wang, Y.5
-
77
-
-
34249094270
-
Induction of drug metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2
-
Fisher C D., Augustine L M., Maher J M., Nelson D M., Slitt A L., Klaassen C D., Lehman-McKeeman L D., Cherrington N J. Induction of drug metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug Metab Dispos 2007 35 995-1000
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 995-1000
-
-
Fisher, C.D.1
Augustine, L.M.2
Maher, J.M.3
Nelson, D.M.4
Slitt, A.L.5
Klaassen, C.D.6
Lehman-Mckeeman, L.D.7
Cherrington, N.J.8
-
78
-
-
67650147038
-
In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients
-
Engdal S, Nilsen O G. In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients. Phytother Res 2009 23 906-912
-
(2009)
Phytother Res
, vol.23
, pp. 906-912
-
-
Engdal, S.1
Nilsen, O.G.2
-
79
-
-
0037119057
-
Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity
-
Zou L, Harkey M R., Henderson G L. Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity. Life Sci 2002 71 1579-1589
-
(2002)
Life Sci
, vol.71
, pp. 1579-1589
-
-
Zou, L.1
Harkey, M.R.2
Henderson, G.L.3
-
80
-
-
0035735338
-
An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic
-
Foster B C., Foster M S., Vandenhoek S, Krantis A, Budzinski J W., Arnason J T., Gallicano K D., Choudri S. An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic. J Pharm Pharmaceut Sci 2001 4 176-184
-
(2001)
J Pharm Pharmaceut Sci
, vol.4
, pp. 176-184
-
-
Foster, B.C.1
Foster, M.S.2
Vandenhoek, S.3
Krantis, A.4
Budzinski, J.W.5
Arnason, J.T.6
Gallicano, K.D.7
Choudri, S.8
-
81
-
-
33644841936
-
In vitro interactions of water-soluble garlic components with human cytochromes P450
-
Greenblatt D J., Leigh-Pemberton R A., von Moltke L L. In vitro interactions of water-soluble garlic components with human cytochromes P450. J Nutr 2006 136 806S-809S
-
(2006)
J Nutr
, vol.136
-
-
Greenblatt, D.J.1
Leigh-Pemberton, R.A.2
Von Moltke, L.L.3
-
82
-
-
11844301652
-
Effects of dietary chemopreventative phytochemicals on P-glycoprotein function
-
Nabekura T, Kamiyama S, Kitagawa S. Effects of dietary chemopreventative phytochemicals on P-glycoprotein function. Biochem Biophys Res Commun 2005 327 866-870
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 866-870
-
-
Nabekura, T.1
Kamiyama, S.2
Kitagawa, S.3
-
83
-
-
45849091909
-
Inhibition of P-glycoprotein in Caco-2 cells: Effects of herbal remedies frequently used by cancer patients
-
Engdal S, Nilsen O G. Inhibition of P-glycoprotein in Caco-2 cells: effects of herbal remedies frequently used by cancer patients. Xenobiotica 2008 38 559-573
-
(2008)
Xenobiotica
, vol.38
, pp. 559-573
-
-
Engdal, S.1
Nilsen, O.G.2
-
84
-
-
3042814442
-
Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver
-
Arora A, Seth K, Shukla Y. Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver. Carcinogenesis 2004 25 941-949
-
(2004)
Carcinogenesis
, vol.25
, pp. 941-949
-
-
Arora, A.1
Seth, K.2
Shukla, Y.3
-
85
-
-
5144232445
-
Diallyl disulfide, a chemopreventive agent in garlic, induces multidrug resistance-associated protein 2 expression
-
Demeule M, Brossard M, Turcotte S, Regina A, Jodoin J, Bliveau R. Diallyl disulfide, a chemopreventive agent in garlic, induces multidrug resistance-associated protein 2 expression. Biochem Biophys Res Commun 2004 324 937-945
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 937-945
-
-
Demeule, M.1
Brossard, M.2
Turcotte, S.3
Regina, A.4
Jodoin, J.5
Bliveau, R.6
-
86
-
-
65249173973
-
Aged garlic extract stimulates P-glycoprotein and multidrug resistance associated protein 2 mediated effluxes
-
Berginc K, Zakelj S, Ursic D, Kristl A. Aged garlic extract stimulates P-glycoprotein and multidrug resistance associated protein 2 mediated effluxes. Biol Pharm Bull 2009 32 694-699
-
(2009)
Biol Pharm Bull
, vol.32
, pp. 694-699
-
-
Berginc, K.1
Zakelj, S.2
Ursic, D.3
Kristl, A.4
-
87
-
-
77955851957
-
In vitro interactions between aged garlic extract and drugs used for the treatment of cardiovascular and diabetes patients
-
Berginc K, Zakelj S, Kristl A. In vitro interactions between aged garlic extract and drugs used for the treatment of cardiovascular and diabetes patients. Eur J Nutr 2010 49 373-384
-
(2010)
Eur J Nutr
, vol.49
, pp. 373-384
-
-
Berginc, K.1
Zakelj, S.2
Kristl, A.3
-
88
-
-
77954346375
-
The influence of aged garlic extract on the uptake of saquinavir and darunavir into HepG2 cells and rat liver slices
-
Berginc K, Trontelj J, Kristl A. The influence of aged garlic extract on the uptake of saquinavir and darunavir into HepG2 cells and rat liver slices. Drug Metab Pharmacokinet 2010 25 307-313
-
(2010)
Drug Metab Pharmacokinet
, vol.25
, pp. 307-313
-
-
Berginc, K.1
Trontelj, J.2
Kristl, A.3
-
89
-
-
0036021113
-
The drug efflux pump MRP-2: Regulation of expression in physiopathological situations by endogenous and exogenous compounds
-
Payen L, Sparfel L, Courtois A, Vernhet L, Guillouzo A, Fardel O. The drug efflux pump MRP-2: regulation of expression in physiopathological situations by endogenous and exogenous compounds. Cell Biol Toxicol 2002 18 221-233
-
(2002)
Cell Biol Toxicol
, vol.18
, pp. 221-233
-
-
Payen, L.1
Sparfel, L.2
Courtois, A.3
Vernhet, L.4
Guillouzo, A.5
Fardel, O.6
-
90
-
-
0036736521
-
Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans
-
Gurley B J., Gardner S F., Hubbard M A., Williams D K., Gentry W B., Cui Y, Ang C Y. W. Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans. Clin Pharmacol Ther 2002 72 276-287
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 276-287
-
-
Gurley, B.J.1
Gardner, S.F.2
Hubbard, M.A.3
Williams, D.K.4
Gentry, W.B.5
Cui, Y.6
Ang, C.Y.W.7
-
91
-
-
0028239629
-
The effect of garlic extract on human metabolism of acetaminophen
-
Gwilt P R., Lear C L., Tempero M A., Birt D D., Grandjean A C., Ruddon R W., Nagel D L. The effect of garlic extract on human metabolism of acetaminophen. Cancer Epidemiol Biomarkers Prev 1994 3 155-160
-
(1994)
Cancer Epidemiol Biomarkers Prev
, vol.3
, pp. 155-160
-
-
Gwilt, P.R.1
Lear, C.L.2
Tempero, M.A.3
Birt, D.D.4
Grandjean, A.C.5
Ruddon, R.W.6
Nagel, D.L.7
-
92
-
-
0034874878
-
The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: A phenotyping study using chlorzoxazone
-
Loizou G D., Crocker J. The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone. Hum Exp Toxicol 2001 20 321-327
-
(2001)
Hum Exp Toxicol
, vol.20
, pp. 321-327
-
-
Loizou, G.D.1
Crocker, J.2
-
93
-
-
0037079915
-
The effect of garlic supplements on the pharmacokinetics of saquinavir
-
Piscitelli S C., Burstein A H., Welden N, Gallicano K D., Falloon J. The effect of garlic supplements on the pharmacokinetics of saquinavir. Clin Infect Dis 2002 34 234-238
-
(2002)
Clin Infect Dis
, vol.34
, pp. 234-238
-
-
Piscitelli, S.C.1
Burstein, A.H.2
Welden, N.3
Gallicano, K.D.4
Falloon, J.5
-
94
-
-
0037329811
-
Effect of short-term administration of garlic supplements on single-dose pharmacokinetics in healthy volunteers
-
Gallicano K, Foster B, Choudri S. Effect of short-term administration of garlic supplements on single-dose pharmacokinetics in healthy volunteers. Br J Clin Pharmacol 2003 55 199-202
-
(2003)
Br J Clin Pharmacol
, vol.55
, pp. 199-202
-
-
Gallicano, K.1
Foster, B.2
Choudri, S.3
-
95
-
-
0043128560
-
Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers
-
Markowitz J S., DeVane L, Chavin K D., Taylor R M., Ruan Y, Donovan J L. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers. Clin Pharmacol Ther 2003 74 170-177
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 170-177
-
-
Markowitz, J.S.1
Devane, L.2
Chavin, K.D.3
Taylor, R.M.4
Ruan, Y.5
Donovan, J.L.6
-
96
-
-
33646742985
-
No effect of garlic extract on saquinavir kinetics and hepatic CYP3A4 function measured by the erythromycin breath test [Abstr]
-
Jacek H, Rentsch K M., Steinert H C., Pauli-Magnus C, Meier P J., Fattinger K. No effect of garlic extract on saquinavir kinetics and hepatic CYP3A4 function measured by the erythromycin breath test [Abstr]. Clin Pharmacol Ther 2004 75 80
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 80
-
-
Jacek, H.1
Rentsch, K.M.2
Steinert, H.C.3
Pauli-Magnus, C.4
Meier, P.J.5
Fattinger, K.6
-
97
-
-
23244443393
-
Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in renal transplant recipients
-
Jabbari A, Argani H, Ghorbanihaghjo A, Mahdavi R. Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in renal transplant recipients. Lipids Health Dis 2005 4 11
-
(2005)
Lipids Health Dis
, vol.4
, pp. 11
-
-
Jabbari, A.1
Argani, H.2
Ghorbanihaghjo, A.3
Mahdavi, R.4
-
98
-
-
22344453862
-
Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba
-
Gurley B J., Gardner S F., Hubbard M A., Williams D K., Gentry W B., Cui Y, Ang C Y. W. Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba. Drugs Aging 2005 22 525-539
-
(2005)
Drugs Aging
, vol.22
, pp. 525-539
-
-
Gurley, B.J.1
Gardner, S.F.2
Hubbard, M.A.3
Williams, D.K.4
Gentry, W.B.5
Cui, Y.6
Ang, C.Y.W.7
-
99
-
-
33748087822
-
Influence of garlic (Allium sativum) on the pharmacokinetics of docetaxel
-
Cox M C., Low J, Lee J, Walshe J, Denduluri N, Berman A, Permenter M G., Petros W P., Proce D K., Figg W D., Sparreboom A, Swain S M. Influence of garlic (Allium sativum) on the pharmacokinetics of docetaxel. Clin Cancer Res 2006 12 4636-4640
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4636-4640
-
-
Cox, M.C.1
Low, J.2
Lee, J.3
Walshe, J.4
Denduluri, N.5
Berman, A.6
Permenter, M.G.7
Petros, W.P.8
Proce, D.K.9
Figg, W.D.10
Sparreboom, A.11
Swain, S.M.12
-
100
-
-
33644847423
-
Aged garlic extract may be safe for patients on warfarin therapy
-
Macan H, Uykimpang R, Alconcel M, Takasu J, Razon R, Amagase H, Niihara Y. Aged garlic extract may be safe for patients on warfarin therapy. J Nutr 2006 136 793S-795S
-
(2006)
J Nutr
, vol.136
-
-
MacAn, H.1
Uykimpang, R.2
Alconcel, M.3
Takasu, J.4
Razon, R.5
Amagase, H.6
Niihara, Y.7
-
101
-
-
49449094988
-
Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects
-
Abdul M I. M., Jiang X, Willaims K M., Day R O., Roufogalis B D., Liauw W S., Ku H, McLachlan A J. Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects. Br J Pharmacol 2008 154 1691-1700
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1691-1700
-
-
Abdul, M.I.M.1
Jiang, X.2
Willaims, K.M.3
Day, R.O.4
Roufogalis, B.D.5
Liauw, W.S.6
Ku, H.7
McLachlan, A.J.8
-
102
-
-
68849086426
-
Effects of allicin on CYP2C19 and CYP3A4 activity in healthy volunteers with different CYP2C19 genotypes
-
Yang L-J, Fan L, Liu Z-Q, Mao Y-M, Guo D, Liu L-H, Tan Z-R, Peng L, Han C-T, Hu D-L, Wang D, Zhou H-H. Effects of allicin on CYP2C19 and CYP3A4 activity in healthy volunteers with different CYP2C19 genotypes. Eur J Clin Pharmacol 2009 65 601-608
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 601-608
-
-
Yang, L.-J.1
Fan, L.2
Liu, Z.-Q.3
Mao, Y.-M.4
Guo, D.5
Liu, L.-H.6
Tan, Z.-R.7
Peng, L.8
Han, C.-T.9
Hu, D.-L.10
Wang, D.11
Zhou, H.-H.12
-
103
-
-
78349305570
-
Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans
-
Hajda J, Rentsch K M., Gubler C, Steinert H, Stieger B, Fattinger K. Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans. Eur J Pharm Sci 2010 41 729-735
-
(2010)
Eur J Pharm Sci
, vol.41
, pp. 729-735
-
-
Hajda, J.1
Rentsch, K.M.2
Gubler, C.3
Steinert, H.4
Stieger, B.5
Fattinger, K.6
-
104
-
-
34548321002
-
Ginkgo biloba leaves extract: Biological, medicinal, and toxicological effects
-
Chan P-C, Xia Q, Fu P P. Ginkgo biloba leaves extract: biological, medicinal, and toxicological effects. J Environ Sci Health C 2007 25 211-244
-
(2007)
J Environ Sci Health C
, vol.25
, pp. 211-244
-
-
Chan, P.-C.1
Xia, Q.2
Fu, P.P.3
-
105
-
-
12344295476
-
Clinical use and molecular mechanisms of action of extract of Ginkgo biloba leaves in cardiovascular diseases
-
Zhou W, Chai H, Lin P H., Lumsden A B., Yao Q, Chen C. Clinical use and molecular mechanisms of action of extract of Ginkgo biloba leaves in cardiovascular diseases. Cardiovasc Drug Rev 2004 22 309-319
-
(2004)
Cardiovasc Drug Rev
, vol.22
, pp. 309-319
-
-
Zhou, W.1
Chai, H.2
Lin, P.H.3
Lumsden, A.B.4
Yao, Q.5
Chen, C.6
-
106
-
-
34547528111
-
Ginkgo biloba is not a smart drug: An updated systematic review of randomized clinical trials testing the nootropic effects of G. biloba extracts in healthy people
-
Canter P H., Ernst E. Ginkgo biloba is not a smart drug: an updated systematic review of randomized clinical trials testing the nootropic effects of G. biloba extracts in healthy people. Hum Psychopharmacol 2007 22 265-278
-
(2007)
Hum Psychopharmacol
, vol.22
, pp. 265-278
-
-
Canter, P.H.1
Ernst, E.2
-
107
-
-
34347370406
-
Ginkgo blioba extract (EGb 761) in Alzheimer's disease: Is there any evidence
-
Ramassamy C, Longpr F, Christen Y. Ginkgo blioba extract (EGb 761) in Alzheimer's disease: is there any evidence? Curr Alzheimer Res 2007 4 253-262
-
(2007)
Curr Alzheimer Res
, vol.4
, pp. 253-262
-
-
Ramassamy, C.1
Longpr, F.2
Christen, Y.3
-
110
-
-
0036231404
-
Pharmaceutical quality of different Ginkgo biloba brands
-
Kressman S, Mller W E., Blume H H. Pharmaceutical quality of different Ginkgo biloba brands. J Pharm Pharmacol 2002 54 661-669
-
(2002)
J Pharm Pharmacol
, vol.54
, pp. 661-669
-
-
Kressman, S.1
Mller, W.E.2
Blume, H.H.3
-
111
-
-
77349104616
-
Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans
-
Woelkert K, Feizlmayr E, Dittrich P, Beubler E, Pinl F, Suter A, Bauer R. Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans. Phytother Res 2010 24 445-450
-
(2010)
Phytother Res
, vol.24
, pp. 445-450
-
-
Woelkert, K.1
Feizlmayr, E.2
Dittrich, P.3
Beubler, E.4
Pinl, F.5
Suter, A.6
Bauer, R.7
-
112
-
-
34547730805
-
An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constituents
-
Etheridge A S., Black S R., Patel P R., So J, Mathews J M. An in vitro evaluation of cytochrome P450 inhibition and P-glycoprotein interaction with goldenseal, Ginkgo biloba, grape seed, milk thistle, and ginseng extracts and their constituents. Planta Med 2007 73 731-741
-
(2007)
Planta Med
, vol.73
, pp. 731-741
-
-
Etheridge, A.S.1
Black, S.R.2
Patel, P.R.3
So, J.4
Mathews, J.M.5
-
113
-
-
33845996201
-
The induction of CYP1A2, CYP2D6 and CYP3A4 by six trade herbal products in cultured primary human hepatocytes
-
Hellum B H., Hu Z, Nilsen O G. The induction of CYP1A2, CYP2D6 and CYP3A4 by six trade herbal products in cultured primary human hepatocytes. Basic Clin Pharmacol Toxicol 2007 100 23-30
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.100
, pp. 23-30
-
-
Hellum, B.H.1
Hu, Z.2
Nilsen, O.G.3
-
114
-
-
67651208865
-
Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
-
Hellum B H., Hu Z, Nilsen O G. Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes. Basic Clin Pharmacol Toxicol 2009 105 58-63
-
(2009)
Basic Clin Pharmacol Toxicol
, vol.105
, pp. 58-63
-
-
Hellum, B.H.1
Hu, Z.2
Nilsen, O.G.3
-
115
-
-
2442534164
-
Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract
-
Gaudineau C, Beckerman R, Welbourn S, Auclair K. Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract. Biochem Biophys Res Commun 2004 318 1072-1078
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 1072-1078
-
-
Gaudineau, C.1
Beckerman, R.2
Welbourn, S.3
Auclair, K.4
-
116
-
-
33646131391
-
Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: Identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1
-
Chang T K. H., Chen J, Yeung E Y. H. Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1. Toxicol Appl Pharmacol 2006 213 18-26
-
(2006)
Toxicol Appl Pharmacol
, vol.213
, pp. 18-26
-
-
Chang, T.K.H.1
Chen, J.2
Yeung, E.Y.H.3
-
117
-
-
36549024380
-
Effect of Ginkgo biloba extract on oxidative metaolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype
-
Numa A M., Abbott F S., Chang T K. H. Effect of Ginkgo biloba extract on oxidative metaolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype. Can J Physiol Pharmacol 2007 85 848-855
-
(2007)
Can J Physiol Pharmacol
, vol.85
, pp. 848-855
-
-
Numa, A.M.1
Abbott, F.S.2
Chang, T.K.H.3
-
118
-
-
70349142732
-
Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: Effect of terpene trilactones and flavonols
-
Lau A J., Chang T K. H. Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: effect of terpene trilactones and flavonols. Drug Metab Dispos 2009 37 1931-1937
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1931-1937
-
-
Lau, A.J.1
Chang, T.K.H.2
-
119
-
-
76149099869
-
Inhibition of intestinal and hepatic glucuronidation of mycophenolic acid by Ginkgo biloba extract and flavonoids
-
Mohamed M F., Frye R F. Inhibition of intestinal and hepatic glucuronidation of mycophenolic acid by Ginkgo biloba extract and flavonoids. Drug Metab Dispos 2010 38 270-275
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 270-275
-
-
Mohamed, M.F.1
Frye, R.F.2
-
120
-
-
3843064658
-
The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes
-
He N, Edeki T. The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes. Am J Ther 2004 11 206-212
-
(2004)
Am J Ther
, vol.11
, pp. 206-212
-
-
He, N.1
Edeki, T.2
-
121
-
-
72149090100
-
Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity
-
Kimura Y, Ito H, Ohnishi R, Hatano T. Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity. Food Chem Toxicol 2010 48 429-435
-
(2010)
Food Chem Toxicol
, vol.48
, pp. 429-435
-
-
Kimura, Y.1
Ito, H.2
Ohnishi, R.3
Hatano, T.4
-
122
-
-
77953591766
-
In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity
-
Tiong K H., Yiap B C., Tan E L., Ismail R, Ong C E. In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity. Xenobiotica 2010 40 458-466
-
(2010)
Xenobiotica
, vol.40
, pp. 458-466
-
-
Tiong, K.H.1
Yiap, B.C.2
Tan, E.L.3
Ismail, R.4
Ong, C.E.5
-
123
-
-
1842454858
-
Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: Role of ginkgolides, bilobalide, and flavonols
-
Kuo I F., Chen J, Chang T K. H. Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: role of ginkgolides, bilobalide, and flavonols. Can J Physiol Pharmacol 2004 82 57-64
-
(2004)
Can J Physiol Pharmacol
, vol.82
, pp. 57-64
-
-
Kuo, I.F.1
Chen, J.2
Chang, T.K.H.3
-
124
-
-
4344616168
-
Inhibition of human cytochromes P450 by components of Ginkgo biloba
-
von Moltke L L., Weemhoff J L., Bedir E, Khan I A., Harmatz J S., Goldman P, Greenblatt D J. Inhibition of human cytochromes P450 by components of Ginkgo biloba. J Pharm Pharmacol 2004 56 1039-1044
-
(2004)
J Pharm Pharmacol
, vol.56
, pp. 1039-1044
-
-
Von Moltke, L.L.1
Weemhoff, J.L.2
Bedir, E.3
Khan, I.A.4
Harmatz, J.S.5
Goldman, P.6
Greenblatt, D.J.7
-
125
-
-
0037154405
-
Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450
-
Hodek P, Trefil P, Stiborov M. Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450. Chem Biol Interact 2002 139 1-21
-
(2002)
Chem Biol Interact
, vol.139
, pp. 1-21
-
-
Hodek, P.1
Trefil, P.2
Stiborov, M.3
-
126
-
-
61449170185
-
Mechanism of CYP2C9 inhibition by flavones and flavonols
-
Si D, Wang Y, Zhou Y-H, Guo Y, Wang J, Zhou H, Li Z-S, Fawcett J P. Mechanism of CYP2C9 inhibition by flavones and flavonols. Drug Metab Dispos 2009 37 629-634
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 629-634
-
-
Si, D.1
Wang, Y.2
Zhou, Y.-H.3
Guo, Y.4
Wang, J.5
Zhou, H.6
Li, Z.-S.7
Fawcett, J.P.8
-
127
-
-
33747066115
-
Effects of individual ginsenosides, ginkgolides and flavonoids on CYP2C19 and CYP2D6 activity in human liver microsomes
-
He N, Xie H-G, Collins X, Edeki T, Yan Z. Effects of individual ginsenosides, ginkgolides and flavonoids on CYP2C19 and CYP2D6 activity in human liver microsomes. Clin Exp Pharmacol Physiol 2006 33 813-815
-
(2006)
Clin Exp Pharmacol Physiol
, vol.33
, pp. 813-815
-
-
He, N.1
Xie, H.-G.2
Collins, X.3
Edeki, T.4
Yan, Z.5
-
128
-
-
31344477335
-
Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes
-
Chang T K. H., Chen J, Teng X W. Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes. Drug Metab Dispos 2006 34 234-242
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 234-242
-
-
Chang, T.K.H.1
Chen, J.2
Teng, X.W.3
-
129
-
-
54349103738
-
Identification of Ginkgo biloba as a novel activator of pregnane X receptor
-
Yeung E Y. H., Sueyoshi T, Negishi M, Chang T H. K. Identification of Ginkgo biloba as a novel activator of pregnane X receptor. Drug Metab Dispos 2008 36 2270-2276
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 2270-2276
-
-
Yeung, E.Y.H.1
Sueyoshi, T.2
Negishi, M.3
Chang, T.H.K.4
-
130
-
-
40949101425
-
Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes
-
Deng Y, Bi H C., Zhao L Z., Wang X D., Chen J, Ou Z M., Ding L, Xu L J., Guan S, Chen X, Zhou S F., Huang M. Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes. Drug Metab Lett 2008 2 60-66
-
(2008)
Drug Metab Lett
, vol.2
, pp. 60-66
-
-
Deng, Y.1
Bi, H.C.2
Zhao, L.Z.3
Wang, X.D.4
Chen, J.5
Ou, Z.M.6
Ding, L.7
Xu, L.J.8
Guan, S.9
Chen, X.10
Zhou, S.F.11
Huang, M.12
-
131
-
-
61449220882
-
Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways
-
Li L, Stanton J D., Tolson A H., Luo Y, Wang H. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. Pharm Res 2009 26 872-882
-
(2009)
Pharm Res
, vol.26
, pp. 872-882
-
-
Li, L.1
Stanton, J.D.2
Tolson, A.H.3
Luo, Y.4
Wang, H.5
-
132
-
-
70349297460
-
Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells
-
Rajaraman G, Yang G, Chen J, Chang T H. K. Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells. Can J Physiol Pharmacol 2009 87 674-683
-
(2009)
Can J Physiol Pharmacol
, vol.87
, pp. 674-683
-
-
Rajaraman, G.1
Yang, G.2
Chen, J.3
Chang, T.H.K.4
-
133
-
-
47849122700
-
Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals
-
Satsu H, Hiura Y, Mochizuki K, Hamada M, Shimizu M. Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals. J Agric Food Chem 2008 56 5366-5373
-
(2008)
J Agric Food Chem
, vol.56
, pp. 5366-5373
-
-
Satsu, H.1
Hiura, Y.2
Mochizuki, K.3
Hamada, M.4
Shimizu, M.5
-
134
-
-
0041511846
-
Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits
-
Jeuken A, Keser B J. G., Khan E, Brouwer A, Koeman J, Denison M S. Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. J Agric Food Chem 2003 51 5478-5487
-
(2003)
J Agric Food Chem
, vol.51
, pp. 5478-5487
-
-
Jeuken, A.1
Keser, B.J.G.2
Khan, E.3
Brouwer, A.4
Koeman, J.5
Denison, M.S.6
-
135
-
-
0037154807
-
Effects of extract of Ginkgo biloba leaves and its constituents on carcinogen-metabolizing enzyme activities and glutathione levels in mouse liver
-
Sasaki K, Hatta S, Wada K, Ueda N, Yoshimura T, Endo T, Sakata M, Tanaka T, Haga M. Effects of extract of Ginkgo biloba leaves and its constituents on carcinogen-metabolizing enzyme activities and glutathione levels in mouse liver. Life Sci 2002 70 1657-1667
-
(2002)
Life Sci
, vol.70
, pp. 1657-1667
-
-
Sasaki, K.1
Hatta, S.2
Wada, K.3
Ueda, N.4
Yoshimura, T.5
Endo, T.6
Sakata, M.7
Tanaka, T.8
Haga, M.9
-
136
-
-
0036951332
-
Ginkgo biloba extract markedly induces pentoxyresorufin O-dealkylase activity in rats
-
Umegaki K, Saito K, Kubota Y, Sanada H, Yamada K, Shinozuka K. Ginkgo biloba extract markedly induces pentoxyresorufin O-dealkylase activity in rats. Jpn J Pharmacol 2002 90 345-351
-
(2002)
Jpn J Pharmacol
, vol.90
, pp. 345-351
-
-
Umegaki, K.1
Saito, K.2
Kubota, Y.3
Sanada, H.4
Yamada, K.5
Shinozuka, K.6
-
137
-
-
0141926452
-
Effects of Ginkgo biloba extract and tanshinone on cytochrome P-450 isozymes and glutathione transferase in rats
-
Yang X F., Wang N P., Lu W H., Zeng F D. Effects of Ginkgo biloba extract and tanshinone on cytochrome P-450 isozymes and glutathione transferase in rats. Acta Pharmacol Sin 2003 24 1033-1038
-
(2003)
Acta Pharmacol Sin
, vol.24
, pp. 1033-1038
-
-
Yang, X.F.1
Wang, N.P.2
Lu, W.H.3
Zeng, F.D.4
-
138
-
-
1942534088
-
Induction and recovery of hepatic drug metabolizing enzymes in rats treated with Ginkgo biloba extract
-
Sugiyama T, Kubota Y, Shinozuka K, Yamada S, Yamada K, Umegaki K. Induction and recovery of hepatic drug metabolizing enzymes in rats treated with Ginkgo biloba extract. Food Chem Toxicol 2004 42 953-957
-
(2004)
Food Chem Toxicol
, vol.42
, pp. 953-957
-
-
Sugiyama, T.1
Kubota, Y.2
Shinozuka, K.3
Yamada, S.4
Yamada, K.5
Umegaki, K.6
-
139
-
-
17644384321
-
Influence of the Ginkgo extract EGb 761 on rat liver cytochrome P450 and steroid metabolism and excretion in rats and man
-
Chatterjee S S., Doelman C J., Nöldner M, Biber A, Koch E. Influence of the Ginkgo extract EGb 761 on rat liver cytochrome P450 and steroid metabolism and excretion in rats and man. J Pharm Pharmacol 2005 57 641-650
-
(2005)
J Pharm Pharmacol
, vol.57
, pp. 641-650
-
-
Chatterjee, S.S.1
Doelman, C.J.2
Nöldner, M.3
Biber, A.4
Koch, E.5
-
140
-
-
77049094690
-
Ginkgo biloba extract induces gene expression changes in xenobiotics metabolism and the Myc-centered network
-
Guo L, Mei N, Liao W, Chan P-C, Fu P P. Ginkgo biloba extract induces gene expression changes in xenobiotics metabolism and the Myc-centered network. Omics 2010 14 75-89
-
(2010)
Omics
, vol.14
, pp. 75-89
-
-
Guo, L.1
Mei, N.2
Liao, W.3
Chan, P.-C.4
Fu, P.P.5
-
141
-
-
0037177470
-
Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates the hypotensive effect of nicardipine in rats
-
Shinozuka K, Umekagi K, Kubota Y, Tanaka N, Mizuno H, Yamauchi J, Nakamura K, Kunitomo M. Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates the hypotensive effect of nicardipine in rats. Life Sci 2002 70 2783-2792
-
(2002)
Life Sci
, vol.70
, pp. 2783-2792
-
-
Shinozuka, K.1
Umekagi, K.2
Kubota, Y.3
Tanaka, N.4
Mizuno, H.5
Yamauchi, J.6
Nakamura, K.7
Kunitomo, M.8
-
142
-
-
2942689532
-
Ginkgo biloba extract modifies hypoglycemic action of tolbutamide via hepatic cytochrome P450 mediated mechanism in aged rats
-
Sugiyama T, Kubota Y, Shinozuka K, Yamada S, Wu J, Umegaki K. Ginkgo biloba extract modifies hypoglycemic action of tolbutamide via hepatic cytochrome P450 mediated mechanism in aged rats. Life Sci 2004 75 1113-1122
-
(2004)
Life Sci
, vol.75
, pp. 1113-1122
-
-
Sugiyama, T.1
Kubota, Y.2
Shinozuka, K.3
Yamada, S.4
Wu, J.5
Umegaki, K.6
-
143
-
-
1642402247
-
Pretreatment with Ginkgo biloba extract weakens the hypnosis action of phenobarbital and its plasma concentration in rats
-
Kubota Y, Kobayashi K, Tanaka N, Nakamura K, Kunimoto M, Umegaki K, Shinozuka K. Pretreatment with Ginkgo biloba extract weakens the hypnosis action of phenobarbital and its plasma concentration in rats. J Pharm Pharmacol 2004 56 401-405
-
(2004)
J Pharm Pharmacol
, vol.56
, pp. 401-405
-
-
Kubota, Y.1
Kobayashi, K.2
Tanaka, N.3
Nakamura, K.4
Kunimoto, M.5
Umegaki, K.6
Shinozuka, K.7
-
144
-
-
33747185368
-
Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats
-
Zhao L-Z, Huang M, Chen J, Ee P L. R., Chan E, Duan W, Guan Y-Y, Hong Y-H, Chen X, Zhou S. Induction of propranolol metabolism by Ginkgo biloba extract EGb 761 in rats. Curr Drug Metab 2006 7 577-587
-
(2006)
Curr Drug Metab
, vol.7
, pp. 577-587
-
-
Zhao, L.-Z.1
Huang, M.2
Chen, J.3
Ee, P.L.R.4
Chan, E.5
Duan, W.6
Guan, Y.-Y.7
Hong, Y.-H.8
Chen, X.9
Zhou, S.10
-
145
-
-
33745591079
-
Marked decrease of cyclosporine bioavailability caused by coadministration of ginkgo and onion in rats
-
Yang C Y., Chao P D. L., Hou Y C., Tsai S Y., Wen K C., Hsiu S L. Marked decrease of cyclosporine bioavailability caused by coadministration of ginkgo and onion in rats. Food Chem Toxicol 2006 44 1572-1578
-
(2006)
Food Chem Toxicol
, vol.44
, pp. 1572-1578
-
-
Yang, C.Y.1
Chao, P.D.L.2
Hou, Y.C.3
Tsai, S.Y.4
Wen, K.C.5
Hsiu, S.L.6
-
146
-
-
35348982778
-
Herb-drug interactions: Effect of Ginkgo biloba extract on the pharmacokinetics of theophylline in rats
-
Tang J, Sun J, Zhang Y, Li L, Cui F, He Z. Herb-drug interactions: effect of Ginkgo biloba extract on the pharmacokinetics of theophylline in rats. Food Chem Toxicol 2007 45 2441-2445
-
(2007)
Food Chem Toxicol
, vol.45
, pp. 2441-2445
-
-
Tang, J.1
Sun, J.2
Zhang, Y.3
Li, L.4
Cui, F.5
He, Z.6
-
147
-
-
33750706162
-
Ginkgolide A contributes to the potentiation of acetaminophen toxicity by Ginkgo biloba extract in primary cultures of rat hepatocytes
-
Rajaraman G, Chen J, Chang T K. H. Ginkgolide A contributes to the potentiation of acetaminophen toxicity by Ginkgo biloba extract in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol 2006 217 225-233
-
(2006)
Toxicol Appl Pharmacol
, vol.217
, pp. 225-233
-
-
Rajaraman, G.1
Chen, J.2
Chang, T.K.H.3
-
148
-
-
34447305252
-
Bilobalide in Ginkgo biloba extract is a major substance inducing hepatic CYPs
-
Umegaki K, Taki Y, Endoh K, Taku K, Tanabe H, Shinozuka K, Sugiyama T. Bilobalide in Ginkgo biloba extract is a major substance inducing hepatic CYPs. J Pharm Pharmacol 2007 59 871-877
-
(2007)
J Pharm Pharmacol
, vol.59
, pp. 871-877
-
-
Umegaki, K.1
Taki, Y.2
Endoh, K.3
Taku, K.4
Tanabe, H.5
Shinozuka, K.6
Sugiyama, T.7
-
149
-
-
42249107140
-
Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats
-
Deng Y, Bi H-C, Zhao L-Z, He F, Liu Y-Q, Yu J-J, Ou Z-M, Ding L, Huang Z-Y, Huang M, Zhou S-F. Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats. Xenobiotica 2008 38 465-481
-
(2008)
Xenobiotica
, vol.38
, pp. 465-481
-
-
Deng, Y.1
Bi, H.-C.2
Zhao, L.-Z.3
He, F.4
Liu, Y.-Q.5
Yu, J.-J.6
Ou, Z.-M.7
Ding, L.8
Huang, Z.-Y.9
Huang, M.10
Zhou, S.-F.11
-
150
-
-
67249136680
-
Time-dependent induction of hepatic cytochrome P450 enzyme activity and mRNA expression by bilobalide in rats
-
Taki Y, Yamazaki Y, Shimura F, Yamada S, Umegaki K. Time-dependent induction of hepatic cytochrome P450 enzyme activity and mRNA expression by bilobalide in rats. J Pharmacol Sci 2009 109 459-462
-
(2009)
J Pharmacol Sci
, vol.109
, pp. 459-462
-
-
Taki, Y.1
Yamazaki, Y.2
Shimura, F.3
Yamada, S.4
Umegaki, K.5
-
151
-
-
11144232127
-
Pharmacogenetics and herb-drug interactions: Experience with Ginkgo biloba and omeprazole
-
Yin O Q. P., Tomlinson B, Waye M M. Y., Chow A H. L., Chow M S. S. Pharmacogenetics and herb-drug interactions: experience with Ginkgo biloba and omeprazole. Pharmacogenetics 2004 14 841-850
-
(2004)
Pharmacogenetics
, vol.14
, pp. 841-850
-
-
Yin, O.Q.P.1
Tomlinson, B.2
Waye, M.M.Y.3
Chow, A.H.L.4
Chow, M.S.S.5
-
152
-
-
0024338343
-
Effect of Ginkgo biloba extract on microsomal enzyme induction
-
Duche J C., Barre J, Guinot P, Duchier J, Cournot A, Tillement J P. Effect of Ginkgo biloba extract on microsomal enzyme induction. Int J Clin Pharm Res 1989 9 165-168
-
(1989)
Int J Clin Pharm Res
, vol.9
, pp. 165-168
-
-
Duche, J.C.1
Barre, J.2
Guinot, P.3
Duchier, J.4
Cournot, A.5
Tillement, J.P.6
-
153
-
-
14144254049
-
An open trial of nifedipine-herb interactions: Nifedipine with St John's wort, ginseng, or Ginkgo biloba [Abstr.]
-
Smith M, Lin K M., Zheng Y P. An open trial of nifedipine-herb interactions: nifedipine with St John's wort, ginseng, or Ginkgo biloba [Abstr.]. Clin Pharmacol Ther 2001 69 P86
-
(2001)
Clin Pharmacol Ther
, vol.69
-
-
Smith, M.1
Lin, K.M.2
Zheng, Y.P.3
-
154
-
-
4344632236
-
A high-throughput cocktail method for screening the effect of herbal product on liver isozyme activities: Experience with Ginkgo biloba
-
Sun H, Zuo Z, Yin O Q., Tomlinson B, Chow M S. A high-throughput cocktail method for screening the effect of herbal product on liver isozyme activities: experience with Ginkgo biloba. Clin Pharmacol Ther 2002 71 P100
-
(2002)
Clin Pharmacol Ther
, vol.71
-
-
Sun, H.1
Zuo, Z.2
Yin, O.Q.3
Tomlinson, B.4
Chow, M.S.5
-
155
-
-
0036281554
-
Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomized, double blind, placebo-crossover trial
-
Engelsen J, Nielsen J D., Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomized, double blind, placebo-crossover trial. Thromb Haemost 2002 87 1075-1076
-
(2002)
Thromb Haemost
, vol.87
, pp. 1075-1076
-
-
Engelsen, J.1
Nielsen, J.D.2
Winther, K.3
-
156
-
-
0142244568
-
Impact of Ginkgo biloba on the pharmacokinetics of digoxin
-
Mauro V F., Mauro L S., Kleshinski J F., Khuder S A., Wang Y, Erhardt P W. Impact of Ginkgo biloba on the pharmacokinetics of digoxin. Am J Ther 2003 10 247-251
-
(2003)
Am J Ther
, vol.10
, pp. 247-251
-
-
Mauro, V.F.1
Mauro, L.S.2
Kleshinski, J.F.3
Khuder, S.A.4
Wang, Y.5
Erhardt, P.W.6
-
157
-
-
0344464750
-
Multiple-dose administration of Ginkgo biloba did not affect cytochrome P-450 2D6 or 3A4 activity in normal volunteers
-
Markowitz J S., Donovan J L., DeVane L, Sipkes L, Chavin K D. Multiple-dose administration of Ginkgo biloba did not affect cytochrome P-450 2D6 or 3A4 activity in normal volunteers. J Clin Psychopharmacol 2003 23 576-581
-
(2003)
J Clin Psychopharmacol
, vol.23
, pp. 576-581
-
-
Markowitz, J.S.1
Donovan, J.L.2
Devane, L.3
Sipkes, L.4
Chavin, K.D.5
-
158
-
-
21644486138
-
Studies on interactions between functional foods or dietary supplements and medicines. IV. Effects of Ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in healthy volunteers
-
Yoshioka M, Ohnishi N, Koishi T, Obata Y, Nakagawa M, Matsumoto T, Tagagi K, Takara K, Ohkuni T, Yokoyama T, Kuroda K. Studies on interactions between functional foods or dietary supplements and medicines. IV. Effects of Ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in healthy volunteers. Biol Pharm Bull 2004 27 2006-2009
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 2006-2009
-
-
Yoshioka, M.1
Ohnishi, N.2
Koishi, T.3
Obata, Y.4
Nakagawa, M.5
Matsumoto, T.6
Tagagi, K.7
Takara, K.8
Ohkuni, T.9
Yokoyama, T.10
Kuroda, K.11
-
159
-
-
1942476104
-
The effects of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of donepezil
-
Yasui-Furukori N, Furukori H, Kaneda A, Kaneko S, Tateishi T. The effects of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of donepezil. J Clin Pharmacol 2004 44 538-542
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 538-542
-
-
Yasui-Furukori, N.1
Furukori, H.2
Kaneda, A.3
Kaneko, S.4
Tateishi, T.5
-
160
-
-
17144396657
-
Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects
-
Jiang X, Williams K M., Liauw W S., Ammit A J., Roufogalis B D., Duke C C., Day R O., McLachlan A J. Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2005 59 425-432
-
(2005)
Br J Clin Pharmacol
, vol.59
, pp. 425-432
-
-
Jiang, X.1
Williams, K.M.2
Liauw, W.S.3
Ammit, A.J.4
Roufogalis, B.D.5
Duke, C.C.6
Day, R.O.7
McLachlan, A.J.8
-
161
-
-
26044458501
-
Effect of Ginkgo biloba extract on plasma steroid concentrations in healthy volunteers: A pilot study
-
Markowitz J S., DeVane C L., Lewis J G., Chavin K D., Wang J-S, Donovan J L. Effect of Ginkgo biloba extract on plasma steroid concentrations in healthy volunteers: a pilot study. Pharmacotherapy 2005 25 1337-1340
-
(2005)
Pharmacotherapy
, vol.25
, pp. 1337-1340
-
-
Markowitz, J.S.1
Devane, C.L.2
Lewis, J.G.3
Chavin, K.D.4
Wang, J.-S.5
Donovan, J.L.6
-
162
-
-
33846970912
-
Pharmacodynamic interaction studies of Ginkgo biloba with cilostazol and clopidogrel in healthy human subjects
-
Aruna D, Naidu M U. R. Pharmacodynamic interaction studies of Ginkgo biloba with cilostazol and clopidogrel in healthy human subjects. Br J Clin Pharmacol 2006 63 333-338
-
(2006)
Br J Clin Pharmacol
, vol.63
, pp. 333-338
-
-
Aruna, D.1
Naidu, M.U.R.2
-
163
-
-
31544472883
-
Ginkgo biloba: Evaluation of CYP2C9 drug interactions in vitro and in vivo
-
Mohutsky M A., Anderson G D., Miller J W., Elmer G W. Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivo. Am J Ther 2006 13 24-31
-
(2006)
Am J Ther
, vol.13
, pp. 24-31
-
-
Mohutsky, M.A.1
Anderson, G.D.2
Miller, J.W.3
Elmer, G.W.4
-
164
-
-
31444439243
-
Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate
-
Greenblatt D J., von Moltke L L., Luo Y, Perloff E S., Horan K A., Bruce A, Reynolds R C., Harmatz J S., Avula B, Khan I A., Goldman P. Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate. J Clin Pharmacol 2006 46 214-221
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 214-221
-
-
Greenblatt, D.J.1
Von Moltke, L.L.2
Luo, Y.3
Perloff, E.S.4
Horan, K.A.5
Bruce, A.6
Reynolds, R.C.7
Harmatz, J.S.8
Avula, B.9
Khan, I.A.10
Goldman, P.11
-
165
-
-
33745232469
-
The effects of ergoloid mesylates and Ginkgo biloba on the pharmacokinetics of ticlopidine
-
Lu W-J, Huang J, Lai M-L. The effects of ergoloid mesylates and Ginkgo biloba on the pharmacokinetics of ticlopidine. J Clin Pharmacol 2006 46 628-634
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 628-634
-
-
Lu, W.-J.1
Huang, J.2
Lai, M.-L.3
-
166
-
-
33749838677
-
Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers
-
Uchida S, Yamada H, Li X D., Maruyama S, Ohmori Y, Oki T, Watanabe H, Umegaki K, Ohashi K, Yamada S. Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers. J Clin Pharmacol 2006 46 1290-1298
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 1290-1298
-
-
Uchida, S.1
Yamada, H.2
Li, X.D.3
Maruyama, S.4
Ohmori, Y.5
Oki, T.6
Watanabe, H.7
Umegaki, K.8
Ohashi, K.9
Yamada, S.10
-
167
-
-
33745128738
-
Does Ginkgo biloba special extract EGb 761 provide additional effects on coagulation and bleeding when added to acetylsalicylic acid 500 mg daily
-
Wolf H R. D. Does Ginkgo biloba special extract EGb 761 provide additional effects on coagulation and bleeding when added to acetylsalicylic acid 500 mg daily? Drugs R D 2006 7 163-172
-
(2006)
Drugs R D
, vol.7
, pp. 163-172
-
-
Wolf, H.R.D.1
-
168
-
-
33749873660
-
Investigation of the effects of herbal medicines on warfarin response in healthy subjects: A population pharmacokinetic-pharmacodynamic modeling approach
-
Jiang X, Blair E Y. L., McLachlan A J. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006 46 1370-1378
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 1370-1378
-
-
Jiang, X.1
Blair, E.Y.L.2
McLachlan, A.J.3
-
169
-
-
33746092899
-
The effect of the ingestion of Ginkgo biloba extract (EGb 761) on the pharmacokinetics of metformin in non-diabetic and type 2 diabetic subjects - A double blind placebo-controlled, crossover study
-
Kudolo G B., Wang W, Javors M, Blodgett J. The effect of the ingestion of Ginkgo biloba extract (EGb 761) on the pharmacokinetics of metformin in non-diabetic and type 2 diabetic subjects - A double blind placebo-controlled, crossover study. Clin Nutr 2006 25 606-616
-
(2006)
Clin Nutr
, vol.25
, pp. 606-616
-
-
Kudolo, G.B.1
Wang, W.2
Javors, M.3
Blodgett, J.4
-
170
-
-
39749122043
-
Effect of Ginkgo biloba extract on lopinavir, midazolam, and fexofenadine pharmacokinetics in healthy subjects
-
Robertson S M., Davey R T., Voell J, Formentini E, Alfaro R M., Penzak S R. Effect of Ginkgo biloba extract on lopinavir, midazolam, and fexofenadine pharmacokinetics in healthy subjects. Curr Med Res Opin 2008 24 591-599
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 591-599
-
-
Robertson, S.M.1
Davey, R.T.2
Voell, J.3
Formentini, E.4
Alfaro, R.M.5
Penzak, S.R.6
-
171
-
-
65849263344
-
Lack of effect of Ginkgo biloba on voriconazole pharmacokinetics in Chinese volunteers identified as CYP2C19 poor and extensive metabolizers
-
Lei H P., Wang G, Wang L S., Ou-yang D, Chen H, Zhang W, Tan Z-R, Fan L, He Y-J, Zhou H-H. Lack of effect of Ginkgo biloba on voriconazole pharmacokinetics in Chinese volunteers identified as CYP2C19 poor and extensive metabolizers. Ann Pharmacother 2009 43 726-731
-
(2009)
Ann Pharmacother
, vol.43
, pp. 726-731
-
-
Lei, H.P.1
Wang, G.2
Wang, L.S.3
Ou-Yang, D.4
Chen, H.5
Zhang, W.6
Tan, Z.-R.7
Fan, L.8
He, Y.-J.9
Zhou, H.-H.10
-
172
-
-
66149157856
-
Effect of Schisandra chinensis extract and Ginkgo biloba extract on the pharmacokinetics of talinolol in healthy volunteers
-
Fan L, Mao X-Q, Tao G Y., Wang G, Jiang F, Chen Y, Li Q, Zhang W, Lei H-P, Hu D L., Huang Y-F, Wang D, Zhou H-H. Effect of Schisandra chinensis extract and Ginkgo biloba extract on the pharmacokinetics of talinolol in healthy volunteers. Xenobiotica 2009 39 249-254
-
(2009)
Xenobiotica
, vol.39
, pp. 249-254
-
-
Fan, L.1
Mao, X.-Q.2
Tao, G.Y.3
Wang, G.4
Jiang, F.5
Chen, Y.6
Li, Q.7
Zhang, W.8
Lei, H.-P.9
Hu, D.L.10
Huang, Y.-F.11
Wang, D.12
Zhou, H.-H.13
-
173
-
-
65749091812
-
Effects of Ginkgo biloba extract ingestion on the pharmcokinetics of talinolol in healthy Chinese volunteers
-
Fan L, Tao G-Y, Wang G, Chen Y, Zhang W, He Y-J, Li Q, Lei H-P, Jiang F, Hu D-L, Huang Y-F, Zhou H-H. Effects of Ginkgo biloba extract ingestion on the pharmcokinetics of talinolol in healthy Chinese volunteers. Ann Pharmacother 2009 43 944-949
-
(2009)
Ann Pharmacother
, vol.43
, pp. 944-949
-
-
Fan, L.1
Tao, G.-Y.2
Wang, G.3
Chen, Y.4
Zhang, W.5
He, Y.-J.6
Li, Q.7
Lei, H.-P.8
Jiang, F.9
Hu, D.-L.10
Huang, Y.-F.11
Zhou, H.-H.12
-
174
-
-
68449095081
-
Effects of Ginkgo biloba extract on the pharmacokinetics of bupropion in healthy volunteers
-
Lei H-P, Ji W, Lin J, Chen H, Tan Z-R, Hu D-L, Liu L-J, Zhou H-H. Effects of Ginkgo biloba extract on the pharmacokinetics of bupropion in healthy volunteers. Br J Clin Pharmacol 2009 68 201-206
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 201-206
-
-
Lei, H.-P.1
Ji, W.2
Lin, J.3
Chen, H.4
Tan, Z.-R.5
Hu, D.-L.6
Liu, L.-J.7
Zhou, H.-H.8
-
175
-
-
77954466612
-
Effects of Ginkgo biloba extracts on diazepam metabolism: A pharmacokinetic study in healthy Chinese male subjects
-
Zuo X-C, Zhang B-K, Jia S-J, Liu S-K, Zhou L-Y, Li J, Zhang J, Dai L-L, Chen B-M, Yang G-P, Yuan H. Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects. Eur J Clin Pharmacol 2010 66 503-509
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 503-509
-
-
Zuo, X.-C.1
Zhang, B.-K.2
Jia, S.-J.3
Liu, S.-K.4
Zhou, L.-Y.5
Li, J.6
Zhang, J.7
Dai, L.-L.8
Chen, B.-M.9
Yang, G.-P.10
Yuan, H.11
-
176
-
-
77649178117
-
Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: An open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers
-
Kim B-H, Kim K-P, Lim K S., Kim J-R, Yoon S H., Cho J-Y, Lee Y-O, Lee K-H, Jang I-J, Shin S-G, Yu K-S. Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers. Clin Ther 2010 32 380-390
-
(2010)
Clin Ther
, vol.32
, pp. 380-390
-
-
Kim, B.-H.1
Kim, K.-P.2
Lim, K.S.3
Kim, J.-R.4
Yoon, S.H.5
Cho, J.-Y.6
Lee, Y.-O.7
Lee, K.-H.8
Jang, I.-J.9
Shin, S.-G.10
Yu, K.-S.11
-
178
-
-
33846577441
-
Drug interaction studies: Study design, data analysis, and implications for dosing and labeling
-
Huang S M., Temple R, Throckmorton D C., Lesko L J. Drug interaction studies: study design, data analysis, and implications for dosing and labeling. Clin Pharmacol Ther 2007 81 298-304
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 298-304
-
-
Huang, S.M.1
Temple, R.2
Throckmorton, D.C.3
Lesko, L.J.4
-
179
-
-
84455163151
-
Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and preganane X receptor
-
Lau A J., Yang G, Rajaraman, Baucom C C., Chang T K. H. Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and preganane X receptor. Drug Metab Dispos 2012 40 178-186
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 178-186
-
-
Lau, A.J.1
Yang, G.2
Rajaraman3
Baucom, C.C.4
Chang, T.K.H.5
-
180
-
-
0034961776
-
Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts
-
Mauri P, Simonetti P, Gardana C, Minoggio M, Morazzoni P, Bombardelli E, Pietta P. Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts. Rapid Commun Mass Spectrom 2001 15 929-934
-
(2001)
Rapid Commun Mass Spectrom
, vol.15
, pp. 929-934
-
-
Mauri, P.1
Simonetti, P.2
Gardana, C.3
Minoggio, M.4
Morazzoni, P.5
Bombardelli, E.6
Pietta, P.7
-
181
-
-
0042326246
-
Pharmacokinetics of Ginkgo biloba extracts
-
Biber A. Pharmacokinetics of Ginkgo biloba extracts. Pharmacopsychiatry 2003 36 S32-S37
-
(2003)
Pharmacopsychiatry
, vol.36
-
-
Biber, A.1
-
182
-
-
77349104616
-
Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans
-
Woelkart K, Feizlmayr E, Dittrich P, Beubler E, Pinl F, Suter A, Bauer R. Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans. Phytother Res 2010 24 445-450
-
(2010)
Phytother Res
, vol.24
, pp. 445-450
-
-
Woelkart, K.1
Feizlmayr, E.2
Dittrich, P.3
Beubler, E.4
Pinl, F.5
Suter, A.6
Bauer, R.7
-
183
-
-
0036231404
-
Pharmaceutical quality of different Ginkgo biloba brands
-
Kressmann S, Mller W E., Blume H H. Pharmaceutical quality of different Ginkgo biloba brands. J Pharm Pharmacol 2002 54 661-669
-
(2002)
J Pharm Pharmacol
, vol.54
, pp. 661-669
-
-
Kressmann, S.1
Mller, W.E.2
Blume, H.H.3
-
184
-
-
0036849186
-
Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations
-
Kressmann S, Biber A, Wonnemann M, Schug B, Blume H H., Mller W E. Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations. J Pharm Pharmacol 2002 54 1507-1514
-
(2002)
J Pharm Pharmacol
, vol.54
, pp. 1507-1514
-
-
Kressmann, S.1
Biber, A.2
Wonnemann, M.3
Schug, B.4
Blume, H.H.5
Mller, W.E.6
-
185
-
-
77951087366
-
Intestinal and blood-brain barrier permeability of ginkgolides and bilobalide: In vitro and in vivo approaches
-
Madgula V L., Avula B, Yu Y B., Tchantchou F, Fisher S, Luo Y, Khan I A., Khan S I. Intestinal and blood-brain barrier permeability of ginkgolides and bilobalide: in vitro and in vivo approaches. Planta Med 2010 76 599-606
-
(2010)
Planta Med
, vol.76
, pp. 599-606
-
-
Madgula, V.L.1
Avula, B.2
Yu, Y.B.3
Tchantchou, F.4
Fisher, S.5
Luo, Y.6
Khan, I.A.7
Khan, S.I.8
-
186
-
-
70349408655
-
Current evaluation of the millennium phytomedicine - Ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine
-
Jia L, Zhao Y, Liang X-J. Current evaluation of the millennium phytomedicine - ginseng (II): collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine. Curr Med Chem 2009 16 2924-2942
-
(2009)
Curr Med Chem
, vol.16
, pp. 2924-2942
-
-
Jia, L.1
Zhao, Y.2
Liang, X.-J.3
-
187
-
-
0032830802
-
The efficacy of ginseng. A systematic review of randomized clinical trials
-
Vogler B K., Pittler M H., Ernst E. The efficacy of ginseng. A systematic review of randomized clinical trials. Eur J Clin Pharmacol 1999 55 567-575
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 567-575
-
-
Vogler, B.K.1
Pittler, M.H.2
Ernst, E.3
-
188
-
-
32344451301
-
Systematic review of the effects of ginseng on cardiovascular risk factors
-
Buettner C, Yeh G Y., Phillips R S., Mittleman M A., Kaptchuk T J. Systematic review of the effects of ginseng on cardiovascular risk factors. Ann Pharmacother 2005 39 83-95
-
(2005)
Ann Pharmacother
, vol.39
, pp. 83-95
-
-
Buettner, C.1
Yeh, G.Y.2
Phillips, R.S.3
Mittleman, M.A.4
Kaptchuk, T.J.5
-
189
-
-
77955575222
-
Ginseng on hyperglycemia: Effects and mechanisms
-
Luo J Z., Luo L. Ginseng on hyperglycemia: effects and mechanisms. eCAM 2009 6 423-427
-
(2009)
ECAM
, vol.6
, pp. 423-427
-
-
Luo, J.Z.1
Luo, L.2
-
190
-
-
50349101675
-
Ginsenosides: Chemistry, biosynthesis, analysis, and potential health effects
-
Christensen L P. Ginsenosides: chemistry, biosynthesis, analysis, and potential health effects. Adv Food Nutr Res 2008 55 1-99
-
(2008)
Adv Food Nutr Res
, vol.55
, pp. 1-99
-
-
Christensen, L.P.1
-
191
-
-
51349086818
-
Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium
-
Chen C, Choiu W, Zhang J. Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium. Acta Pharmacol Sin 2008 29 1103-1108
-
(2008)
Acta Pharmacol Sin
, vol.29
, pp. 1103-1108
-
-
Chen, C.1
Choiu, W.2
Zhang, J.3
-
192
-
-
0042526129
-
Degradation of ginsenosides on humans after oral administration
-
Tawab M A., Bahr U, Karas M, Wurglics M, Schubert-Zsilavecz M. Degradation of ginsenosides on humans after oral administration. Drug Metab Dispos 2003 31 1065-1071
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1065-1071
-
-
Tawab, M.A.1
Bahr, U.2
Karas, M.3
Wurglics, M.4
Schubert-Zsilavecz, M.5
-
193
-
-
6944253961
-
Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants
-
Bae E-A, Han M J., Kim E-J, Kim D-H. Transformation of ginseng saponins to ginsenoside Rh2 by acids and human intestinal bacteria and biological activities of their transformants. Arch Pharm Res 2004 27 61-67
-
(2004)
Arch Pharm Res
, vol.27
, pp. 61-67
-
-
Bae, E.-A.1
Han, M.J.2
Kim, E.-J.3
Kim, D.-H.4
-
194
-
-
59849098283
-
Studies on absorption, distribution and metabolism of ginseng in humans after oral administration
-
Lee J, Lee E, Kim D, Lee J, Yoo J, Koh B. Studies on absorption, distribution and metabolism of ginseng in humans after oral administration. J Ethnopharmacol 2009 122 143-148
-
(2009)
J Ethnopharmacol
, vol.122
, pp. 143-148
-
-
Lee, J.1
Lee, E.2
Kim, D.3
Lee, J.4
Yoo, J.5
Koh, B.6
-
196
-
-
3142621044
-
Proof of the mysterious efficacy of ginseng: Basic and clinical trials: Metabolic activation of ginsenoside; Deglycosylation by intestinal bacteria and esterification with fatty acid
-
Hasegawa H. Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside; deglycosylation by intestinal bacteria and esterification with fatty acid. J Pharmacol Sci 2004 95 153-157
-
(2004)
J Pharmacol Sci
, vol.95
, pp. 153-157
-
-
Hasegawa, H.1
-
197
-
-
33645214063
-
Difference in oral absorption of ginsenoside Rg1 between in vitro and in vivo models
-
Han M, Fang X. Difference in oral absorption of ginsenoside Rg1 between in vitro and in vivo models. Acta Pharmacol Sin 2006 27 499-505
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 499-505
-
-
Han, M.1
Fang, X.2
-
198
-
-
19444370594
-
Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells
-
Xie H-T, Wang G-J, Chen M, Jiang X, Li H, Lv H, Huang C-R, Wang R, Roberts M. Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells. Biol Pharm Bull 2005 28 383-386
-
(2005)
Biol Pharm Bull
, vol.28
, pp. 383-386
-
-
Xie, H.-T.1
Wang, G.-J.2
Chen, M.3
Jiang, X.4
Li, H.5
Lv, H.6
Huang, C.-R.7
Wang, R.8
Roberts, M.9
-
199
-
-
77955607007
-
Intestinal absorption mechanisms of ginsenoside Rh2: Stereoselectivity and involvement of ABC transporters
-
Gu Y, Wang G-J, Wu X-L, Zheng Y-T, Zhang J-W, Ai H, Sun J-G, Jia Y-W. Intestinal absorption mechanisms of ginsenoside Rh2: stereoselectivity and involvement of ABC transporters. Xenobiotica 2010 40 602-612
-
(2010)
Xenobiotica
, vol.40
, pp. 602-612
-
-
Gu, Y.1
Wang, G.-J.2
Wu, X.-L.3
Zheng, Y.-T.4
Zhang, J.-W.5
Ai, H.6
Sun, J.-G.7
Jia, Y.-W.8
-
200
-
-
2942517295
-
Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity
-
Henderson G L., Harkey M R., Gershwin M E., Hackman R M., Stern J S., Stresser D M. Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity. Pharmacol Lett 1999 65 209-214
-
(1999)
Pharmacol Lett
, vol.65
, pp. 209-214
-
-
Henderson, G.L.1
Harkey, M.R.2
Gershwin, M.E.3
Hackman, R.M.4
Stern, J.S.5
Stresser, D.M.6
-
201
-
-
0036206368
-
In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1
-
Chang T K. H., Chen J, Benetton S A. In vitro effect of standardized ginseng extracts and individual ginsenosides on the catalytic activity of human CYP1A1, CYP1A2, and CYP1B1. Drug Metab Dispos 2002 30 378-384
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 378-384
-
-
Chang, T.K.H.1
Chen, J.2
Benetton, S.A.3
-
202
-
-
0037212768
-
3
-
3. Biochem Pharmacol 2003 65 75-82
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 75-82
-
-
Kim, S.-W.1
Kwon, H.2
Chi, D.-W.3
Shim, J.-H.4
Park, J.-D.5
Lee, Y.-H.6
Pyo, S.7
Rhee, D.-K.8
-
203
-
-
33744799726
-
Ginsenoside metabolites, rather than naturally occurring ginsenosides, lead to inhibition of human cytochrome P450 enzymes
-
Liu Y, Zhang J-W, Li W, Ma H, Sun J, Deng M-C, Yang L. Ginsenoside metabolites, rather than naturally occurring ginsenosides, lead to inhibition of human cytochrome P450 enzymes. Toxicol Sci 2006 91 356-364
-
(2006)
Toxicol Sci
, vol.91
, pp. 356-364
-
-
Liu, Y.1
Zhang, J.-W.2
Li, W.3
Ma, H.4
Sun, J.5
Deng, M.-C.6
Yang, L.7
-
204
-
-
33644553478
-
Influence of ginsenoside Rh1 and F1 on human cytochrome p 450 enzymes
-
Liu Y, Ma H, Zhang J W., Deng M C., Yang L. Influence of ginsenoside Rh1 and F1 on human cytochrome p 450 enzymes. Planta Med 2006 72 126-131
-
(2006)
Planta Med
, vol.72
, pp. 126-131
-
-
Liu, Y.1
Ma, H.2
Zhang, J.W.3
Deng, M.C.4
Yang, L.5
-
205
-
-
33744548409
-
Metabolites of ginsenosides as novel BCRP inhibitors
-
Jin J, Shahi S, Kang H K., van Veen H W., Fan T-P. Metabolites of ginsenosides as novel BCRP inhibitors. Biochem Biophys Res Commun 2006 345 1308-1314
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1308-1314
-
-
Jin, J.1
Shahi, S.2
Kang, H.K.3
Van Veen, H.W.4
Fan, T.-P.5
-
206
-
-
35349005744
-
Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells
-
Kitagawa S, Takahashi T, Nabekura T, Tachikawa E, Hasegawa H. Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells. Biol Pharm Bull 2007 30 1979-1981
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 1979-1981
-
-
Kitagawa, S.1
Takahashi, T.2
Nabekura, T.3
Tachikawa, E.4
Hasegawa, H.5
-
207
-
-
49949113587
-
Structure-activity relationship and substrate-dependent phenomena in effects of ginsenosides on activities of drug-metabolizing P450 enzymes
-
Hao M, Zhao Y, Chen P, Huang H, Liu H, Jiang H, Zhang R, Wang H. Structure-activity relationship and substrate-dependent phenomena in effects of ginsenosides on activities of drug-metabolizing P450 enzymes. PLoS One 2008 3 e2697
-
(2008)
PLoS One
, vol.3
-
-
Hao, M.1
Zhao, Y.2
Chen, P.3
Huang, H.4
Liu, H.5
Jiang, H.6
Zhang, R.7
Wang, H.8
-
208
-
-
76749169561
-
Increased ubiquination of multidrug resistance 1 by ginsenoside Rd
-
Pokharel Y R., Kim N D., Han H K., Oh W K., Kang K W. Increased ubiquination of multidrug resistance 1 by ginsenoside Rd. Nutr Cancer 2010 62 252-259
-
(2010)
Nutr Cancer
, vol.62
, pp. 252-259
-
-
Pokharel, Y.R.1
Kim, N.D.2
Han, H.K.3
Oh, W.K.4
Kang, K.W.5
-
209
-
-
0023472232
-
Efects of Panax ginseng extract on the benzo(a)pyrene metabolizing enzyme system
-
Lee F C., Park J K., Ko J H., Lee J S., Kim K Y., Kim E K. Efects of Panax ginseng extract on the benzo(a)pyrene metabolizing enzyme system. Drug Chem Toxicol 1987 10 227-236
-
(1987)
Drug Chem Toxicol
, vol.10
, pp. 227-236
-
-
Lee, F.C.1
Park, J.K.2
Ko, J.H.3
Lee, J.S.4
Kim, K.Y.5
Kim, E.K.6
-
210
-
-
0027446436
-
Effect of ginseng on plasma levels of ethanol in the rat
-
Lee Y J., Pantuck C B., Pantuck E J. Effect of ginseng on plasma levels of ethanol in the rat. Planta Med 1993 59 17-19
-
(1993)
Planta Med
, vol.59
, pp. 17-19
-
-
Lee, Y.J.1
Pantuck, C.B.2
Pantuck, E.J.3
-
211
-
-
34347346161
-
The potent protective effect of wild ginseng (Panax ginseng C.A. Meyer) against benzo[alpha]pyrene-induced toxicity through metabolic regulation of CYP1A1 and GSTs
-
Gum S I., Jo S J., Ahn S H., Kim S G., Kim J T., Shin H M., Cho M K. The potent protective effect of wild ginseng (Panax ginseng C.A. Meyer) against benzo[alpha]pyrene-induced toxicity through metabolic regulation of CYP1A1 and GSTs. J Ethnopharmacol 2007 112 568-576
-
(2007)
J Ethnopharmacol
, vol.112
, pp. 568-576
-
-
Gum, S.I.1
Jo, S.J.2
Ahn, S.H.3
Kim, S.G.4
Kim, J.T.5
Shin, H.M.6
Cho, M.K.7
-
212
-
-
69049101305
-
Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo
-
Zhang R, Jie J, Zhou Y, Cao Z, Li W. Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo. Am J Chin Med 2009 37 657-667
-
(2009)
Am J Chin Med
, vol.37
, pp. 657-667
-
-
Zhang, R.1
Jie, J.2
Zhou, Y.3
Cao, Z.4
Li, W.5
-
213
-
-
0032997935
-
Possible influences of ginseng on the pharmacokinetics and pharmacodynamics of warfarin in rats
-
Zhu M, Chan K W., Ng L S., Chang Q, Chang S, Li R C. Possible influences of ginseng on the pharmacokinetics and pharmacodynamics of warfarin in rats. J Pharm Pharmacol 1999 51 175-180
-
(1999)
J Pharm Pharmacol
, vol.51
, pp. 175-180
-
-
Zhu, M.1
Chan, K.W.2
Ng, L.S.3
Chang, Q.4
Chang, S.5
Li, R.C.6
-
214
-
-
11144261054
-
Lack of evidence for induction of CYP2B1, CYP3A23, and CYP1A2 gene expression by Panax ginseng and Panax quinquefolius extracts in adult rats and primary cultures of rat hepatocytes
-
Yu C-T, Chen J, Teng X W., Tong V, Chang T K. H. Lack of evidence for induction of CYP2B1, CYP3A23, and CYP1A2 gene expression by Panax ginseng and Panax quinquefolius extracts in adult rats and primary cultures of rat hepatocytes. Drug Metab Dispos 2005 33 19-22
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 19-22
-
-
Yu, C.-T.1
Chen, J.2
Teng, X.W.3
Tong, V.4
Chang, T.K.H.5
-
216
-
-
2342563067
-
Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects
-
Jiang X, Williams K M., Liauw W S., Ammit A J., Roufogalis B D., Duke C C., Day R O., McLachlan A J. Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2004 57 592-599
-
(2004)
Br J Clin Pharmacol
, vol.57
, pp. 592-599
-
-
Jiang, X.1
Williams, K.M.2
Liauw, W.S.3
Ammit, A.J.4
Roufogalis, B.D.5
Duke, C.C.6
Day, R.O.7
McLachlan, A.J.8
-
217
-
-
41849106806
-
Possible differential induction of phase 2 enzyme and antioxidant pathways by American ginseng, Panax quinquefolius
-
Lee L S., Wise S D., Chan C, Parsons T L., Flexner C, Lietman P S. Possible differential induction of phase 2 enzyme and antioxidant pathways by American ginseng, Panax quinquefolius. J Clin Pharmacol 2008 48 599-609
-
(2008)
J Clin Pharmacol
, vol.48
, pp. 599-609
-
-
Lee, L.S.1
Wise, S.D.2
Chan, C.3
Parsons, T.L.4
Flexner, C.5
Lietman, P.S.6
-
218
-
-
49249126098
-
Interaction between warfarin and Panax ginseng in ischemic stroke patients
-
Lee S-H, Ahn Y-M, Ahn S-Y, Doo H-K, Lee B-C. Interaction between warfarin and Panax ginseng in ischemic stroke patients. J Altern Complement Med 2008 14 715-721
-
(2008)
J Altern Complement Med
, vol.14
, pp. 715-721
-
-
Lee, S.-H.1
Ahn, Y.-M.2
Ahn, S.-Y.3
Doo, H.-K.4
Lee, B.-C.5
-
219
-
-
52449087498
-
Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir
-
Andrade A S. A., Hendrix C, Parsons T L., Caballero B, Yuan C-S, Flexner C W., Dobs A S., Brown T T. Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir. BMC Complement Altern Med 2008 8 50
-
(2008)
BMC Complement Altern Med
, vol.8
, pp. 50
-
-
Andrade, A.S.A.1
Hendrix, C.2
Parsons, T.L.3
Caballero, B.4
Yuan, C.-S.5
Flexner, C.W.6
Dobs, A.S.7
Brown, T.T.8
-
221
-
-
3042737049
-
American ginseng reduces warfarin's effect in healthy patients: A randomized, controlled trial
-
Yuan C-S, Wei G, Dey L, Karrison T, Nahlik L, Maleckar S, Kasza K, Ang-Lee M, Moss J. American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled trial. Ann Intern Med 2004 141 23-27
-
(2004)
Ann Intern Med
, vol.141
, pp. 23-27
-
-
Yuan, C.-S.1
Wei, G.2
Dey, L.3
Karrison, T.4
Nahlik, L.5
Maleckar, S.6
Kasza, K.7
Ang-Lee, M.8
Moss, J.9
-
222
-
-
33749873660
-
Investigation of the effects of herbal medicines on warfarin response in healthy subjects: A population pharmacokinetic-pharmacodynamic modeling approach
-
Jiang X, Blair E Y. L., McLachlan A J. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006 46 1370-1378
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 1370-1378
-
-
Jiang, X.1
Blair, E.Y.L.2
McLachlan, A.J.3
-
223
-
-
0031002860
-
Probable interaction between warfarin and ginseng
-
Janetzky K, Morreale A P. Probable interaction between warfarin and ginseng. Am J Health Syst Pharm 1997 54 692-693
-
(1997)
Am J Health Syst Pharm
, vol.54
, pp. 692-693
-
-
Janetzky, K.1
Morreale, A.P.2
-
224
-
-
0037278438
-
Thrombosis of a prosthetic aortic valve disclosing a hazardous interaction between warfarin and a commercial ginseng product
-
Rosado M F. Thrombosis of a prosthetic aortic valve disclosing a hazardous interaction between warfarin and a commercial ginseng product. Cardiology 2003 99 111
-
(2003)
Cardiology
, vol.99
, pp. 111
-
-
Rosado, M.F.1
-
226
-
-
33644851228
-
Altered CYP expression and function in response to dietary factors: Potential roles in disease pathogenesis
-
Murray M. Altered CYP expression and function in response to dietary factors: potential roles in disease pathogenesis. Curr Drug Metab 2006 7 67-81
-
(2006)
Curr Drug Metab
, vol.7
, pp. 67-81
-
-
Murray, M.1
-
227
-
-
0034232506
-
Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation
-
Murray M. Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation. Curr Drug Metab 2000 1 67-84
-
(2000)
Curr Drug Metab
, vol.1
, pp. 67-84
-
-
Murray, M.1
-
228
-
-
0016238393
-
Interaction of methylenedioxyphenyl (1,3-benzodioxole) compounds with enzymes and their effects on mammals
-
Hodgson E, Philpot R M. Interaction of methylenedioxyphenyl (1,3-benzodioxole) compounds with enzymes and their effects on mammals. Drug Metab Rev 1974 3 231-301
-
(1974)
Drug Metab Rev
, vol.3
, pp. 231-301
-
-
Hodgson, E.1
Philpot, R.M.2
-
229
-
-
0027264897
-
Regulation of cytochrome P-450 isozymes by methylenedioxyphenyl compounds
-
Adams N H., Levi P E., Hodgson E. Regulation of cytochrome P-450 isozymes by methylenedioxyphenyl compounds. Chem Biol Interact 1993 86 255-274
-
(1993)
Chem Biol Interact
, vol.86
, pp. 255-274
-
-
Adams, N.H.1
Levi, P.E.2
Hodgson, E.3
-
230
-
-
0033377106
-
Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds
-
Nakajima M, Suzuki M, Yamaji R, Takashina H, Shimada N, Yamazaki H, Yoko T. Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds. Xenobiotica 1999 29 1191-1202
-
(1999)
Xenobiotica
, vol.29
, pp. 1191-1202
-
-
Nakajima, M.1
Suzuki, M.2
Yamaji, R.3
Takashina, H.4
Shimada, N.5
Yamazaki, H.6
Yoko, T.7
-
231
-
-
0142181023
-
Human cytochrome P450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components
-
Chatterjee P, Franklin M R. Human cytochrome P450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components. Drug Metab Dispos 2003 31 1391-1397
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1391-1397
-
-
Chatterjee, P.1
Franklin, M.R.2
-
232
-
-
37548998985
-
Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo
-
Gurley B J., Swain A, Hubbard M A., Hartsfield F, Thaden J, Williams D K., Gentry W B., Tong Y. Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo. Clin Pharmacol Ther 2008 83 61-69
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 61-69
-
-
Gurley, B.J.1
Swain, A.2
Hubbard, M.A.3
Hartsfield, F.4
Thaden, J.5
Williams, D.K.6
Gentry, W.B.7
Tong, Y.8
-
234
-
-
26244451259
-
Effects of berberine on the blood concentration of cyclosporine A in renal transplanted recipients: Clinical and pharmacokinetic study
-
Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporine A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005 61 567-572
-
(2005)
Eur J Clin Pharmacol
, vol.61
, pp. 567-572
-
-
Wu, X.1
Li, Q.2
Xin, H.3
Yu, A.4
Zhong, M.5
-
235
-
-
33645337094
-
The effects of berberine on the pharmacokinetics of ciclosporin A in healthy volunteers
-
Xin H-W, Wu X-C, Li Q, Yu A-R, Zhong M-Y, Liu Y-Y. The effects of berberine on the pharmacokinetics of ciclosporin A in healthy volunteers. Methods Find Exp Clin Pharmacol 2006 28 25-29
-
(2006)
Methods Find Exp Clin Pharmacol
, vol.28
, pp. 25-29
-
-
Xin, H.-W.1
Wu, X.-C.2
Li, Q.3
Yu, A.-R.4
Zhong, M.-Y.5
Liu, Y.-Y.6
-
236
-
-
0036797498
-
The involvement of P-glycoprotein in berberine absorption
-
Pan G Y., Wang G J., Liu X D., Fawcett J P., Xie Y Y. The involvement of P-glycoprotein in berberine absorption. Pharmacol Toxicol 2002 91 193-197
-
(2002)
Pharmacol Toxicol
, vol.91
, pp. 193-197
-
-
Pan, G.Y.1
Wang, G.J.2
Liu, X.D.3
Fawcett, J.P.4
Xie, Y.Y.5
-
237
-
-
1842589296
-
Hepatobiliary excretion of berberine
-
Tsai P L., Tsai T H. Hepatobiliary excretion of berberine. Drug Metab Dispos 2004 32 405-412
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 405-412
-
-
Tsai, P.L.1
Tsai, T.H.2
-
238
-
-
33846547591
-
Human MDR1 and MRP1 recognize berberine as their transport substrate
-
Shitan N, Tanaka M, Terai K, Ueda K, Yazaki K. Human MDR1 and MRP1 recognize berberine as their transport substrate. Biosci Biotechnol Biochem 2007 71 242-245
-
(2007)
Biosci Biotechnol Biochem
, vol.71
, pp. 242-245
-
-
Shitan, N.1
Tanaka, M.2
Terai, K.3
Ueda, K.4
Yazaki, K.5
-
239
-
-
38349168958
-
Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1)
-
Nies A T., Herrmann E, Brom M, Keppler D. Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1). Naunyn Schmiedebergs Arch Pharmacol 2008 376 449-461
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.376
, pp. 449-461
-
-
Nies, A.T.1
Herrmann, E.2
Brom, M.3
Keppler, D.4
-
240
-
-
70350437674
-
Effect of berberine on the pharmacokinetics of substrates of CYP3A and P-gp
-
Qiu W, Jiang X H., Liu C X., Ju Y, Jin J X. Effect of berberine on the pharmacokinetics of substrates of CYP3A and P-gp. Phytother Res 2009 23 1553-1558
-
(2009)
Phytother Res
, vol.23
, pp. 1553-1558
-
-
Qiu, W.1
Jiang, X.H.2
Liu, C.X.3
Ju, Y.4
Jin, J.X.5
-
241
-
-
33846431610
-
Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans
-
Gurley B J., Swain A, Barone G W., Williams D K., Breen P, Yates C R., Stuart L B., Hubbard M A., Tong Y, Cheboyina S. Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans. Drug Metab Dispos 2007 35 240-245
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 240-245
-
-
Gurley, B.J.1
Swain, A.2
Barone, G.W.3
Williams, D.K.4
Breen, P.5
Yates, C.R.6
Stuart, L.B.7
Hubbard, M.A.8
Tong, Y.9
Cheboyina, S.10
-
242
-
-
85028114677
-
-
University of Arkansas for Medical Sciences, Little Rock. Personal communication. October 9
-
Gurley B J. University of Arkansas for Medical Sciences, Little Rock. Personal communication. October 9, 2011.
-
(2011)
-
-
Gurley, B.J.1
-
243
-
-
84920078598
-
Clinical pharmacokinetics and metabolism of berberine and hydrastine following an oral dose of goldenseal supplement
-
Gupta P K., Gurley B J., Barone G, Hendrickson H P. Clinical pharmacokinetics and metabolism of berberine and hydrastine following an oral dose of goldenseal supplement. Planta Med 2010 76 546
-
(2010)
Planta Med
, vol.76
, pp. 546
-
-
Gupta, P.K.1
Gurley, B.J.2
Barone, G.3
Hendrickson, H.P.4
-
244
-
-
21744457082
-
Safety review of kava (Piper methysticum) by the Natural Standard Research Collaboration
-
Ulbricht C, Basch E, Boon H, Ernst E, Hammerness P, Sollars D, Tsourounis C. Safety review of kava (Piper methysticum) by the Natural Standard Research Collaboration. Expert Opin Drug Saf 2005 4 779-794
-
(2005)
Expert Opin Drug Saf
, vol.4
, pp. 779-794
-
-
Ulbricht, C.1
Basch, E.2
Boon, H.3
Ernst, E.4
Hammerness, P.5
Sollars, D.6
Tsourounis, C.7
-
245
-
-
4143093675
-
Composition and biological activity of traditional and commercial kava extracts
-
Ct C S., Kor C, Cohen J, Auclair K. Composition and biological activity of traditional and commercial kava extracts. Biochem Biophys Res Commun 2004 322 147-152
-
(2004)
Biochem Biophys Res Commun
, vol.322
, pp. 147-152
-
-
Ct, C.S.1
Kor, C.2
Cohen, J.3
Auclair, K.4
-
246
-
-
4644223218
-
Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction
-
Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004 18 2273-2281
-
(2004)
Rapid Commun Mass Spectrom
, vol.18
, pp. 2273-2281
-
-
Unger, M.1
Frank, A.2
-
247
-
-
0036842023
-
Inhibition of human cytochrome P450 activities by kava extract and kava lactones
-
Mathews J M., Etheridge A S., Black S R. Inhibition of human cytochrome P450 activities by kava extract and kava lactones. Drug Metab Dispos 2002 30 1153-1157
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1153-1157
-
-
Mathews, J.M.1
Etheridge, A.S.2
Black, S.R.3
-
248
-
-
0036971231
-
Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (kava-kava)
-
Unger M, Holzgrabe U, Jacobsen W, Cummins C, Benet L Z. Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (kava-kava). Planta Med 2002 68 1055-1058
-
(2002)
Planta Med
, vol.68
, pp. 1055-1058
-
-
Unger, M.1
Holzgrabe, U.2
Jacobsen, W.3
Cummins, C.4
Benet, L.Z.5
-
249
-
-
2442706282
-
Effects of kava (kava-kava, awa, yaqona, Piper methysticum) on c-DNA-expressed cytochrome P450 enzymes and human cryopreserved hepatocytes
-
Zou L, Henderson G L., Harkey M R., Sakai Y, Li A. Effects of kava (kava-kava, awa, yaqona, Piper methysticum) on c-DNA-expressed cytochrome P450 enzymes and human cryopreserved hepatocytes. Phytomedicine 2004 11 285-294
-
(2004)
Phytomedicine
, vol.11
, pp. 285-294
-
-
Zou, L.1
Henderson, G.L.2
Harkey, M.R.3
Sakai, Y.4
Li, A.5
-
250
-
-
24944587145
-
Pharmacokinetics and disposition of the kavalactone kawain: Interaction with kava extract and kavalactones in vivo and in vitro
-
Mathews J M., Etheridge A S., Valentine J L., Black S R., Coleman D P., Patel P, So J, Burka L T. Pharmacokinetics and disposition of the kavalactone kawain: interaction with kava extract and kavalactones in vivo and in vitro. Drug Metab Dispos 2005 33 1555-1563
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1555-1563
-
-
Mathews, J.M.1
Etheridge, A.S.2
Valentine, J.L.3
Black, S.R.4
Coleman, D.P.5
Patel, P.6
So, J.7
Burka, L.T.8
-
251
-
-
27544501065
-
Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro
-
Weiss J, Sauer A, Frank A, Unger M. Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro. Drug Metab Dispos 2005 33 1580-1583
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1580-1583
-
-
Weiss, J.1
Sauer, A.2
Frank, A.3
Unger, M.4
-
252
-
-
0037403686
-
Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products
-
Raucy J L. Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products. Drug Metab Dispos 2003 31 533-539
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 533-539
-
-
Raucy, J.L.1
-
253
-
-
6944230909
-
Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23
-
Ma Y, Sachdeva K, Liu J, Ford M, Yang D, Khan I A., Chichester C O., Yan B. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos 2004 32 1317-1324
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1317-1324
-
-
Ma, Y.1
Sachdeva, K.2
Liu, J.3
Ford, M.4
Yang, D.5
Khan, I.A.6
Chichester, C.O.7
Yan, B.8
-
254
-
-
11144349691
-
High volume bioassays to assess CYP3A4-mediated drug interactions: Induction and inhibition in a single cell line
-
Yueh M-F, Kawahara M, Raucy J. High volume bioassays to assess CYP3A4-mediated drug interactions: induction and inhibition in a single cell line. Drug Metab Dispos 2005 33 38-48
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 38-48
-
-
Yueh, M.-F.1
Kawahara, M.2
Raucy, J.3
-
255
-
-
34347232391
-
Effects of kava alkaloid, pipermethystine, and kavalactones on oxidative stress and cytochrome P450 in F-344 rats
-
Lim S T. S., Dragull K, Tang C-S, Bittenbender H C., Efird J T., Nerurkar P V. Effects of kava alkaloid, pipermethystine, and kavalactones on oxidative stress and cytochrome P450 in F-344 rats. Toxicol Sci 2007 97 214-221
-
(2007)
Toxicol Sci
, vol.97
, pp. 214-221
-
-
Lim, S.T.S.1
Dragull, K.2
Tang, C.-S.3
Bittenbender, H.C.4
Efird, J.T.5
Nerurkar, P.V.6
-
256
-
-
33845346818
-
Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract
-
Clayton N P., Yoshizawa K, Kissling G E., Burka L T., Chan P-C, Nyska A. Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract. Exp Toxicol Path 2007 58 223-236
-
(2007)
Exp Toxicol Path
, vol.58
, pp. 223-236
-
-
Clayton, N.P.1
Yoshizawa, K.2
Kissling, G.E.3
Burka, L.T.4
Chan, P.-C.5
Nyska, A.6
-
257
-
-
55949103189
-
High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats
-
Yamazaki Y, Hashida H, Arita A, Hamaguchi K, Shimura F. High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats. Food Chem Toxicol 2008 46 3732-3738
-
(2008)
Food Chem Toxicol
, vol.46
, pp. 3732-3738
-
-
Yamazaki, Y.1
Hashida, H.2
Arita, A.3
Hamaguchi, K.4
Shimura, F.5
-
258
-
-
58149512737
-
Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract
-
Guo L, Li Q, Xia Q, Dial S, Chan P-C, Fu P. Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract. Food Chem Toxicol 2009 47 433-442
-
(2009)
Food Chem Toxicol
, vol.47
, pp. 433-442
-
-
Guo, L.1
Li, Q.2
Xia, Q.3
Dial, S.4
Chan, P.-C.5
Fu, P.6
-
259
-
-
85028107020
-
Traditional aqueous kava extracts inhibit cytochrome P450 1A2 in humans: Protective effect against environmental carcinogens
-
Russman S, Barguil Y, Cabalion P, Rentsch K, Wenk M. Traditional aqueous kava extracts inhibit cytochrome P450 1A2 in humans: protective effect against environmental carcinogens? Clin Pharmacol Ther 2005 77 451-454
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 451-454
-
-
Russman, S.1
Barguil, Y.2
Cabalion, P.3
Rentsch, K.4
Wenk, M.5
-
260
-
-
35948951161
-
Black pepper and its pungent principle-piperine: A review of diverse physiological effects
-
Srinivasan K. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Crit Rev Food Sci Nutr 2007 47 735-748
-
(2007)
Crit Rev Food Sci Nutr
, vol.47
, pp. 735-748
-
-
Srinivasan, K.1
-
261
-
-
0019453954
-
Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs
-
Atal C K., Zutshi U, Rao P G. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. J Ethnopharmacol 1981 4 229-232
-
(1981)
J Ethnopharmacol
, vol.4
, pp. 229-232
-
-
Atal, C.K.1
Zutshi, U.2
Rao, P.G.3
-
262
-
-
44349134660
-
Analysis by HPLC and LC/MS of pungent piperamides in commercial black, white, green, and red whole and ground peppercorns
-
Friedman M, Levin C E., Lee S-U, Lee J-S, Ohnisi-Kameyama M, Kozukue N. Analysis by HPLC and LC/MS of pungent piperamides in commercial black, white, green, and red whole and ground peppercorns. J Agric Food Chem 2008 56 3028-3036
-
(2008)
J Agric Food Chem
, vol.56
, pp. 3028-3036
-
-
Friedman, M.1
Levin, C.E.2
Lee, S.-U.3
Lee, J.-S.4
Ohnisi-Kameyama, M.5
Kozukue, N.6
-
263
-
-
33644820017
-
-
In: Dyer L. A. Palmer A. N. editors Piper. A model genus for studies of evolution, chemical ecology, and trophic interactions Boston Kluwer Academic Publishers
-
Dyer L A., Dodson C D., Richards J. Isolation, synthesis, and evolutionary ecology of Piper amides. In: Dyer L A. Palmer A N. editors Piper. A model genus for studies of evolution, chemical ecology, and trophic interactions. Boston Kluwer Academic Publishers 2004 117-139
-
(2004)
Isolation, Synthesis, and Evolutionary Ecology of Piper Amides
, pp. 117-139
-
-
Dyer, L.A.1
Dodson, C.D.2
Richards, J.3
-
264
-
-
13244272050
-
Insecticidal amides from fruits of Piper nigrum Linn
-
Siddiqui B S., Gulzar T, Begum S, Afshan F, Sattar F A. Insecticidal amides from fruits of Piper nigrum Linn. Nat Prod Res 2005 19 143-150
-
(2005)
Nat Prod Res
, vol.19
, pp. 143-150
-
-
Siddiqui, B.S.1
Gulzar, T.2
Begum, S.3
Afshan, F.4
Sattar, F.A.5
-
265
-
-
0037181281
-
Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species
-
Park I-K, Lee S-G, Shin S-C, Park J-D, Ahn Y-J. Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species. J Agric Food Chem 2002 50 1866-1870
-
(2002)
J Agric Food Chem
, vol.50
, pp. 1866-1870
-
-
Park, I.-K.1
Lee, S.-G.2
Shin, S.-C.3
Park, J.-D.4
Ahn, Y.-J.5
-
266
-
-
0021931513
-
Biochemical basis of enhanced drug bioavailability by piperine: Evidence that piperine is a potent inhibitor of drug metabolism
-
Atal C K., Dubey R K., Singh J. Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism. J Pharmacol Exp Ther 1985 232 258-262
-
(1985)
J Pharmacol Exp Ther
, vol.232
, pp. 258-262
-
-
Atal, C.K.1
Dubey, R.K.2
Singh, J.3
-
267
-
-
0022657175
-
Piperine-mediated inhibition of glucuronidation activity in isolated epithelial cells of the guinea-pig small intestine: Evidence that piperine lowers the endogenous UDP-glucuronic acid content
-
Singh J, Dubey R K., Atal C K. Piperine-mediated inhibition of glucuronidation activity in isolated epithelial cells of the guinea-pig small intestine: evidence that piperine lowers the endogenous UDP-glucuronic acid content. J Pharmacol Exp Ther 1986 236 488-493
-
(1986)
J Pharmacol Exp Ther
, vol.236
, pp. 488-493
-
-
Singh, J.1
Dubey, R.K.2
Atal, C.K.3
-
268
-
-
0025773244
-
Differences in the effects of piperine and piperonyl butoxide on hepatic drug-metabolizing enzyme system in rats
-
Dalvi R R., Dalvi P S. Differences in the effects of piperine and piperonyl butoxide on hepatic drug-metabolizing enzyme system in rats. Drug Chem Toxicol 1991 14 219-229
-
(1991)
Drug Chem Toxicol
, vol.14
, pp. 219-229
-
-
Dalvi, R.R.1
Dalvi, P.S.2
-
269
-
-
0025779774
-
In vitro and in vivo inhibition of pulmonary cytochrome P450 activities by piperine, a major ingredient of Piper species
-
Reen R K., Singh J. In vitro and in vivo inhibition of pulmonary cytochrome P450 activities by piperine, a major ingredient of Piper species. Indian J Exp Biol 1991 29 568-573
-
(1991)
Indian J Exp Biol
, vol.29
, pp. 568-573
-
-
Reen, R.K.1
Singh, J.2
-
270
-
-
0027249976
-
Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine
-
Reen R K., Jamwal D S., Taneja S C., Koul J L., Dubey R K., Wiebel F J., Singh J. Impairment of UDP-glucose dehydrogenase and glucuronidation activities in liver and small intestine of rat and guinea pig in vitro by piperine. Biochem Pharmacol 1993 46 229-238
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 229-238
-
-
Reen, R.K.1
Jamwal, D.S.2
Taneja, S.C.3
Koul, J.L.4
Dubey, R.K.5
Wiebel, F.J.6
Singh, J.7
-
271
-
-
0029671233
-
Piperine impairs cytochrome P4501A1 activity by direct interaction with the enzyme and not by down regulation of CYP1A1 gene expression in the rat hepatoma 5 L cell line
-
Reen R K., Roesch S F., Kiefer F, Wiebel F J., Singh J. Piperine impairs cytochrome P4501A1 activity by direct interaction with the enzyme and not by down regulation of CYP1A1 gene expression in the rat hepatoma 5 L cell line. Biochem Biophys Res Commun 1996 218 562-569
-
(1996)
Biochem Biophys Res Commun
, vol.218
, pp. 562-569
-
-
Reen, R.K.1
Roesch, S.F.2
Kiefer, F.3
Wiebel, F.J.4
Singh, J.5
-
272
-
-
0030819233
-
Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1
-
Reen R K., Wiebel F J., Singh J. Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1. J Ethnopharmacol 1997 58 165-173
-
(1997)
J Ethnopharmacol
, vol.58
, pp. 165-173
-
-
Reen, R.K.1
Wiebel, F.J.2
Singh, J.3
-
273
-
-
0033999464
-
Structure-activity relationship of piperine and its synthetic analogues for their inhibitory potentials of rat hepatic microsomal constitutive and inducible cytochrome P450 activities
-
Koul S, Koul J L., Taneja S C., Dhar K L., Jamwal D S., Singh K, Reen R K., Singh J. Structure-activity relationship of piperine and its synthetic analogues for their inhibitory potentials of rat hepatic microsomal constitutive and inducible cytochrome P450 activities. Bioorg Med Chem 2000 8 251-268
-
(2000)
Bioorg Med Chem
, vol.8
, pp. 251-268
-
-
Koul, S.1
Koul, J.L.2
Taneja, S.C.3
Dhar, K.L.4
Jamwal, D.S.5
Singh, K.6
Reen, R.K.7
Singh, J.8
-
274
-
-
0036070626
-
Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4
-
Bhardwaj R K., Glaeser H, Becquemont L, Klotz U, Gupta S K., Fromm M F. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002 302 645-650
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 645-650
-
-
Bhardwaj, R.K.1
Glaeser, H.2
Becquemont, L.3
Klotz, U.4
Gupta, S.K.5
Fromm, M.F.6
-
275
-
-
33744913556
-
Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum
-
Subehan, Usia T, Kadota S, Tezuka Y. Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum. Planta Med 2006 72 527-532
-
(2006)
Planta Med
, vol.72
, pp. 527-532
-
-
Subehan1
Usia, T.2
Kadota, S.3
Tezuka, Y.4
-
276
-
-
34248170837
-
Influence of curcumin, capsaicin, and piperine on the rat liver drug-metabolizing enzyme system in vivo and in vitro
-
Suresh D, Srinivasan K. Influence of curcumin, capsaicin, and piperine on the rat liver drug-metabolizing enzyme system in vivo and in vitro. Can J Physiol Pharmacol 2006 84 1259-1265
-
(2006)
Can J Physiol Pharmacol
, vol.84
, pp. 1259-1265
-
-
Suresh, D.1
Srinivasan, K.2
-
277
-
-
47949101818
-
Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor
-
Volak L P., Ghirmai S, Cashman J R., Court M H. Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor. Drug Metab Dispos 2008 36 1594-1605
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 1594-1605
-
-
Volak, L.P.1
Ghirmai, S.2
Cashman, J.R.3
Court, M.H.4
-
278
-
-
46749147175
-
In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression
-
Han Y, Tan T M. C., Lim L-Y. In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression. Toxicol Appl Pharmacol 2008 230 283-289
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, pp. 283-289
-
-
Han, Y.1
Tan, T.M.C.2
Lim, L.-Y.3
-
279
-
-
0036192768
-
Effect of co-administration of piperine on pharmacokinetics of beta-lactam antibiotics in rats
-
Hiwale A R., Dhuley J N., Naik S R. Effect of co-administration of piperine on pharmacokinetics of beta-lactam antibiotics in rats. Indian J Exp Biol 2002 40 277-281
-
(2002)
Indian J Exp Biol
, vol.40
, pp. 277-281
-
-
Hiwale, A.R.1
Dhuley, J.N.2
Naik, S.R.3
-
281
-
-
76049117213
-
Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells
-
Okura T, Ibe M, Umegaki K, Shinozuka K, Yamada S. Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells. Biol Pharm Bull 2010 33 255-259
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 255-259
-
-
Okura, T.1
Ibe, M.2
Umegaki, K.3
Shinozuka, K.4
Yamada, S.5
-
282
-
-
77349121410
-
Modulation of P-glycoprotein ATPase activity by some phytoconstituents
-
Najar I A., Sachin B S., Sharma S C., Satti N K., Suri K A., Johri R K. Modulation of P-glycoprotein ATPase activity by some phytoconstituents. Phytother Res 2010 24 454-458
-
(2010)
Phytother Res
, vol.24
, pp. 454-458
-
-
Najar, I.A.1
Sachin, B.S.2
Sharma, S.C.3
Satti, N.K.4
Suri, K.A.5
Johri, R.K.6
-
283
-
-
77953907984
-
Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction
-
Jin M J., Han H K. Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction. J Food Sci 2010 75 H93-H96
-
(2010)
J Food Sci
, vol.75
-
-
Jin, M.J.1
Han, H.K.2
-
284
-
-
17244367032
-
Chemopreventative effect of piperine on mitochrondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice
-
Selvendiran K, Thirunavukkarasu C, Singh J P. V., Padmavathi R, Sakthisekaran D. Chemopreventative effect of piperine on mitochrondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. Mol Cell Biochem 2005 271 101-106
-
(2005)
Mol Cell Biochem
, vol.271
, pp. 101-106
-
-
Selvendiran, K.1
Thirunavukkarasu, C.2
Singh, J.P.V.3
Padmavathi, R.4
Sakthisekaran, D.5
-
285
-
-
0025870866
-
Comparison of the effects of piperine administered intragastrically and intraperitoneally on the liver and liver mixed-function oxidases on rats
-
Dalvi R R., Dalvi P S. Comparison of the effects of piperine administered intragastrically and intraperitoneally on the liver and liver mixed-function oxidases on rats. Drug Metabol Drug Interact 1991 9 23-30
-
(1991)
Drug Metabol Drug Interact
, vol.9
, pp. 23-30
-
-
Dalvi, R.R.1
Dalvi, P.S.2
-
286
-
-
0028631445
-
Piperine effects on the expression of P4502E1, P4502B, and P4501A in rat
-
Kang M H., Won S M., Park S S., Kim S G., Novak R F., Kim N D. Piperine effects on the expression of P4502E1, P4502B, and P4501A in rat. Xenobiotica 1994 24 1195-1204
-
(1994)
Xenobiotica
, vol.24
, pp. 1195-1204
-
-
Kang, M.H.1
Won, S.M.2
Park, S.S.3
Kim, S.G.4
Novak, R.F.5
Kim, N.D.6
-
287
-
-
0036250151
-
Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics
-
Khajuria A, Thusu N, Zutshi U. Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics. Phytomedicine 2002 9 224-231
-
(2002)
Phytomedicine
, vol.9
, pp. 224-231
-
-
Khajuria, A.1
Thusu, N.2
Zutshi, U.3
-
288
-
-
0022023059
-
Influence of piperine on rifampicin blood levels in patients of pulmonary tuberculosis
-
Zutshi R K., Singh R, Zutshi U, Johri R K., Atal C K. Influence of piperine on rifampicin blood levels in patients of pulmonary tuberculosis. JAPI 1985 33 223-224
-
(1985)
JAPI
, vol.33
, pp. 223-224
-
-
Zutshi, R.K.1
Singh, R.2
Zutshi, U.3
Johri, R.K.4
Atal, C.K.5
-
289
-
-
0023492467
-
The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers
-
Bano G, Amla V, Raina R K., Zutshi U, Chopra C L. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Planta Med 1987 53 568-569
-
(1987)
Planta Med
, vol.53
, pp. 568-569
-
-
Bano, G.1
Amla, V.2
Raina, R.K.3
Zutshi, U.4
Chopra, C.L.5
-
290
-
-
0025930990
-
Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers
-
Bano G, Raina R K., Zutshi U, Bedi K L., Johri R K., Sharma S C. Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol 1991 41 615-617
-
(1991)
Eur J Clin Pharmacol
, vol.41
, pp. 615-617
-
-
Bano, G.1
Raina, R.K.2
Zutshi, U.3
Bedi, K.L.4
Johri, R.K.5
Sharma, S.C.6
-
291
-
-
0035686099
-
Piperine in food: Interference in the pharmacokinetics of phenytoin
-
Velpandian T, Jasuja R, Bhardwaj R K., Jaiseal J, Gupta S K. Piperine in food: interference in the pharmacokinetics of phenytoin. Eur J Drug Metab Pharmacokinet 2001 26 241-248
-
(2001)
Eur J Drug Metab Pharmacokinet
, vol.26
, pp. 241-248
-
-
Velpandian, T.1
Jasuja, R.2
Bhardwaj, R.K.3
Jaiseal, J.4
Gupta, S.K.5
-
292
-
-
33747309787
-
Effect of piperine on the steady-state pharmacokinetics of phenytoin in patients with epilepsy
-
Pattanaik S, Hota D, Prabhakar S, Kharbanda P, Pandhi P. Effect of piperine on the steady-state pharmacokinetics of phenytoin in patients with epilepsy. Phytother Res 2006 20 683-686
-
(2006)
Phytother Res
, vol.20
, pp. 683-686
-
-
Pattanaik, S.1
Hota, D.2
Prabhakar, S.3
Kharbanda, P.4
Pandhi, P.5
-
293
-
-
35548948992
-
Influence of piperine on the pharmacokinetics of nevirapine under fasting conditions: A randomized, crossover, placebo-controlled study
-
Kasibhatta R, Naidu M U. R. Influence of piperine on the pharmacokinetics of nevirapine under fasting conditions: a randomized, crossover, placebo-controlled study. Drugs R D 2007 8 383-391
-
(2007)
Drugs R D
, vol.8
, pp. 383-391
-
-
Kasibhatta, R.1
Naidu, M.U.R.2
-
295
-
-
69249093874
-
Systemic delivery of curcumin: 21st century solutions for an ancient conundrum
-
Bisht S, Maitra A. Systemic delivery of curcumin: 21st century solutions for an ancient conundrum. Curr Drug Discov Technol 2009 6 192-199
-
(2009)
Curr Drug Discov Technol
, vol.6
, pp. 192-199
-
-
Bisht, S.1
Maitra, A.2
-
296
-
-
0031860081
-
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
-
Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas P S. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 1998 64 353-356
-
(1998)
Planta Med
, vol.64
, pp. 353-356
-
-
Shoba, G.1
Joy, D.2
Joseph, T.3
Majeed, M.4
Rajendran, R.5
Srinivas, P.S.6
-
297
-
-
3543088026
-
Piperine enhances the bioavailability of the tea polyphenol ()-epigallocatechin-3-gallate in mice
-
Lambert J D., Hong J, Kim D H., Mishin V M., Yang C S. Piperine enhances the bioavailability of the tea polyphenol ()-epigallocatechin-3-gallate in mice. J Nutr 2004 134 1948-1952
-
(2004)
J Nutr
, vol.134
, pp. 1948-1952
-
-
Lambert, J.D.1
Hong, J.2
Kim, D.H.3
Mishin, V.M.4
Yang, C.S.5
-
298
-
-
45449105337
-
Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine
-
Panossian A, Wikman G. Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine. J Ethnopharmacol 2008 118 183-212
-
(2008)
J Ethnopharmacol
, vol.118
, pp. 183-212
-
-
Panossian, A.1
Wikman, G.2
-
301
-
-
33645976829
-
Dibenzocyclooctadiene lingnans: A class of novel inhibitors of P-glycoprotein
-
Pan Q, Lu Q, Zhang K, Hu X. Dibenzocyclooctadiene lingnans: a class of novel inhibitors of P-glycoprotein. Cancer Chemother Pharmacol 2006 58 99-106
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 99-106
-
-
Pan, Q.1
Lu, Q.2
Zhang, K.3
Hu, X.4
-
302
-
-
33748040419
-
Gomisin A alters substrate interaction and reverses P-glycoprotein- mediated multidrug resistance in HepG2-DR cells
-
Wan C-K, Zhu G-Y, Shen X-L, Chattopadhyay A, Dey S, Fong W-F. Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells. Biochem Pharmacol 2006 72 824-837
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 824-837
-
-
Wan, C.-K.1
Zhu, G.-Y.2
Shen, X.-L.3
Chattopadhyay, A.4
Dey, S.5
Fong, W.-F.6
-
303
-
-
34250365825
-
Effects of Schisandra lignans on P-glycoprotein-mediated efflux in human intestinal Caco-2 cells
-
Yoo H H., Lee M, Lee M W., Lim S Y., Shin J, Kim D-H. Effects of Schisandra lignans on P-glycoprotein-mediated efflux in human intestinal Caco-2 cells. Planta Med 2007 73 444-450
-
(2007)
Planta Med
, vol.73
, pp. 444-450
-
-
Yoo, H.H.1
Lee, M.2
Lee, M.W.3
Lim, S.Y.4
Shin, J.5
Kim, D.-H.6
-
304
-
-
39449137237
-
Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - An in vit ro model of intestinal transport
-
Madgula V L. M., Avula B, Choi Y W., Pullela S V., Khan I A., Walker L A., Khan S I. Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - an in vit ro model of intestinal transport. J Pharm Pharmacol 2008 60 363-370
-
(2008)
J Pharm Pharmacol
, vol.60
, pp. 363-370
-
-
Madgula, V.L.M.1
Avula, B.2
Choi, Y.W.3
Pullela, S.V.4
Khan, I.A.5
Walker, L.A.6
Khan, S.I.7
-
305
-
-
51849149141
-
Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae
-
Huang M, Jin J, Sun H, Liu G T. Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae. Cancer Chemother Pharmacol 2008 62 1015-1026
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 1015-1026
-
-
Huang, M.1
Jin, J.2
Sun, H.3
Liu, G.T.4
-
306
-
-
68049086622
-
Dibenzocyclooctadiene lignans overcome drug resistance in lung cancer cells - Study of structure-activity relationship
-
Slaninov I, Brezinov L, Koubikov L, Slanina J. Dibenzocyclooctadiene lignans overcome drug resistance in lung cancer cells - study of structure-activity relationship. Toxicol In Vitro 2009 23 1047-1054
-
(2009)
Toxicol in Vitro
, vol.23
, pp. 1047-1054
-
-
Slaninov, I.1
Brezinov, L.2
Koubikov, L.3
Slanina, J.4
-
307
-
-
85009545929
-
Inhibition of human liver microsomal CYP3A4 and CYP2D6 by extracts from 78 herbal medicines
-
Iwata H, Tezuka Y, Usia T, Kadota S, Hiratsuka A, Watabe T. Inhibition of human liver microsomal CYP3A4 and CYP2D6 by extracts from 78 herbal medicines. J Tradit Med 2004 21 42-50
-
(2004)
J Tradit Med
, vol.21
, pp. 42-50
-
-
Iwata, H.1
Tezuka, Y.2
Usia, T.3
Kadota, S.4
Hiratsuka, A.5
Watabe, T.6
-
308
-
-
9444257635
-
Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract
-
Iwata H, Tezuka Y, Kadota S, Hiratuska A, Watabe T. Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract. Drug Metab Dispos 2004 32 1351-1358
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1351-1358
-
-
Iwata, H.1
Tezuka, Y.2
Kadota, S.3
Hiratuska, A.4
Watabe, T.5
-
309
-
-
33749430489
-
Does a Kampo medicine containing Schisandra fruit affect pharmacokinetics of nifedipine like grapefruit juice
-
Makino T, Mizuno F, Mizukami H. Does a Kampo medicine containing Schisandra fruit affect pharmacokinetics of nifedipine like grapefruit juice? Biol Pharm Bull 2006 29 2065-2069
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 2065-2069
-
-
Makino, T.1
Mizuno, F.2
Mizukami, H.3
-
310
-
-
33644777715
-
Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats
-
Mu Y, Zhang J, Zhang S, Zhou H-H, Toma D, Ren S, Huang L, Yaramus M, Baum A, Venkataramanan R, Xie W. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. J Pharmacol Exp Ther 2006 316 1369-1377
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 1369-1377
-
-
Mu, Y.1
Zhang, J.2
Zhang, S.3
Zhou, H.-H.4
Toma, D.5
Ren, S.6
Huang, L.7
Yaramus, M.8
Baum, A.9
Venkataramanan, R.10
Xie, W.11
-
311
-
-
71049138996
-
Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats
-
Lai L, Hao H, Wang Q, Zheng C, Zhou F, Liu Y, Wang Y, Yu G, Kang A, Peng Y, Wang G, Chen X. Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats. Drug Metab Dispos 2009 37 2399-2407
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 2399-2407
-
-
Lai, L.1
Hao, H.2
Wang, Q.3
Zheng, C.4
Zhou, F.5
Liu, Y.6
Wang, Y.7
Yu, G.8
Kang, A.9
Peng, Y.10
Wang, G.11
Chen, X.12
-
312
-
-
77349105712
-
Mechanistic understanding of the different effects of Wuzhi tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of tacrolimus (FK506)
-
Qin X L., Bi H C., Wang X D., Li J L., Wang Y, Xue X P., Chen X, Wang C X., Xu L J., Wang Y T., Huang M. Mechanistic understanding of the different effects of Wuzhi tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of tacrolimus (FK506). Int J Pharm 2010 389 114-121
-
(2010)
Int J Pharm
, vol.389
, pp. 114-121
-
-
Qin, X.L.1
Bi, H.C.2
Wang, X.D.3
Li, J.L.4
Wang, Y.5
Xue, X.P.6
Chen, X.7
Wang, C.X.8
Xu, L.J.9
Wang, Y.T.10
Huang, M.11
-
313
-
-
70449379202
-
Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2
-
Lee S B., Kim C Y., Lee H J., Yun J H., Nho C W. Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2. Planta Med 2009 75 1314-1318
-
(2009)
Planta Med
, vol.75
, pp. 1314-1318
-
-
Lee, S.B.1
Kim, C.Y.2
Lee, H.J.3
Yun, J.H.4
Nho, C.W.5
-
314
-
-
77955294499
-
Enhancement of oral bioavailability of paclitaxel after oral administration of schisandrol B in rats
-
Jin J, Bi H, Hu J, Zhong G, Zhao L, Huang Z, Huang M. Enhancement of oral bioavailability of paclitaxel after oral administration of schisandrol B in rats. Biopharm Drug Dispos 2010 31 264-268
-
(2010)
Biopharm Drug Dispos
, vol.31
, pp. 264-268
-
-
Jin, J.1
Bi, H.2
Hu, J.3
Zhong, G.4
Zhao, L.5
Huang, Z.6
Huang, M.7
-
315
-
-
0020038221
-
Pharmacological properties of dibenzo[ a,c ]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. II. Induction of phenobarbital-like hepatic monooxygenases
-
Liu K-T, Cresteil T, Columelli S, Lesca P. Pharmacological properties of dibenzo[ a,c ]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. II. Induction of phenobarbital-like hepatic monooxygenases. Chem Biol Interact 1982 39 315-319
-
(1982)
Chem Biol Interact
, vol.39
, pp. 315-319
-
-
Liu, K.-T.1
Cresteil, T.2
Columelli, S.3
Lesca, P.4
-
316
-
-
0021979963
-
The effects of dietary Brussels sprouts and Schizandra chinensis on the xenobiotic-metabolizing enzymes of the rat small intestine
-
Salbe A D., Bjeldanes L F. The effects of dietary Brussels sprouts and Schizandra chinensis on the xenobiotic-metabolizing enzymes of the rat small intestine. Food Chem Toxicol 1985 23 57-65
-
(1985)
Food Chem Toxicol
, vol.23
, pp. 57-65
-
-
Salbe, A.D.1
Bjeldanes, L.F.2
-
317
-
-
34548615016
-
Effects of Schisandra sphenanthera extract on the pharmacokinetics of tacrolimus in healthy volunteers
-
Xin H-W, Wu X-C, Li Q, Yu A-R, Zhu M, Shen Y, Su D, Xiong L. Effects of Schisandra sphenanthera extract on the pharmacokinetics of tacrolimus in healthy volunteers. Br J Clin Pharmacol 2007 64 469-475
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 469-475
-
-
Xin, H.-W.1
Wu, X.-C.2
Li, Q.3
Yu, A.-R.4
Zhu, M.5
Shen, Y.6
Su, D.7
Xiong, L.8
-
318
-
-
77949451360
-
Effect of Schisandra sphenanthera extract on the concentration of tacrolimus in the blood of liver transplant patients
-
Jiang W, Wang X, Xu X, Kong L. Effect of Schisandra sphenanthera extract on the concentration of tacrolimus in the blood of liver transplant patients. Int J Clin Pharmacol Ther 2010 48 224-229
-
(2010)
Int J Clin Pharmacol Ther
, vol.48
, pp. 224-229
-
-
Jiang, W.1
Wang, X.2
Xu, X.3
Kong, L.4
-
319
-
-
65349149399
-
Effects of Schisandra sphenanthera extract on the pharmacokinetics of midazolam in healthy volunteers
-
Xin H-W, Wu X-C, Li Q, Yu A-R, Xiong L. Effects of Schisandra sphenanthera extract on the pharmacokinetics of midazolam in healthy volunteers. Br J Clin Pharmacol 2009 67 541-546
-
(2009)
Br J Clin Pharmacol
, vol.67
, pp. 541-546
-
-
Xin, H.-W.1
Wu, X.-C.2
Li, Q.3
Yu, A.-R.4
Xiong, L.5
-
320
-
-
0028956461
-
Silybum marianum (Carduus marianus)
-
Morazzoni P, Bombardelli E. Silybum marianum (Carduus marianus). Fitoterapia 1995 64 3-42
-
(1995)
Fitoterapia
, vol.64
, pp. 3-42
-
-
Morazzoni, P.1
Bombardelli, E.2
-
321
-
-
34249884261
-
Milk thistle nomenclature: Why it matters in cancer research and
-
Kroll D J., Shaw H S., Oberlies N H. Milk thistle nomenclature: why it matters in cancer research and pharmacokinetic studies. Integr Cancer Ther 2007 6 110-119
-
(2007)
Integr Cancer Ther
, vol.6
, pp. 110-119
-
-
Kroll, D.J.1
Shaw, H.S.2
Oberlies, N.H.3
-
322
-
-
0035211762
-
The use of silymarin in the treatment of liver diseases
-
Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs 2001 61 2035-2063
-
(2001)
Drugs
, vol.61
, pp. 2035-2063
-
-
Saller, R.1
Meier, R.2
Brignoli, R.3
-
323
-
-
33644652006
-
Milk thistle for alcoholic and/or hepatitis B or C liver diseases - A systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials
-
Rambaldi A, Jacobs B P., Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases - a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Am J Gastroenterol 2005 100 2583-2591
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2583-2591
-
-
Rambaldi, A.1
Jacobs, B.P.2
Iaquinto, G.3
Gluud, C.4
-
324
-
-
34249907027
-
Review of clinical trials evaluating safety and efficacy of milk thistle (Silybum marianum [L.] Gaertn.)
-
Tamayo C, Diamond S. Review of clinical trials evaluating safety and efficacy of milk thistle (Silybum marianum [L.] Gaertn.). Integr Cancer Ther 2007 6 146-157
-
(2007)
Integr Cancer Ther
, vol.6
, pp. 146-157
-
-
Tamayo, C.1
Diamond, S.2
-
325
-
-
40549139768
-
An updated systematic review with meta-analysis for the clinical evidence of silymarin
-
Saller R, Brignoli R, Melzer J, Meier R. An updated systematic review with meta-analysis for the clinical evidence of silymarin. Forsch Komplementmed 2008 15 9-20
-
(2008)
Forsch Komplementmed
, vol.15
, pp. 9-20
-
-
Saller, R.1
Brignoli, R.2
Melzer, J.3
Meier, R.4
-
326
-
-
64649096872
-
A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis
-
El-Kamary S S., Shardell M D., Abdel-Hamid M, Ismail S, El-Ateek M, Metwally M, Mikhail N, Hashem M, Mousa A, Aboul-Fotouh A, El-Kassas M, Esmat G, Strickland G T. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. Phytomedicine 2009 16 391-400
-
(2009)
Phytomedicine
, vol.16
, pp. 391-400
-
-
El-Kamary, S.S.1
Shardell, M.D.2
Abdel-Hamid, M.3
Ismail, S.4
El-Ateek, M.5
Metwally, M.6
Mikhail, N.7
Hashem, M.8
Mousa, A.9
Aboul-Fotouh, A.10
El-Kassas, M.11
Esmat, G.12
Strickland, G.T.13
-
328
-
-
0347503514
-
Comparative bioavailability of silibinin in healthy male volunteers
-
Kim Y C., Kim E J., Lee E D., Kim J H., Jang S W., Kim Y G., Kwon J W., Kim W B., Lee M G. Comparative bioavailability of silibinin in healthy male volunteers. Int J Clin Pharmacol Ther 2003 41 593-596
-
(2003)
Int J Clin Pharmacol Ther
, vol.41
, pp. 593-596
-
-
Kim, Y.C.1
Kim, E.J.2
Lee, E.D.3
Kim, J.H.4
Jang, S.W.5
Kim, Y.G.6
Kwon, J.W.7
Kim, W.B.8
Lee, M.G.9
-
329
-
-
50049099550
-
The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic fatty liver disease and correlates with plasma caspase-3/7 activity
-
Schrieber S J., Wen Z, Vourvahis M, Smith P C., Fried M W., Kashuba A D. M., Hawke R L. The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic fatty liver disease and correlates with plasma caspase-3/7 activity. Drug Metab Dispos 2008 36 1909-1916
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 1909-1916
-
-
Schrieber, S.J.1
Wen, Z.2
Vourvahis, M.3
Smith, P.C.4
Fried, M.W.5
Kashuba, A.D.M.6
Hawke, R.L.7
-
330
-
-
37549005182
-
Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract
-
Wen Z, Dumas T E., Schrieber S J., Hawke R L., Fried M W., Smith P C. Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. Drug Metab Dispos 2008 36 65-72
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 65-72
-
-
Wen, Z.1
Dumas, T.E.2
Schrieber, S.J.3
Hawke, R.L.4
Fried, M.W.5
Smith, P.C.6
-
331
-
-
77957265017
-
Silymarin ascending multiple oral dosing phase i study in noncirrhotic patients with chronic hepatitis C
-
Hawke R L., Schrieber S J., Soule T A., Wen Z, Smith P C., Reddy R, Wahed A S., Belle S H., Afdhal N H., Navarro V J., Berman J, Liu Q-Y, Doo E, Fried M W. Silymarin ascending multiple oral dosing phase I study in noncirrhotic patients with chronic hepatitis C. J Clin Pharmacol 2010 50 434-449
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 434-449
-
-
Hawke, R.L.1
Schrieber, S.J.2
Soule, T.A.3
Wen, Z.4
Smith, P.C.5
Reddy, R.6
Wahed, A.S.7
Belle, S.H.8
Afdhal, N.H.9
Navarro, V.J.10
Berman, J.11
Liu, Q.-Y.12
Doo, E.13
Fried, M.W.14
-
332
-
-
0028301966
-
Hepatoprotective mechanism of silymarin: No evidence for involvement of cytochrome P450 2E1
-
Miguez M-P, Anundi I, Sainz-Pardo L A., Lindros K O. Hepatoprotective mechanism of silymarin: no evidence for involvement of cytochrome P450 2E1. Chem Biol Interact 1994 91 51-63
-
(1994)
Chem Biol Interact
, vol.91
, pp. 51-63
-
-
Miguez, M.-P.1
Anundi, I.2
Sainz-Pardo, L.A.3
Lindros, K.O.4
-
333
-
-
0033782925
-
Milk thistle, a herbal supplement, decreases the activity of CYP3A4 and uridine diphosphoglucuronosyl transferase in human hepatocyte cultures
-
Venkataramanan R, Ramachandran V, Komoroski B J., Zhang S, Schiff P L., Strom S C. Milk thistle, a herbal supplement, decreases the activity of CYP3A4 and uridine diphosphoglucuronosyl transferase in human hepatocyte cultures. Drug Metab Dispos 2000 28 1270-1273
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1270-1273
-
-
Venkataramanan, R.1
Ramachandran, V.2
Komoroski, B.J.3
Zhang, S.4
Schiff, P.L.5
Strom, S.C.6
-
334
-
-
0034045694
-
Inhibitory effects of silibin on cytochrome P-450 enzymes in human liver microsomes
-
Beckmann-Knopp S, Rietbrock S, Weyhenmeyer R, Böcker R H., Beckurts T, Lang W, Hunz M, Fuhr U. Inhibitory effects of silibin on cytochrome P-450 enzymes in human liver microsomes. Pharmacol Toxicol 2000 86 250-256
-
(2000)
Pharmacol Toxicol
, vol.86
, pp. 250-256
-
-
Beckmann-Knopp, S.1
Rietbrock, S.2
Weyhenmeyer, R.3
Böcker, R.H.4
Beckurts, T.5
Lang, W.6
Hunz, M.7
Fuhr, U.8
-
335
-
-
0036846701
-
Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities
-
Zuber R, Modriansk M, Dvork Z, Rohovsk P, Ulrichov J, Simnek V, Anzenbacher P. Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities. Phytother Res 2002 16 632-638
-
(2002)
Phytother Res
, vol.16
, pp. 632-638
-
-
Zuber, R.1
Modriansk, M.2
Dvork, Z.3
Rohovsk, P.4
Ulrichov, J.5
Simnek, V.6
Anzenbacher, P.7
-
336
-
-
2442649042
-
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyl-transferases
-
Sridar C, Goosen T C., Kent U M., Williams J A., Hollenberg P F. Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyl-transferases. Drug Metab Dispos 2004 32 587-594
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 587-594
-
-
Sridar, C.1
Goosen, T.C.2
Kent, U.M.3
Williams, J.A.4
Hollenberg, P.F.5
-
337
-
-
5444251235
-
In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: Changes in P-gp and CYP3A4 activity
-
Patel J, Buddha B, Dey S, Pal D, Mitra A K. In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity. Am J Ther 2004 11 262-277
-
(2004)
Am J Ther
, vol.11
, pp. 262-277
-
-
Patel, J.1
Buddha, B.2
Dey, S.3
Pal, D.4
Mitra, A.K.5
-
338
-
-
35549001795
-
Silybin is metabolized by cytochrome P450 2C8 in vitro
-
Jancova P, Anzenbacherova E, Papouskova B, Lemr K, Luzna P, Veinlichova A, Anzenbacher P, Simanek V. Silybin is metabolized by cytochrome P450 2C8 in vitro. Drug Metab Dispos 2007 35 2035-2039
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 2035-2039
-
-
Jancova, P.1
Anzenbacherova, E.2
Papouskova, B.3
Lemr, K.4
Luzna, P.5
Veinlichova, A.6
Anzenbacher, P.7
Simanek, V.8
-
339
-
-
40049104526
-
Assessment of drug-drug interaction for silymarin
-
Doehmer J, Tewes B, Klein K-U, Gritzko K, Muschick H, Mengs U. Assessment of drug-drug interaction for silymarin. Toxicol In Vitro 2008 22 610-617
-
(2008)
Toxicol in Vitro
, vol.22
, pp. 610-617
-
-
Doehmer, J.1
Tewes, B.2
Klein, K.-U.3
Gritzko, K.4
Muschick, H.5
Mengs, U.6
-
340
-
-
77249169919
-
Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations
-
Brantley S J., Oberlies N H., Kroll D J., Paine M F. Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations. J Pharmacol Exp Ther 2010 332 1081-1087
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 1081-1087
-
-
Brantley, S.J.1
Oberlies, N.H.2
Kroll, D.J.3
Paine, M.F.4
-
341
-
-
0034677063
-
The flavanolignan silybin and its hemisynthetic derivatives, a novel series of potential modulators of P-glycoprotein
-
Maitrejean M, Comte G, Barron D, El Kirat K, Conseil G, Di Pietro A. The flavanolignan silybin and its hemisynthetic derivatives, a novel series of potential modulators of P-glycoprotein. Bioorg Med Chem Lett 2000 10 157-160
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 157-160
-
-
Maitrejean, M.1
Comte, G.2
Barron, D.3
El Kirat, K.4
Conseil, G.5
Di Pietro, A.6
-
342
-
-
0037371275
-
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
-
Zhang S, Morris M E. Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J Pharmacol Exp Ther 2003 304 1258-1267
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1258-1267
-
-
Zhang, S.1
Morris, M.E.2
-
343
-
-
0043127383
-
Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells
-
Zhang S, Morris M E. Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells. Pharm Res 2003 20 1184-1191
-
(2003)
Pharm Res
, vol.20
, pp. 1184-1191
-
-
Zhang, S.1
Morris, M.E.2
-
344
-
-
30544440659
-
Inhibition of P-glycoprotein by natural products in human breast cancer cells
-
Chung S Y., Sung M K., Kim N H., Jang J O., Go E J., Lee H J. Inhibition of P-glycoprotein by natural products in human breast cancer cells. Arch Pharm Res 2005 28 823-828
-
(2005)
Arch Pharm Res
, vol.28
, pp. 823-828
-
-
Chung, S.Y.1
Sung, M.K.2
Kim, N.H.3
Jang, J.O.4
Go, E.J.5
Lee, H.J.6
-
345
-
-
33644914487
-
Flavonoid-drug interactions: Effects of flavonoids on ABC transporters
-
Morris M E., Zhang S. Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci 2006 78 2116-2130
-
(2006)
Life Sci
, vol.78
, pp. 2116-2130
-
-
Morris, M.E.1
Zhang, S.2
-
346
-
-
54349084283
-
Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: Role of multidrug resistance-associated protein 2 (Abcc2)
-
Miranda S R., Lee J K., Brouwer K L. R., Wen Z, Smith P C., Hawke R L. Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2). Drug Metab Dispos 2008 36 2219-2226
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 2219-2226
-
-
Miranda, S.R.1
Lee, J.K.2
Brouwer, K.L.R.3
Wen, Z.4
Smith, P.C.5
Hawke, R.L.6
-
347
-
-
46749154716
-
Effect of silymarin supplement on the pharmacokinetics of rosuvastatin
-
Deng J W., Shon J-H, Shin H-J, Park S-J, Yeo C-W, Zhou H-H, Song P-S, Shin J-G. Effect of silymarin supplement on the pharmacokinetics of rosuvastatin. Pharm Res 2008 25 1807-1814
-
(2008)
Pharm Res
, vol.25
, pp. 1807-1814
-
-
Deng, J.W.1
Shon, J.-H.2
Shin, H.-J.3
Park, S.-J.4
Yeo, C.-W.5
Zhou, H.-H.6
Song, P.-S.7
Shin, J.-G.8
-
348
-
-
77954075760
-
Patented bioavailability enhancement techniques of silymarin
-
Javed S, Kohli K, Ali M. Patented bioavailability enhancement techniques of silymarin. Recent Pat Drug Deliv Formul 2010 4 145-152
-
(2010)
Recent Pat Drug Deliv Formul
, vol.4
, pp. 145-152
-
-
Javed, S.1
Kohli, K.2
Ali, M.3
-
349
-
-
0025645646
-
Pharmacokinetic studies on Idb 1016, a silybin-phosphatidylcholine complex, in normal human subjects
-
Barzaghi N, Crema F, Gatti G, Pifferi G, Perucca E. Pharmacokinetic studies on Idb 1016, a silybin-phosphatidylcholine complex, in normal human subjects. Eur J Drug Metab Pharmacokinet 1990 15 333-338
-
(1990)
Eur J Drug Metab Pharmacokinet
, vol.15
, pp. 333-338
-
-
Barzaghi, N.1
Crema, F.2
Gatti, G.3
Pifferi, G.4
Perucca, E.5
-
350
-
-
0028032478
-
Plasma concentrations of free and conjugated silybin after oral intake of a silybin-phosphatidylcholine complex (silipide) in healthy volunteers
-
Gatti G, Perucca E. Plasma concentrations of free and conjugated silybin after oral intake of a silybin-phosphatidylcholine complex (silipide) in healthy volunteers. Int J Clin Pharmacol Ther 1994 32 614-617
-
(1994)
Int J Clin Pharmacol Ther
, vol.32
, pp. 614-617
-
-
Gatti, G.1
Perucca, E.2
-
351
-
-
25644448238
-
A review of the bioavailability and clinical efficacy of milk thistle phytosome: A silybin-phosphatidylcholine complex (Siliphos)
-
Kidd P, Head K. A review of the bioavailability and clinical efficacy of milk thistle phytosome: a silybin-phosphatidylcholine complex (Siliphos). Altern Med Rev 2005 10 193-203
-
(2005)
Altern Med Rev
, vol.10
, pp. 193-203
-
-
Kidd, P.1
Head, K.2
-
352
-
-
70350068120
-
Bioavailability and activity of phytosome complexes from botanical polyphenols: The silymarin, curcumin, green tea, and grape seed extracts
-
Kidd P M. Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. Altern Med Rev 2009 14 226-246
-
(2009)
Altern Med Rev
, vol.14
, pp. 226-246
-
-
Kidd, P.M.1
-
353
-
-
33845899681
-
A phase i and pharmacokinetic study of silybin-phytosome in prostate cancer patients
-
Flaig T W., Gustafson D L., Su L-J, Zirrolli J A., Crighton F, Harrison G S., Pierson A S., Agarwal R, Glod L M. A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients. Invest New Drugs 2007 25 139-146
-
(2007)
Invest New Drugs
, vol.25
, pp. 139-146
-
-
Flaig, T.W.1
Gustafson, D.L.2
Su, L.-J.3
Zirrolli, J.A.4
Crighton, F.5
Harrison, G.S.6
Pierson, A.S.7
Agarwal, R.8
Glod, L.M.9
-
354
-
-
77952317006
-
A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer
-
Flaig T W., Glod M, Gustafson D, van Bokhoven A, Tao Y, Wilson S, Su L-J, Li Y, Harrison G, Agarwal R, Crawford E D., Lucia M S., Pollak M. A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer. Prostate 2010 70 848-855
-
(2010)
Prostate
, vol.70
, pp. 848-855
-
-
Flaig, T.W.1
Glod, M.2
Gustafson, D.3
Van Bokhoven, A.4
Tao, Y.5
Wilson, S.6
Su, L.-J.7
Li, Y.8
Harrison, G.9
Agarwal, R.10
Crawford, E.D.11
Lucia, M.S.12
Pollak, M.13
-
355
-
-
0017140376
-
Influence of silymarin on drug metabolizing enzymes in rat and man
-
Leber H W., Knauff S. Influence of silymarin on drug metabolizing enzymes in rat and man. Arzneimittelforschung 1976 26 1603-1605
-
(1976)
Arzneimittelforschung
, vol.26
, pp. 1603-1605
-
-
Leber, H.W.1
Knauff, S.2
-
356
-
-
0036239016
-
Effect of milk thistle on the pharmacokinetics of indinavir in healthy volunteers
-
Piscitelli S C., Formentini E, Burstein A H., Alfaro R, Jagannatha S, Falloon J. Effect of milk thistle on the pharmacokinetics of indinavir in healthy volunteers. Pharmacotherapy 2002 22 551-556
-
(2002)
Pharmacotherapy
, vol.22
, pp. 551-556
-
-
Piscitelli, S.C.1
Formentini, E.2
Burstein, A.H.3
Alfaro, R.4
Jagannatha, S.5
Falloon, J.6
-
357
-
-
20244375242
-
Milk thistle and indinavir: A randomized controlled pharmacokinetics study and meta analysis
-
Mills E, Wilson K, Clarke M, Foster B, Walker S, Rachlis B, DeGroot N, Montori V M., Gold W, Phillips E, Myers S, Gallicano K. Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta analysis. Eur J Clin Pharmacol 2005 61 1-7
-
(2005)
Eur J Clin Pharmacol
, vol.61
, pp. 1-7
-
-
Mills, E.1
Wilson, K.2
Clarke, M.3
Foster, B.4
Walker, S.5
Rachlis, B.6
Degroot, N.7
Montori, V.M.8
Gold, W.9
Phillips, E.10
Myers, S.11
Gallicano, K.12
-
358
-
-
0038720021
-
Coadministration of milk thistle and indinavir in healthy subjects
-
DiCenzo R, Shelton M, Jordan K, Koval C, Forrest A, Reichman R, Morse G. Coadministration of milk thistle and indinavir in healthy subjects. Pharmacotherapy 2003 23 866-870
-
(2003)
Pharmacotherapy
, vol.23
, pp. 866-870
-
-
Dicenzo, R.1
Shelton, M.2
Jordan, K.3
Koval, C.4
Forrest, A.5
Reichman, R.6
Morse, G.7
-
359
-
-
27744523714
-
Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan
-
van Erp N P. H., Baker S D., Zhao M, Rudek M A., Guchelaar H-J, Nortier J W. R., Sparreboom A, Gelderblom H. Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan. Clin Cancer Res 2005 11 7800-7806
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7800-7806
-
-
Van Erp, N.P.H.1
Baker, S.D.2
Zhao, M.3
Rudek, M.A.4
Guchelaar, H.-J.5
Nortier, J.W.R.6
Sparreboom, A.7
Gelderblom, H.8
-
360
-
-
36949011011
-
The effect of silymarin on oral nifedipine pharmacokinetics
-
Fuhr U, Beckmann-Knopp S, Jetter A, Lck H, Mengs U. The effect of silymarin on oral nifedipine pharmacokinetics. Planta Med 2007 73 1429-1435
-
(2007)
Planta Med
, vol.73
, pp. 1429-1435
-
-
Fuhr, U.1
Beckmann-Knopp, S.2
Jetter, A.3
Lck, H.4
Mengs, U.5
-
361
-
-
34547664909
-
Effect of silymarin on the oral bioavailability of ranitidine in healthy human volunteers
-
Rao B N., Srinivas M, Kumar Y S., Rao Y M. Effect of silymarin on the oral bioavailability of ranitidine in healthy human volunteers. Drug Metabol Drug Interact 2007 22 175-185
-
(2007)
Drug Metabol Drug Interact
, vol.22
, pp. 175-185
-
-
Rao, B.N.1
Srinivas, M.2
Kumar, Y.S.3
Rao, Y.M.4
-
362
-
-
70350509161
-
Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers
-
Han Y, Guo D, Chen Y, Tan Z-R, Zhou H-H. Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers. Xenobiotica 2009 39 694-699
-
(2009)
Xenobiotica
, vol.39
, pp. 694-699
-
-
Han, Y.1
Guo, D.2
Chen, Y.3
Tan, Z.-R.4
Zhou, H.-H.5
-
363
-
-
1342347958
-
Study on the influence of silymarin pretreatment on metabolism and disposition of metronidazole
-
Rajnarayana K, Reddy M S., Vidyasagar J, Krishna D R. Study on the influence of silymarin pretreatment on metabolism and disposition of metronidazole. Arzneimittelforschung 2004 54 109-113
-
(2004)
Arzneimittelforschung
, vol.54
, pp. 109-113
-
-
Rajnarayana, K.1
Reddy, M.S.2
Vidyasagar, J.3
Krishna, D.R.4
-
364
-
-
68849120724
-
Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteers
-
Han Y, Guo D, Chen Y, Chen Y, Tan Z-R, Zhou H-H. Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteers. Eur J Clin Pharmacol 2009 65 585-591
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 585-591
-
-
Han, Y.1
Guo, D.2
Chen, Y.3
Chen, Y.4
Tan, Z.-R.5
Zhou, H.-H.6
-
365
-
-
75649125625
-
A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL)
-
Ladas E J., Kroll D J., Oberlies N H., Cheng B, Ndao D H., Rheingold S R., Kelly K M. A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL). Cancer 2010 116 506-513
-
(2010)
Cancer
, vol.116
, pp. 506-513
-
-
Ladas, E.J.1
Kroll, D.J.2
Oberlies, N.H.3
Cheng, B.4
Ndao, D.H.5
Rheingold, S.R.6
Kelly, K.M.7
-
366
-
-
0037051930
-
Effect of Hypericum perforatum (St John's wort) in major depressive disorder: A randomized controlled trial
-
Hypericum Depression Trial Study Group
-
Hypericum Depression Trial Study Group. Effect of Hypericum perforatum (St John's wort) in major depressive disorder: a randomized controlled trial. JAMA 2002 14 1807-1814
-
(2002)
JAMA
, vol.14
, pp. 1807-1814
-
-
-
368
-
-
33748788822
-
Hyperforin
-
Beerhues L. Hyperforin. Phytochemistry 2006 67 2201-2207
-
(2006)
Phytochemistry
, vol.67
, pp. 2201-2207
-
-
Beerhues, L.1
-
369
-
-
77952983897
-
Lessons learned from herbal medicinal products: The example of St John's wort
-
Nahrstedt A, Butterweck V. Lessons learned from herbal medicinal products: the example of St John's wort. J Nat Prod 2010 73 1015-1021
-
(2010)
J Nat Prod
, vol.73
, pp. 1015-1021
-
-
Nahrstedt, A.1
Butterweck, V.2
-
370
-
-
33644822200
-
Hyperforin in St. John's wort interactions
-
Madabushi R, Frank B, Drewelow B, Derendorf H, Butterweck V. Hyperforin in St. John's wort interactions. Eur J Clin Pharmacol 2006 62 225-233
-
(2006)
Eur J Clin Pharmacol
, vol.62
, pp. 225-233
-
-
Madabushi, R.1
Frank, B.2
Drewelow, B.3
Derendorf, H.4
Butterweck, V.5
-
371
-
-
33749994006
-
The effect of St. John's wort extract on CYP3A: A systematic review of prospective clinical trials
-
Whitten D L., Myers S P., Hawrelak J A., Wohlmuth H. The effect of St. John's wort extract on CYP3A: a systematic review of prospective clinical trials. Br J Clin Pharmacol 2006 62 512-526
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 512-526
-
-
Whitten, D.L.1
Myers, S.P.2
Hawrelak, J.A.3
Wohlmuth, H.4
-
372
-
-
47349094025
-
An update on clinical drug interactions with the herbal antidepressant St John's wort
-
Zhou S-F, Lai X. An update on clinical drug interactions with the herbal antidepressant St John's wort. Curr Drug Metab 2008 9 394-409
-
(2008)
Curr Drug Metab
, vol.9
, pp. 394-409
-
-
Zhou, S.-F.1
Lai, X.2
-
373
-
-
62749096878
-
Molecular mechanisms underlying St. John's wort drug interactions
-
Kober M, Pohl K, Efferth T. Molecular mechanisms underlying St. John's wort drug interactions. Curr Drug Metab 2008 9 1027-1037
-
(2008)
Curr Drug Metab
, vol.9
, pp. 1027-1037
-
-
Kober, M.1
Pohl, K.2
Efferth, T.3
-
374
-
-
72949089249
-
Herb-drug interactions with St John's wort (Hypericum perforatum): An update on clinical observations
-
Borrelli F, Izzo A A. Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations. AAPS J 2009 11 710-727
-
(2009)
AAPS J
, vol.11
, pp. 710-727
-
-
Borrelli, F.1
Izzo, A.A.2
-
375
-
-
0034691064
-
St John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
-
Moore L B., Goodwin B, Jones S A., Wisely W B., Serabjit-Singh C J., Willson T M., Collins J L., Kliewer S A. St John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. Proc Natl Acad Sci USA 2000 97 7500-7502
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7500-7502
-
-
Moore, L.B.1
Goodwin, B.2
Jones, S.A.3
Wisely, W.B.4
Serabjit-Singh, C.J.5
Willson, T.M.6
Collins, J.L.7
Kliewer, S.A.8
-
376
-
-
0033826492
-
St John's wort, a herbal antidepressant, activates the steroid X receptor
-
Wentworth J M., Agostini M, Love J, Schwabe J W., Chatterjee V K. K. St John's wort, a herbal antidepressant, activates the steroid X receptor. J Endocrinol 2000 166 R11-R16
-
(2000)
J Endocrinol
, vol.166
-
-
Wentworth, J.M.1
Agostini, M.2
Love, J.3
Schwabe, J.W.4
Chatterjee, V.K.K.5
-
377
-
-
0037501542
-
2.1 crystal structure of human PXR in complex with the St John's wort compound hyperforin
-
Watkins R E., Maglich J M., Moore L B., Wisely G B., Noble S M., Davis-Searlies P R., Lambert M H., Kliewer S A., Redinbo M R. 2.1 crystal structure of human PXR in complex with the St John's wort compound hyperforin. Biochemistry 2003 42 1430-1438
-
(2003)
Biochemistry
, vol.42
, pp. 1430-1438
-
-
Watkins, R.E.1
Maglich, J.M.2
Moore, L.B.3
Wisely, G.B.4
Noble, S.M.5
Davis-Searlies, P.R.6
Lambert, M.H.7
Kliewer, S.A.8
Redinbo, M.R.9
-
378
-
-
27944492322
-
Antidepressant-like components of Hypericum perforatum extracts: An overview of their pharmacokinetics and metabolism
-
Caccia S. Antidepressant-like components of Hypericum perforatum extracts: an overview of their pharmacokinetics and metabolism. Curr Drug Metab 2005 6 531-543
-
(2005)
Curr Drug Metab
, vol.6
, pp. 531-543
-
-
Caccia, S.1
-
379
-
-
33646124719
-
Hypericum perforatum: A modern herbal antidepressant, pharmacokinetics of active ingredients
-
Wurglics M, Schubert-Zsilavecz M. Hypericum perforatum: a modern herbal antidepressant, pharmacokinetics of active ingredients. Clin Pharmacokinet 2006 45 449-468
-
(2006)
Clin Pharmacokinet
, vol.45
, pp. 449-468
-
-
Wurglics, M.1
Schubert-Zsilavecz, M.2
-
380
-
-
0035404326
-
Comparison of german St. John's wort products according to hyperforin and total hypericin content
-
Wurglics M, Westerhoff K, Kaunzinger A, Wilke A, Baumeister A, Dressman J, Schubert-Zsilavecz M. Comparison of german St. John's wort products according to hyperforin and total hypericin content. J Am Pharm Assoc 2001 41 560-566
-
(2001)
J Am Pharm Assoc
, vol.41
, pp. 560-566
-
-
Wurglics, M.1
Westerhoff, K.2
Kaunzinger, A.3
Wilke, A.4
Baumeister, A.5
Dressman, J.6
Schubert-Zsilavecz, M.7
-
381
-
-
34447625520
-
Variability in PXR-mediated induction of CYP3A4 by commercial preparations and dry extracts of St. John's wort
-
Gödtel-Armbrust U, Metzger A, Kroll U, Kelber O, Wojnowski L. Variability in PXR-mediated induction of CYP3A4 by commercial preparations and dry extracts of St. John's wort. Nauyn Schmiedebergs Arch Pharmacol 2007 375 377-382
-
(2007)
Nauyn Schmiedebergs Arch Pharmacol
, vol.375
, pp. 377-382
-
-
Gödtel-Armbrust, U.1
Metzger, A.2
Kroll, U.3
Kelber, O.4
Wojnowski, L.5
-
382
-
-
4744359869
-
Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction
-
Mai I, Bauer S, Perloff E S., Johne A, Uehleke B, Frank B, Budde K, Roots I. Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction. Clin Pharmacol Ther 2004 76 330-340
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 330-340
-
-
Mai, I.1
Bauer, S.2
Perloff, E.S.3
Johne, A.4
Uehleke, B.5
Frank, B.6
Budde, K.7
Roots, I.8
-
383
-
-
18744369624
-
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St. John's wort extract
-
Arold G, Donath F, Maurer A, Diefenbach K, Bauer S, Henneicke-von Zepelin H, Friede M, Roots I. No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St. John's wort extract. Planta Med 2005 71 331-337
-
(2005)
Planta Med
, vol.71
, pp. 331-337
-
-
Arold, G.1
Donath, F.2
Maurer, A.3
Diefenbach, K.4
Bauer, S.5
Henneicke-Von Zepelin, H.6
Friede, M.7
Roots, I.8
-
384
-
-
30844472028
-
The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose
-
Mueller S C., Majcher-Peszynska J, Uehleke B, Klammt S, Mundkowski R G., Miekisch W, Sievers H, Bauer S, Frank B, Kundt G, Drewelow B. The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose. Eur J Clin Pharmacol 2006 62 29-36
-
(2006)
Eur J Clin Pharmacol
, vol.62
, pp. 29-36
-
-
Mueller, S.C.1
Majcher-Peszynska, J.2
Uehleke, B.3
Klammt, S.4
Mundkowski, R.G.5
Miekisch, W.6
Sievers, H.7
Bauer, S.8
Frank, B.9
Kundt, G.10
Drewelow, B.11
-
385
-
-
61349163526
-
Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzyme
-
Wang X D., Li J L., Su Q B., Guan S, Chen J, Du J, He Y W., Zeng J, Zhang J X., Chen X. Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzyme. Br J Clin Pharmacol 2009 67 255-261
-
(2009)
Br J Clin Pharmacol
, vol.67
, pp. 255-261
-
-
Wang, X.D.1
Li, J.L.2
Su, Q.B.3
Guan, S.4
Chen, J.5
Du, J.6
He, Y.W.7
Zeng, J.8
Zhang, J.X.9
Chen, X.10
-
386
-
-
42149117406
-
The recovery time-course of CYP3A after induction by St John's wort administration
-
Imai H, Kotegawa T, Tsutsumi K, Morimoto T, Eshima N, Nakano S, Ohashi K. The recovery time-course of CYP3A after induction by St John's wort administration. Br J Clin Pharmacol 2008 65 701-707
-
(2008)
Br J Clin Pharmacol
, vol.65
, pp. 701-707
-
-
Imai, H.1
Kotegawa, T.2
Tsutsumi, K.3
Morimoto, T.4
Eshima, N.5
Nakano, S.6
Ohashi, K.7
-
387
-
-
77956756713
-
Applications of novel drug delivery system for herbal formulations
-
Ajazuddin S S. Applications of novel drug delivery system for herbal formulations. Fitoterapia 2010 81 680-689
-
(2010)
Fitoterapia
, vol.81
, pp. 680-689
-
-
Ajazuddin, S.S.1
-
388
-
-
79956312428
-
Emerging technologies for improving phytochemical bioavailability: Benefits and risks
-
Gurley B J. Emerging technologies for improving phytochemical bioavailability: benefits and risks. Clin Pharmacol Ther 2011 89 915-919
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 915-919
-
-
Gurley, B.J.1
-
389
-
-
33748671122
-
Effects of Hypericum perforatum on ivabradine pharmacokinetics in healthy volunteers: An open-label, pharmacokinetic interaction clinical trial
-
Portoles A, Terleira A, Calvo A, Martinez I, Resplandy G. Effects of Hypericum perforatum on ivabradine pharmacokinetics in healthy volunteers: an open-label, pharmacokinetic interaction clinical trial. J Clin Pharmacol 2006 46 1188-1194
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 1188-1194
-
-
Portoles, A.1
Terleira, A.2
Calvo, A.3
Martinez, I.4
Resplandy, G.5
-
390
-
-
0034520267
-
St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4
-
Drr D, Stieger B, Kullak-Ublick G A., Rentsch K M., Steinert H C., Meier P J., Fattinger K. St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4. Clin Pharmacol Ther 2000 68 598-604
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 598-604
-
-
Drr, D.1
Stieger, B.2
Kullak-Ublick, G.A.3
Rentsch, K.M.4
Steinert, H.C.5
Meier, P.J.6
Fattinger, K.7
-
391
-
-
0036157182
-
Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's wort (Hypericum perforatum)
-
Johne A, Schmider J, Brockmoller J, Stadelmann A M., Stormer E, Bauer S, Scholler G, Langheinrich M, Roots I. Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. John's wort (Hypericum perforatum). J Clin Psychopharmacol 2002 22 46-54
-
(2002)
J Clin Psychopharmacol
, vol.22
, pp. 46-54
-
-
Johne, A.1
Schmider, J.2
Brockmoller, J.3
Stadelmann, A.M.4
Stormer, E.5
Bauer, S.6
Scholler, G.7
Langheinrich, M.8
Roots, I.9
-
392
-
-
2942625789
-
Effect of St John's wort dose and preparations on the pharmacokinetics of digoxin
-
Mueller S C., Uehleke B, Woehling H, Petzsch M, Majcher-Peszynska J, Hehl E M., Sievers H, Frank B, Riethling A K., Drewelow B. Effect of St John's wort dose and preparations on the pharmacokinetics of digoxin. Clin Pharmacol Ther 2004 75 546-557
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 546-557
-
-
Mueller, S.C.1
Uehleke, B.2
Woehling, H.3
Petzsch, M.4
Majcher-Peszynska, J.5
Hehl, E.M.6
Sievers, H.7
Frank, B.8
Riethling, A.K.9
Drewelow, B.10
-
393
-
-
2442654207
-
The influence of St. John's wort on CYP2C19 activity with respect to genotype
-
Wang L S., Zhu B, El-Aty A M., Zhou G, Li Z, Wu J, Chen G L., Jie L, Tang Z R., Wang A. The influence of St. John's wort on CYP2C19 activity with respect to genotype. J Clin Pharmacol 2004 44 577-581
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 577-581
-
-
Wang, L.S.1
Zhu, B.2
El-Aty, A.M.3
Zhou, G.4
Li, Z.5
Wu, J.6
Chen, G.L.7
Jie, L.8
Tang, Z.R.9
Wang, A.10
-
394
-
-
21844435507
-
Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics
-
Rengelshausen J, Banfield M, Riedel K, Burhenne J, Weiss J, Thomsen T, Walter-Sack I, Haefeli W, Mikus G. Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics. Clin Pharmacol Ther 2005 78 25-33
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 25-33
-
-
Rengelshausen, J.1
Banfield, M.2
Riedel, K.3
Burhenne, J.4
Weiss, J.5
Thomsen, T.6
Walter-Sack, I.7
Haefeli, W.8
Mikus, G.9
-
395
-
-
0042950000
-
Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects
-
Dresser G K., Schwarz U I., Wilkinson G R., Kim R B. Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects. Clin Pharmacol Ther 2005 73 41-50
-
(2005)
Clin Pharmacol Ther
, vol.73
, pp. 41-50
-
-
Dresser, G.K.1
Schwarz, U.I.2
Wilkinson, G.R.3
Kim, R.B.4
-
396
-
-
0036286921
-
Effect of St John's wort on the pharmacokinetics of fexofenadine
-
Wang Z, Hamman M A., Huang S M., Lesko L J., Hall S D. Effect of St John's wort on the pharmacokinetics of fexofenadine. Clin Pharmacol Ther 2002 71 414-420
-
(2002)
Clin Pharmacol Ther
, vol.71
, pp. 414-420
-
-
Wang, Z.1
Hamman, M.A.2
Huang, S.M.3
Lesko, L.J.4
Hall, S.D.5
-
397
-
-
20144389498
-
CYP3A and P-glycoprotein activity induction with St. John's wort in healthy volunteers from 6 ethnic populations
-
Xie R, Tan L H., Polasek E C., Hong C, Teillol-Foo M, Gordi T, Sharma A, Nickens D J., Arakawa T, Knuth D W. CYP3A and P-glycoprotein activity induction with St. John's wort in healthy volunteers from 6 ethnic populations. J Clin Pharmacol 2005 45 352-356
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 352-356
-
-
Xie, R.1
Tan, L.H.2
Polasek, E.C.3
Hong, C.4
Teillol-Foo, M.5
Gordi, T.6
Sharma, A.7
Nickens, D.J.8
Arakawa, T.9
Knuth, D.W.10
-
398
-
-
0035652201
-
Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin
-
Sugimoto K, Ohmori M, Tsuruoka S, Nishiki K, Kawaguchi A, Harada K, Arakawa M, Sakamoto K, Masada M, Miyamori I. Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin. Clin Pharmacol Ther 2001 70 518-524
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 518-524
-
-
Sugimoto, K.1
Ohmori, M.2
Tsuruoka, S.3
Nishiki, K.4
Kawaguchi, A.5
Harada, K.6
Arakawa, M.7
Sakamoto, K.8
Masada, M.9
Miyamori, I.10
-
399
-
-
34548577303
-
Interaction between a commercially available St. John's wort product (Movina) and atorvastatin in patients with hypercholesterolemia
-
Andren L, Andreasson , Eggertsen R. Interaction between a commercially available St. John's wort product (Movina) and atorvastatin in patients with hypercholesterolemia. Eur J Clin Pharmacol 2007 63 913-916
-
(2007)
Eur J Clin Pharmacol
, vol.63
, pp. 913-916
-
-
Andren, L.1
Andreasson2
Eggertsen, R.3
-
400
-
-
0034748331
-
The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity
-
Wang Z, Gorski C, Hamman M A., Huang S-M, Lesko L J., Hall S D. The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity. Clin Pharmacol Ther 2001 70 317-326
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 317-326
-
-
Wang, Z.1
Gorski, C.2
Hamman, M.A.3
Huang, S.-M.4
Lesko, L.J.5
Hall, S.D.6
-
401
-
-
0034695608
-
Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers
-
Markowitz J S., DeVane C L., Boulton D W., Carson S W., Nahas Z, Risch S C. Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers. Life Sci 2000 66 133-139
-
(2000)
Life Sci
, vol.66
, pp. 133-139
-
-
Markowitz, J.S.1
Devane, C.L.2
Boulton, D.W.3
Carson, S.W.4
Nahas, Z.5
Risch, S.C.6
-
402
-
-
0141611906
-
Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme
-
Markowitz J S., Donovan J L., DeVane C L., Taylor R M., Ruan Y, Wang J S., Chavin K D. Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme. JAMA 2003 290 1500-1504
-
(2003)
JAMA
, vol.290
, pp. 1500-1504
-
-
Markowitz, J.S.1
Donovan, J.L.2
Devane, C.L.3
Taylor, R.M.4
Ruan, Y.5
Wang, J.S.6
Chavin, K.D.7
-
403
-
-
4744348755
-
Drug interaction between St John's wort and quazepam
-
Kawaguchi A, Ohmori M, Tsuruoka S-I, Nishiki K, Harada K, Miyamori I, Yano R-I, Nakamura T, Masada M, Fujimura A. Drug interaction between St John's wort and quazepam. Br J Clin Pharmacol 2004 58 403-410
-
(2004)
Br J Clin Pharmacol
, vol.58
, pp. 403-410
-
-
Kawaguchi, A.1
Ohmori, M.2
Tsuruoka, S.-I.3
Nishiki, K.4
Harada, K.5
Miyamori, I.6
Yano, R.-I.7
Nakamura, T.8
Masada, M.9
Fujimura, A.10
-
404
-
-
0035895667
-
Drug interaction between St John's wort and nevirapine
-
de Maat M M., Hoetelmans R M., Math t R A., van Gorp E C., Meenhorst P L., Mulder J W., Beijnen J H. Drug interaction between St John's wort and nevirapine. AIDS 2001 15 420-421
-
(2001)
AIDS
, vol.15
, pp. 420-421
-
-
De Maat, M.M.1
Hoetelmans, R.M.2
Math, T.R.A.3
Van Gorp, E.C.4
Meenhorst, P.L.5
Mulder, J.W.6
Beijnen, J.H.7
-
405
-
-
4544220444
-
St. John's wort reduces oral bioavailability of talinolol in healthy volunteers
-
Schwarz U, Hanso H, Dresser G, Kim R, Fromm M, Oertel R, Miehlke S, Kirch W. St. John's wort reduces oral bioavailability of talinolol in healthy volunteers. Clin Pharmacol Ther 2002 71 P33
-
(2002)
Clin Pharmacol Ther
, vol.71
-
-
Schwarz, U.1
Hanso, H.2
Dresser, G.3
Kim, R.4
Fromm, M.5
Oertel, R.6
Miehlke, S.7
Kirch, W.8
-
406
-
-
1842788672
-
St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism
-
Tannergren C, Engman H, Knutson L, Hedeland M, Bondesson U, Lennernas H. St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism. Clin Pharmacol Ther 2004 75 298-309
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 298-309
-
-
Tannergren, C.1
Engman, H.2
Knutson, L.3
Hedeland, M.4
Bondesson, U.5
Lennernas, H.6
-
407
-
-
0037151365
-
Effects of St. John's wort on irinotecan metabolism
-
Mathijssen R H., Verweij J, de Bruijn P, Loos W J., Sparreboom A. Effects of St. John's wort on irinotecan metabolism. J Natl Cancer Inst 2002 94 1247-1249
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1247-1249
-
-
Mathijssen, R.H.1
Verweij, J.2
De Bruijn, P.3
Loos, W.J.4
Sparreboom, A.5
-
408
-
-
4744338886
-
Effect of St John's wort on imatinib mesylate pharmacokinetics
-
Frye R F., Fitzgerald S M., Lagattuta T F., Hruska M W., Egorin M J. Effect of St John's wort on imatinib mesylate pharmacokinetics. Clin Pharmacol Ther 2004 76 323-329
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 323-329
-
-
Frye, R.F.1
Fitzgerald, S.M.2
Lagattuta, T.F.3
Hruska, M.W.4
Egorin, M.J.5
-
409
-
-
7044245637
-
The influence of St. John's wort on the pharmacokinetics and protein binding of imatinib mesylate
-
Smith P. The influence of St. John's wort on the pharmacokinetics and protein binding of imatinib mesylate. Pharmacotherapy 2004 24 1508-1514
-
(2004)
Pharmacotherapy
, vol.24
, pp. 1508-1514
-
-
Smith, P.1
-
410
-
-
0346874440
-
The interaction between St John's wort and an oral contraceptive
-
Hall S D., Wang Z, Huang S M., Hamman M A., Vasavada N, Adigun A Q., Hilligoss J K., Miller M, Gorski J C. The interaction between St John's wort and an oral contraceptive. Clin Pharmacol Ther 2003 74 525-535
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 525-535
-
-
Hall, S.D.1
Wang, Z.2
Huang, S.M.3
Hamman, M.A.4
Vasavada, N.5
Adigun, A.Q.6
Hilligoss, J.K.7
Miller, M.8
Gorski, J.C.9
-
411
-
-
19444379050
-
Interaction of St. John's Wort with oral contraceptives: Effects on the pharmacokinetics of norethindrone and ethinyl estradiol, ovarian activity and breakthrough bleeding
-
Murphy P A., Kern S E., Stanczyk F Z., Westhoff C L. Interaction of St. John's Wort with oral contraceptives: effects on the pharmacokinetics of norethindrone and ethinyl estradiol, ovarian activity and breakthrough bleeding. Contraception 2005 71 402-408
-
(2005)
Contraception
, vol.71
, pp. 402-408
-
-
Murphy, P.A.1
Kern, S.E.2
Stanczyk, F.Z.3
Westhoff, C.L.4
-
412
-
-
0344081240
-
Interaction of St John's wort with low-dose oral contraceptive therapy: A randomized controlled trial
-
Pfrunder A, Schiesser M, Gerber S, Haschke M, Bitzer J, Drewe J. Interaction of St John's wort with low-dose oral contraceptive therapy: a randomized controlled trial. Br J Clin Pharmacol 2003 56 683-690
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 683-690
-
-
Pfrunder, A.1
Schiesser, M.2
Gerber, S.3
Haschke, M.4
Bitzer, J.5
Drewe, J.6
-
413
-
-
41649113326
-
Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide
-
Xu H, Williams K M., Liauw W S., Murray M, Day R O., McLachlan A J. Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide. Br J Pharmacol 2008 153 1579-1586
-
(2008)
Br J Pharmacol
, vol.153
, pp. 1579-1586
-
-
Xu, H.1
Williams, K.M.2
Liauw, W.S.3
Murray, M.4
Day, R.O.5
McLachlan, A.J.6
-
414
-
-
0033836868
-
Drug interaction between St John's wort and cyclosporine
-
Barone G W., Gurley B J., Ketel B L., Lightfoot M L., Abul-Ezz S R. Drug interaction between St John's wort and cyclosporine. Ann Pharmacother 2000 34 1013-1016
-
(2000)
Ann Pharmacother
, vol.34
, pp. 1013-1016
-
-
Barone, G.W.1
Gurley, B.J.2
Ketel, B.L.3
Lightfoot, M.L.4
Abul-Ezz, S.R.5
-
415
-
-
0035956720
-
Herbal dietary supplements: A source for drug interactions in transplant recipients
-
Barone G W., Gurley B J., Ketel B L., Abul-Ezz S R. Herbal dietary supplements: a source for drug interactions in transplant recipients. Transplantation 2001 71 239-241
-
(2001)
Transplantation
, vol.71
, pp. 239-241
-
-
Barone, G.W.1
Gurley, B.J.2
Ketel, B.L.3
Abul-Ezz, S.R.4
-
416
-
-
10744232730
-
Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients
-
Bauer S, Starmer E, Johne A, Krager H, Budde K, Neumayer H-H, Roots I, Mai I. Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients. Br J Clin Pharmacol 2003 55 203-211
-
(2003)
Br J Clin Pharmacol
, vol.55
, pp. 203-211
-
-
Bauer, S.1
Starmer, E.2
Johne, A.3
Krager, H.4
Budde, K.5
Neumayer, H.-H.6
Roots, I.7
Mai, I.8
-
417
-
-
0037181419
-
Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort
-
Bolley R, Zulke C, Kammerl M, Fischereder M, Kramer B K. Tacrolimus-induced nephrotoxicity unmasked by induction of the CYP3A4 system with St John's wort. Transplantation 2002 73 1009
-
(2002)
Transplantation
, vol.73
, pp. 1009
-
-
Bolley, R.1
Zulke, C.2
Kammerl, M.3
Fischereder, M.4
Kramer, B.K.5
-
418
-
-
0346994708
-
Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteers
-
Hebert M F., Jeong M P., Yu-Luan C, Shahzad A, Anne M L. Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteers. J Clin Pharmacol 2004 44 89-94
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 89-94
-
-
Hebert, M.F.1
Jeong, M.P.2
Yu-Luan, C.3
Shahzad, A.4
Anne, M.L.5
-
419
-
-
0037383772
-
Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients
-
Mai I, Budde K, Starmer E, Bauer S, Krager H, Roots I. Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patients. Nephrol Dial Transplant 2003 18 819-822
-
(2003)
Nephrol Dial Transplant
, vol.18
, pp. 819-822
-
-
Mai, I.1
Budde, K.2
Starmer, E.3
Bauer, S.4
Krager, H.5
Roots, I.6
-
420
-
-
0345074080
-
Methadone maintenance treatment and St. John's wort - A case report
-
Eich-Hochli D, Oppliger R, Golay K P., Baumann P, Eap C B. Methadone maintenance treatment and St. John's wort - a case report. Pharmacopsychiatry 2003 36 35-37
-
(2003)
Pharmacopsychiatry
, vol.36
, pp. 35-37
-
-
Eich-Hochli, D.1
Oppliger, R.2
Golay, K.P.3
Baumann, P.4
Eap, C.B.5
-
421
-
-
12144289727
-
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole
-
Wang L S., Zhou G, Zhu B, Wu J, Wang J G., Abd El-Aty A M., Li T, Liu J, Yang T L., Wang D. St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole. Clin Pharmacol Ther 2004 75 191-197
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 191-197
-
-
Wang, L.S.1
Zhou, G.2
Zhu, B.3
Wu, J.4
Wang, J.G.5
Abd El-Aty, A.M.6
Li, T.7
Liu, J.8
Yang, T.L.9
Wang, D.10
-
422
-
-
59349097187
-
The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men
-
Lundahl A, Hedeland M, Bondesson U, Knutson L, Lennernas H. The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men. Eur J Pharm Sci 2009 36 433-443
-
(2009)
Eur J Pharm Sci
, vol.36
, pp. 433-443
-
-
Lundahl, A.1
Hedeland, M.2
Bondesson, U.3
Knutson, L.4
Lennernas, H.5
|