Time-dependent induction of hepatic cytochrome p450 enzyme activity and mrna expression by bilobalide in rats

Journal of Pharmacological Sciences

Volumn 109, Issue 3, 2009, Pages 459-462

  Taki, Yuko ^a,b   Yamazaki, Yuko ^c   Shimura, Fumio ^c   Yamada, Shizuo ^b   Umegaki, Keizo ^a,c  

^a NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c JUMONJI UNIVERSITY   (Japan)

Author keywords

Bilobalide; Cytochrome P450 (CYP) induction; Herb drug interaction

Indexed keywords

BILOBALIDE; CYTOCHROME P450; GINKGO BILOBA EXTRACT; MESSENGER RNA;

ANIMAL EXPERIMENT; ARTICLE; BIOEQUIVALENCE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG LIVER LEVEL; ENZYME ACTIVITY; ENZYME INDUCTION; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CYCLOPENTANES; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FURANS; GENE EXPRESSION REGULATION; GINKGO BILOBA; GINKGOLIDES; LIVER; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 67249136680     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.08198SC     Document Type: Article

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