The flavanolignan silybin and its hemisynthetic derivatives, a novel series of potential modulators of P-glycoprotein

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 2, 2000, Pages 157-160

  Maitrejean, Mathias ^a   Comte, Gilles ^a   Barron, Denis ^a   El Kirat, Karim ^a   Conseil, Gwenaëlle ^b   Di Pietro, Attilio ^b  

^a UNIVERSITÉ LYON 1   (France)

^b INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

Author keywords

Chemotherapy; Glycoprotein; Natural products; Substituents effects

Indexed keywords

BROMINE DERIVATIVE; FLAVONOID; GLYCOPROTEIN P; SILIBININ;

ALKYLATION; ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0034677063     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00636-8     Document Type: Article

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