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Volumn 304, Issue 3, 2003, Pages 1258-1267

Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AZIDOPINE; BIOCHANIN A; DAUNORUBICIN; DOXORUBICIN; FLAVONOID; GLYCOPROTEIN P; MORIN; PHLORETIN; SILYMARIN;

EID: 0037371275     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.044412     Document Type: Article
Times cited : (329)

References (41)
  • 1
    • 0027417398 scopus 로고
    • Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein
    • al-Shawi MK and Senior AE (1993) Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein. J Biol Chem 268:4197-4206.
    • (1993) J Biol Chem , vol.268 , pp. 4197-4206
    • Al-Shawi, M.K.1    Senior, A.E.2
  • 2
    • 0033972299 scopus 로고    scopus 로고
    • Modulation of liposomal membrane fluidity by flavonoids and isoflavonoids
    • Arora A, Byrem TM, Nair MG, and Strasburg GM (2000) Modulation of liposomal membrane fluidity by flavonoids and isoflavonoids. Arch Biochem Biophys 373: 102-109.
    • (2000) Arch Biochem Biophys , vol.373 , pp. 102-109
    • Arora, A.1    Byrem, T.M.2    Nair, M.G.3    Strasburg, G.M.4
  • 3
    • 0034002720 scopus 로고    scopus 로고
    • Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein
    • Benderra Z, Trussardi A, Morjani H, Villa AM, Doglia SM, and Manfait M (2000) Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein. Eur J Cancer 36:428-434.
    • (2000) Eur J Cancer , vol.36 , pp. 428-434
    • Benderra, Z.1    Trussardi, A.2    Morjani, H.3    Villa, A.M.4    Doglia, S.M.5    Manfait, M.6
  • 4
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
    • Castro AF and Altenberg GA (1997) Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem Pharmacol 53:89-93.
    • (1997) Biochem Pharmacol , vol.53 , pp. 89-93
    • Castro, A.F.1    Altenberg, G.A.2
  • 5
    • 0030041159 scopus 로고    scopus 로고
    • Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3-carbinol
    • Christensen JG and LeBlanc GA (1996) Reversal of multidrug resistance in vivo by dietary administration of the phytochemical indole-3-carbinol. CancerRes 56:574-581.
    • (1996) CancerRes , vol.56 , pp. 574-581
    • Christensen, J.G.1    LeBlanc, G.A.2
  • 7
    • 0032544087 scopus 로고    scopus 로고
    • Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein
    • Conseil G, Baubichon-Cortay H, Dayan G, Jault JM, Barron D, and Di Pietro A (1998) Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein. Proc Natl Acad Sci USA 95:9831-9836.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9831-9836
    • Conseil, G.1    Baubichon-Cortay, H.2    Dayan, G.3    Jault, J.M.4    Barron, D.5    Di Pietro, A.6
  • 8
    • 0028914767 scopus 로고
    • Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability
    • Drori S, Eytan GD, and Assaraf YG (1995) Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability. Eur J Biochem 228:1020-1029.
    • (1995) Eur J Biochem , vol.228 , pp. 1020-1029
    • Drori, S.1    Eytan, G.D.2    Assaraf, Y.G.3
  • 11
    • 0025313475 scopus 로고
    • Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi
    • Fairchild CR, Moscow JA, O'Brien EE, and Cowan KH (1990) Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi. Mol Pharmacol 37:801-809.
    • (1990) Mol Pharmacol , vol.37 , pp. 801-809
    • Fairchild, C.R.1    Moscow, J.A.2    O'Brien, E.E.3    Cowan, K.H.4
  • 12
    • 0025963394 scopus 로고
    • Comparison of the membrane transport of anthracycline derivatives in drug-resistant and drug-sensitive K562 cells
    • Frezard F and Garnier-Suillerot A (1991) Comparison of the membrane transport of anthracycline derivatives in drug-resistant and drug-sensitive K562 cells. Eur J Biochem 196:483-491.
    • (1991) Eur J Biochem , vol.196 , pp. 483-491
    • Frezard, F.1    Garnier-Suillerot, A.2
  • 13
    • 0033514320 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
    • Fromm MF, Kim RB, Stein CM, Wilkinson GR, and Roden DM (1999) Inhibition of P-glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine. Circulation 99:552-557.
    • (1999) Circulation , vol.99 , pp. 552-557
    • Fromm, M.F.1    Kim, R.B.2    Stein, C.M.3    Wilkinson, G.R.4    Roden, D.M.5
  • 14
    • 0029954843 scopus 로고    scopus 로고
    • P-glycoprotein: A mediator of multidrug resistance in tumour cells
    • Germann UA (1996) P-glycoprotein: a mediator of multidrug resistance in tumour cells. Eur J Cancer 32A:927-944.
    • (1996) Eur J Cancer , vol.32 A , pp. 927-944
    • Germann, U.A.1
  • 15
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM and Pastan I (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 17
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL and Ling V (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 455:152-162.
    • (1976) Biochim Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 18
    • 0020578356 scopus 로고
    • Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines
    • Kartner N, Riordan JR, and Ling V (1983) Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science (Wash DC) 221:1285-1288.
    • (1983) Science (Wash DC) , vol.221 , pp. 1285-1288
    • Kartner, N.1    Riordan, J.R.2    Ling, V.3
  • 19
    • 0033785929 scopus 로고    scopus 로고
    • Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats
    • Kiso S, Cai SH, Kitaichi K, Furui N, Takagi K, Nabeshima T, and Hasegawa T (2000) Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats. Anticancer Res 20:2827-2834.
    • (2000) Anticancer Res , vol.20 , pp. 2827-2834
    • Kiso, S.1    Cai, S.H.2    Kitaichi, K.3    Furui, N.4    Takagi, K.5    Nabeshima, T.6    Hasegawa, T.7
  • 20
    • 0016906546 scopus 로고
    • The flavonoids. A class of semi-essential food components: Their role in human nutrition
    • Kuhnau J (1976) The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet 24:117-191.
    • (1976) World Rev Nutr Diet , vol.24 , pp. 117-191
    • Kuhnau, J.1
  • 22
    • 0030058445 scopus 로고    scopus 로고
    • Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia
    • List AF (1996) Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia. Leukemia 10:937-942.
    • (1996) Leukemia , vol.10 , pp. 937-942
    • List, A.F.1
  • 23
    • 0030781139 scopus 로고    scopus 로고
    • Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833
    • Mayer U, Wagenaar E, Dorobek B, Beijnen JH, Borst P, and Schinkel AH (1997) Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. J Clin Invest 100: 2430-2436.
    • (1997) J Clin Invest , vol.100 , pp. 2430-2436
    • Mayer, U.1    Wagenaar, E.2    Dorobek, B.3    Beijnen, J.H.4    Borst, P.5    Schinkel, A.H.6
  • 24
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease and cancer
    • Middleton E Jr, Kandaswami C, and Theoharides TC (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer. Pharmacol Rev 52:673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton E., Jr.1    Kandaswami, C.2    Theoharides, T.C.3
  • 25
    • 0036549375 scopus 로고    scopus 로고
    • Utilization of complementary and alternative medicine by United States adults: Results from the 1999 national health interview survey
    • Ni H, Simile C, and Hardy AM (2002) Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey. Med Care 40:353-358.
    • (2002) Med Care , vol.40 , pp. 353-358
    • Ni, H.1    Simile, C.2    Hardy, A.M.3
  • 26
    • 0028269030 scopus 로고
    • Clinical relevance of P-glycoprotein expression in haematological malignancies
    • Nooter K and Sonneveld P (1994) Clinical relevance of P-glycoprotein expression in haematological malignancies. Leukoc Res 18:233-243.
    • (1994) Leukoc Res , vol.18 , pp. 233-243
    • Nooter, K.1    Sonneveld, P.2
  • 29
    • 0031982725 scopus 로고    scopus 로고
    • Pharmacological insights from P-glycoprotein knockout mice
    • Schinkel AH (1998) Pharmacological insights from P-glycoprotein knockout mice. Int J Clin Pharmacol Ther 36:9-13.
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 9-13
    • Schinkel, A.H.1
  • 30
    • 0033083015 scopus 로고    scopus 로고
    • Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site
    • Shapiro AB, Fox K, Lam P, and Ling V (1999) Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site. Eur J Biochem 259:841-850.
    • (1999) Eur J Biochem , vol.259 , pp. 841-850
    • Shapiro, A.B.1    Fox, K.2    Lam, P.3    Ling, V.4
  • 31
    • 0027937143 scopus 로고
    • ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells
    • Shapiro AB and Ling V (1994) ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells. J Biol Chem 269:3745-3754.
    • (1994) J Biol Chem , vol.269 , pp. 3745-3754
    • Shapiro, A.B.1    Ling, V.2
  • 32
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
    • Shapiro AB and Ling V (1997a) Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem Pharmacol 53:587-596.
    • (1997) Biochem Pharmacol , vol.53 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 33
    • 0030782511 scopus 로고    scopus 로고
    • Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
    • Shapiro AB and Ling V (1997b) Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur J Biochem 250:130-137.
    • (1997) Eur J Biochem , vol.250 , pp. 130-137
    • Shapiro, A.B.1    Ling, V.2
  • 35
    • 0033051587 scopus 로고    scopus 로고
    • Effect of PSC 833, a P-glycoprotein modulator, on the disposition of vincristine and digoxin in rats
    • Song S, Suzuki H, Kawai R, and Sugiyama Y (1999) Effect of PSC 833, a P-glycoprotein modulator, on the disposition of vincristine and digoxin in rats. Drug Metab Dispos 27:689-694.
    • (1999) Drug Metab Dispos , vol.27 , pp. 689-694
    • Song, S.1    Suzuki, H.2    Kawai, R.3    Sugiyama, Y.4
  • 36
    • 0025991731 scopus 로고
    • Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells
    • Tamai I and Safa AR (1991) Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells. J Biol Chem 266:16796-16800.
    • (1991) J Biol Chem , vol.266 , pp. 16796-16800
    • Tamai, I.1    Safa, A.R.2
  • 37
    • 0013400069 scopus 로고    scopus 로고
    • Effect of flavonoids on P-glycoprotein-mediated transport in a human breast cancer cell line
    • Poster presentation at the Annual Meeting of the American Association of Pharmaceutical Scientists, October 21-25, 2001, Denver CO
    • Tseng E, Liang W, and Morris ME (2001) Effect of flavonoids on P-glycoprotein-mediated transport in a human breast cancer cell line, Poster presentation at the Annual Meeting of the American Association of Pharmaceutical Scientists, October 21-25, 2001, Denver CO. Pharm Res 3.
    • (2001) Pharm Res , vol.3
    • Tseng, E.1    Liang, W.2    Morris, M.E.3
  • 38
    • 0019430432 scopus 로고
    • Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
    • Tsuruo T, Iida H, Tsukagoshi S, and Sakurai Y (1981) Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res 41:1967-1972.
    • (1981) Cancer Res , vol.41 , pp. 1967-1972
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 39
    • 0029124166 scopus 로고
    • P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site
    • Urbatsch IL, Sankaran B, Weber J, and Senior AE (1995) P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site. J Biol Chem 270:19383-19390.
    • (1995) J Biol Chem , vol.270 , pp. 19383-19390
    • Urbatsch, I.L.1    Sankaran, B.2    Weber, J.3    Senior, A.E.4
  • 40
    • 0031843013 scopus 로고    scopus 로고
    • Multidrug resistance and its reversal
    • Volm M (1998) Multidrug resistance and its reversal. Anticancer Res 18:2905-2917.
    • (1998) Anticancer Res , vol.18 , pp. 2905-2917
    • Volm, M.1
  • 41
    • 0033328139 scopus 로고    scopus 로고
    • The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions
    • Yu DK (1999) The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions. J Clin Pharmacol 39:1203-1211.
    • (1999) J Clin Pharmacol , vol.39 , pp. 1203-1211
    • Yu, D.K.1


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