Piperine impairs cytochrome P4501A1 activity by direct interaction with the enzyme and not by down regulation of CYP1A1 gene expression in the rat hepatoma 5L cell line

Biochemical and Biophysical Research Communications

Volumn 218, Issue 2, 1996, Pages 562-569

  Reen, Rashmeet K ^a   Roesch, Siegfried F ^b   Kiefer, Franz ^b   Wiebel, Friedrich J ^b   Singh, Jaswant ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE; BENZ[A]ANTHRACENE; CYTOCHROME P450; MESSENGER RNA; PIPERINE; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME REGULATION; GENE ACTIVATION; HEPATOMA CELL; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSCRIPTION REGULATION;

EID: 0029671233     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.0100     Document Type: Article

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