Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of schisandra chinensis through nuclear accumulation of Nrf2

Planta Medica

Volumn 75, Issue 12, 2009, Pages 1314-1318

  Lee, Saet Byoul ^a   Young Kim, Chul ^a   Ju Lee, Hee ^a   Ho Yun, Ji ^a   Nho, Chu Won ^a  

^a Korea Institute of Science and Technology   (South Korea)

Author keywords

Magnoliaceae; Nrf2; Quinone reductase; Schisandra chinensis baillon; Tigloylgomisin H

Indexed keywords

ANGELOYLGOMISIN H; HYPOXIA INDUCIBLE FACTOR 1BETA; LIGNAN DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SCHISANDRA CHINENSIS EXTRACT; TIGLOYLGOMISIN H; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BIOACCUMULATION; CANCER CELL CULTURE; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; ISOLATION PROCEDURE; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN FUNCTION; UPREGULATION;

ANIMALS; ANTICARCINOGENIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; FRUIT; HUMANS; LIGNANS; LIVER NEOPLASMS; METABOLIC DETOXICATION, PHASE II; MICE; NAD(P)H DEHYDROGENASE (QUINONE); NADPH DEHYDROGENASE; NF-E2-RELATED FACTOR 2; SCHISANDRA;

MAGNOLIACEAE; SCHISANDRA CHINENSIS;

EID: 70449379202     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185685     Document Type: Article

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