Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells

Pharmaceutical Research

Volumn 20, Issue 8, 2003, Pages 1184-1191

  Zhang, Shuzhong ^a   Morris, Marilyn E ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Biochanin A; Drug bioavailability; Intestinal transport; P glycoprotein; Silymarin

Indexed keywords

BIOCHANIN A; DIGOXIN; FLAVONOID; GLYCOPROTEIN P; SILYMARIN; VERAPAMIL; VINBLASTINE;

ARTICLE; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; PRIORITY JOURNAL;

BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CACO-2 CELLS; DIGOXIN; DRUG INTERACTIONS; GENISTEIN; HUMANS; INTESTINAL ABSORPTION; P-GLYCOPROTEIN; SILYMARIN; VINBLASTINE;

EID: 0043127383     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025044913766     Document Type: Article

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