St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4

Clinical Pharmacology and Therapeutics

Volumn 68, Issue 6, 2000, Pages 598-604

  Dürr, Donat ^a   Stieger, Bruno ^a   Kullak Ublick, Gerd A ^a   Rentsch, Katharina M ^a   Steinert, Hans C ^a   Meier, Peter J ^a   Fattinger, Karin ^a  

^a Department of Cardiology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; CYTOCHROME P450 3A4; DIGITOXIN; GLYCOPROTEIN P; INDINAVIR;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BREATH ANALYSIS; CONTROLLED STUDY; DEPRESSION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG EFFICACY; DRUG EXPOSURE; HUMAN; HUMAN EXPERIMENT; HYPERICUM PERFORATUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ADULT; ANIMALS; BIOLOGICAL AVAILABILITY; CARDIOTONIC AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; DIGOXIN; DRUG INTERACTIONS; DUODENUM; ENZYME INDUCTION; HUMANS; HYPERICUM; INTESTINE, SMALL; LIVER; MALE; MIXED FUNCTION OXYGENASES; P-GLYCOPROTEIN; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034520267     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2000.112240     Document Type: Article

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