Possible differential induction of phase 2 enzyme and antioxidant pathways by American ginseng, Panax quinquefolius

Journal of Clinical Pharmacology

Volumn 48, Issue 5, 2008, Pages 599-609

  Lee, Lawrence S ^a   Wise, Stephen D ^c   Chan, Clark ^c   Parsons, Teresa L ^a   Flexner, Charles ^a,b   Lietman, Paul S ^a,b,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NONE   (United States)

Author keywords

Ginseng; Oxidative stress; Uridine diphosphate glucuronosyltransferase; Zidovudine

Indexed keywords

GINSENG EXTRACT; GUANOSINE; HT 1001; HYDROXYDEOXYGUANOSINE; ISOPROSTANE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG; ZIDOVUDINE;

ADULT; AGED; ANTIOXIDANT ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; GINSENG; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; OXIDATIVE STRESS; PANAX QUINQUEFOLIUS; SINGLE DRUG DOSE;

ANTI-HIV AGENTS; ANTIOXIDANTS; AREA UNDER CURVE; BIOMARKERS, PHARMACOLOGICAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; F2-ISOPROSTANES; FEMALE; GINSENOSIDES; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HUMANS; MALE; METABOLIC CLEARANCE RATE; NAD(P)H DEHYDROGENASE (QUINONE); OXIDATIVE STRESS; PANAX; PHYTOTHERAPY; PLANT EXTRACTS; ZIDOVUDINE;

EID: 41849106806     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270008314252     Document Type: Article

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