Metabolomic profiling of liquid echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4)

Planta Medica

Volumn 76, Issue 4, 2010, Pages 378-385

  Modarai, Maryam ^a   Yang, Min ^a   Suter, Andy ^b   Kortenkamp, Andreas ^a   Heinrich, Michael ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Bioforce AG   (Switzerland)

Author keywords

Alkylamides; Asteraceae (Compositae); Cytochrome P450 enzymes; Echinacea; Herbdrug interactions; Metabolomics

Indexed keywords

ACETYLENE; AMIDE; CYTOCHROME P450 3A4; ECHINACEA PALLIDA EXTRACT; ECHINACEA PURPUREA EXTRACT; ECHINAFORCE; ECHINAGOLD; HOLLAND AND BARRETT; KETOCONAZOLE; MADAUS; SALUS; UNCLASSIFIED DRUG; VIRIDIAN;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; IN VITRO STUDY; LIQUID; LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; METABOLISM; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITY CONTROL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

ALKYNES; AMIDES; COMMERCE; CYTOCHROME P-450 CYP3A; ECHINACEA; FATTY ACIDS, UNSATURATED; HERB-DRUG INTERACTIONS; METABOLOME; METABOLOMICS; PLANT EXTRACTS;

ASTERACEAE; ECHINACEA (ASTERACEAE); ECHINACEA PALLIDA; ECHINACEA PURPUREA;

EID: 77749308316     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1186152     Document Type: Article

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