Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction

Journal of Food Science

Volumn 75, Issue 3, 2010, Pages

  Jin, Ming Ji ^a   Han, Hyo Kyung ^a  

^a Chosun University   (South Korea)

Author keywords

Absorption; Fexofenadine; Food drug interaction; P glycoprotein; Piperine

Indexed keywords

1,3 BENZODIOXOLE DERIVATIVE; ALKALOID; AMIDE; DRUG DERIVATIVE; ENZYME INHIBITOR; FEXOFENADINE; GLYCOPROTEIN P; HISTAMINE H1 RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE; PIPERINE; TERFENADINE; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL; ARTICLE; BIOAVAILABILITY; BLACK PEPPER; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; FOOD DRUG INTERACTION; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; MALE; RAT; SPRAGUE DAWLEY RAT; STOMACH EMPTYING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS;

ALKALOIDS; ANIMALS; BENZODIOXOLES; BIOLOGICAL AVAILABILITY; BLACK PEPPER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; FOOD-DRUG INTERACTIONS; GASTRIC EMPTYING; HALF-LIFE; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; INTESTINAL ABSORPTION; MALE; P-GLYCOPROTEIN; PIPERIDINES; POLYUNSATURATED ALKAMIDES; RATS; RATS, SPRAGUE-DAWLEY; TERFENADINE;

PIPER NIGRUM; RATTUS;

EID: 77953907984     PISSN: 00221147     EISSN: 17503841     Source Type: Journal    
DOI: 10.1111/j.1750-3841.2010.01542.x     Document Type: Article

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