The potent protective effect of wild ginseng (Panax ginseng C.A. Meyer) against benzo[α]pyrene-induced toxicity through metabolic regulation of CYP1A1 and GSTs

Journal of Ethnopharmacology

Volumn 112, Issue 3, 2007, Pages 568-576

  Gum, Sang Il ^a   Jo, Sung Jun ^a   Ahn, Sang Hyun ^a   Kim, Sang Geon ^b   Kim, Jin Taek ^a   Shin, Heung Mook ^a   Cho, Min Kyung ^a  

^a Dongguk University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Benzo pyrene; CYP1A1; GST; Hepatoprotection; Wild ginseng

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 1A1; GINSENG EXTRACT; GLUTATHIONE TRANSFERASE; LIPID PEROXIDASE; MESSENGER RNA; QUINOXALINE; TRANSCRIPTION FACTOR NRF2;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CULTURE MEDIUM; DISEASE MODEL; DISEASE SEVERITY; DRUG EFFECT; DRUG POTENCY; GENE; GENE EXPRESSION PROFILING; GINSENG; GSTA2 GENE; GSTA3 GENE; GSTM2 GENE; HISTOPATHOLOGY; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; NONHUMAN; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BENZO(A)PYRENE; BLOTTING, WESTERN; CELL LINE; CYTOCHROME P-450 CYP1A1; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; INJECTIONS, INTRAPERITONEAL; ISOENZYMES; LIPID PEROXIDATION; LIVER; LIVER DISEASES; METABOLIC NETWORKS AND PATHWAYS; PANAX; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

PANAX GINSENG; RATTUS;

EID: 34347346161     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2007.05.014     Document Type: Article

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