Interaction of St. John's Wort with oral contraceptives: Effects on the pharmacokinetics of norethindrone and ethinyl estradiol, ovarian activity and breakthrough bleeding

Contraception

Volumn 71, Issue 6, 2005, Pages 402-408

  Murphy, Patricia A ^a   Kern, Steven E ^b   Stanczyk, Frank Z ^c   Westhoff, Carolyn L ^d  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d NONE   (United States)

Author keywords

Drug interactions; Ethinyl estradiol; Hypericum perforatum; Norethindrone; Oral contraceptives; Pharmacokinetics; St. John's Wort

Indexed keywords

ETHINYLESTRADIOL PLUS NORETHISTERONE ACETATE; HERBACEOUS AGENT; HYPERICUM PERFORATUM EXTRACT; ORAL CONTRACEPTIVE AGENT; PLACEBO; PROGESTERONE;

ADULT; ARTICLE; BREAKTHROUGH BLEEDING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EXPOSURE; DRUG METABOLISM; DRUG SCREENING; FEMALE; HUMAN; HUMAN EXPERIMENT; LOW DRUG DOSE; NORMAL HUMAN; OUTCOMES RESEARCH; OVARY; OVARY FOLLICLE; OVULATION; SINGLE BLIND PROCEDURE; UTERINE CERVIX MUCOSA;

ADULT; CONTRACEPTIVES, ORAL, SYNTHETIC; DRUG INTERACTIONS; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; HERB-DRUG INTERACTIONS; HUMANS; HYPERICUM; METRORRHAGIA; NORETHINDRONE; OVULATION;

EID: 19444379050     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2004.11.004     Document Type: Article

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