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Volumn 56, Issue 16, 2016, Pages 2747-2766

Mechanisms Linking Colorectal Cancer to the Consumption of (Processed) Red Meat: A Review

Author keywords

heme; heterocyclic aromatic amines; lipid oxidation; N glycolylneuraminic acid; N nitroso compounds; Polycyclic aromatic hydrocarbons

Indexed keywords

AMINES; AROMATIC COMPOUNDS; AROMATIC HYDROCARBONS; AROMATIZATION; HYDROCARBONS; MEATS; NITROGEN COMPOUNDS; ORGANIC COMPOUNDS; POLYCYCLIC AROMATIC HYDROCARBONS; PORPHYRINS;

EID: 84983086236     PISSN: 10408398     EISSN: 15497852     Source Type: Journal    
DOI: 10.1080/10408398.2013.873886     Document Type: Article
Times cited : (143)

References (230)
  • 1
    • 79954987925 scopus 로고    scopus 로고
    • Factors that affect the content of heterocyclic aromatic amines in foods
    • M.S.Alaejos, and A.M.Afonso, (2011). Factors that affect the content of heterocyclic aromatic amines in foods. CRFSFS 10:52–108.
    • (2011) CRFSFS , vol.10 , pp. 52-108
    • Alaejos, M.S.1    Afonso, A.M.2
  • 2
    • 36749039697 scopus 로고    scopus 로고
    • Exposure to heterocyclic aromatic amines from the consumption of cooked red meat and its effect on human cancer risk: A review
    • M.S.Alaejos, V.González, and A.M.Afonso, (2007). Exposure to heterocyclic aromatic amines from the consumption of cooked red meat and its effect on human cancer risk:A review. Food Addit. Contam. Part A 25:2–24.
    • (2007) Food Addit. Contam. Part A , vol.25 , pp. 2-24
    • Alaejos, M.S.1    González, V.2    Afonso, A.M.3
  • 7
    • 0031408811 scopus 로고    scopus 로고
    • Assessment of the human exposure to heterocyclic amines
    • K.Augustsson, K.Skog, M.Jägerstad, and G.Teineck, (1997). Assessment of the human exposure to heterocyclic amines. Carcinogenesis 18:1931–1935.
    • (1997) Carcinogenesis , vol.18 , pp. 1931-1935
    • Augustsson, K.1    Skog, K.2    Jägerstad, M.3    Teineck, G.4
  • 9
    • 0037014283 scopus 로고    scopus 로고
    • Myoglobin-induced lipid oxidation. A review
    • C.P.Baron, and H.J.Andersen, (2002). Myoglobin-induced lipid oxidation. A review. J. Agric. Food Chem. 50:3887–3897.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 3887-3897
    • Baron, C.P.1    Andersen, H.J.2
  • 10
    • 9644294192 scopus 로고    scopus 로고
    • Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis
    • H.Bartsch, and J.Nair, (2004). Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis. Cancer Detect. Prev. 28:385–391.
    • (2004) Cancer Detect. Prev. , vol.28 , pp. 385-391
    • Bartsch, H.1    Nair, J.2
  • 11
    • 79551690942 scopus 로고    scopus 로고
    • Heme iron from meat and risk of colorectal cancer: A meta-analysis and a review of the mechanisms involved
    • N.M.Bastide, F.H.F.Pierre, and D.E.Corpet, (2011). Heme iron from meat and risk of colorectal cancer:A meta-analysis and a review of the mechanisms involved. CAPR 4:177–184.
    • (2011) CAPR , vol.4 , pp. 177-184
    • Bastide, N.M.1    Pierre, F.H.F.2    Corpet, D.E.3
  • 12
    • 0020615703 scopus 로고
    • Unequivocal demonstration that malondialdehyde is a mutagen
    • A.K.Basu, and L.J.Marnett, (1983). Unequivocal demonstration that malondialdehyde is a mutagen. Carcinogenesis 4:331–333.
    • (1983) Carcinogenesis , vol.4 , pp. 331-333
    • Basu, A.K.1    Marnett, L.J.2
  • 13
    • 78649365835 scopus 로고    scopus 로고
    • Chronic inflammation, colorectal cancer and gene polymorphisms
    • C.R.Boland, (2010). Chronic inflammation, colorectal cancer and gene polymorphisms. Dig. Dis. 28:590–595.
    • (2010) Dig. Dis. , vol.28 , pp. 590-595
    • Boland, C.R.1
  • 14
    • 77449130761 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer
    • C.R.Boland, and A.Goel, (2010). Microsatellite instability in colorectal cancer. Gastroenterology 138:2073–2087.
    • (2010) Gastroenterology , vol.138 , pp. 2073-2087
    • Boland, C.R.1    Goel, A.2
  • 15
    • 84862116034 scopus 로고    scopus 로고
    • Gut bacteria in health and disease: A survey on the interface between intestinal microbiology and colorectal cancer
    • A.Boleij, and H.Tjalsma, (2012). Gut bacteria in health and disease:A survey on the interface between intestinal microbiology and colorectal cancer. Biol. Rev. 87:701–730.
    • (2012) Biol. Rev. , vol.87 , pp. 701-730
    • Boleij, A.1    Tjalsma, H.2
  • 16
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • J.L.Bos, (1989). Ras oncogenes in human cancer:A review. Cancer Res. 49:4682–4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 17
    • 53049093042 scopus 로고    scopus 로고
    • Diet, nutrition and cancer: Public, media and scientific confusion
    • P.Boyle, P.Boffetta, and P.Autier, (2008). Diet, nutrition and cancer:Public, media and scientific confusion. Ann. Oncol. 19:1665–1667.
    • (2008) Ann. Oncol. , vol.19 , pp. 1665-1667
    • Boyle, P.1    Boffetta, P.2    Autier, P.3
  • 18
    • 0021857968 scopus 로고
    • Descriptive epidemiology of colorectal cancer
    • P.Boyle, D.Zaridze, and M.Smans, (1985). Descriptive epidemiology of colorectal cancer. Int. J. Cancer 36:9–18.
    • (1985) Int. J. Cancer , vol.36 , pp. 9-18
    • Boyle, P.1    Zaridze, D.2    Smans, M.3
  • 19
    • 0023220755 scopus 로고
    • Recent hypotheses for the origin of colon cancer
    • W.R.Bruce, (1987). Recent hypotheses for the origin of colon cancer. Cancer Res. 47:4237–4242.
    • (1987) Cancer Res , vol.47 , pp. 4237-4242
    • Bruce, W.R.1
  • 21
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • E.E.Calle, and R.Kaaks, (2004). Overweight, obesity and cancer:Epidemiological evidence and proposed mechanisms. Nat. Rev. Cancer 4:579–591.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 24
    • 84983069235 scopus 로고    scopus 로고
    • Available from
    • CFR. (2012). 21 CFR:Food and Drugs. Available from http://www.gpo.gov/fdsys/pkg/CFR-2012-title21-vol3/pdf/CFR-2012-title21-vol3.pdf. Accessed October 21, 2013.
    • (2012) 21 CFR: Food and Drugs
  • 25
    • 79958157809 scopus 로고    scopus 로고
    • Red and processed meat and colorectal cancer incidence: Meta-analysis of prospective studies
    • D.S.M.Chan, R.Lau, D.Aune, R.Vieira, D.C.Greenwood, E.Kampman, and T.Norat, (2011). Red and processed meat and colorectal cancer incidence:Meta-analysis of prospective studies. PLoS ONE 6:e20456.
    • (2011) PLoS ONE , vol.6 , pp. e20456
    • Chan, D.S.M.1    Lau, R.2    Aune, D.3    Vieira, R.4    Greenwood, D.C.5    Kampman, E.6    Norat, T.7
  • 26
    • 84874622887 scopus 로고    scopus 로고
    • Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite
    • F.Z.Chenni, S.Taché, N.Naud, F.Guéraud, D.A.Hobbs, G.G.C.Kunhle, F.H.Pierre, and D.E.Corpet, (2013). Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite. Nutr. Cancer 65:227–233.
    • (2013) Nutr. Cancer , vol.65 , pp. 227-233
    • Chenni, F.Z.1    Taché, S.2    Naud, N.3    Guéraud, F.4    Hobbs, D.A.5    Kunhle, G.G.C.6    Pierre, F.H.7    Corpet, D.E.8
  • 30
    • 79960441685 scopus 로고    scopus 로고
    • Red meat and colon cancer: Should we become vegetarians, or can we make meat safer?
    • D.E.Corpet, (2011). Red meat and colon cancer:Should we become vegetarians, or can we make meat safer? Meat Sci. 89:310–316.
    • (2011) Meat Sci , vol.89 , pp. 310-316
    • Corpet, D.E.1
  • 32
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • L.M.Coussens, and Z.Werb, (2002). Inflammation and cancer. Nature 420:860–867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 33
    • 77950215241 scopus 로고    scopus 로고
    • A large prospective study of meat consumption and colorectal cancer risk: An investigation of potential mechanisms underlying this association
    • A.J.Cross, L.M.Ferrucci, A.Risch, B.I.Graubard, M.H.Ward, Y.Park, A.R.Hollenbeck, A.Schatzkin, and R.Sinha, (2010). A large prospective study of meat consumption and colorectal cancer risk:An investigation of potential mechanisms underlying this association. Cancer Res. 70:2406–2414.
    • (2010) Cancer Res. , vol.70 , pp. 2406-2414
    • Cross, A.J.1    Ferrucci, L.M.2    Risch, A.3    Graubard, B.I.4    Ward, M.H.5    Park, Y.6    Hollenbeck, A.R.7    Schatzkin, A.8    Sinha, R.9
  • 34
    • 33645531207 scopus 로고    scopus 로고
    • Variability in fecal water genotoxicity, determined using the Comet assay, is independent of endogenous N-Nitroso compound formation attributed to red meat consumption
    • A.J.Cross, H.L.Greetham, J.R.A.Pollock, I.R.Rowland, and S.A.Bingham, (2006). Variability in fecal water genotoxicity, determined using the Comet assay, is independent of endogenous N-Nitroso compound formation attributed to red meat consumption. Environ. Mol. Mutagen. 47:179–184.
    • (2006) Environ. Mol. Mutagen. , vol.47 , pp. 179-184
    • Cross, A.J.1    Greetham, H.L.2    Pollock, J.R.A.3    Rowland, I.R.4    Bingham, S.A.5
  • 35
    • 3242794269 scopus 로고    scopus 로고
    • Meat-related mutagens/carcinogens in the etiology of colorectal cancer
    • A.J.Cross, and R.Sinha, (2004). Meat-related mutagens/carcinogens in the etiology of colorectal cancer. Environ. Mol. Mutagen. 44:44–55.
    • (2004) Environ. Mol. Mutagen. , vol.44 , pp. 44-55
    • Cross, A.J.1    Sinha, R.2
  • 36
    • 34548305190 scopus 로고    scopus 로고
    • Investigations on selected essential micronutrients in muscle of german pure and crossbred pigs
    • D.Dannenberger, W.Reichardt, J.Danier, G.Numberg, and K.Ender, (2007). Investigations on selected essential micronutrients in muscle of german pure and crossbred pigs. Fleischwirtschaft 87:90–93.
    • (2007) Fleischwirtschaft , vol.87 , pp. 90-93
    • Dannenberger, D.1    Reichardt, W.2    Danier, J.3    Numberg, G.4    Ender, K.5
  • 38
    • 0034212585 scopus 로고    scopus 로고
    • Evaluation of fecal mutagenicity and colorectal cancer risk
    • T.M.C.M.de Kok, and J.M.S.van Maanen, (2000). Evaluation of fecal mutagenicity and colorectal cancer risk. Mutat. Res-Rev. Mutat. 463:53–101.
    • (2000) Mutat. Res-Rev. Mutat. , vol.463 , pp. 53-101
    • de Kok, T.M.C.M.1    van Maanen, J.M.S.2
  • 40
    • 52249117007 scopus 로고    scopus 로고
    • The World Cancer Research Fund report 2007: A challenge for the meat processing industry
    • D.Demeyer, K.Honikel, and S.De Smet, (2008). The World Cancer Research Fund report 2007:A challenge for the meat processing industry. Meat Sci. 80:953–959.
    • (2008) Meat Sci , vol.80 , pp. 953-959
    • Demeyer, D.1    Honikel, K.2    De Smet, S.3
  • 41
    • 84863994276 scopus 로고    scopus 로고
    • Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP)
    • N.C.Deziel, T.J.Buckley, R.Sinha, S.Abubaker, E.A.Platz, and P.T.Strickland, (2012). Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP). Food Addit. Contam. Part A; 29:1202–1211.
    • (2012) Food Addit. Contam. Part A , vol.29 , pp. 1202-1211
    • Deziel, N.C.1    Buckley, T.J.2    Sinha, R.3    Abubaker, S.4    Platz, E.A.5    Strickland, P.T.6
  • 43
    • 84859607821 scopus 로고    scopus 로고
    • Response surface optimization of effects of some processing variables on carcinogenic/mutagenic heterocyclic aromatic amine (HAA) content in cooked patties
    • A.Dundar, C.Sançoban, and M.T.Yilmaz, (2012). Response surface optimization of effects of some processing variables on carcinogenic/mutagenic heterocyclic aromatic amine (HAA) content in cooked patties. Meat Sci. 91:325–333.
    • (2012) Meat Sci , vol.91 , pp. 325-333
    • Dundar, A.1    Sançoban, C.2    Yilmaz, M.T.3
  • 46
    • 84055213129 scopus 로고    scopus 로고
    • Secondary targets of nitrite-derived reactive nitrogen species: Nitrosation/nitration pathways, antioxidant defense mechanisms and toxicological implications
    • M.d’Ischia, A.Napolitano, P.Manini, and L.Panzella, (2011). Secondary targets of nitrite-derived reactive nitrogen species:Nitrosation/nitration pathways, antioxidant defense mechanisms and toxicological implications. Chem. Res. Toxicol. 24:2071–2092.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 2071-2092
    • d’Ischia, M.1    Napolitano, A.2    Manini, P.3    Panzella, L.4
  • 48
    • 84873206778 scopus 로고    scopus 로고
    • Intestinal formation of N-nitroso compounds in the pig cecum model
    • A.Engemann, C.Focke, and H.U.Humpf, (2013). Intestinal formation of N-nitroso compounds in the pig cecum model. J. Agric. Food Chem. 61:998–1005.
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 998-1005
    • Engemann, A.1    Focke, C.2    Humpf, H.U.3
  • 52
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • E.R.Fearon, and B.Vogelstein, (1990). A genetic model for colorectal tumorigenesis. Cell 61:759–767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 54
    • 84983066526 scopus 로고    scopus 로고
    • Available from
    • FOD economie. (2010). Prijzen, kosten en rendabiliteit in de varkenskolom. Available from http://economie.fgov.be/nl/binaries/studyporcnltcm325–73348.pdf. Accessed August 15, 2013.
    • (2010) Prijzen, kosten en rendabiliteit in de varkenskolom
  • 56
    • 78651269402 scopus 로고    scopus 로고
    • The Mediterranean and dietary approaches to stop hypertension (DASH) diets and colorectal cancer
    • T.T.Fung, F.B.Hu, K.Wu, S.E.Chiuve, C.S.Fuchs, and E.Giovannucci, (2010). The Mediterranean and dietary approaches to stop hypertension (DASH) diets and colorectal cancer. Am. J. Clin. Nutr. 92:1429–1435.
    • (2010) Am. J. Clin. Nutr. , vol.92 , pp. 1429-1435
    • Fung, T.T.1    Hu, F.B.2    Wu, K.3    Chiuve, S.E.4    Fuchs, C.S.5    Giovannucci, E.6
  • 57
    • 80053922824 scopus 로고    scopus 로고
    • Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type
    • Z.Fu, M.J.Shrubsole, W.E.Smalley, H.Wu, Z.Chen, Y.Shyr, R.M.Ness, and W.Zheng, (2011). Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type. CAPR 4:1686–1697.
    • (2011) CAPR , vol.4 , pp. 1686-1697
    • Fu, Z.1    Shrubsole, M.J.2    Smalley, W.E.3    Wu, H.4    Chen, Z.5    Shyr, Y.6    Ness, R.M.7    Zheng, W.8
  • 58
    • 0036894158 scopus 로고    scopus 로고
    • Hormones in international meat production: Biological, sociological and consumer issues
    • H.Galbraith, (2002). Hormones in international meat production:Biological, sociological and consumer issues. Nutr. Res. Rev. 15:293–314.
    • (2002) Nutr. Res. Rev. , vol.15 , pp. 293-314
    • Galbraith, H.1
  • 60
    • 57649140387 scopus 로고    scopus 로고
    • Variability of selected trace elements of different meat cuts determined by ICP-MS and DRC-ICPMS
    • N.Gerber, R.Brogioli, B.Hattendorf, M.R.Scheeder, C.Wenk, and D.Gunther, (2009). Variability of selected trace elements of different meat cuts determined by ICP-MS and DRC-ICPMS. Animal 3:166–172.
    • (2009) Animal , vol.3 , pp. 166-172
    • Gerber, N.1    Brogioli, R.2    Hattendorf, B.3    Scheeder, M.R.4    Wenk, C.5    Gunther, D.6
  • 61
    • 31644437054 scopus 로고    scopus 로고
    • Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes
    • M.Glei, S.Klenow, J.Sauer, U.Wegewitz, K.Richter, and B.L.Pool-Zobel, (2006). Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes. Mutat. Res-Fund. Mol. M. 594:162–171.
    • (2006) Mutat. Res-Fund. Mol. M. , vol.594 , pp. 162-171
    • Glei, M.1    Klenow, S.2    Sauer, J.3    Wegewitz, U.4    Richter, K.5    Pool-Zobel, B.L.6
  • 62
    • 0037373520 scopus 로고    scopus 로고
    • Food mutagens
    • R.Goldman, and P.G.Shields, (2003). Food mutagens. J. Nutr. 133:965S–973S.
    • (2003) J. Nutr. , vol.133 , pp. 965S-973S
    • Goldman, R.1    Shields, P.G.2
  • 63
    • 33847336066 scopus 로고    scopus 로고
    • Potassium diazoacetate-induced p53 mutations in vitro in relation to formation of O6-carboxymethyl- and O6-methyl-2′-deoxyguanosine DNA adducts: Relevance for gastrointestinal cancer
    • E.Gottschalg, G.B.Scott, P.A.Burns, and D.E.G.Shuker, (2006). Potassium diazoacetate-induced p53 mutations in vitro in relation to formation of O6-carboxymethyl- and O6-methyl-2′-deoxyguanosine DNA adducts:Relevance for gastrointestinal cancer. Carcinogenesis 28:356–362.
    • (2006) Carcinogenesis , vol.28 , pp. 356-362
    • Gottschalg, E.1    Scott, G.B.2    Burns, P.A.3    Shuker, D.E.G.4
  • 64
    • 84987311649 scopus 로고
    • Distribution of sodium nitrite in adipose tissue during curing
    • R.Goutefongea, R.G.Cassens, and G.Woolford, (1977). Distribution of sodium nitrite in adipose tissue during curing. J. Food Sci. 42:1637–1641.
    • (1977) J. Food Sci. , vol.42 , pp. 1637-1641
    • Goutefongea, R.1    Cassens, R.G.2    Woolford, G.3
  • 65
    • 84865980067 scopus 로고    scopus 로고
    • Recent perspectives on the relations between faecal mutagenicity, genotoxicity and diet
    • S.Gratz, R.J.Wallace, and H.El-Nezami, (2011). Recent perspectives on the relations between faecal mutagenicity, genotoxicity and diet. FPHAR 2:1–9.
    • (2011) FPHAR , vol.2 , pp. 1-9
    • Gratz, S.1    Wallace, R.J.2    El-Nezami, H.3
  • 67
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • S.I.Grivennikov, F.R.Greten, and M.Karin, (2010). Immunity, inflammation, and cancer. Cell 140:883–899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 68
    • 16244370410 scopus 로고    scopus 로고
    • Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study
    • M.J.Gunter, N.M.Probst-Hensch, V.K.Cortessis, M.Kulldorff, R.W.Haile, and R.Sinha, (2005). Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study. Carcinogenesis 26:637–642.
    • (2005) Carcinogenesis , vol.26 , pp. 637-642
    • Gunter, M.J.1    Probst-Hensch, N.M.2    Cortessis, V.K.3    Kulldorff, M.4    Haile, R.W.5    Sinha, R.6
  • 69
    • 0021759809 scopus 로고
    • Free radicals, lipid peroxidation, and cell damage
    • B.Halliwell, and J.M.Gutteridge, (1984a). Free radicals, lipid peroxidation, and cell damage. Lancet 2:1095.
    • (1984) Lancet , vol.2 , pp. 1095
    • Halliwell, B.1    Gutteridge, J.M.2
  • 70
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals, transition metals and disease
    • B.Halliwell, and J.M.Gutteridge, (1984b). Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem. J. 219:1–14.
    • (1984) Biochem. J. , vol.219 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.2
  • 71
    • 0035543070 scopus 로고    scopus 로고
    • Determination of total N-nitroso compounds and their precursors in Frankfurters, fresh Meat, dried salted fish, sauces, tobacco, and tobacco smoke particulates
    • J.Haorah, L.Zhou, X.Wang, G.Xu, and S.S.Mirvish, (2001). Determination of total N-nitroso compounds and their precursors in Frankfurters, fresh Meat, dried salted fish, sauces, tobacco, and tobacco smoke particulates. J. Agric. Food Chem. 49:6068–6078.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 6068-6078
    • Haorah, J.1    Zhou, L.2    Wang, X.3    Xu, G.4    Mirvish, S.S.5
  • 73
    • 80053905766 scopus 로고    scopus 로고
    • Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells
    • D.G.A.J.Hebels, K.J.J.Brauers, M.H.M.van Herwijnen, P.A.Georgiadis, S.A.Kyrtopoulos, J.C.S.Kleinjans, and T.M.C.M.de Kok, (2011). Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells. Toxicol. Lett. 207:232–241.
    • (2011) Toxicol. Lett. , vol.207 , pp. 232-241
    • Hebels, D.G.A.J.1    Brauers, K.J.J.2    van Herwijnen, M.H.M.3    Georgiadis, P.A.4    Kyrtopoulos, S.A.5    Kleinjans, J.C.S.6    de Kok, T.M.C.M.7
  • 74
    • 57749083520 scopus 로고    scopus 로고
    • Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression
    • M.Hedlund, V.Padler-Karavani, N.M.Varki, and A.Varki, (2008). Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression. P. Natl. Aca. Sci. USA 105:18936–18941.
    • (2008) P. Natl. Aca. Sci. USA , vol.105 , pp. 18936-18941
    • Hedlund, M.1    Padler-Karavani, V.2    Varki, N.M.3    Varki, A.4
  • 76
    • 34548137666 scopus 로고    scopus 로고
    • Red meat and colon cancer: Heme proteins and nitrite in the gut. A commentary on ‘Diet-induced endogenous formation of nitroso compounds in the GI tract’
    • N.Hogg, (2007). Red meat and colon cancer:Heme proteins and nitrite in the gut. A commentary on ‘Diet-induced endogenous formation of nitroso compounds in the GI tract’. Free Radic. Biol. Med. 43:1037–1039.
    • (2007) Free Radic. Biol. Med. , vol.43 , pp. 1037-1039
    • Hogg, N.1
  • 77
    • 36248980366 scopus 로고    scopus 로고
    • The use and control of nitrate and nitrite for the processing of meat products
    • K.O.Honikel, (2008). The use and control of nitrate and nitrite for the processing of meat products. Meat Sci. 78:68–76.
    • (2008) Meat Sci , vol.78 , pp. 68-76
    • Honikel, K.O.1
  • 82
    • 84865050645 scopus 로고    scopus 로고
    • Dietary heme-mediated PPARa activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon
    • N.IJssennagger, N.de Wit, M.Müller, and R.Van der Meer, (2012a). Dietary heme-mediated PPARa activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon. PLoS ONE 7:e43260.
    • (2012) PLoS ONE , vol.7 , pp. e43260
    • IJssennagger, N.1    de Wit, N.2    Müller, M.3    Van der Meer, R.4
  • 84
    • 3042599473 scopus 로고    scopus 로고
    • Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: The role of inflammation
    • S.H.Itzkowitz, and X.Yio, (2004). Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease:The role of inflammation. Am. J. Physiol. Gastr. L. 287:G7–G17.
    • (2004) Am. J. Physiol. Gastr. L. , vol.287 , pp. G7-G17
    • Itzkowitz, S.H.1    Yio, X.2
  • 85
    • 3843129544 scopus 로고    scopus 로고
    • Development of a food database of nitrosamines, heterocyclic amines, and polycyclic aromatic hydrocarbons
    • P.Jakszyn, A.Agudo, R.Ibanez, R.Garcia-Closas, G.Pera, P.Amiano, and C.A.Gonzalez, (2004). Development of a food database of nitrosamines, heterocyclic amines, and polycyclic aromatic hydrocarbons. J. Nutr. 134:2011–2014.
    • (2004) J. Nutr. , vol.134 , pp. 2011-2014
    • Jakszyn, P.1    Agudo, A.2    Ibanez, R.3    Garcia-Closas, R.4    Pera, G.5    Amiano, P.6    Gonzalez, C.A.7
  • 86
    • 84874585293 scopus 로고    scopus 로고
    • Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis
    • E.L.Jamin, A.Riu, T.Douki, L.Debrauwer, J.P.Cravedi, D.Zalko, and M.Audebert, (2013). Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis. PLoS ONE 8:e58591.
    • (2013) PLoS ONE , vol.8 , pp. e58591
    • Jamin, E.L.1    Riu, A.2    Douki, T.3    Debrauwer, L.4    Cravedi, J.P.5    Zalko, D.6    Audebert, M.7
  • 90
    • 77951956548 scopus 로고    scopus 로고
    • Effect of dietary meat and fish on endogenous nitrosation, inflammation and genotoxicity of faecal water
    • A.M.C.P.Joosen, E.Lecommandeur, G.G.C.Kuhnle, S.M.Aspinall, L.Kap, and S.A.Rodwell, (2010). Effect of dietary meat and fish on endogenous nitrosation, inflammation and genotoxicity of faecal water. Mutagenesis 25:243–247.
    • (2010) Mutagenesis , vol.25 , pp. 243-247
    • Joosen, A.M.C.P.1    Lecommandeur, E.2    Kuhnle, G.G.C.3    Aspinall, S.M.4    Kap, L.5    Rodwell, S.A.6
  • 91
    • 19444383488 scopus 로고    scopus 로고
    • Genotoxicity of heat-processed foods
    • M.Jägerstad, and K.Skog, (2005). Genotoxicity of heat-processed foods. Mutat. Res.-Fund. Mol. M. 574:156–172.
    • (2005) Mutat. Res.-Fund. Mol. M. , vol.574 , pp. 156-172
    • Jägerstad, M.1    Skog, K.2
  • 92
    • 34347341773 scopus 로고    scopus 로고
    • A cohort study of dietary iron and heme iron intake and risk of colorectal cancer in women
    • G.C.Kabat, A.B.Miller, M.Jain, and T.E.Rohan, (2007). A cohort study of dietary iron and heme iron intake and risk of colorectal cancer in women. Br. J. Cancer 97:118–122.
    • (2007) Br. J. Cancer , vol.97 , pp. 118-122
    • Kabat, G.C.1    Miller, A.B.2    Jain, M.3    Rohan, T.E.4
  • 93
    • 0035866802 scopus 로고    scopus 로고
    • Intestinal microflora are cecessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice
    • S.Kado, K.Uchida, H.Funabashi, S.Iwata, Y.Nagata, M.Ando, M.Onoue, Y.Matsuoka, M.Ohwaki, and M.Morotomi, (2001). Intestinal microflora are cecessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice. Cancer Res. 61:2395–2398.
    • (2001) Cancer Res , vol.61 , pp. 2395-2398
    • Kado, S.1    Uchida, K.2    Funabashi, H.3    Iwata, S.4    Nagata, Y.5    Ando, M.6    Onoue, M.7    Matsuoka, Y.8    Ohwaki, M.9    Morotomi, M.10
  • 94
    • 0031712320 scopus 로고    scopus 로고
    • Dietary hydroperoxides of linoleic acid decompose to aldehydes in stomach before being absorbed into the body
    • K.Kanazawa, and H.Ashida, (1998). Dietary hydroperoxides of linoleic acid decompose to aldehydes in stomach before being absorbed into the body. BBA Lipid. Lipid Met. 1393:349–361.
    • (1998) BBA Lipid. Lipid Met. , vol.1393 , pp. 349-361
    • Kanazawa, K.1    Ashida, H.2
  • 95
    • 34948892098 scopus 로고    scopus 로고
    • Dietary advanced lipid oxidation endproducts are risk factors to human health
    • J.Kanner, (2007). Dietary advanced lipid oxidation endproducts are risk factors to human health. Mol. Nutr. Food Res. 51:1094–1101.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1094-1101
    • Kanner, J.1
  • 97
    • 84866392769 scopus 로고    scopus 로고
    • Protection by polyphenols of postprandial human plasma and low-density lipoprotein modification: The stomach as a bioreactor
    • J.Kanner, S.Gorelik, S.Roman, and R.Kohen, (2012). Protection by polyphenols of postprandial human plasma and low-density lipoprotein modification:The stomach as a bioreactor. J. Agric. Food Chem. 60:8790–8796.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 8790-8796
    • Kanner, J.1    Gorelik, S.2    Roman, S.3    Kohen, R.4
  • 98
    • 1242328732 scopus 로고    scopus 로고
    • Effect of intestinal microfloras from vegetarians and meat eaters on the genotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline, a carcinogenic heterocyclic amine
    • F.Kassie, E.F.Lhoste, A.Bruneau, M.Zsivkovits, F.Ferk, M.Uhl, T.Zidek, and S.Knasmüller, (2004). Effect of intestinal microfloras from vegetarians and meat eaters on the genotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline, a carcinogenic heterocyclic amine. J. Chromatogr. B 802:211–215.
    • (2004) J. Chromatogr. B , vol.802 , pp. 211-215
    • Kassie, F.1    Lhoste, E.F.2    Bruneau, A.3    Zsivkovits, M.4    Ferk, F.5    Uhl, M.6    Zidek, T.7    Knasmüller, S.8
  • 99
    • 0035054201 scopus 로고    scopus 로고
    • Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study
    • N.Kazerouni, R.Sinha, C.H.Hsu, A.Greenberg, and N.Rothman, (2001). Analysis of 200 food items for benzo[a]pyrene and estimation of its intake in an epidemiologic study. Food Chem. Toxicol. 39:423–436.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 423-436
    • Kazerouni, N.1    Sinha, R.2    Hsu, C.H.3    Greenberg, A.4    Rothman, N.5
  • 100
    • 0345369741 scopus 로고    scopus 로고
    • Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: A follow-up study
    • P.Knekt, R.Järvinen, J.Dich, and T.Hakulinen, (1999). Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds:A follow-up study. Int. J. Cancer 80:852–856.
    • (1999) Int. J. Cancer , vol.80 , pp. 852-856
    • Knekt, P.1    Järvinen, R.2    Dich, J.3    Hakulinen, T.4
  • 102
    • 68849127181 scopus 로고    scopus 로고
    • Inflammation and colorectal cancer
    • S.Kraus, and N.Arber, (2009). Inflammation and colorectal cancer. Curr. Opin. Pharmacol. 9:405–410.
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 405-410
    • Kraus, S.1    Arber, N.2
  • 103
    • 36749088470 scopus 로고    scopus 로고
    • Dietary meat, endogenous nitrosation and colorectal cancer
    • G.G.C.Kuhnle, and S.A.Bingham, (2007). Dietary meat, endogenous nitrosation and colorectal cancer. Biochem. Soc. Trans. 35:1355–1357.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1355-1357
    • Kuhnle, G.G.C.1    Bingham, S.A.2
  • 105
    • 12144255051 scopus 로고    scopus 로고
    • Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: The Swedish Mammography Cohort
    • S.C.Larsson, J.Rafter, L.Holmberg, L.Bergkvist, and A.Wolk, (2005). Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum:The Swedish Mammography Cohort. Int. J. Cancer 113:829–834.
    • (2005) Int. J. Cancer , vol.113 , pp. 829-834
    • Larsson, S.C.1    Rafter, J.2    Holmberg, L.3    Bergkvist, L.4    Wolk, A.5
  • 106
    • 0023639586 scopus 로고
    • Bacterially catalysed N-nitrosation reactions and their relative importance in the human stomach
    • S.A.Leach, M.Thompson, and M.Hill, (1987). Bacterially catalysed N-nitrosation reactions and their relative importance in the human stomach. Carcinogenesis 8:1907–1912.
    • (1987) Carcinogenesis , vol.8 , pp. 1907-1912
    • Leach, S.A.1    Thompson, M.2    Hill, M.3
  • 107
    • 1542318322 scopus 로고    scopus 로고
    • Heme iron, zinc, alcohol consumption, and colon cancer: Iowa Women's Health Study
    • D.H.Lee, K.E.Anderson, L.J.Harnack, A.R.Folsom, and D.R.Jacobs, (2004). Heme iron, zinc, alcohol consumption, and colon cancer:Iowa Women's Health Study. J. Natl. Cancer I. 96:403–407.
    • (2004) J. Natl. Cancer I. , vol.96 , pp. 403-407
    • Lee, D.H.1    Anderson, K.E.2    Harnack, L.J.3    Folsom, A.R.4    Jacobs, D.R.5
  • 110
    • 32944468704 scopus 로고    scopus 로고
    • Red meat enhances the colonic formation of the DNA adduct O6-Carboxymethyl Guanine: Implications for colorectal cancer risk
    • M.H.Lewin, N.Bailey, T.Bandaletova, R.Bowman, A.J.Cross, J.Pollock, D.E.G.Shuker, and S.A.Bingham, (2006). Red meat enhances the colonic formation of the DNA adduct O6-Carboxymethyl Guanine:Implications for colorectal cancer risk. Cancer Res. 66:1859–1865.
    • (2006) Cancer Res , vol.66 , pp. 1859-1865
    • Lewin, M.H.1    Bailey, N.2    Bandaletova, T.3    Bowman, R.4    Cross, A.J.5    Pollock, J.6    Shuker, D.E.G.7    Bingham, S.A.8
  • 111
    • 0020016636 scopus 로고
    • DNA repair enzymes
    • T.Lindahl, (1982). DNA repair enzymes. Annu. Rev. Biochem. 51:61–87.
    • (1982) Annu. Rev. Biochem. , vol.51 , pp. 61-87
    • Lindahl, T.1
  • 112
    • 79956008518 scopus 로고    scopus 로고
    • Is dietary fat associated with the risk of colorectal cancer? A meta-analysis of 13 prospective cohort studies
    • L.Liu, W.Zhuang, R.Q.Wang, R.Mukherjee, S.M.Xiao, Z.Chen, X.T.Wu, Y.Zhou, and H.Y.Zhang, (2011). Is dietary fat associated with the risk of colorectal cancer? A meta-analysis of 13 prospective cohort studies. Eur. J. Nutr. 50:173–184.
    • (2011) Eur. J. Nutr. , vol.50 , pp. 173-184
    • Liu, L.1    Zhuang, W.2    Wang, R.Q.3    Mukherjee, R.4    Xiao, S.M.5    Chen, Z.6    Wu, X.T.7    Zhou, Y.8    Zhang, H.Y.9
  • 113
    • 79955462765 scopus 로고    scopus 로고
    • N-nitroso compounds and cancer incidence: The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study
    • Y.H.Loh, P.Jakszyn, R.N.Luben, A.A.Mulligan, P.N.Mitrou, and K.T.Khaw, (2011). N-nitroso compounds and cancer incidence:The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study. Am. J. Clin. Nutr. 93:1053–1061.
    • (2011) Am. J. Clin. Nutr. , vol.93 , pp. 1053-1061
    • Loh, Y.H.1    Jakszyn, P.2    Luben, R.N.3    Mulligan, A.A.4    Mitrou, P.N.5    Khaw, K.T.6
  • 115
    • 84859970531 scopus 로고    scopus 로고
    • Trace mineral status and toxic metal accumulation in extensive and intensive pigs in NW Spain
    • M.Lopez-Alonso, M.Garcia-Vaquero, J.L.Benedito, C.Castillo, and M.Miranda, (2012). Trace mineral status and toxic metal accumulation in extensive and intensive pigs in NW Spain. Livestock Sci. 146:47–53.
    • (2012) Livestock Sci. , vol.146 , pp. 47-53
    • Lopez-Alonso, M.1    Garcia-Vaquero, M.2    Benedito, J.L.3    Castillo, C.4    Miranda, M.5
  • 117
    • 75249097116 scopus 로고    scopus 로고
    • Chemical modeling of heme-induced lipid oxidation in gastric conditions and inhibition by dietary polyphenols
    • B.Lorrain, O.Dangles, C.Genot, and C.Dufour, (2009). Chemical modeling of heme-induced lipid oxidation in gastric conditions and inhibition by dietary polyphenols. J. Agric. Food Chem. 58:676–683.
    • (2009) J. Agric. Food Chem. , vol.58 , pp. 676-683
    • Lorrain, B.1    Dangles, O.2    Genot, C.3    Dufour, C.4
  • 118
    • 79956033905 scopus 로고    scopus 로고
    • Recent advances in understanding the role of diet and obesity in the development of colorectal cancer
    • E.K.Lund, N.J.Belshaw, G.O.Elliott, and I.T.Johnson, (2011). Recent advances in understanding the role of diet and obesity in the development of colorectal cancer. P. Nutr. Soc. 70:194–204.
    • (2011) P. Nutr. Soc. , vol.70 , pp. 194-204
    • Lund, E.K.1    Belshaw, N.J.2    Elliott, G.O.3    Johnson, I.T.4
  • 120
    • 0026447831 scopus 로고
    • Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef
    • A.M.Lynch, M.G.Knize, A.R.Boobis, N.J.Gooderham, D.S.Davies, and S.Murray, (1992). Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef. Cancer Res. 52:6216–6223.
    • (1992) Cancer Res. , vol.52 , pp. 6216-6223
    • Lynch, A.M.1    Knize, M.G.2    Boobis, A.R.3    Gooderham, N.J.4    Davies, D.S.5    Murray, S.6
  • 121
    • 82555191404 scopus 로고    scopus 로고
    • Dietary patterns and colorectal cancer: Systematic review and meta-analysis
    • B.Magalhaes, B.Peleteiro, and N.Lunet, (2012). Dietary patterns and colorectal cancer:Systematic review and meta-analysis. Eur. J. Cancer Prev. 21:15–23.
    • (2012) Eur. J. Cancer Prev. , vol.21 , pp. 15-23
    • Magalhaes, B.1    Peleteiro, B.2    Lunet, N.3
  • 123
    • 72449176846 scopus 로고    scopus 로고
    • Molecular origins of cancer: Molecular basis of colorectal cancer
    • S.D.Markowitz, and M.M.Bertagnolli, (2009). Molecular origins of cancer:Molecular basis of colorectal cancer. N. Engl. J. Med. 361:2449–2460.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 124
    • 0028690470 scopus 로고
    • DNA adducts of alpha,beta-unsaturated aldehydes and dicarbonyl compounds
    • L.J.Marnett, (1994). DNA adducts of alpha,beta-unsaturated aldehydes and dicarbonyl compounds. IARC Sci. Publ. 151–163.
    • (1994) IARC Sci. Publ. , pp. 151-163
    • Marnett, L.J.1
  • 125
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • L.J.Marnett, (2000). Oxyradicals and DNA damage. Carcinogenesis 21:361–370.
    • (2000) Carcinogenesis , vol.21 , pp. 361-370
    • Marnett, L.J.1
  • 126
    • 84862546573 scopus 로고    scopus 로고
    • Inflammation and cancer: Chemical approaches to mechanisms, imaging, and treatment
    • L.J.Marnett, (2012). Inflammation and cancer:Chemical approaches to mechanisms, imaging, and treatment. J. Org. Chem. 77:5224–5238.
    • (2012) J. Org. Chem. , vol.77 , pp. 5224-5238
    • Marnett, L.J.1
  • 127
    • 0023731012 scopus 로고
    • An investigation of the endogenous formation of apparent total n-nitroso compounds in conventional microflora and germ-free rats
    • Massey, R. C., Key, P. E., Mallett, A. K., and Rowland, I. R. (1988). An investigation of the endogenous formation of apparent total n-nitroso compounds in conventional microflora and germ-free rats. Food Chem. Toxicol. 26(7):595–600.
    • (1988) Food Chem. Toxicol , vol.26 , pp. 595-600
  • 129
    • 0027083905 scopus 로고
    • Ambient concentrations and exposure to carcinogenic PAHs in the environment
    • C.A.Menzie, B.B.Potocki, and J.Santodonato, (1992). Ambient concentrations and exposure to carcinogenic PAHs in the environment. Environ. Sci. Technol. 26:1278–1284.
    • (1992) Environ. Sci. Technol. , vol.26 , pp. 1278-1284
    • Menzie, C.A.1    Potocki, B.B.2    Santodonato, J.3
  • 131
    • 0029071838 scopus 로고
    • Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC
    • S.S.Mirvish, (1995). Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC. Cancer Lett. 93:17–48.
    • (1995) Cancer Lett , vol.93 , pp. 17-48
    • Mirvish, S.S.1
  • 132
    • 58149098746 scopus 로고    scopus 로고
    • Effect of feeding nitrite, ascorbate, hemin, and omeprazole on excretion of fecal total apparent N-nitroso compounds in mice
    • S.S.Mirvish, M.E.Davis, M.P.Lisowyj, and N.W.Gaikwad, (2008). Effect of feeding nitrite, ascorbate, hemin, and omeprazole on excretion of fecal total apparent N-nitroso compounds in mice. Chem. Res. Toxicol. 21:2344–2351.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 2344-2351
    • Mirvish, S.S.1    Davis, M.E.2    Lisowyj, M.P.3    Gaikwad, N.W.4
  • 133
    • 0037358850 scopus 로고    scopus 로고
    • N-Nitroso compounds in the gastrointestinal tract of rats and in the feces of mice with induced colitis or fed hot dogs or beef
    • S.S.Mirvish, J.Haorah, L.Zhou, M.Hartman, C.R.Morris, and M.L.Clapper, (2003). N-Nitroso compounds in the gastrointestinal tract of rats and in the feces of mice with induced colitis or fed hot dogs or beef. Carcinogenesis 24:595–603.
    • (2003) Carcinogenesis , vol.24 , pp. 595-603
    • Mirvish, S.S.1    Haorah, J.2    Zhou, L.3    Hartman, M.4    Morris, C.R.5    Clapper, M.L.6
  • 134
    • 0015496831 scopus 로고
    • Ascorbate-nitrite reaction: Possible means of blocking the formation of carcinogenic N-nitroso compounds
    • S.S.Mirvish, L.Wallcave, M.Eagen, and P.Shubik, (1972). Ascorbate-nitrite reaction:Possible means of blocking the formation of carcinogenic N-nitroso compounds. Science 177:65–68.
    • (1972) Science , vol.177 , pp. 65-68
    • Mirvish, S.S.1    Wallcave, L.2    Eagen, M.3    Shubik, P.4
  • 135
    • 0017726405 scopus 로고
    • Role of diet in cancer etiology
    • B.Modan, (1977). Role of diet in cancer etiology. Cancer 40:1887–1891.
    • (1977) Cancer , vol.40 , pp. 1887-1891
    • Modan, B.1
  • 136
    • 77957162470 scopus 로고    scopus 로고
    • Colorectal cancer: What should patients and families be told to lower the risk of colorectal cancer?
    • H.G.Moore, (2010). Colorectal cancer:What should patients and families be told to lower the risk of colorectal cancer? Surgical Oncol. 19:693–710.
    • (2010) Surgical Oncol , vol.19 , pp. 693-710
    • Moore, H.G.1
  • 137
    • 84877826018 scopus 로고    scopus 로고
    • Toll-like receptor signalling and their therapeutic targeting in colorectal cancer
    • S.Moossavi, and N.Rezaei, (2013). Toll-like receptor signalling and their therapeutic targeting in colorectal cancer. Int. Immunopharmacol. 16:199–209.
    • (2013) Int. Immunopharmacol. , vol.16 , pp. 199-209
    • Moossavi, S.1    Rezaei, N.2
  • 138
    • 0000852615 scopus 로고
    • The antioxidant activities of nitrite and nitrosylmyoglobin in cooked meats
    • P.A.Morrissey, and J.Z.Tichivangana, (1985). The antioxidant activities of nitrite and nitrosylmyoglobin in cooked meats. Meat Sci. 14:175–190.
    • (1985) Meat Sci , vol.14 , pp. 175-190
    • Morrissey, P.A.1    Tichivangana, J.Z.2
  • 139
    • 0344217243 scopus 로고
    • Mass-spectrometric study of derivatives formed by the reaction of oleic-acid with nitrite - some evidence for the formation of derivatives nitrosubstituted on the alpha-position of the double-bond
    • M.Mouloud, F.Metro, R.Goutefongea, and J.P.Dumont, (1992). Mass-spectrometric study of derivatives formed by the reaction of oleic-acid with nitrite - some evidence for the formation of derivatives nitrosubstituted on the alpha-position of the double-bond. Sci. Aliment. 12:371–382.
    • (1992) Sci. Aliment. , vol.12 , pp. 371-382
    • Mouloud, M.1    Metro, F.2    Goutefongea, R.3    Dumont, J.P.4
  • 140
    • 84858116393 scopus 로고    scopus 로고
    • Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis
    • M.Murata, R.Thanan, N.Ma, and S.Kawanishi, (2012). Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis. J. Biomed. Biotechnol. 2012:623019.
    • (2012) J. Biomed. Biotechnol. , vol.2012 , pp. 623019
    • Murata, M.1    Thanan, R.2    Ma, N.3    Kawanishi, S.4
  • 141
  • 142
    • 84983046492 scopus 로고    scopus 로고
    • Available from
    • NUBEL. (2013). De Belgische Voedingsmiddelentabel. Available from http://www.nubel.com/nl/voedingsmiddelentabel.asp. Accessed December 1, 2013.
    • (2013) De Belgische Voedingsmiddelentabel
  • 143
    • 0028218474 scopus 로고
    • Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
    • H.Ohshima, and H.Bartsch, (1994). Chronic infections and inflammatory processes as cancer risk factors:Possible role of nitric oxide in carcinogenesis. Mutat. Res. 305:253–264.
    • (1994) Mutat. Res. , vol.305 , pp. 253-264
    • Ohshima, H.1    Bartsch, H.2
  • 144
    • 0030631749 scopus 로고    scopus 로고
    • Faecal steroids and colorectal carcinogenesis
    • R.W.Owen, (1997). Faecal steroids and colorectal carcinogenesis. Scand. J. Gastroenterol. Suppl. 222:76–82.
    • (1997) Scand. J. Gastroenterol. Suppl. , vol.222 , pp. 76-82
    • Owen, R.W.1
  • 146
    • 61449131610 scopus 로고    scopus 로고
    • Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health Study
    • Y.Park, M.F.Leitzmann, A.F.Subar, A.Hollenbeck, and A.Schatzkin, (2009). Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health Study. Arch. Int. Med. 169:391–401.
    • (2009) Arch. Int. Med. , vol.169 , pp. 391-401
    • Park, Y.1    Leitzmann, M.F.2    Subar, A.F.3    Hollenbeck, A.4    Schatzkin, A.5
  • 147
    • 0034448148 scopus 로고    scopus 로고
    • Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats
    • G.Parnaud, B.Pignatelli, G.Peiffer, S.Taché, and D.E.Corpet, (2000). Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats. Nutr. Cancer 38:74–80.
    • (2000) Nutr. Cancer , vol.38 , pp. 74-80
    • Parnaud, G.1    Pignatelli, B.2    Peiffer, G.3    Taché, S.4    Corpet, D.E.5
  • 148
    • 84863105839 scopus 로고    scopus 로고
    • Sodium nitrite: The “cure” for nitric oxide insufficiency
    • D.K.Parthasarathy, and N.S.Bryan, (2012). Sodium nitrite:The “cure” for nitric oxide insufficiency. Meat Sci. 92:274–279.
    • (2012) Meat Sci , vol.92 , pp. 274-279
    • Parthasarathy, D.K.1    Bryan, N.S.2
  • 150
    • 0020523616 scopus 로고
    • Fifty years of benzo(a)pyrene
    • D.H.Phillips, (1983). Fifty years of benzo(a)pyrene. Nature 303:468–472.
    • (1983) Nature , vol.303 , pp. 468-472
    • Phillips, D.H.1
  • 151
    • 0033565866 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons in the diet
    • D.H.Phillips, (1999). Polycyclic aromatic hydrocarbons in the diet. Mutat. Res.-Gen. Tox. En. 443:139–147.
    • (1999) Mutat. Res.-Gen. Tox. En. , vol.443 , pp. 139-147
    • Phillips, D.H.1
  • 152
    • 0028285404 scopus 로고
    • Polycyclic hydrocarbon activation: Bay regions and beyond
    • D.H.Phillips, and P.L.Grover, (1994). Polycyclic hydrocarbon activation:Bay regions and beyond. Drug. Metab. Rev. 26:443–467.
    • (1994) Drug. Metab. Rev. , vol.26 , pp. 443-467
    • Phillips, D.H.1    Grover, P.L.2
  • 153
    • 0029854460 scopus 로고    scopus 로고
    • Metabolism of exogenous and endogenous arachidonic acid in cancer
    • S.D.Phinney, (1996). Metabolism of exogenous and endogenous arachidonic acid in cancer. Adv. Exp. Med. Biol. 399:87–94.
    • (1996) Adv. Exp. Med. Biol. , vol.399 , pp. 87-94
    • Phinney, S.D.1
  • 156
    • 4744342495 scopus 로고    scopus 로고
    • Beef meat and blood sausage promote the formation of azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colons
    • F.H.F.Pierre, A.Reeman, S.Taché, R.Van der Meer, and D.E.Corpet, (2004). Beef meat and blood sausage promote the formation of azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colons. J. Nutr. 134:2711–2716.
    • (2004) J. Nutr. , vol.134 , pp. 2711-2716
    • Pierre, F.H.F.1    Reeman, A.2    Taché, S.3    Van der Meer, R.4    Corpet, D.E.5
  • 157
    • 77954024754 scopus 로고    scopus 로고
    • Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon
    • F.H.F.Pierre, R.L.Santarelli, O.Allam, S.Taché, N.Naud, F.Guéraud, and D.E.Corpet, (2010). Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon. Nutr. Cancer 62:567–573.
    • (2010) Nutr. Cancer , vol.62 , pp. 567-573
    • Pierre, F.H.F.1    Santarelli, R.L.2    Allam, O.3    Taché, S.4    Naud, N.5    Guéraud, F.6    Corpet, D.E.7
  • 160
    • 84983041952 scopus 로고    scopus 로고
    • Total iron and heme iron content of south african lean meat (beef, lamb, pork and chicken)
    • B.Pretorius, H.C.Schoenfeldt, and N.Hall, (2013). Total iron and heme iron content of south african lean meat (beef, lamb, pork and chicken). Ann. Nut. Metabol. 63:1651–1651.
    • (2013) Ann. Nut. Metabol. , vol.63 , pp. 1651
    • Pretorius, B.1    Schoenfeldt, H.C.2    Hall, N.3
  • 162
    • 2942672906 scopus 로고    scopus 로고
    • Cooking temperature effects on the forms of iron and levels of several other compounds in beef semitendinosus muscle
    • R.W.Purchas, S.M.Rutherfurd, P.D.Pearce, R.Vather, and B.H.P.Wilkinson, (2004). Cooking temperature effects on the forms of iron and levels of several other compounds in beef semitendinosus muscle. Meat Sci. 68:201–207.
    • (2004) Meat Sci , vol.68 , pp. 201-207
    • Purchas, R.W.1    Rutherfurd, S.M.2    Pearce, P.D.3    Vather, R.4    Wilkinson, B.H.P.5
  • 163
    • 0141652806 scopus 로고    scopus 로고
    • Variation in the form of iron in beef and lamb meat and losses of iron during cooking and storage
    • R.W.Purchas, D.C.Simcock, T.W.Knight, and B.H.P.Wilkinson, (2003). Variation in the form of iron in beef and lamb meat and losses of iron during cooking and storage. Int. J. Food Sci. Technol. 38:827–837.
    • (2003) Int. J. Food Sci. Technol. , vol.38 , pp. 827-837
    • Purchas, R.W.1    Simcock, D.C.2    Knight, T.W.3    Wilkinson, B.H.P.4
  • 164
    • 0033045404 scopus 로고    scopus 로고
    • Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: An electron paramagnetic resonance spin trapping study
    • S.Y.Qian, and G.R.Buettner, (1999). Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations:An electron paramagnetic resonance spin trapping study. Free Radic. Biol. Med. 26:1447–1456.
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 1447-1456
    • Qian, S.Y.1    Buettner, G.R.2
  • 165
    • 84857648442 scopus 로고    scopus 로고
    • Bioaccessibility of Se, Cu, Zn, Mn and Fe, and heme iron content in unaged and aged meat of Hereford and Braford steers fed pasture
    • A.Ramos, M.C.Cabrera, and A.Saadoun, (2012). Bioaccessibility of Se, Cu, Zn, Mn and Fe, and heme iron content in unaged and aged meat of Hereford and Braford steers fed pasture. Meat Sci. 91:116–124.
    • (2012) Meat Sci , vol.91 , pp. 116-124
    • Ramos, A.1    Cabrera, M.C.2    Saadoun, A.3
  • 166
    • 0026726738 scopus 로고
    • Dietary fat and colon cancer: Animal model studies
    • B.S.Reddy, (1992). Dietary fat and colon cancer:Animal model studies. Lipids 27:807–813.
    • (1992) Lipids , vol.27 , pp. 807-813
    • Reddy, B.S.1
  • 168
    • 0020460965 scopus 로고
    • Factors controlling the growth of Clostridium botulinum types A and B in pasteurized, cured meats. V. Prediction of toxin production: Non-linear effects of storage temperature and salt concentration
    • A.Robinson, A.M.Gibson, and T.A.Roberts, (1982). Factors controlling the growth of Clostridium botulinum types A and B in pasteurized, cured meats. V. Prediction of toxin production:Non-linear effects of storage temperature and salt concentration. J. Food Technol. 17:727–744.
    • (1982) J. Food Technol. , vol.17 , pp. 727-744
    • Robinson, A.1    Gibson, A.M.2    Roberts, T.A.3
  • 169
    • 65549125452 scopus 로고    scopus 로고
    • Heterocyclic aromatic amine intake increases colorectal adenoma risk: Findings from a prospective European cohort study
    • S.Rohrmann, S.Hermann, and J.Linseisen, (2009). Heterocyclic aromatic amine intake increases colorectal adenoma risk:Findings from a prospective European cohort study. Am. J. Clin. Nutr. 89:1418–1424.
    • (2009) Am. J. Clin. Nutr. , vol.89 , pp. 1418-1424
    • Rohrmann, S.1    Hermann, S.2    Linseisen, J.3
  • 172
    • 0028151118 scopus 로고
    • Influence of sex and carcinogen treatment protocol on tumor latency and frequency of K-ras mutations in N-methyl-N-nitrosourea-induced lymphomas
    • E.Romach, J.Moore, S.Rummel, and E.Richie, (1994). Influence of sex and carcinogen treatment protocol on tumor latency and frequency of K-ras mutations in N-methyl-N-nitrosourea-induced lymphomas. Carcinogenesis 15:2275–2280.
    • (1994) Carcinogenesis , vol.15 , pp. 2275-2280
    • Romach, E.1    Moore, J.2    Rummel, S.3    Richie, E.4
  • 173
    • 78650530961 scopus 로고    scopus 로고
    • The potential for increasing the concentrations of micronutrients relevant to human nutrition in meat, milk and eggs
    • J.A.Rooke, J.F.Flockhart, and N.H.Sparks, (2010). The potential for increasing the concentrations of micronutrients relevant to human nutrition in meat, milk and eggs. J. Agr. Sci. 148:603–614.
    • (2010) J. Agr. Sci. , vol.148 , pp. 603-614
    • Rooke, J.A.1    Flockhart, J.F.2    Sparks, N.H.3
  • 174
    • 45949123852 scopus 로고
    • Nitrosating agents from the reaction between methyl oleate and dinitrogen trioxide: Identification and mutagenicity
    • H.D.Ross, J.Henion, J.G.Babish, and J.H.Hotchkiss, (1987). Nitrosating agents from the reaction between methyl oleate and dinitrogen trioxide:Identification and mutagenicity. Food Chem. 23:207–222.
    • (1987) Food Chem , vol.23 , pp. 207-222
    • Ross, H.D.1    Henion, J.2    Babish, J.G.3    Hotchkiss, J.H.4
  • 175
    • 0025299609 scopus 로고
    • cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells
    • B.Rydberg, N.Spurr, and P.Karran, (1990). cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells. J. Biol. Chem. 265:9563–9569.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9563-9569
    • Rydberg, B.1    Spurr, N.2    Karran, P.3
  • 176
    • 0038580916 scopus 로고    scopus 로고
    • Meat nitrosamine contamination level depending on animal breeding factors
    • R.Rywotycki, (2003). Meat nitrosamine contamination level depending on animal breeding factors. Meat Sci. 65:669–676.
    • (2003) Meat Sci , vol.65 , pp. 669-676
    • Rywotycki, R.1
  • 177
    • 0022399410 scopus 로고
    • Mechanisms of carcinogenesis induced by alkylating agents
    • R.Saffhill, G.P.Margison, and P.J.O’Connor, (1985). Mechanisms of carcinogenesis induced by alkylating agents. BBA-Rev. Cancer 823:111–145.
    • (1985) BBA-Rev. Cancer , vol.823 , pp. 111-145
    • Saffhill, R.1    Margison, G.P.2    O’Connor, P.J.3
  • 180
    • 41449100108 scopus 로고    scopus 로고
    • Processed meat and colorectal cancer: A review of epidemiologic and experimental evidence
    • R.L.Santarelli, F.Pierre, and D.E.Corpet, (2008). Processed meat and colorectal cancer:A review of epidemiologic and experimental evidence. Nutr. Cancer 60:131–144.
    • (2008) Nutr. Cancer , vol.60 , pp. 131-144
    • Santarelli, R.L.1    Pierre, F.2    Corpet, D.E.3
  • 181
    • 77954696377 scopus 로고    scopus 로고
    • Meat processing and colon carcinogenesis: Cooked, nitrite-treated, and oxidized high-heme cured meat promotes mucin-depleted foci in rats
    • R.L.Santarelli, J.L.Vendeuvre, N.Naud, S.Taché, F.Guéraud, M.Viau, C.Genot, D.E.Corpet, and F.H.F.Pierre, (2010). Meat processing and colon carcinogenesis:Cooked, nitrite-treated, and oxidized high-heme cured meat promotes mucin-depleted foci in rats. CAPR 3:852–864.
    • (2010) CAPR , vol.3 , pp. 852-864
    • Santarelli, R.L.1    Vendeuvre, J.L.2    Naud, N.3    Taché, S.4    Guéraud, F.5    Viau, M.6    Genot, C.7    Corpet, D.E.8    Pierre, F.H.F.9
  • 183
    • 79958285394 scopus 로고    scopus 로고
    • Determining iron bio-availability with a constant heme iron value
    • H.C.Schönfeldt, and N.G.Hall, (2011). Determining iron bio-availability with a constant heme iron value. J. Food Compos. Anal. 24:738–740.
    • (2011) J. Food Compos. Anal. , vol.24 , pp. 738-740
    • Schönfeldt, H.C.1    Hall, N.G.2
  • 184
    • 0033571114 scopus 로고    scopus 로고
    • Red meat and colon cancer: The cytotoxic and hyperproliferative effects of dietary heme
    • A.L.A.Sesink, D.S.M.L.Termont, J.H.Kleibeuker, and R.Van der Meer, (1999). Red meat and colon cancer:The cytotoxic and hyperproliferative effects of dietary heme. Cancer Res. 59:5704–5709.
    • (1999) Cancer Res. , vol.59 , pp. 5704-5709
    • Sesink, A.L.A.1    Termont, D.S.M.L.2    Kleibeuker, J.H.3    Van der Meer, R.4
  • 185
    • 0034790408 scopus 로고    scopus 로고
    • Red meat and colon cancer: Dietary haem-induced colonic cytotoxicity and epithelial hyperproliferation are inhibited by calcium
    • A.L.A.Sesink, D.S.M.L.Termont, J.H.Kleibeuker, and R.Van der Meer, (2001). Red meat and colon cancer:Dietary haem-induced colonic cytotoxicity and epithelial hyperproliferation are inhibited by calcium. Carcinogenesis 22:1653–1659.
    • (2001) Carcinogenesis , vol.22 , pp. 1653-1659
    • Sesink, A.L.A.1    Termont, D.S.M.L.2    Kleibeuker, J.H.3    Van der Meer, R.4
  • 186
    • 0026515754 scopus 로고
    • Nitrite-free meat curing systems: Update and review
    • F.Shahidi, and R.B.Pegg, (1992). Nitrite-free meat curing systems:Update and review. Food Chem. 43:185–191.
    • (1992) Food Chem , vol.43 , pp. 185-191
    • Shahidi, F.1    Pegg, R.B.2
  • 187
    • 80051517632 scopus 로고    scopus 로고
    • Site-specific risk factors for colorectal cancer in a Korean population
    • A.Shin, J.Joo, J.Bak, H.R.Yang, J.Kim, S.Park, and B.H.Nam, (2011). Site-specific risk factors for colorectal cancer in a Korean population. PLoS ONE 6:e23196.
    • (2011) PLoS ONE , vol.6 , pp. e23196
    • Shin, A.1    Joo, J.2    Bak, J.3    Yang, H.R.4    Kim, J.5    Park, S.6    Nam, B.H.7
  • 188
    • 84861320026 scopus 로고    scopus 로고
    • Human safety controversies surrounding nitrate and nitrite in the diet
    • J.J.Sindelar, and A.L.Milkowski, (2012). Human safety controversies surrounding nitrate and nitrite in the diet. Nitric Oxide 26:259–266.
    • (2012) Nitric Oxide , vol.26 , pp. 259-266
    • Sindelar, J.J.1    Milkowski, A.L.2
  • 189
    • 0025831694 scopus 로고
    • Site-specific mutagenesis: Retrospective and prospective
    • B.Singer, and J.M.Essigmann, (1991). Site-specific mutagenesis:Retrospective and prospective. Carcinogenesis 12(6):949–955.
    • (1991) Carcinogenesis , vol.12 , pp. 949-955
    • Singer, B.1    Essigmann, J.M.2
  • 192
    • 79956348308 scopus 로고    scopus 로고
    • Nitric oxide and quality and safety of muscle based foods
    • L.H.Skibsted, (2011). Nitric oxide and quality and safety of muscle based foods. Nitric Oxide 24:176–183.
    • (2011) Nitric Oxide , vol.24 , pp. 176-183
    • Skibsted, L.H.1
  • 193
    • 73349135035 scopus 로고    scopus 로고
    • Trans-fatty acids and cancer: A mini-review
    • B.K.Smith, L.E.Robinson, R.Nam, and D.W.L.Ma, (2009). Trans-fatty acids and cancer:A mini-review. Br. J. Nutr. 102:1254–1266.
    • (2009) Br. J. Nutr. , vol.102 , pp. 1254-1266
    • Smith, B.K.1    Robinson, L.E.2    Nam, R.3    Ma, D.W.L.4
  • 194
    • 0036285362 scopus 로고    scopus 로고
    • Screening for heterocyclic amines in chicken cooked in various ways
    • A.Solyakov, and K.Skog, (2002). Screening for heterocyclic amines in chicken cooked in various ways. Food Chem. Toxicol. 40:1205–1211.
    • (2002) Food Chem. Toxicol. , vol.40 , pp. 1205-1211
    • Solyakov, A.1    Skog, K.2
  • 195
    • 0017046438 scopus 로고
    • Influence of dietary nitrate on nitrite content of human saliva: Possible relevance to in vivo formation of N-nitroso compounds
    • B.Spiegelhalder, G.Eisenbrand, and R.Preussmann, (1976). Influence of dietary nitrate on nitrite content of human saliva:Possible relevance to in vivo formation of N-nitroso compounds. Food Cosmet. Toxicol. 14:545–548.
    • (1976) Food Cosmet. Toxicol. , vol.14 , pp. 545-548
    • Spiegelhalder, B.1    Eisenbrand, G.2    Preussmann, R.3
  • 196
    • 0028149504 scopus 로고
    • Biological significance of trace levels of mutagenic heterocyclic aromatic amines in human diet: A critical review
    • B.Stavric, (1994). Biological significance of trace levels of mutagenic heterocyclic aromatic amines in human diet:A critical review. Food Chem. Toxicol. 32:977–994.
    • (1994) Food Chem. Toxicol. , vol.32 , pp. 977-994
    • Stavric, B.1
  • 197
    • 0033935414 scopus 로고    scopus 로고
    • Genotoxicity testing of cooked cured meat pigment (CCMP) and meat emulsion coagulates prepared with CCMP
    • M.Stevanovic, P.Cadez, B.Zlender, and M.Filipic, (2000). Genotoxicity testing of cooked cured meat pigment (CCMP) and meat emulsion coagulates prepared with CCMP. J. Food Prot. 63:945–952.
    • (2000) J. Food Prot. , vol.63 , pp. 945-952
    • Stevanovic, M.1    Cadez, P.2    Zlender, B.3    Filipic, M.4
  • 199
    • 0030981184 scopus 로고    scopus 로고
    • Overview of carcinogenic heterocyclic amines
    • T.Sugimura, (1997). Overview of carcinogenic heterocyclic amines. Mutat. Res-Fund. Mol. M. 376:211–219.
    • (1997) Mutat. Res-Fund. Mol. M. , vol.376 , pp. 211-219
    • Sugimura, T.1
  • 200
    • 61349186932 scopus 로고    scopus 로고
    • Studies on the structure and oxidation properties of extracted cooked cured meat pigment by four spectra
    • W.Q.Sun, G.H.Zhou, X.L.Xu, and Z.Q.Peng, (2009). Studies on the structure and oxidation properties of extracted cooked cured meat pigment by four spectra. Food Chem. 115:596–601.
    • (2009) Food Chem , vol.115 , pp. 596-601
    • Sun, W.Q.1    Zhou, G.H.2    Xu, X.L.3    Peng, Z.Q.4
  • 201
    • 84865541894 scopus 로고    scopus 로고
    • Profiles and concentrations of heterocyclic aromatic amines formed in beef during various heat treatments depend on the time of ripening and muscle type
    • A.Szterk, M.Roszko, K.Malek, M.Kurek, M.Zbiec, and B.Waszkiewicz-Robak, (2012). Profiles and concentrations of heterocyclic aromatic amines formed in beef during various heat treatments depend on the time of ripening and muscle type. Meat Sci. 92:587–595.
    • (2012) Meat Sci , vol.92 , pp. 587-595
    • Szterk, A.1    Roszko, M.2    Malek, K.3    Kurek, M.4    Zbiec, M.5    Waszkiewicz-Robak, B.6
  • 203
    • 0028306045 scopus 로고
    • Dose-dependent promoting effects of sodium chloride (NaCl) on rat glandular stomach carcinogenesis initiated with N-methyl-N’-nitro-N-nitrosoguanidine
    • M.Takahashi, A.Nishikawa, F.Furukawa, T.Enami, T.Hasegawa, and Y.Hayashi, (1994). Dose-dependent promoting effects of sodium chloride (NaCl) on rat glandular stomach carcinogenesis initiated with N-methyl-N’-nitro-N-nitrosoguanidine. Carcinogenesis 15:1429–1432.
    • (1994) Carcinogenesis , vol.15 , pp. 1429-1432
    • Takahashi, M.1    Nishikawa, A.2    Furukawa, F.3    Enami, T.4    Hasegawa, T.5    Hayashi, Y.6
  • 206
    • 77951997803 scopus 로고    scopus 로고
    • Effects of dietary beef and chicken with and without high amylose maize starch on blood malondialdehyde, interleukins, IGF-I, Insulin, Leptin, MMP-2, and TIMP-2 concentrations in rats
    • S.Toden, D.P.Belobrajdic, A.R.Bird, D.L.Topping, and M.A.Conlon, (2010). Effects of dietary beef and chicken with and without high amylose maize starch on blood malondialdehyde, interleukins, IGF-I, Insulin, Leptin, MMP-2, and TIMP-2 concentrations in rats. Nutr. Cancer 62:454–465.
    • (2010) Nutr. Cancer , vol.62 , pp. 454-465
    • Toden, S.1    Belobrajdic, D.P.2    Bird, A.R.3    Topping, D.L.4    Conlon, M.A.5
  • 207
    • 77955281007 scopus 로고    scopus 로고
    • Determination of mineral contents of semimembranosus muscle and liver from pure and crossbred pigs in Vojvodina (northern Serbia)
    • V.M.Tomovic, L.S.Petrovic, M.S.Tomovic, Z.S.Kevresan, and N.R.Dzinic, (2011). Determination of mineral contents of semimembranosus muscle and liver from pure and crossbred pigs in Vojvodina (northern Serbia). Food Chem. 124:342–348.
    • (2011) Food Chem , vol.124 , pp. 342-348
    • Tomovic, V.M.1    Petrovic, L.S.2    Tomovic, M.S.3    Kevresan, Z.S.4    Dzinic, N.R.5
  • 208
    • 0030783061 scopus 로고    scopus 로고
    • N-nitroso compounds and man: Sources of exposure, endogenous formation and occurrence in body fluids
    • A.R.Tricker, (1997). N-nitroso compounds and man:Sources of exposure, endogenous formation and occurrence in body fluids. Eur. J. Cancer Prev. 6:226–268.
    • (1997) Eur. J. Cancer Prev. , vol.6 , pp. 226-268
    • Tricker, A.R.1
  • 209
    • 0025801019 scopus 로고
    • Carcinogenic N-nitrosamines in the diet: Occurrence, formation, mechanisms and carcinogenic potential
    • A.R.Tricker, and R.Preussmann, (1991). Carcinogenic N-nitrosamines in the diet:Occurrence, formation, mechanisms and carcinogenic potential. Mutat. Res-Genet. Tox. 259:277–289.
    • (1991) Mutat. Res-Genet. Tox. , vol.259 , pp. 277-289
    • Tricker, A.R.1    Preussmann, R.2
  • 211
    • 84983091299 scopus 로고    scopus 로고
    • Available from
    • US Pork Center of Excellence. (2013). Pork information gathway. Available from http://www.porkgateway.org/Default.aspx. Accessed October 25, 2013.
    • (2013) Pork information gathway
  • 212
    • 33745012562 scopus 로고    scopus 로고
    • Nutrition in the prevention of gastrointestinal cancer
    • P.A.van den Brandt, and R.A.Goldbohm, (2006). Nutrition in the prevention of gastrointestinal cancer. Best Pract. Res. Cl. Ga. 20:589–603.
    • (2006) Best Pract. Res. Cl. Ga. , vol.20 , pp. 589-603
    • van den Brandt, P.A.1    Goldbohm, R.A.2
  • 213
    • 41949093540 scopus 로고    scopus 로고
    • The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3’,2’:4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells
    • L.Vanhaecke, L.Derycke, Le F.Curieux, S.Lust, D.Marzin, W.Verstraete, and M.Bracke, (2008). The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3’,2’:4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells. Toxicol. Lett. 178:61–69.
    • (2008) Toxicol. Lett. , vol.178 , pp. 61-69
    • Vanhaecke, L.1    Derycke, L.2    Curieux, F.3    Lust, S.4    Marzin, D.5    Verstraete, W.6    Bracke, M.7
  • 214
    • 4544279659 scopus 로고    scopus 로고
    • Real-time PCR of host DNA in feces to study differential exfoliation of colonocytes between rats and humans
    • E.Van Lieshout, W.Van Doesburg, and R.Van der Meer, (2004). Real-time PCR of host DNA in feces to study differential exfoliation of colonocytes between rats and humans. Scand. J. Gastroenterol. 39:852–857.
    • (2004) Scand. J. Gastroenterol. , vol.39 , pp. 852-857
    • Van Lieshout, E.1    Van Doesburg, W.2    Van der Meer, R.3
  • 215
    • 40249087075 scopus 로고    scopus 로고
    • Colorectal carcinogenesis in germ-free and conventionally reared rats: Different intestinal environments affect the systemic immunity
    • L.Vannucci, R.Stepankova, H.Kozakova, A.Fiserova, P.Rossmann, and H.Tlaskalova-Hogenova, (2008). Colorectal carcinogenesis in germ-free and conventionally reared rats:Different intestinal environments affect the systemic immunity. Int. J. Oncol. 32:609–617.
    • (2008) Int. J. Oncol. , vol.32 , pp. 609-617
    • Vannucci, L.1    Stepankova, R.2    Kozakova, H.3    Fiserova, A.4    Rossmann, P.5    Tlaskalova-Hogenova, H.6
  • 216
    • 33646802326 scopus 로고    scopus 로고
    • Quality traits in muscle biceps femoris and back-fat from purebred Iberian and reciprocal IberianxDuroc crossbred pigs
    • S.Ventanas, J.Ventanas, A.Jurado, and M.Estevez, (2006). Quality traits in muscle biceps femoris and back-fat from purebred Iberian and reciprocal IberianxDuroc crossbred pigs. Meat Sci. 73:651–659.
    • (2006) Meat Sci , vol.73 , pp. 651-659
    • Ventanas, S.1    Ventanas, J.2    Jurado, A.3    Estevez, M.4
  • 217
    • 84860221992 scopus 로고    scopus 로고
    • Effect of charcoal types and grilling conditions on formation of heterocyclic aromatic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) in grilled muscle foods
    • O.Viegas, P.Novo, E.Pinto, O.Pinho, and I.M.P.L.Ferreira, (2012). Effect of charcoal types and grilling conditions on formation of heterocyclic aromatic amines (HAs) and polycyclic aromatic hydrocarbons (PAHs) in grilled muscle foods. Food Chem. Toxicol. 50:2128–2134.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 2128-2134
    • Viegas, O.1    Novo, P.2    Pinto, E.3    Pinho, O.4    Ferreira, I.M.P.L.5
  • 218
    • 84872821702 scopus 로고    scopus 로고
    • Cancer and non-cancer health effects from food contaminant exposures for children and adults in California: A risk assessment
    • R.Vogt, D.Bennett, D.Cassady, J.Frost, B.Ritz, and I.Hertz-Picciotto, (2012). Cancer and non-cancer health effects from food contaminant exposures for children and adults in California:A risk assessment. Environ. Health 11:83.
    • (2012) Environ. Health , vol.11 , pp. 83
    • Vogt, R.1    Bennett, D.2    Cassady, D.3    Frost, J.4    Ritz, B.5    Hertz-Picciotto, I.6
  • 219
    • 79960119923 scopus 로고    scopus 로고
    • Colon cancer: A civilization disorder
    • A.J.Watson, and P.D.Collins, (2011). Colon cancer:A civilization disorder. Dig. Dis. 29:222–228.
    • (2011) Dig. Dis. , vol.29 , pp. 222-228
    • Watson, A.J.1    Collins, P.D.2
  • 221
    • 77952668256 scopus 로고    scopus 로고
    • Mechanisms of intestinal inflammation and development of associated cancers: Lessons learned from mouse models
    • A.M.Westbrook, A.Szakmary, and R.H.Schiestl, (2010). Mechanisms of intestinal inflammation and development of associated cancers:Lessons learned from mouse models. Mutat. Res.-Rev. Mutat. 705:40–59.
    • (2010) Mutat. Res.-Rev. Mutat. , vol.705 , pp. 40-59
    • Westbrook, A.M.1    Szakmary, A.2    Schiestl, R.H.3
  • 223
    • 84855310228 scopus 로고    scopus 로고
    • Relevance of protein fermentation to gut health
    • K.Windey, De V.Preter, and K.Verbeke, (2012). Relevance of protein fermentation to gut health. Mol. Nutr. Food Res. 56:184–196.
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 184-196
    • Windey, K.1    Preter, V.2    Verbeke, K.3
  • 224
    • 0011398258 scopus 로고
    • The fate of sodium nitrite in bacon
    • G.Woolford, and R.G.Cassens, (1977). The fate of sodium nitrite in bacon. J. Food Sci. 42:586–589.
    • (1977) J. Food Sci. , vol.42 , pp. 586-589
    • Woolford, G.1    Cassens, R.G.2
  • 225
    • 33746562433 scopus 로고    scopus 로고
    • The occurrence of volatile N-nitrosamines in Estonian meat products
    • S.Yurchenko, and U.Mölder, (2007). The occurrence of volatile N-nitrosamines in Estonian meat products. Food Chem. 100:1713–1721.
    • (2007) Food Chem , vol.100 , pp. 1713-1721
    • Yurchenko, S.1    Mölder, U.2
  • 226
  • 227
    • 0025862218 scopus 로고
    • Quantitative review of studies of dietary fat and rat colon carcinoma
    • L.P.Zhao, L.H.Kushi, R.D.Klein, and R.L.Prentice, (1991). Quantitative review of studies of dietary fat and rat colon carcinoma. Nutr. Cancer 15:169–177.
    • (1991) Nutr. Cancer , vol.15 , pp. 169-177
    • Zhao, L.P.1    Kushi, L.H.2    Klein, R.D.3    Prentice, R.L.4
  • 228
    • 84878699293 scopus 로고    scopus 로고
    • The role of gut microbiota in the pathogenesis of colorectal cancer
    • Q.Zhu, R.Gao, W.Wu, and H.Qin, (2013). The role of gut microbiota in the pathogenesis of colorectal cancer. Tumor Biol. 34:1285–1300.
    • (2013) Tumor Biol , vol.34 , pp. 1285-1300
    • Zhu, Q.1    Gao, R.2    Wu, W.3    Qin, H.4
  • 230
    • 84859157322 scopus 로고    scopus 로고
    • Red meat consumption and cancer: Reasons to suspect involvement of bovine infectious factors in colorectal cancer
    • H.zur Hausen, (2012). Red meat consumption and cancer:Reasons to suspect involvement of bovine infectious factors in colorectal cancer. Int. J. Cancer 130:2475–2483.
    • (2012) Int. J. Cancer , vol.130 , pp. 2475-2483
    • zur Hausen, H.1


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