메뉴 건너뛰기




Volumn 6, Issue 8, 2008, Pages

Polycyclic Aromatic Hydrocarbons in Food - Scientific Opinion of the Panel on Contaminants in the Food Chain
[No Author Info available]

Author keywords

benchmark dose lower confidence limit (BMDL); exposure; food; indicators; margin of exposure (MOE); occurrence; Polycyclic aromatic hydrocarbons (PAHs); risk assessment; toxic equivalency factor (TEF)

Indexed keywords


EID: 85076327714     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2008.724     Document Type: Article
Times cited : (301)

References (159)
  • 1
    • 2942598063 scopus 로고    scopus 로고
    • Cytochrome P450 gene polymorphism and cancer
    • Agundez, J.A. 2004. Cytochrome P450 gene polymorphism and cancer. Curr. Drug Metab. 5: 211–224.
    • (2004) Curr. Drug Metab , vol.5 , pp. 211-224
    • Agundez, J.A.1
  • 2
    • 0036955117 scopus 로고    scopus 로고
    • CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation
    • Alekandrov, K., Cascorbi, I., Rojas, M., Bouvier, G., Kriek, E. and Bartsch, H. 2002. CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. Carcinogenesis 23: 1969–1977.
    • (2002) Carcinogenesis , vol.23 , pp. 1969-1977
    • Alekandrov, K.1    Cascorbi, I.2    Rojas, M.3    Bouvier, G.4    Kriek, E.5    Bartsch, H.6
  • 3
    • 3142652566 scopus 로고    scopus 로고
    • Levels of benzo[a]pyrene (BaP) in “Mozzarella di Bufala Campana” cheese smoked according to different procedures
    • Anastasio, A., Mercogliano, R., Vollano, L., Pepe, T. and Cortesi, M.L. 2004. Levels of benzo[a]pyrene (BaP) in “Mozzarella di Bufala Campana” cheese smoked according to different procedures. J. Agric. Food Chem. 52: 4452–4455.
    • (2004) J. Agric. Food Chem , vol.52 , pp. 4452-4455
    • Anastasio, A.1    Mercogliano, R.2    Vollano, L.3    Pepe, T.4    Cortesi, M.L.5
  • 4
    • 0030907682 scopus 로고    scopus 로고
    • Occupational exposure to polycyclic aromatic hydrocarbons in a graphite-electrode producing plant: biological monitoring of 1-hydroxypyrene and monohydroxylated metabolites of phenanthrene
    • Angerer, J., Mannschreck, C. and Güdel, J. 1997. Occupational exposure to polycyclic aromatic hydrocarbons in a graphite-electrode producing plant: biological monitoring of 1-hydroxypyrene and monohydroxylated metabolites of phenanthrene. Int. Arch. Occup. Environ. Helath 69: 323–331.
    • (1997) Int. Arch. Occup. Environ. Helath , vol.69 , pp. 323-331
    • Angerer, J.1    Mannschreck, C.2    Güdel, J.3
  • 5
    • 0003440508 scopus 로고
    • U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry
    • ATSDR (Agency for Toxic Substances and Disease Registry). 1995. Toxicological profile for polycyclic aromatic hydrocarbons. U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry. www.atsdr.cdc.gov/toxprofiles/tp69.pdf.
    • (1995) Toxicological profile for polycyclic aromatic hydrocarbons
  • 6
    • 0001636928 scopus 로고    scopus 로고
    • Bowden, G.T., Fisher, S.M., ed.)., Elsevier, Oxford, UK
    • Baird, W.M. and Ralston, S.L. 1997. In: Comprehensive Toxicology (Bowden, G.T. and Fisher, S.M., ed.). Elsevier, Oxford, UK, pp. 171–200.
    • (1997) Comprehensive Toxicology , pp. 171-200
    • Baird, W.M.1    Ralston, S.L.2
  • 9
    • 0026564746 scopus 로고
    • An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbon to urinary elimination of 1-hydroxypyrene
    • Buckley, T.J. and Lioy, P.J. 1992. An examination of the time course from human dietary exposure to polycyclic aromatic hydrocarbon to urinary elimination of 1-hydroxypyrene. Br. J. Ind. Med. 49: 113–124.
    • (1992) Br. J. Ind. Med , vol.49 , pp. 113-124
    • Buckley, T.J.1    Lioy, P.J.2
  • 10
    • 0019350961 scopus 로고
    • Reactivity of Polycyclic aromatic hydrocarbons adsorbed on soot particles
    • Butler, J.D. and Crossley, P. 1981. Reactivity of Polycyclic aromatic hydrocarbons adsorbed on soot particles. Atmos. Environ. 15: 91–94
    • (1981) Atmos. Environ , vol.15 , pp. 91-94
    • Butler, J.D.1    Crossley, P.2
  • 11
    • 0031873379 scopus 로고    scopus 로고
    • Ah receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms
    • Bock, K.W., Gschaidmeier, H., Heel, H., Lehmköster, T., Münzel, P.A., Raschko, F. and Bock Hennig, B. 1998. Ah receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms. Adv. Enzyme Regul. 38: 207–222.
    • (1998) Adv. Enzyme Regul , vol.38 , pp. 207-222
    • Bock, K.W.1    Gschaidmeier, H.2    Heel, H.3    Lehmköster, T.4    Münzel, P.A.5    Raschko, F.6    Bock Hennig, B.7
  • 12
    • 0030906628 scopus 로고    scopus 로고
    • Urinary excretion of benzo(a)-pyrene metabolites following intravenous, oral, and cutaneous benzo(a)pyrene administration
    • Bouchard, M. and Viau, C. 1997. Urinary excretion of benzo(a)-pyrene metabolites following intravenous, oral, and cutaneous benzo(a)pyrene administration. Can. J. Physiol. Pharmacol. 75: 185–192.
    • (1997) Can. J. Physiol. Pharmacol , vol.75 , pp. 185-192
    • Bouchard, M.1    Viau, C.2
  • 13
    • 0008207316 scopus 로고
    • Technical Resources, Inc., Contract 68-01-0022, for Office of Emergency and Remedial Response, Office of Solid Waste and Emergency Response, U.S. Environmental Protection Agency, Office of Pesticides, Pollution Prevention and Toxic Substances (OPPTS)
    • Brown, R. and Mittelsman, A. 1993. Evaluation of existing methods to rank the relative carcinogenicity of polycyclic aromatic compounds (PAH), Draft. Technical Resources, Inc., Contract No. 68-01-0022, for Office of Emergency and Remedial Response, Office of Solid Waste and Emergency Response, U.S. Environmental Protection Agency, Office of Pesticides, Pollution Prevention and Toxic Substances (OPPTS).
    • (1993) Evaluation of existing methods to rank the relative carcinogenicity of polycyclic aromatic compounds (PAH), Draft
    • Brown, R.1    Mittelsman, A.2
  • 14
    • 0029080079 scopus 로고
    • Central role of radical cations in metabolic activation of polyyclic aromatic hydrocarbons
    • Cavalieri, E.L. and Rogan, E.G. 1995. Central role of radical cations in metabolic activation of polyyclic aromatic hydrocarbons. Xenobiotica 25: 677–688.
    • (1995) Xenobiotica , vol.25 , pp. 677-688
    • Cavalieri, E.L.1    Rogan, E.G.2
  • 16
    • 0041919632 scopus 로고    scopus 로고
    • Intestinal absorption of 14C from 14C-phenanthrene, 14C-benzo(a)pyrene and 14Ctetrachlorodibenzo-para-dioxin: Approaches with the Caco-2 cell line and portal absorption measurements in growing pigs
    • Cavret, S., Laurent C., Feidt, C., Laurent, F. and Rychen, G. 2003. Intestinal absorption of 14C from 14C-phenanthrene, 14C-benzo(a)pyrene and 14Ctetrachlorodibenzo-para-dioxin: Approaches with the Caco-2 cell line and portal absorption measurements in growing pigs. Reprod. Nutr. Dev. 43: 145–154.
    • (2003) Reprod. Nutr. Dev , vol.43 , pp. 145-154
    • Cavret, S.1    Laurent, C.2    Feidt, C.3    Laurent, F.4    Rychen, G.5
  • 17
    • 38049141713 scopus 로고    scopus 로고
    • Impact of toasting oak barrels on the presence of polycyclic aromatic hydrocarbons in wine
    • Chatonnet, P. and Escobessa, J. 2007. Impact of toasting oak barrels on the presence of polycyclic aromatic hydrocarbons in wine. J. Agric. Food Chem. 55: 10351–10358.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 10351-10358
    • Chatonnet, P.1    Escobessa, J.2
  • 18
    • 0001169287 scopus 로고    scopus 로고
    • Formation of polycyclic aromatic hydrocarbons during processing of duck meat
    • Chen, B.H. and Lin, Y.S. 1997. Formation of polycyclic aromatic hydrocarbons during processing of duck meat. J. Agric. Food Chem. 45: 1394–1403.
    • (1997) J. Agric. Food Chem , vol.45 , pp. 1394-1403
    • Chen, B.H.1    Lin, Y.S.2
  • 19
    • 0021672854 scopus 로고
    • An improved procedure for low-dose carcinogenic risk assessment from animal data
    • Crump, K.S. 1984. An improved procedure for low-dose carcinogenic risk assessment from animal data. J. Environ. Pathol. Toxicol. Oncol. 5: 339–348.
    • (1984) J. Environ. Pathol. Toxicol. Oncol , vol.5 , pp. 339-348
    • Crump, K.S.1
  • 20
    • 0031869266 scopus 로고    scopus 로고
    • A comparison of the tumours induced by coal tar and benzo[a]pyrene in a 2-year bioassay
    • Culp, S.J., Gaylor, D.W., Sheldon, W.G., Goldstein, L.S. and Beland, F.A. 1998. A comparison of the tumours induced by coal tar and benzo[a]pyrene in a 2-year bioassay. Carcinogenesis, 19: 117–124.
    • (1998) Carcinogenesis , vol.19 , pp. 117-124
    • Culp, S.J.1    Gaylor, D.W.2    Sheldon, W.G.3    Goldstein, L.S.4    Beland, F.A.5
  • 21
    • 0034212585 scopus 로고    scopus 로고
    • Evaluation of fecal mutagenicity and colorectal cancer risk
    • de Kok, T.M.C.M. and van Maanen, J.M.S. 2000. Evaluation of fecal mutagenicity and colorectal cancer risk. Mutat. Res. 463: 53–101.
    • (2000) Mutat. Res , vol.463 , pp. 53-101
    • de Kok, T.M.C.M.1    van Maanen, J.M.S.2
  • 22
    • 0008726959 scopus 로고
    • Rapid determination of benzo[a]pyrene in roasted coffee and coffee brew by high performance liquid chromatography with fluorescence detection
    • de Kruijf, N., Schouten, T. and Van der Stegen, G.H.D. 1987. Rapid determination of benzo[a]pyrene in roasted coffee and coffee brew by high performance liquid chromatography with fluorescence detection. J. Agric. Food Chem. 35: 545–549.
    • (1987) J. Agric. Food Chem , vol.35 , pp. 545-549
    • de Kruijf, N.1    Schouten, T.2    Van der Stegen, G.H.D.3
  • 26
    • 85078393312 scopus 로고    scopus 로고
    • ed.)., American Chemical Society Press, Washington DC
    • . American Chemical Society Press, Washington DC, pp. 41–163.
    • Searle, C.E.1
  • 27
    • 0023236470 scopus 로고
    • Optically active benzo[c]phenanthrene diol-epoxides bind extensively to adenine in DNA
    • Dipple, A., Pigott, P.A., Agarwal, S.K., Yagi, H., Sayer, J.M. and Jerina, D.M. 1987. Optically active benzo[c]phenanthrene diol-epoxides bind extensively to adenine in DNA. Nature 327: 535–536.
    • (1987) Nature , vol.327 , pp. 535-536
    • Dipple, A.1    Pigott, P.A.2    Agarwal, S.K.3    Yagi, H.4    Sayer, J.M.5    Jerina, D.M.6
  • 29
    • 85078368832 scopus 로고    scopus 로고
    • Outcome of the expert group meeting on 3 October on ways to prevent contamination of olive residue oil and other oils with polycyclic aromatic hydrocarbons (PAH)
    • Summary record of the 85th meeting of the Standing Committee on Foodstuffs, 25th October 2001
    • EC (European Commission). 2001. Outcome of the expert group meeting on 3 October on ways to prevent contamination of olive residue oil and other oils with polycyclic aromatic hydrocarbons (PAH). Summary record of the 85th meeting of the Standing Committee on Foodstuffs, 25th October 2001, agenda item 9. europa.eu.int/comm/food/fs/rc/scfs/rap09_en.pdf
    • (2001) agenda item 9
  • 32
    • 85060723513 scopus 로고    scopus 로고
    • Opinion of the Scientific Committee on a request from EFSA related to a harmonized approach for risk assessment of substances which are both genotoxic and carcinogenic
    • EFSA (European Food Safety Authority). 2005a. Opinion of the Scientific Committee on a request from EFSA related to a harmonized approach for risk assessment of substances which are both genotoxic and carcinogenic. The EFSA Journal 282: 1–31. www.efsa.europa.eu/EFSA/Scientific_Opinion/sc_op_ej282_gentox_en3,0.pdf
    • (2005) The EFSA Journal , vol.282 , pp. 1-31
  • 33
    • 85078366948 scopus 로고    scopus 로고
    • EFSA Scientific Colloquium Summary Report
    • EFSA (European Food Safety Authority). 2005b. European Food Consumption Database: Current and medium to long-term strategies. EFSA Scientific Colloquium Summary Report. www.efsa.europa.eu/EFSA/Scientific_Document/Sc_Colloque_no3_European_food_consumption_database,0.pdf
    • (2005) European Food Consumption Database: Current and medium to long-term strategies
  • 35
    • 84878937191 scopus 로고    scopus 로고
    • A report from the Unit of data Collection and Exposure on a Request from the European Commission. EFSA/DATEX/002
    • EFSA (European Food Safety Authority). 2007. Findings of the EFSA data collection on polycyclic aromatic hydrocarbons in food. A report from the Unit of data Collection and Exposure on a Request from the European Commission. EFSA/DATEX/002. www.efsa.europa.eu/EFSA/Scientific_Document/datex_report_pah.pdf.
    • (2007) Findings of the EFSA data collection on polycyclic aromatic hydrocarbons in food
  • 37
    • 33847743443 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver
    • Elovaara, E., Mikkola, J., Stockmann-Juvala, H., Luukkanen, L., Keski-Hynnilä, H., Kostiainen, R., Pasanen, M., Pelkonen, O. and Vainio, H. 2007. Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver. Arch. Toxicol. 81: 169–182.
    • (2007) Arch. Toxicol , vol.81 , pp. 169-182
    • Elovaara, E.1    Mikkola, J.2    Stockmann-Juvala, H.3    Luukkanen, L.4    Keski-Hynnilä, H.5    Kostiainen, R.6    Pasanen, M.7    Pelkonen, O.8    Vainio, H.9
  • 38
    • 85078377029 scopus 로고    scopus 로고
    • Heavy metals and POPs within the EMEP region 1999
    • EMEP/CCC-Report 9/2001., PO Box 100, NO-2027 Kjeller, Norway
    • EMEP (Co-operative programme for monitoring and evaluation of the long-range transmissions of air pollutants in Europe). 2001. Heavy metals and POPs within the EMEP region 1999. EMEP/CCC-Report 9/2001. Norwegian Institute for Air Research PO Box 100, NO-2027 Kjeller, Norway.
    • (2001) Norwegian Institute for Air Research
  • 39
    • 0027504451 scopus 로고
    • Relationships of polycyclic aromatic hydrocarbon yields with particulate matter (water and nicotine free) yields in mainstream and sidestream cigarette smoke
    • Evans, W. H., Thomas, N. C., Boardman, M. C. and Nash, S. J. 1993. Relationships of polycyclic aromatic hydrocarbon yields with particulate matter (water and nicotine free) yields in mainstream and sidestream cigarette smoke. Sci. Tot. Environ. 136 (1–2): 101–109.
    • (1993) Sci. Tot. Environ , vol.136 , Issue.1-2 , pp. 101-109
    • Evans, W.H.1    Thomas, N.C.2    Boardman, M.C.3    Nash, S.J.4
  • 40
    • 33847214575 scopus 로고    scopus 로고
    • Higher urine 1-hydroxypyrene glucuronide (1-OHPG) is associated with tobacco smoke exposure and drinking mate in healthy subjects from Rio Grande do Sul, Brazil
    • Fagundes, R.B., Abnet, C.C., Strickland, P.T., Kamangar, F., Roth, M.J., Taylor, P.R. and Dawsey, S.M. 2006. Higher urine 1-hydroxypyrene glucuronide (1-OHPG) is associated with tobacco smoke exposure and drinking mate in healthy subjects from Rio Grande do Sul, Brazil. BMC Cancer, 6, 139.
    • (2006) BMC Cancer , vol.6 , pp. 139
    • Fagundes, R.B.1    Abnet, C.C.2    Strickland, P.T.3    Kamangar, F.4    Roth, M.J.5    Taylor, P.R.6    Dawsey, S.M.7
  • 41
    • 0142010683 scopus 로고    scopus 로고
    • The Benchmark dose methodReview of available models, and recommendations for application in health risk assessment
    • Falk Filipsson, A.F., Sand, S., Nilsson, J. and Victorin, K. 2003. The Benchmark dose methodReview of available models, and recommendations for application in health risk assessment. Crit. Rev. Toxicol. 33 (5): 505–542.
    • (2003) Crit. Rev. Toxicol , vol.33 , Issue.5 , pp. 505-542
    • Falk Filipsson, A.F.1    Sand, S.2    Nilsson, J.3    Victorin, K.4
  • 42
    • 33845344543 scopus 로고    scopus 로고
    • FAO, Rome, Italy
    • FAO (Food and Agriculture Organization of the United Nations). 2004. The state of world fisheries and aquaculture. FAO, Rome, Italy. www.fao.org/DOCREP/007/y5600e/y5600e05.htm#P1257_75403.
    • (2004) The state of world fisheries and aquaculture
  • 43
    • 70249128936 scopus 로고    scopus 로고
    • Joint FAO/WHO Expert Committee on Food Additives (JECFA)
    • Sixty-fourth meeting, Rome, 8–17 February 2005
    • FAO/WHO (Food and Agriculture Organization of the United Nations/World Health Organization). 2005. Joint FAO/WHO Expert Committee on Food Additives (JECFA). Sixty-fourth meeting, Rome, 8–17 February 2005. Summary and Conclusions. www.who.int/ipcs/food/jecfa/summaries/summary_report_64_final.pdf
    • (2005) Summary and Conclusions
  • 44
    • 85078396914 scopus 로고    scopus 로고
    • Prepared by the Sixty-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). WHO Food Additives Series 55; FAO Food and Nutrition Paper 82; World Health Organization WHO, 2006; Food and Agriculture Organization of the United Nations FAO, 2006
    • FAO/WHO (Food and Agriculture Organization of the United Nations/World Health Organization). 2006. Safety evaluation of certain contaminants in food. Prepared by the Sixty-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). WHO Food Additives Series: 55; FAO Food and Nutrition Paper 82; World Health Organization WHO, 2006; Food and Agriculture Organization of the United Nations FAO, 2006. whqlibdoc.who.int/publications/2006/9241660554_eng.pdf
    • (2006) Safety evaluation of certain contaminants in food
  • 45
    • 0031550531 scopus 로고    scopus 로고
    • 7-Sulfooxymethyl-12-methylbenz[a]anthracene is an exceptionally reactive electrophilic mutagen and ultimate carcinogen
    • Flesher, J.W., Horn, J. and Lehner, A.F. 1997. 7-Sulfooxymethyl-12-methylbenz[a]anthracene is an exceptionally reactive electrophilic mutagen and ultimate carcinogen. Biochem. Biophys. Res. Commun. 231: 144–148.
    • (1997) Biochem. Biophys. Res. Commun , vol.231 , pp. 144-148
    • Flesher, J.W.1    Horn, J.2    Lehner, A.F.3
  • 48
    • 41749111766 scopus 로고    scopus 로고
    • 3-Hydroxybenzo[a]pyrene in the urine of workers with occupational exposure to polycyclic aromatic hydrocarbons in different industries
    • Förster, K., Preuss, R., Rossbach, B., Brüning, T., Angerer, J. and Simon, P. 2008. 3-Hydroxybenzo[a]pyrene in the urine of workers with occupational exposure to polycyclic aromatic hydrocarbons in different industries. Occup. Environ. Med. 65: 224–229.
    • (2008) Occup. Environ. Med , vol.65 , pp. 224-229
    • Förster, K.1    Preuss, R.2    Rossbach, B.3    Brüning, T.4    Angerer, J.5    Simon, P.6
  • 49
    • 34447302544 scopus 로고    scopus 로고
    • Analysis of polycyclic aromatic hydrocarbons in vegetable oils combining gel permeation chromatography with solid-phase extraction clean-up
    • Fromberg, A., Højgård, A. and Duedahl-Olesen, L. 2007. Analysis of polycyclic aromatic hydrocarbons in vegetable oils combining gel permeation chromatography with solid-phase extraction clean-up. Food Addit. Contam. 24 (7): 758–767.
    • (2007) Food Addit. Contam , vol.24 , Issue.7 , pp. 758-767
    • Fromberg, A.1    Højgård, A.2    Duedahl-Olesen, L.3
  • 50
    • 34247606582 scopus 로고    scopus 로고
    • Profiles of polycyclic aromatic hydrocarbons in Brazilian sugar cane spirits: Discrimination between cachacas produced from nonburned and burned sugar cane crops
    • Galinaro, C.A., Cardoso, D.R. and Franco, D.W. 2007. Profiles of polycyclic aromatic hydrocarbons in Brazilian sugar cane spirits: Discrimination between cachacas produced from nonburned and burned sugar cane crops. J. Agric. Food Chem. 55: 3141–3147.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 3141-3147
    • Galinaro, C.A.1    Cardoso, D.R.2    Franco, D.W.3
  • 51
    • 7044233274 scopus 로고    scopus 로고
    • Minimal clean-up and rapid determination of polycyclic aromatic hydrocarbons in instant coffee
    • García-Falcón, M.S., Cancho-Grande, B. and Simal-Gándara, J. 2005. Minimal clean-up and rapid determination of polycyclic aromatic hydrocarbons in instant coffee. Food Chem. 90: 643–647.
    • (2005) Food Chem , vol.90 , pp. 643-647
    • García-Falcón, M.S.1    Cancho-Grande, B.2    Simal-Gándara, J.3
  • 54
    • 27744549724 scopus 로고    scopus 로고
    • Determination of polycyclic aromatic hydrocarbons in alcoholic drinks and the identification of their potential sources
    • García Falcón, M. S. and Simal-Gandara, J. 2005. Determination of polycyclic aromatic hydrocarbons in alcoholic drinks and the identification of their potential sources. Food Addit. Contam. 22: 791–797.
    • (2005) Food Addit. Contam , vol.22 , pp. 791-797
    • García Falcón, M.S.1    Simal-Gandara, J.2
  • 55
    • 85005586835 scopus 로고
    • The chemistry of smoked foods: a review
    • Gilbert, J., and Knowles, M.E. 1975. The chemistry of smoked foods: a review. J. Food Technol. 10: 245–261.
    • (1975) J. Food Technol , vol.10 , pp. 245-261
    • Gilbert, J.1    Knowles, M.E.2
  • 56
    • 0032603791 scopus 로고    scopus 로고
    • A nomenclature system for metabolic gene polymorphisms
    • Garte, S. and Crosti, F. 1999. A nomenclature system for metabolic gene polymorphisms. IARC Sci. Publ. 148: 5–12.
    • (1999) IARC Sci. Publ , vol.148 , pp. 5-12
    • Garte, S.1    Crosti, F.2
  • 57
    • 0019074870 scopus 로고
    • Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role andregulation of mixed-function oxidases and related enzymes
    • Gelboin, H.V. 1980. Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role andregulation of mixed-function oxidases and related enzymes. Physiol. Rev. 60: 1107–1166.
    • (1980) Physiol. Rev , vol.60 , pp. 1107-1166
    • Gelboin, H.V.1
  • 58
    • 0034802596 scopus 로고    scopus 로고
    • To BaP or not to BaP? That is the question
    • Goldstein, L.S. 2001. To BaP or not to BaP? That is the question. Environ. Health Perspec. 109 (8): A356–357.
    • (2001) Environ. Health Perspec , vol.109 , Issue.8 , pp. A356-357
    • Goldstein, L.S.1
  • 60
    • 0021889877 scopus 로고
    • Polycyclic aromatic hydrocarbons in New Jersey (USA): A comparison of winter and summer concentrations over a two-year period
    • Greenberg, A., Darack, F. and Harkov, R. 1985. Polycyclic aromatic hydrocarbons in New Jersey (USA): A comparison of winter and summer concentrations over a two-year period. Atmos. Environ. 19: 1325–1340.
    • (1985) Atmos. Environ , vol.19 , pp. 1325-1340
    • Greenberg, A.1    Darack, F.2    Harkov, R.3
  • 61
    • 0036989658 scopus 로고    scopus 로고
    • [14C] Milk, urine and faeces excretion kinetics in lactating goats after an oral administration of [14C] polycyclic aromatic hydrocarbons
    • Grova, N., Feidt, C., Laurent, C. and Rychen, G. 2002. [14C] Milk, urine and faeces excretion kinetics in lactating goats after an oral administration of [14C] polycyclic aromatic hydrocarbons. Int. Dairy J. 12: 1025–1031.
    • (2002) Int. Dairy J , vol.12 , pp. 1025-1031
    • Grova, N.1    Feidt, C.2    Laurent, C.3    Rychen, G.4
  • 62
    • 3142675185 scopus 로고    scopus 로고
    • Occurrence of polycyclic aromatic hydrocarbons in smoked cheese
    • Guillén, M.D. and Sopelana, P. 2004. Occurrence of polycyclic aromatic hydrocarbons in smoked cheese. J. Dairy Sci. 87: 556–564.
    • (2004) J. Dairy Sci , vol.87 , pp. 556-564
    • Guillén, M.D.1    Sopelana, P.2
  • 63
    • 0343114432 scopus 로고    scopus 로고
    • Determination of polycyclic aromatic hydrocarbons in commercial liquid smoke flavorings of different compositions by gas chromatography-mass spectrometry
    • Guillén, M.D., Sopelana, P. and Partearroyo, M.A. 2000. Determination of polycyclic aromatic hydrocarbons in commercial liquid smoke flavorings of different compositions by gas chromatography-mass spectrometry. J. Agric. Food Chem. 48: 126–131.
    • (2000) J. Agric. Food Chem , vol.48 , pp. 126-131
    • Guillén, M.D.1    Sopelana, P.2    Partearroyo, M.A.3
  • 65
    • 0000149592 scopus 로고
    • Polycyclic aromatic hydrocarbons: metabolisim, activation and tumor initiation
    • Cooper, C.S., Grover, P.L., ed.)., Springer- Verlag, Heidelberg
    • Hall, M. and Grover, P.L. 1990. Polycyclic aromatic hydrocarbons: metabolisim, activation and tumor initiation. In: Chemical Carcinogenesis and Mutagenesis Vol. 1. (Cooper, C.S. and Grover, P.L., ed.). Springer- Verlag, Heidelberg, pp. 327–372.
    • (1990) In: Chemical Carcinogenesis and Mutagenesis Vol , vol.1 , pp. 327-372
    • Hall, M.1    Grover, P.L.2
  • 67
    • 0021795425 scopus 로고
    • Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin
    • Hecht, S.S., Radok, L., Amin, S., Huie, K., Melikian, A.A., Hoffmann, D., Pataki, J. and Harvey, R.G. 1985. Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin. Cancer Res. 45: 1449–1452.
    • (1985) Cancer Res , vol.45 , pp. 1449-1452
    • Hecht, S.S.1    Radok, L.2    Amin, S.3    Huie, K.4    Melikian, A.A.5    Hoffmann, D.6    Pataki, J.7    Harvey, R.G.8
  • 68
    • 0023140390 scopus 로고
    • Determination of benzo[a]pyrene in roasted coffee and coffee brews by HPLC with fluorescence detection
    • Hischenhuber, C. and Stijve, T. 1987. Determination of benzo[a]pyrene in roasted coffee and coffee brews by HPLC with fluorescence detection. Dtsch. Lebensm. Rundsch. 83: 1–4.
    • (1987) Dtsch. Lebensm. Rundsch , vol.83 , pp. 1-4
    • Hischenhuber, C.1    Stijve, T.2
  • 69
    • 13944258939 scopus 로고    scopus 로고
    • Determination of polycyclic aromatic hydrocarbons in coffee brew using solid-phase extraction
    • Houessou, J.K., Benac, C., Delteil, C. and Camel, V. 2005. Determination of polycyclic aromatic hydrocarbons in coffee brew using solid-phase extraction. J. Agric. Food Chem. 53: 871–879.
    • (2005) J. Agric. Food Chem , vol.53 , pp. 871-879
    • Houessou, J.K.1    Benac, C.2    Delteil, C.3    Camel, V.4
  • 70
    • 36749081683 scopus 로고    scopus 로고
    • Effect of Roasting Conditions on the Polycyclic Aromatic Hydrocarbon Content in Ground Arabica Coffee and Coffee Brew
    • Houessou, J.K., Maloug, S., Leveque, A.-S., Delteil, C., Heyd, B. and Camel, V. 2007. Effect of Roasting Conditions on the Polycyclic Aromatic Hydrocarbon Content in Ground Arabica Coffee and Coffee Brew. J. Agric. Food Chem. 55: 9719–9726.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 9719-9726
    • Houessou, J.K.1    Maloug, S.2    Leveque, A.-S.3    Delteil, C.4    Heyd, B.5    Camel, V.6
  • 71
    • 45549087098 scopus 로고    scopus 로고
    • Modeling the formation of some polycyclic aromatic hydrocarbons during the roasting of Arabica Coffee samples
    • Houessou, J.K., Goujot, D., Heyd, B. and Camel, V. 2008. Modeling the formation of some polycyclic aromatic hydrocarbons during the roasting of Arabica Coffee samples. J. Agric. Food Chem. 56: 3648–3656.
    • (2008) J. Agric. Food Chem , vol.56 , pp. 3648-3656
    • Houessou, J.K.1    Goujot, D.2    Heyd, B.3    Camel, V.4
  • 73
    • 0041692931 scopus 로고    scopus 로고
    • Control of food safety hazards during cold-smoked fish processing
    • Jahncke, M.L. and Herman, D. 2001. Control of food safety hazards during cold-smoked fish processing. J. Food Sci. – Supplement to Vol. 66 (7): S1104–S1112.
    • (2001) J. Food Sci. – Supplement to Vol , vol.66 , Issue.7 , pp. S1104-S1112
    • Jahncke, M.L.1    Herman, D.2
  • 74
    • 0025341528 scopus 로고
    • Ambient and biological monitoring of cokeoven workers: determinants of the internal dose of polycyclic aromatic hydrocarbons
    • Jongeneelen, F.J., van Leeuwen F.E. and Oosterink, S. 1990. Ambient and biological monitoring of cokeoven workers: determinants of the internal dose of polycyclic aromatic hydrocarbons. Br. J. Ind. Med. 47: 454–461.
    • (1990) Br. J. Ind. Med , vol.47 , pp. 454-461
    • Jongeneelen, F.J.1    van Leeuwen, F.E.2    Oosterink, S.3
  • 75
    • 37349045953 scopus 로고    scopus 로고
    • Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats
    • Kang, H.G., Jeong, S.H., Cho, M.H., and Cho, J.H. 2007. Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats. J. Vet. Sci. 8: 361–368.
    • (2007) J. Vet. Sci , vol.8 , pp. 361-368
    • Kang, H.G.1    Jeong, S.H.2    Cho, M.H.3    Cho, J.H.4
  • 76
    • 0030171029 scopus 로고    scopus 로고
    • Determination of polycyclic aromatic hydrocarbons in smoked fishery products from different smoking kilns
    • Karl, H. and Leinemann, M. 1996. Determination of polycyclic aromatic hydrocarbons in smoked fishery products from different smoking kilns. Z. Lebensm. Unters. Forsch. 202: 458–464.
    • (1996) Z. Lebensm. Unters. Forsch , vol.202 , pp. 458-464
    • Karl, H.1    Leinemann, M.2
  • 77
    • 0028910932 scopus 로고
    • Determination of benzo(a)pyrene in total particulate matter of virginia and black tobacco smoke by HPLC with fluorimetric detection
    • Kayali, M. N. and Rubio-Barroso, S. 1995. Determination of benzo(a)pyrene in total particulate matter of virginia and black tobacco smoke by HPLC with fluorimetric detection. J. Liquid Chrom. Rel. Technol. 18 (8): 1617–1632.
    • (1995) J. Liquid Chrom. Rel. Technol , vol.18 , Issue.8 , pp. 1617-1632
    • Kayali, M.N.1    Rubio-Barroso, S.2
  • 78
    • 0033014177 scopus 로고    scopus 로고
    • A new method for the determination of selected PAHs in coffee brew samples by HPLC with fluorimetric detection and solid-phase extraction
    • Kayali-Sayadi, M.N., Rubio-Barroso, S., Cuesta-Jimenez, M.P. and Polo-Diez, L.M. 1999. A new method for the determination of selected PAHs in coffee brew samples by HPLC with fluorimetric detection and solid-phase extraction. J. Liq. Chrom. Rel. Technol. 22 (4): 615–627.
    • (1999) J. Liq. Chrom. Rel. Technol , vol.22 , Issue.4 , pp. 615-627
    • Kayali-Sayadi, M.N.1    Rubio-Barroso, S.2    Cuesta-Jimenez, M.P.3    Polo-Diez, L.M.4
  • 81
    • 0024407702 scopus 로고
    • Carcinogenic risk assessment of complex mixtures
    • Krewski, D., Thorslund, T. and Withey, J. 1989. Carcinogenic risk assessment of complex mixtures. Toxicol. Ind. Health. 5: 851–867.
    • (1989) Toxicol. Ind. Health , vol.5 , pp. 851-867
    • Krewski, D.1    Thorslund, T.2    Withey, J.3
  • 82
    • 2042452229 scopus 로고    scopus 로고
    • Tumourigenic effects in Wistar rats orally administered benzo[a]pyrene for two years (gavage studies)
    • Implications for human cancer risks associated with oral exposure to polycyclic aromatic hydrocarbons. National Institute of Public Health and the Environment, RIVM November 2001
    • Kroese, E.D., Muller, J.J.A., Mohn, G.R., Dortant, P.M. and Wester, P.W. 2001. Tumourigenic effects in Wistar rats orally administered benzo[a]pyrene for two years (gavage studies). Implications for human cancer risks associated with oral exposure to polycyclic aromatic hydrocarbons. National Institute of Public Health and the Environment, RIVM Report no. 658603 010, November 2001, Bilthoven.
    • (2001) Bilthoven
    • Kroese, E.D.1    Muller, J.J.A.2    Mohn, G.R.3    Dortant, P.M.4    Wester, P.W.5
  • 83
    • 0030292266 scopus 로고    scopus 로고
    • Confusion of concepts in mixture toxicology
    • Könemann, W.H. and Pieters, M.N. 1996. Confusion of concepts in mixture toxicology. Food Chem. Toxicol. 34: 1025–1031.
    • (1996) Food Chem. Toxicol , vol.34 , pp. 1025-1031
    • Könemann, W.H.1    Pieters, M.N.2
  • 84
    • 0023786340 scopus 로고
    • Intestinal absorption of carcinogenic hydrocarbons
    • Laher, J. M. and Barrowman, J. A. 1987. Intestinal absorption of carcinogenic hydrocarbons. Ann. N. Y. Acad. Sci. 534: 565–574.
    • (1987) Ann. N. Y. Acad. Sci , vol.534 , pp. 565-574
    • Laher, J.M.1    Barrowman, J.A.2
  • 85
    • 34547684114 scopus 로고    scopus 로고
    • Milk and urine excretion of polycyclic aromatic hydrocarbons and their hydroxylated metabolites after a single oral administration in ruminants
    • Lapole, D., Rychen, G., Grova, N., Monteau, F., Le Bizec, B. and Feidt, C. 2007. Milk and urine excretion of polycyclic aromatic hydrocarbons and their hydroxylated metabolites after a single oral administration in ruminants. J. Dairy Sci. 90: 2624–2629.
    • (2007) J. Dairy Sci , vol.90 , pp. 2624-2629
    • Lapole, D.1    Rychen, G.2    Grova, N.3    Monteau, F.4    Le Bizec, B.5    Feidt, C.6
  • 86
    • 0002854753 scopus 로고    scopus 로고
    • Chemical Carcinogens
    • Hester, R.E., Harrison, R.M., ed.)., The Royal Society of Chemical, Cambridge
    • Larsen, J.C. and Larsen, P.B. 1998. Chemical Carcinogens. In: Air Pollution and Health (Hester, R.E. and Harrison, R.M., ed.). Issues in Environmental Sciences and Technology, 10, The Royal Society of Chemical, Cambridge.
    • (1998) Issues in Environmental Sciences and Technology, 10
    • Larsen, J.C.1    Larsen, P.B.2
  • 89
    • 0018139369 scopus 로고
    • Evidence that benzo(a)anthracene 3,4-diol-1, 2-epoxide is an ultimate carcinogen on mouse skin
    • Levin, W., Thakker, D.R., Wood, A.W., Chang, R.L., Lehr, R.E., Jerina, D.M. and Conney, A.H. 1978. Evidence that benzo(a)anthracene 3,4-diol-1, 2-epoxide is an ultimate carcinogen on mouse skin. Cancer Res. 38: 1705–1710.
    • (1978) Cancer Res , vol.38 , pp. 1705-1710
    • Levin, W.1    Thakker, D.R.2    Wood, A.W.3    Chang, R.L.4    Lehr, R.E.5    Jerina, D.M.6    Conney, A.H.7
  • 90
    • 0014119353 scopus 로고
    • Production of carcinogenic polynuclear hydrocarbons in the cooking of food
    • Lijinsky, W. and Ross, A.E. 1967. Production of carcinogenic polynuclear hydrocarbons in the cooking of food. Food Cosmet. Toxicol. 5: 343–347.
    • (1967) Food Cosmet. Toxicol , vol.5 , pp. 343-347
    • Lijinsky, W.1    Ross, A.E.2
  • 91
    • 0018713653 scopus 로고
    • Determination of benzo[a]pyrene in smoked, cooked and toasted food products
    • Lintas, C., de Matthaeis, M.C. and Merli, F. 1979. Determination of benzo[a]pyrene in smoked, cooked and toasted food products. Food Cosmet. Toxicol. 17: 325–328.
    • (1979) Food Cosmet. Toxicol , vol.17 , pp. 325-328
    • Lintas, C.1    de Matthaeis, M.C.2    Merli, F.3
  • 92
    • 84973023091 scopus 로고
    • Toxicokinetics of fluoranthene, pyrene and benz(a)anthracene in the rat
    • Lipniak, M. and Brandys, J. 1993. Toxicokinetics of fluoranthene, pyrene and benz(a)anthracene in the rat. Polycyclic Aromatic Compounds. 3: 111–119.
    • (1993) Polycyclic Aromatic Compounds , vol.3 , pp. 111-119
    • Lipniak, M.1    Brandys, J.2
  • 93
    • 44649103908 scopus 로고    scopus 로고
    • Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population
    • Li, Z., Sandau, C.D., Romanoff, L.C., Caudill, S.P., Sjodin, A., Needham, L.L. and Patterson, Jr. D.G. 2008. Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population. Environ. Res. 107 (3): 320–331.
    • (2008) Environ. Res , vol.107 , Issue.3 , pp. 320-331
    • Li, Z.1    Sandau, C.D.2    Romanoff, L.C.3    Caudill, S.P.4    Sjodin, A.5    Needham, L.L.6    Patterson, J.D.G.7
  • 94
    • 33750542715 scopus 로고    scopus 로고
    • Exposure to polycyclic aromatic hydrocarbons through consumption of edible marine species in Catalonia, Spain
    • Llobet, J.M., Falcó, G., Bocio, A. and Domingo, J.L. 2006. Exposure to polycyclic aromatic hydrocarbons through consumption of edible marine species in Catalonia, Spain. J. Food. Prot. 69 (10): 2493–2499.
    • (2006) J. Food. Prot , vol.69 , Issue.10 , pp. 2493-2499
    • Llobet, J.M.1    Falcó, G.2    Bocio, A.3    Domingo, J.L.4
  • 95
    • 4444225767 scopus 로고    scopus 로고
    • Sidestream tobacco smoke as the main predictor of exposure to polycyclic aromatic hydrocarbons
    • Lodovici, M. Akpan, V, Evangelisti, C. and Dolara, P. 2004a. Sidestream tobacco smoke as the main predictor of exposure to polycyclic aromatic hydrocarbons. J. Appl. Toxicol. 24: 277–281.
    • (2004) J. Appl. Toxicol , vol.24 , pp. 277-281
    • Lodovici, M.1    Akpan, V.2    Evangelisti, C.3    Dolara, P.4
  • 96
    • 4043058167 scopus 로고    scopus 로고
    • Benzo[a]pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH
    • Lodovici, M., Luceri, C., Guglielmi, F., Bacci, C., Akpan, V., Fonnesu, M.L., Boddi, V. and Dolara, P. 2004b. Benzo[a]pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH. Cancer Epidemiol. Biomark. Prev. 13: 1342–1348.
    • (2004) Cancer Epidemiol. Biomark. Prev , vol.13 , pp. 1342-1348
    • Lodovici, M.1    Luceri, C.2    Guglielmi, F.3    Bacci, C.4    Akpan, V.5    Fonnesu, M.L.6    Boddi, V.7    Dolara, P.8
  • 97
    • 13944266508 scopus 로고
    • Teneur en composés cancérigènes du café en grains
    • Maier, H.G. 1991. Teneur en composés cancérigènes du café en grains. Café, cacao, Thé 35 (2): 133–142.
    • (1991) Café, cacao, Thé , vol.35 , Issue.2 , pp. 133-142
    • Maier, H.G.1
  • 98
    • 17544367428 scopus 로고    scopus 로고
    • Genotoxic risk assessment in white blood cells of occupationally exposde workers before and after alteration of then poylcyclic aromatic hydrocarbon (PAH) profile on the production material
    • Marczynski, B., Preuss, R., Mensing, T., Angerer, J., Seidel, A., El Mourabit, A., Wilhelm, M. and Brüning, T. 2005. Genotoxic risk assessment in white blood cells of occupationally exposde workers before and after alteration of then poylcyclic aromatic hydrocarbon (PAH) profile on the production material. Int. Arch. Occup. Environ. Helath 78: 97–108.
    • (2005) Int. Arch. Occup. Environ. Helath , vol.78 , pp. 97-108
    • Marczynski, B.1    Preuss, R.2    Mensing, T.3    Angerer, J.4    Seidel, A.5    El Mourabit, A.6    Wilhelm, M.7    Brüning, T.8
  • 99
    • 0033024560 scopus 로고    scopus 로고
    • Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinones depurinating N7-guanine adducts
    • McCoull, K.D., Rindgen, D., Blair, I.A. and Penning, T.M. 1999. Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinones depurinating N7-guanine adducts. Chem. Res. Toxciol. 12: 237–246.
    • (1999) Chem. Res. Toxciol , vol.12 , pp. 237-246
    • McCoull, K.D.1    Rindgen, D.2    Blair, I.A.3    Penning, T.M.4
  • 100
    • 0017815884 scopus 로고
    • Some current perspectives on chemical carcinogenesis in humans and experimental animals: presidential address
    • Miller, E.C. 1978. Some current perspectives on chemical carcinogenesis in humans and experimental animals: presidential address. Cancer Res. 38: 1479–1486.
    • (1978) Cancer Res , vol.38 , pp. 1479-1486
    • Miller, E.C.1
  • 101
    • 0013887614 scopus 로고
    • Mechanism of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules
    • Miller, E.C. and Miller, J.A. 1966. Mechanism of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules. Pharmacol. Rev. 18: 805–838.
    • (1966) Pharmacol. Rev , vol.18 , pp. 805-838
    • Miller, E.C.1    Miller, J.A.2
  • 102
    • 0020507211 scopus 로고
    • Comparative kinetics of benzo[a]anthracene, chrysene, triphenylene in rats after oral administration
    • Modica, R., Fiume, M., Guaitani, A. and Bartosek, I. 1983. Comparative kinetics of benzo[a]anthracene, chrysene, triphenylene in rats after oral administration. I. Study with single compounds. Toxicol. Lett. 18: 103–109.
    • (1983) I. Study with single compounds. Toxicol. Lett , vol.18 , pp. 103-109
    • Modica, R.1    Fiume, M.2    Guaitani, A.3    Bartosek, I.4
  • 103
    • 0034053758 scopus 로고    scopus 로고
    • Quantitative determination of polycyclic aromatic hydrocarbons in barbecued meat sausages by gas chromatography coupled to mass spectrometry
    • Mottier, P., Parisod, V. and Turesky, R.J. 2000. Quantitative determination of polycyclic aromatic hydrocarbons in barbecued meat sausages by gas chromatography coupled to mass spectrometry. J. Agric. Food Chem. 48: 1160–1166.
    • (2000) J. Agric. Food Chem , vol.48 , pp. 1160-1166
    • Mottier, P.1    Parisod, V.2    Turesky, R.J.3
  • 104
    • 0027094098 scopus 로고
    • Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAH)
    • Nisbeth, I.C. and LaGoy, P.K. 1992. Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAH). Regul. Toxicol. Pharmacol. 16: 290–300.
    • (1992) Regul. Toxicol. Pharmacol , vol.16 , pp. 290-300
    • Nisbeth, I.C.1    LaGoy, P.K.2
  • 107
    • 0025357320 scopus 로고
    • Fate of PAH compounds in two soil types: Influence of volatilization, abiotic loss and biological activity
    • Park, K.S., Sims, R.C., Dupont, R.R., Doucette, W.J. and Matthews, J.E. 1990. Fate of PAH compounds in two soil types: Influence of volatilization, abiotic loss and biological activity. Environ. Toxicol. Chem. 9: 187–195
    • (1990) Environ. Toxicol. Chem , vol.9 , pp. 187-195
    • Park, K.S.1    Sims, R.C.2    Dupont, R.R.3    Doucette, W.J.4    Matthews, J.E.5
  • 108
    • 85078393759 scopus 로고    scopus 로고
    • PAH-o-quinones produce significant amounts of 8-oxo-2'-deoxyguanosine (8-oxo-dG) in salmon testis DNA
    • Meet. Soc. Toxicol., Baltimore, MD
    • Park, J., Szewczuk, L.M. and Penning, T.M. 2004. PAH-o-quinones produce significant amounts of 8-oxo-2'-deoxyguanosine (8-oxo-dG) in salmon testis DNA. Abstract # 1934. Ann. Meet. Soc. Toxicol., Baltimore, MD.
    • (2004) Ann
    • Park, J.1    Szewczuk, L.M.2    Penning, T.M.3
  • 110
    • 1242331821 scopus 로고    scopus 로고
    • GSTM1 mull genotype as a risk factor for anti-BPDE-DNA adduct formation in mononuclear white blood cells of cokeoven workers
    • Pavanello, S., Siwinska, E., Milezynska, D. and Clonfero, E. 2004. GSTM1 mull genotype as a risk factor for anti-BPDE-DNA adduct formation in mononuclear white blood cells of cokeoven workers. Mutat. Res. 558: 53–62.
    • (2004) Mutat. Res , vol.558 , pp. 53-62
    • Pavanello, S.1    Siwinska, E.2    Milezynska, D.3    Clonfero, E.4
  • 112
    • 0030065647 scopus 로고    scopus 로고
    • Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon dihydrodiols catalyzed by dihydrodiol dehydrogenase
    • Penning, T.M., Ohnishi, S.T., Ohnishi, T. and Harvey, R.G. 1996. Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon dihydrodiols catalyzed by dihydrodiol dehydrogenase. Chem. Res. Toxicol. 9: 84–92.
    • (1996) Chem. Res. Toxicol , vol.9 , pp. 84-92
    • Penning, T.M.1    Ohnishi, S.T.2    Ohnishi, T.3    Harvey, R.G.4
  • 114
    • 0033565866 scopus 로고    scopus 로고
    • Polycyclic Aromatic Hydrocarbons in the Diet
    • Phillips, D.H. 1999. Polycyclic Aromatic Hydrocarbons in the Diet. Mutat. Res., 443: 139–147.
    • (1999) Mutat. Res , vol.443 , pp. 139-147
    • Phillips, D.H.1
  • 115
    • 85078387708 scopus 로고
    • Stereoselctive activation of dibenzo[a, l]pyrene to (-)-anti(11R,12S,13S,14R) – and (+)-syn(11S,12R,13S,14R)-11, 12diol-13, 14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7
    • Ralston, S.L., Lau, H.H., Seidel, A., Luch, A. and Baird, W.M. 1995. Stereoselctive activation of dibenzo[a, l]pyrene to (-)-anti(11R,12S,13S,14R) – and (+)-syn(11S,12R,13S,14R)-11, 12diol-13, 14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7. Carcinogenesis 16: 1907–1919.
    • (1995) Carcinogenesis , vol.16 , pp. 1907-1919
    • Ralston, S.L.1    Lau, H.H.2    Seidel, A.3    Luch, A.4    Baird, W.M.5
  • 116
    • 0028268392 scopus 로고
    • The potent carcinogen dibenzo[a, l]pyrene is metabolically activated to fjord-region 11,12-diol-13, 14-epoxides in human mammary carcinoma MCF-7 cell cultures
    • Ralston, S.L., Lau, H.H., Seidel, A., Luch, A., Platt, K.L. and Baird, W.M. 1994. The potent carcinogen dibenzo[a, l]pyrene is metabolically activated to fjord-region 11,12-diol-13, 14-epoxides in human mammary carcinoma MCF-7 cell cultures. Cancer Res. 54: 887–890.
    • (1994) Cancer Res , vol.54 , pp. 887-890
    • Ralston, S.L.1    Lau, H.H.2    Seidel, A.3    Luch, A.4    Platt, K.L.5    Baird, W.M.6
  • 117
    • 0034809264 scopus 로고    scopus 로고
    • Metabolism, bioavailability, and toxicokinetics of benzo[a]pyrene [B(a)P] in F-344 rats following oral administration
    • Ramesh, A., Inyang, F. D., Hood, D.B., Archibong, A.E., Knuckles, M.E. and Nyanda, A.M. 2001. Metabolism, bioavailability, and toxicokinetics of benzo[a]pyrene [B(a)P] in F-344 rats following oral administration. Exp.Toxic. Pathol. 53: 253–270.
    • (2001) Exp.Toxic. Pathol , vol.53 , pp. 253-270
    • Ramesh, A.1    Inyang, F.D.2    Hood, D.B.3    Archibong, A.E.4    Knuckles, M.E.5    Nyanda, A.M.6
  • 118
    • 7544225521 scopus 로고    scopus 로고
    • Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons
    • Ramesh, A., Walker, S.A., Hood, D.B., Guillén, M.D., Schneider, K. and Weyand, E.H. 2004. Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons. Int. J. Toxicol. 23: 301–333.
    • (2004) Int. J. Toxicol , vol.23 , pp. 301-333
    • Ramesh, A.1    Walker, S.A.2    Hood, D.B.3    Guillén, M.D.4    Schneider, K.5    Weyand, E.H.6
  • 119
    • 34047238468 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons (PAHs) in meat products and estimated PAH intake by children and the general population in Estonia
    • Reinik, M., Tamme, T., Roasto, M., Juhkam, K., Tenno, T. and Kiis, A. 2007. Polycyclic aromatic hydrocarbons (PAHs) in meat products and estimated PAH intake by children and the general population in Estonia. Food Addit. Contam. 24 (4): 429–437.
    • (2007) Food Addit. Contam , vol.24 , Issue.4 , pp. 429-437
    • Reinik, M.1    Tamme, T.2    Roasto, M.3    Juhkam, K.4    Tenno, T.5    Kiis, A.6
  • 121
    • 34548578859 scopus 로고    scopus 로고
    • Single-laboratory validation of a GC/MS method for the determination of 27 polycyclic aromatic hydrocarbons (PAHs) in oils and fats
    • Rose, M., White, S., Macarthur, R., Petch, R.G., Holland, J. and Damant, A.P. 2007. Single-laboratory validation of a GC/MS method for the determination of 27 polycyclic aromatic hydrocarbons (PAHs) in oils and fats. Food Addit. Contam. 24 (6): 635–651.
    • (2007) Food Addit. Contam , vol.24 , Issue.6 , pp. 635-651
    • Rose, M.1    White, S.2    Macarthur, R.3    Petch, R.G.4    Holland, J.5    Damant, A.P.6
  • 122
    • 0024319372 scopus 로고
    • Comparative carcinogenicity of the PAH as a basis for acceptable exposure levels (AELs) in drinking water
    • Rugen, P.J., Stern, C.D. and Lamm, S.H. 1989. Comparative carcinogenicity of the PAH as a basis for acceptable exposure levels (AELs) in drinking water. Regul. Toxicol. Pharmacol. 9: 273.
    • (1989) Regul. Toxicol. Pharmacol , vol.9 , pp. 273
    • Rugen, P.J.1    Stern, C.D.2    Lamm, S.H.3
  • 123
    • 0345246694 scopus 로고
    • Evaluation of the induction of polycyclic aromatic hydrocarbons by cooking on two geometrically different types of barbecue
    • Saint-Aubert, B., Cooper, J.F., Astre, C., Spiliotis, J. and Joyeux, H. 1992. Evaluation of the induction of polycyclic aromatic hydrocarbons by cooking on two geometrically different types of barbecue. J. Food Compos. Anal. 5: 257–263.
    • (1992) J. Food Compos. Anal , vol.5 , pp. 257-263
    • Saint-Aubert, B.1    Cooper, J.F.2    Astre, C.3    Spiliotis, J.4    Joyeux, H.5
  • 124
    • 0037165499 scopus 로고    scopus 로고
    • Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene
    • Saunders, C.R., Ramesh, A. and Shockley, D.C. 2002. Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene. Toxicol.Lett. 129: 33–45.
    • (2002) Toxicol.Lett , vol.129 , pp. 33-45
    • Saunders, C.R.1    Ramesh, A.2    Shockley, D.C.3
  • 125
    • 0034102582 scopus 로고    scopus 로고
    • Biomonitoring of exposure to polycyclic aromatic hydrocarbons of non-occupationally exposed persons
    • Scherer, G., Frank, S., Riedel, K., Meger-Kossien, I. and Renner, T. 2000. Biomonitoring of exposure to polycyclic aromatic hydrocarbons of non-occupationally exposed persons. Cancer Epidemiol. Biomark. Prev. 9: 373–380.
    • (2000) Cancer Epidemiol. Biomark. Prev , vol.9 , pp. 373-380
    • Scherer, G.1    Frank, S.2    Riedel, K.3    Meger-Kossien, I.4    Renner, T.5
  • 127
    • 34047243800 scopus 로고    scopus 로고
    • Xenobiotix-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons
    • Shimada, T. 2006. Xenobiotix-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug Metab. Pharmacokinet. 21: 257–276.
    • (2006) Drug Metab. Pharmacokinet , vol.21 , pp. 257-276
    • Shimada, T.1
  • 128
    • 1142275258 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cyctochromes P450 1A1 and 1B1
    • Shimada, T. and Fujii-Kuriyama, Y. 2004. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cyctochromes P450 1A1 and 1B1. Cancer Sci. 95: 1–6.
    • (2004) Cancer Sci , vol.95 , pp. 1-6
    • Shimada, T.1    Fujii-Kuriyama, Y.2
  • 129
    • 0032838774 scopus 로고    scopus 로고
    • Metabolism of benzo[a]pyrene to trans-7, 8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase
    • Shimada, T., Gillam, E.M., Oda, Y., Tsumura, F., Sutter, T.R., Guengerich, F.P. and Inoue, K. 1999a. Metabolism of benzo[a]pyrene to trans-7, 8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase. Chem. Res. Toxicol. 12: 623–629.
    • (1999) Chem. Res. Toxicol , vol.12 , pp. 623-629
    • Shimada, T.1    Gillam, E.M.2    Oda, Y.3    Tsumura, F.4    Sutter, T.R.5    Guengerich, F.P.6    Inoue, K.7
  • 130
    • 0034876318 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonalla typhmurium NM 2009
    • Shimada, T., Oda, Y., Gillam, E.M.J., Guengerich, F.P. and Inoue, K. 1999b. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonalla typhmurium NM 2009. Drug Metab. Dispos. 29: 1176–1182.
    • (1999) Drug Metab. Dispos , vol.29 , pp. 1176-1182
    • Shimada, T.1    Oda, Y.2    Gillam, E.M.J.3    Guengerich, F.P.4    Inoue, K.5
  • 132
    • 22544455661 scopus 로고    scopus 로고
    • Factors affecting elimination of polycyclic aromatic hydrocarbons from smoked meat foods and liquid smoke flavorings
    • Simko, P. 2005. Factors affecting elimination of polycyclic aromatic hydrocarbons from smoked meat foods and liquid smoke flavorings. Mol. Nutr. Food Res. 49: 637–647.
    • (2005) Mol. Nutr. Food Res , vol.49 , pp. 637-647
    • Simko, P.1
  • 134
    • 0034633846 scopus 로고    scopus 로고
    • Trace determination of urinary 3-hydroxybenzo[a]pyrene by automated column-switching high-performance liquid chromatography
    • Simon, P., Lafontaine, M., Delsaut, P., Morele, Y. and Nicot, T. 2000. Trace determination of urinary 3-hydroxybenzo[a]pyrene by automated column-switching high-performance liquid chromatography. J. Chromatogr. B 748: 337–348.
    • (2000) J. Chromatogr. B , vol.748 , pp. 337-348
    • Simon, P.1    Lafontaine, M.2    Delsaut, P.3    Morele, Y.4    Nicot, T.5
  • 135
    • 0018757754 scopus 로고
    • Potent tumor initiating activity of the 3,4-dihydrodiol-7, 12-dimethylbenz[a]anthracene in mouse skin
    • Slaga, T.J., Gleason, G.L., DiGiovanni, J., Sukumaran, K.B. and Harvey, R.G. 1979. Potent tumor initiating activity of the 3,4-dihydrodiol-7, 12-dimethylbenz[a]anthracene in mouse skin. Cancer Res. 39: 1934–1936.
    • (1979) Cancer Res , vol.39 , pp. 1934-1936
    • Slaga, T.J.1    Gleason, G.L.2    DiGiovanni, J.3    Sukumaran, K.B.4    Harvey, R.G.5
  • 136
    • 84985274510 scopus 로고
    • Determination and distribution of polycyclic aromatic hydrocarbons in native vegetable oils, smoked fish products, mussels and oysters, and bream from the river Elbe
    • Speer, K., Steeg, E., Horstmann, P., Kühn, T. and Montag, A. 1990. Determination and distribution of polycyclic aromatic hydrocarbons in native vegetable oils, smoked fish products, mussels and oysters, and bream from the river Elbe. J. High Res. Chrom., 13: 104–111.
    • (1990) J. High Res. Chrom , vol.13 , pp. 104-111
    • Speer, K.1    Steeg, E.2    Horstmann, P.3    Kühn, T.4    Montag, A.5
  • 137
    • 0028307770 scopus 로고
    • Roles of electrophilic sulphuric acid ester metabolites in mutagenesis and carcinogenesis by som polycyclic aromatic hydrocarbons
    • Surh, Y.-J. and Miller, J.A. 1994. Roles of electrophilic sulphuric acid ester metabolites in mutagenesis and carcinogenesis by som polycyclic aromatic hydrocarbons. Chem.-Biol. Interact. 92: 351–362.
    • (1994) Chem.-Biol. Interact , vol.92 , pp. 351-362
    • Surh, Y.-J.1    Miller, J.A.2
  • 139
    • 0033012105 scopus 로고    scopus 로고
    • Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures
    • Till, M., Riebniger, D., Schmitz, H.-J. and Schrenk, D. 1999. Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures. Chem.-Biol. Interact. 29: 135–150.
    • (1999) Chem.-Biol. Interact , vol.29 , pp. 135-150
    • Till, M.1    Riebniger, D.2    Schmitz, H.-J.3    Schrenk, D.4
  • 140
    • 0022355846 scopus 로고
    • Fluid chromatographic determination of benzo(a)pyrene in total particulate matter of cigarette smoke
    • Tomkins, B. A., Jenkins, R. A., Griest, W. H., Reagan, R. R. and Holladay, S. K. 1985. Fluid chromatographic determination of benzo(a)pyrene in total particulate matter of cigarette smoke. J. AOAC 68: 935–940
    • (1985) J. AOAC , vol.68 , pp. 935-940
    • Tomkins, B.A.1    Jenkins, R.A.2    Griest, W.H.3    Reagan, R.R.4    Holladay, S.K.5
  • 142
    • 0001372176 scopus 로고
    • Guidance for health risk from exposure to chemical mixtures
    • US EPA (United Sates, Environmental Protection Agency). 1986. Guidance for health risk from exposure to chemical mixtures. U.S. Environmental Protection Agency, Fed Reg, 51, 34014.
    • (1986) U.S. Environmental Protection Agency, Fed Reg , vol.51 , pp. 34014
  • 143
    • 0013230564 scopus 로고    scopus 로고
    • Esposizione personale a benzo[a]pirene in aree urbane e rurali (dati preliminari) [Personal exposure to benzo[a]pyrene in urban and rural areas (preliminary data)]
    • Aprea, C., Sciarra, G., Fiorentino, M.L., Minoia, C., ed.),, Morgan Edizioni Tecniche, Milano, Italy
    • Valerio, F., Ciccarelli, F. and Roggi, C. 1996. Esposizione personale a benzo[a]pirene in aree urbane e rurali (dati preliminari) [Personal exposure to benzo[a]pyrene in urban and rural areas (preliminary data)]. In: I valori di riferimento e i valori limite nella prevenzione ambientale e occupazionale (Aprea, C., Sciarra, G., Fiorentino, M.L. and Minoia, C., ed.), Morgan Edizioni Tecniche, Milano, Italy, pp. 337–341.
    • (1996) I valori di riferimento e i valori limite nella prevenzione ambientale e occupazionale , pp. 337-341
    • Valerio, F.1    Ciccarelli, F.2    Roggi, C.3
  • 145
    • 0027973153 scopus 로고
    • Formation of aromatic DNA adducts in white blood cells in relation to urinary excretion of 1-hydroxypyrene during consumption of grilled meat
    • van Maanen, J.M., Moonen, E.J., Maas, L.M., Kleinjans, J.C. and van Schooten, F.J. 1994. Formation of aromatic DNA adducts in white blood cells in relation to urinary excretion of 1-hydroxypyrene during consumption of grilled meat. Carcinogenesis 15: 2263–2268.
    • (1994) Carcinogenesis , vol.15 , pp. 2263-2268
    • van Maanen, J.M.1    Moonen, E.J.2    Maas, L.M.3    Kleinjans, J.C.4    van Schooten, F.J.5
  • 146
    • 0030685054 scopus 로고    scopus 로고
    • Determination of polycyclic aromatic hydrocarbons (PAH) and their metabolites in blood, feces and urine of rats orally exposed to PAH contaminated soils
    • van Schooten, F.J., Moonen, E.J.C., van der Wal, L., Levels, P. and Kleinjans, J.C.S. 1997. Determination of polycyclic aromatic hydrocarbons (PAH) and their metabolites in blood, feces and urine of rats orally exposed to PAH contaminated soils. Arch. Environ. Contam. Toxicol. 33: 317–322.
    • (1997) Arch. Environ. Contam. Toxicol , vol.33 , pp. 317-322
    • van Schooten, F.J.1    Moonen, E.J.C.2    van der Wal, L.3    Levels, P.4    Kleinjans, J.C.S.5
  • 147
    • 34447295347 scopus 로고    scopus 로고
    • Determination of PAH profile by GC-MS/MS in salmon by processed by four cold-smoking techniques
    • Varlet, V., Serot, T., Monteau, F., Le Bizec, B. and Prost, C. 2007. Determination of PAH profile by GC-MS/MS in salmon by processed by four cold-smoking techniques. Food Addit. Contam. 24 (7): 744–757.
    • (2007) Food Addit. Contam , vol.24 , Issue.7 , pp. 744-757
    • Varlet, V.1    Serot, T.2    Monteau, F.3    Le Bizec, B.4    Prost, C.5
  • 148
    • 34247228548 scopus 로고    scopus 로고
    • Innovative method for determination of 19 polycyclic aromatic hydrocarbons in food and oil samples using gas chromatography coupled to tandem mass spectrometry based on an isotope dilution approach
    • Veyrand, B., Brosseaud, A., Sarcher, L., Varlet, V., Monteau, F., Marchand, P., Andre, F. and Le Bizec, B. 2007. Innovative method for determination of 19 polycyclic aromatic hydrocarbons in food and oil samples using gas chromatography coupled to tandem mass spectrometry based on an isotope dilution approach. J. Chromatogr. A: 1149: 333–344.
    • (2007) J. Chromatogr. A: , vol.1149 , pp. 333-344
    • Veyrand, B.1    Brosseaud, A.2    Sarcher, L.3    Varlet, V.4    Monteau, F.5    Marchand, P.6    Andre, F.7    Le Bizec, B.8
  • 149
    • 0037026984 scopus 로고    scopus 로고
    • Is 1-hydroxypyrene a reliable bioindicator of measured dietary polycyclic aromatic hydrocarbon under normal conditions?
    • Viau, C., Diakite, A., Ruzgyte, A., Tuchweber, B., Blasi, C., Bouchard, M. and Vyskocil, A. 2002. Is 1-hydroxypyrene a reliable bioindicator of measured dietary polycyclic aromatic hydrocarbon under normal conditions? J. Chromatogr. B 778: 165–177.
    • (2002) J. Chromatogr. B , vol.778 , pp. 165-177
    • Viau, C.1    Diakite, A.2    Ruzgyte, A.3    Tuchweber, B.4    Blasi, C.5    Bouchard, M.6    Vyskocil, A.7
  • 150
    • 33646493007 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons in fresh and cold-smoked Atlantic salmon fillets
    • Visciano, P., Perugini, M., Amorena, M. and Ianieri, A. 2006. Polycyclic aromatic hydrocarbons in fresh and cold-smoked Atlantic salmon fillets. J. Food Prot. 69: 1134–1138.
    • (2006) J. Food Prot , vol.69 , pp. 1134-1138
    • Visciano, P.1    Perugini, M.2    Amorena, M.3    Ianieri, A.4
  • 153
    • 33745095421 scopus 로고    scopus 로고
    • Selected Non-heterocyclic Polycyclic Aromatic Hydrocarbons
    • International Programme on Chemical Safety, World Health Organization, Geneva
    • WHO/IPCS (World Health Organization/International Programme on Chemical Safety). 1998. Selected Non-heterocyclic Polycyclic Aromatic Hydrocarbons. Environmental Health Criteria 202. International Programme on Chemical Safety, World Health Organization, Geneva.
    • (1998) Environmental Health Criteria 202
  • 154
    • 0022437728 scopus 로고
    • Tobacco Smoking
    • International Agency for Research on Cancer, Lyon
    • WHO/IARC (World Health Organization/The International Agency for Research on Cancer) 1986. Tobacco Smoking. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 38. International Agency for Research on Cancer, Lyon.
    • (1986) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol , vol.38
  • 155
    • 85078368169 scopus 로고
    • Lyon, International Agency for Research on Cancer, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man
    • WHO/IARC (World Health Organization/The International Agency for Research on Cancer). 1989. Occupational exposures in petroleum refining: Crude oil and major petroleum fuels. Lyon, International Agency for Research on Cancer. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man, Volume 45.
    • (1989) Occupational exposures in petroleum refining: Crude oil and major petroleum fuels , vol.45
  • 156
    • 20444412643 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review
    • Xue, W. and Warschawsky, D. 2005. Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review. Toxicol. Appl. Pharmacol. 206: 73–93.
    • (2005) Toxicol. Appl. Pharmacol , vol.206 , pp. 73-93
    • Xue, W.1    Warschawsky, D.2
  • 157
    • 0003330967 scopus 로고
    • The uptake and distribution of benzo[a]pyrene in rat after continuous oral administration
    • Yamazaki, H. and Kakiuchi, Y. 1989. The uptake and distribution of benzo[a]pyrene in rat after continuous oral administration. Toxicol. Environ. Chem. 24 (1/2): 95–104.
    • (1989) Toxicol. Environ. Chem , vol.24 , Issue.1-2 , pp. 95-104
    • Yamazaki, H.1    Kakiuchi, Y.2
  • 158
    • 0023866757 scopus 로고
    • Stereo selectivity of cytochrome P450 isozymes and epoxide hydrolase in the metabolism of polycyclic aromatic hyrocarbons
    • Yang, S.K. 1988. Stereo selectivity of cytochrome P450 isozymes and epoxide hydrolase in the metabolism of polycyclic aromatic hyrocarbons. Biochem. Pharmacol. 37: 61–70.
    • (1988) Biochem. Pharmacol , vol.37 , pp. 61-70
    • Yang, S.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.