4-hydroxy-2(E)-nonenal metabolism differs in Apc +/+ Cells and in Apc Min/+ cells: It may explain colon cancer promotion by heme iron

Chemical Research in Toxicology

Volumn 24, Issue 11, 2011, Pages 1984-1993

  Baradat, Maryse ^a   Jouanin, Isabelle ^a   Dalleau, Sabine ^a   Taché, Sylviane ^a   Gieules, Mathilde ^a   Debrauwer, Laurent ^a   Canlet, Cécile ^a   Huc, Laurence ^a   Dupuy, Jacques ^a   Pierre, Fabrice H F ^a   Guéraud, Françoise ^a  

^a TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONANAL; 4 HYDROXYNONANOIC ACID; 4 HYDROXYNONENAL; ALDEHYDE DEHYDROGENASE; APC PROTEIN; CARRIER PROTEIN; CYSTEINE; CYSTEINE TRANSPORTER XCT PROTEIN; GLUTATHIONE TRANSFERASE A4; HEME; MESSENGER RNA; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; COLON; COLON CARCINOGENESIS; COLORECTAL CANCER; CONCENTRATION (PARAMETERS); CONJUGATION; CYTOTOXICITY; EPITHELIUM CELL; GENE MUTATION; INCUBATION TIME; ISOTOPE LABELING; LIPID OXIDATION; METABOLISM; METABOLITE; MOUSE; NONHUMAN; REDUCTION KINETICS; WILD TYPE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ALDEHYDE DEHYDROGENASE; ALDEHYDES; ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLON; COLORECTAL NEOPLASMS; DNA DAMAGE; EPITHELIAL CELLS; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEME; HUMANS; IRON; ISOTOPE LABELING; MASS SPECTROMETRY; MICE; MUTATION; OXIDATION-REDUCTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 81755175675     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx2003036     Document Type: Article

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