Dietary heme-mediated PPARα activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  IJssennagger, Noortje ^a,b   de Wit, Nicole ^a,b   Müller, Michael ^a,b   van der Meer, Roelof ^a,b  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; HEME; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR FRA 1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTOME; UNCLASSIFIED DRUG; VANIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; COLON MUCOSA; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOTYPE; HYPERPLASIA; KNOCKOUT MOUSE; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN FUNCTION; UPREGULATION; WILD TYPE;

ANIMAL FEED; ANIMALS; ANTIOXIDANTS; CELL PROLIFERATION; COLON; COLONIC NEOPLASMS; HEME; IMMUNOHISTOCHEMISTRY; LIPID METABOLISM; MALE; MEAT; MICE; MICE, KNOCKOUT; MUCOUS MEMBRANE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PPAR ALPHA; REACTIVE OXYGEN SPECIES; RISK;

EID: 84865050645     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043260     Document Type: Article

References (38)

1. Jemal A, Siegel R, Xu J, Ward E, ((2010)) Cancer statistics, 2010. CA: a cancer journal for clinicians 60:: 277--300.
2. Bastide NM, Pierre FH, Corpet DE, ((2011)) Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved. Cancer prevention research 4:: 177--184.
3. World Cancer Research Fund (2007) Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective. Washington, DC: American Institute for Cancer Research.
4. Sesink AL, Termont DS, Kleibeuker JH, Van der Meer R, ((1999)) Red meat and colon cancer: the cytotoxic and hyperproliferative effects of dietary heme. Cancer Res 59:: 5704--5709.
5. IJssennagger N, Rijnierse A, de Wit N, Jonker-Termont D, Dekker J, et al. ((2011)) Dietary haem stimulates epithelial cell turnover by downregulating feedback inhibitors of proliferation in murine colon. Gut 61:: 1041--9.
6. Kinzler KW, Vogelstein B, ((1996)) Lessons from hereditary colorectal cancer. Cell 87:: 159--170.
7. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, et al. ((1994)) Intake of fat, meat, and fiber in relation to risk of colon cancer in men. Cancer Res 54:: 2390--2397.
8. Larsson SC, Rafter J, Holmberg L, Bergkvist L, Wolk A, ((2005)) Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish Mammography Cohort. Int J Cancer 113:: 829--834.
9. Abdelmegeed MA, Moon KH, Hardwick JP, Gonzalez FJ, Song BJ, ((2009)) Role of peroxisome proliferator-activated receptor-alpha in fasting-mediated oxidative stress. Free Radic Biol Med 47:: 767--778.
10. Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, et al. ((1995)) Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15:: 3012--3022.
11. de Vogel J, Jonker-Termont DS, van Lieshout EM, Katan MB, van der Meer R, ((2005)) Green vegetables, red meat and colon cancer: chlorophyll prevents the cytotoxic and hyperproliferative effects of haem in rat colon. Carcinogenesis 26:: 387--393.
12. Ohkawa H, Ohishi N, Yagi K, ((1979)) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical biochemistry 95:: 351--358.
13. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. ((2004)) Bioconductor: open software development for computational biology and bioinformatics. Genome biology 5:: R80.
14. Lin K, Kools H, de Groot PJ, Gavai AK, Basnet RK, et al. ((2011)) MADMAX- Management and analysis database for multiple ~omics experiments. J Integr Bioinform 8:: 160.
15. Bolstad BM, Irizarry RA, Astrand M, Speed TP, ((2003)) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19:: 185--193.
16. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, et al. ((2003)) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31:: e15.
17. Dai M, Wang P, Boyd AD, Kostov G, Athey B, et al. ((2005)) Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 33:: e175.
18. Bunger M, van den Bosch HM, van der Meijde J, Kersten S, Hooiveld GJ, et al. ((2007)) Genome-wide analysis of PPARalpha activation in murine small intestine. Physiological genomics 30:: 192--204.
19. Venugopal R, Jaiswal AK, ((1996)) Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc Natl Acad Sci U S A 93:: 14960--14965.
20. Yang HP, Magilnick N, Lee C, Kalmaz D, Ou XP, et al. ((2005)) Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappa B and AP-1. Molecular and Cellular Biology 25:: 5933--5946.
21. de Vogel J, van-Eck WB, Sesink AL, Jonker-Termont DS, Kleibeuker J, et al. ((2008)) Dietary heme injures surface epithelium resulting in hyperproliferation, inhibition of apoptosis and crypt hyperplasia in rat colon. Carcinogenesis 29:: 398--403.
22. Harada T, Koyama I, Kasahara T, Alpers DH, Komoda T, ((2003)) Heat shock induces intestinal-type alkaline phosphatase in rat IEC-18 cells. American journal of physiology Gastrointestinal and liver physiology 284:: G255--262.
23. Berruyer C, Martin FM, Castellano R, Macone A, Malergue F, et al. ((2004)) Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress. Mol Cell Biol 24:: 7214--7224.
24. Rakhshandehroo M, Knoch B, Muller M, Kersten S (2010) Peroxisome proliferator-activated receptor alpha target genes. PPAR Res 2010.
25. Andrews GK, ((2000)) Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem Pharmacol 59:: 95--104.
26. Anton PM, Theodorou V, Roy S, Fioramonti J, Bueno L, ((2002)) Pathways involved in mild gastrointestinal inflammation induced by a low level exposure to a food contaminant. Digestive diseases and sciences 47:: 1308--1315.
27. Pialoux V, Mounier R, Brown AD, Steinback CD, Rawling JM, et al. ((2009)) Relationship between oxidative stress and HIF-1 alpha mRNA during sustained hypoxia in humans. Free Radic Biol Med 46:: 321--326.
28. Lee SJ, Kim CE, Yun MR, Seo KW, Park HM, et al. ((2010)) 4-Hydroxynonenal enhances MMP-9 production in murine macrophages via 5-lipoxygenase-mediated activation of ERK and p38 MAPK. Toxicology and Applied Pharmacology 242:: 191--198.
29. Zoete V, Grosdidier A, Michielin O, ((2007)) Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators. Biochim Biophys Acta 1771:: 915--925.
30. Patsouris D, Reddy JK, Muller M, Kersten S, ((2006)) Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression. Endocrinology 147:: 1508--1516.
31. Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, et al. ((2002)) Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. J Biol Chem 277:: 26089--26097.
32. Pierre F, Tache S, Petit CR, Van der Meer R, Corpet DE, ((2003)) Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats. Carcinogenesis 24:: 1683--1690.
33. Pouyet L, Roisin-Bouffay C, Clement A, Millet V, Garcia S, et al. ((2010)) Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model. Inflamm Bowel Dis 16:: 96--104.
34. Nguyen T, Nioi P, Pickett CB, ((2009)) The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284:: 13291--13295.
35. Thompson J, Ory J, Reese-Wagoner A, Banaszak L, ((1999)) The liver fatty acid binding protein-comparison of cavity properties of intracellular lipid-binding proteins. Mol Cell Biochem 192:: 9--16.
36. Reddy SP, Mossman BT, ((2002)) Role and regulation of activator protein-1 in toxicant-induced responses of the lung. Am J Physiol Lung Cell Mol Physiol 283:: L1161--1178.
37. Wang G, Gong Y, Anderson J, Sun D, Minuk G, et al. ((2005)) Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells. Hepatology 42:: 871--879.
38. Yamamoto T, Noiri E, Ono Y, Doi K, Negishi K, et al. ((2007)) Renal L-type fatty acid-binding protein in acute ischemic injury. J Am Soc Nephrol 18:: 2894--2902.