Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

Genome Research

Volumn 22, Issue 2, 2012, Pages 299-306

  Castellarin, Mauro ^a,b   Warren, René L ^a   Freeman, J Douglas ^a   Dreolini, Lisa ^a   Krzywinski, Martin ^a   Strauss, Jaclyn ^c   Barnes, Rebecca ^a   Watson, Peter ^a   Allen Vercoe, Emma ^c   Moore, Richard A ^a,b   Holt, Robert A ^a,b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b SIMON FRASER UNIVERSITY   (Canada)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COLORECTAL CARCINOMA; DISEASE ASSOCIATION; FECES MICROFLORA; FUSOBACTERIUM INFECTION; FUSOBACTERIUM NUCLEATUM; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RNA SEQUENCE;

CELL LINE, TUMOR; CLUSTER ANALYSIS; COLORECTAL NEOPLASMS; FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NUCLEATUM; GENOME, BACTERIAL; HUMANS; INTESTINE, LARGE; METAGENOME; PHYLOGENY;

FUSOBACTERIA; FUSOBACTERIUM; FUSOBACTERIUM NUCLEATUM;

EID: 84856534859     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.126516.111     Document Type: Article

References (39)

1. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, MillerW, Lipman DJ. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 3389-3402. (Pubitemid 27359211)
2. Ben-Dov E, Shapiro OH, Siboni N, Kushmaro A. 2006. Advantage of using inosine at the 3′ termini of 16S rRNA gene universal primers for the study of microbial diversity. Appl Environ Microbiol 72: 6902-6906. (Pubitemid 44748399)
3. Bolstad A, Jensen H, Bakken V. 1996. Taxonomy, biology, and periodontal aspects of Fusobacterium nucleatum. Clin Microbiol Rev 9: 55-71. (Pubitemid 26035539)
4. Ewing B, Hillier L, Wendl MC, Green P. 1998. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res 8:175-185. (Pubitemid 28177229)
5. Feng H, Shuda M, Chang Y, Moore PS. 2008. Clonal integration of a polyomavirus inhumanMerkel cell carcinoma. Science 319: 1096-1100. (Pubitemid 351300792)
6. Flicek P, Amode MR, Barrell D, Beal K, Brent S, Chen Y, Clapham P, Coates G, Fairley S, Fitzgerald S, et al. 2011. Ensembl 2011. Nucleic Acids Res 39:D800-D806.
7. Forbes N. 2010. Engineering the perfect (bacterial) cancer therapy. Nat Rev Cancer 10: 784-793.
8. Han YW, Shi W, Huang GT, Kinder Haake S, Park NH, Kuramitsu H, Genco RJ. 2000. Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells. Infect Immun 68: 3140-3146. (Pubitemid 30340401)
9. Han XY, Weinberg JS, Prabhu SS, Hassenbusch SJ, Fuller GN, Tarrand JJ, Kontoyiannis DP. 2003. Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis. J Neurosurg 99: 693-700. (Pubitemid 37159047)
10. Kai A, Cooke F, Antoun N, Siddharthan C, Sule O. 2008. A rare presentation of ventriculitis and brain abscess caused by Fusobacterium nucleatum. J Med Microbiol 57: 668-671. (Pubitemid 351632918)
11. Kim M-K, Kim H-K, Kim B-O, Yoo SY, Seong J-H, Kim D-K, Lee SE, Choe S-J, Park J-C, Min B-M, et al. 2004. Multiplex PCR using conserved and species-specific 16S rDNA primers for simultaneous detection of Fusobacterium nucleatum and Actinobacillus actinomycetemcomitans. J Microbiol Biotechnol 14: 110-115. (Pubitemid 38325064)
12. Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, Ojesina AI, Jung J, Bass AJ, Tabernero J, et al. 2012. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res (this issue). doi: 10.1101/gr.126573.111.
13. Krisanaprakornkit S, Kimball JR, Weinberg A, Darveau RP, Bainbridge BW, Dale BA. 2000. Inducible expression of human β-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: Multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. Infect Immun 68: 2907-2915. (Pubitemid 30253871)
14. Li H, Durbin R. 2010. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics 26: 589-595.
15. Marchesi JR, Dutilh BE, Hall N, Peters WH, Roelofs R, Boleij A, Tjalsma H. 2011. Towards the Human Colorectal Cancer Microbiome. PLOS ONE 6:e20447. doi: 10.1371/journal.pone.0020447.
16. Marshall B, Warren J. 1984. Unidentified curved bacilli in the stomach of patients with gastritis and peptic-ulceration. Lancet 1: 1311-1315.
17. McLean MH, Murray GI, Stewart KN, Norrie G, Mayer C, Hold GL, Thomson J, Fyfe N, Hope M, Mowat NA, et al. 2011. The inflammatory microenvironment in colorectal neoplasia. PLoS ONE 6: e15366. doi: 10.1371/journal.pone.0015366.
18. Moore RA,Warren RL, Freeman JD, Gustavsen JA, Chénard C, Friedman JM, Suttle CA, Zhao Y, Holt RA. 2011. The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissue. PLoS ONE 6: e19838. doi: 10.1371/journal.pone.0019838.
19. Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, Paul JE, Boyle M, Woolcock BW, Kuchenbauer F, et al. 2010. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 42: 181-185.
20. Nelson KE, Weinstock GM, Highlander SK, Worley KC, Creasy HH, Wortman JR, Rusch DB, Mitreva M, Sodergren E, et al. 2010. a catalog of reference genomes from the human microbiome. Science 328:994-999.
21. Parkin D. 2006. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 118: 3030-3044.
22. Peyret-Lacombe A, Brunel G,Watts M, Charveron M, Duplan H. 2009. TLR2 sensing of F. nucleatum and S. sanguinis distinctly triggered gingival innate response. Cytokine 46: 201-210.
23. Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, Nielsen T, Pons N, Levenez F, Yamada T, et al. 2010. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464: 59-65.
24. Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, Delaney A, Gelmon K, Guliany R, Senz J, et al. 2009. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461: 809-813.
25. Signat B, Roques C, Poulet P, Duffaut D. 2011. Role of Fusobacterium nucleatumin periodontal health and disease. Curr Issues Mol Biol 13: 25-35.
26. Sokal R, Michener C. 1958. A statistical method for evaluating systematic relationships. Univ Kans Sci Bull 28: 1409-1438.
27. Strauss J, White A, Ambrose C, McDonald J, Allen-Vercoe E. 2008. Phenotypic and genotypic analyses of clinical Fusobacterium nucleatum and Fusobacterium periodonticum isolates from the human gut. Anaerobe 14: 301-309.
28. Strauss J, Kaplan GG, Beck PL, Rioux K, Panaccione R, DeVinney R, Lynch T, Allen-Vercoe E. 2011. Invasive potential of gut mucosa-derived Fusobacterium nucleatum positively correlates with IBD status of the host. Inflamm Bowel Dis 17: 1971-1978.
29. Swidsinski A, Dörffel Y, Loening-Baucke V, Theissig F, Rückert JC, Ismail M, Rau WA, Gaschler D, Weizenegger M, Kühn S, et al. 2011. Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum. Gut 60: 34-40.
30. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AM, Bos JL. 1988. Genetic alterations during colorectal-tumour development. N Engl JMed 319: 525-532.
31. Warren RL, Sutton GG, Jones SJ, Holt RA. 2007. Assembling millions of short DNA sequences using SSAKE. Bioinformatics 23: 500-501. (Pubitemid 46323134)
32. Watson PH. 2010. Canadian Tumour Repository Network. Biopreserv Biobank 8: 181-185.
33. Weber G, Shendure J, Tanenbaum DM, Church GM, Meyerson M. 2002. Identification of foreign gene sequences by transcript filtering against the human genome. Nat Genet 30: 141-142.
34. Weeks DF, Katz DS, Saxon P, Kubal WS. 2010 Lemierre syndrome: report of five new cases and literature review. Emerg Radiol 17: 323-328.
35. Weiss EL, Shaniztki B, Dotan M, Ganeshkumar N, Kolenbrander PE, Metzger Z. 2000. Attachment of Fusobacterium nucleatum PK1594 to mammalian cells and its coaggregation with periodontopathogenic bacteria are mediated by the same galactose-binding adhesin. Oral Microbiol Immunol 15: 371-377.
36. Wilson G, Flibotte S, Chopra V, Melnyk B, Honer W, Holt R. 2006. DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling. Hum Mol Genet 15:743-749. (Pubitemid 43264699)
37. World Health Organization. 2011. Fact sheet no. 297. World Health Organization, Geneva, Switzerland. http://www.who.int/mediacentre/factsheets/ fs297/en/.
38. Wu S, Rhee KJ, Albesiano E, Rabizadeh S,Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, et al. 2009. A human colonic commensal promotes colon tumourigenesis via activation of T helper type 17 T cell responses. Nat Med 15: 1016-1022.
39. Ximenez-Fyvie LA, Haffajee AD, Socransky SS. 2000. Comparison of the microbiota of supra- and subgingival plaque in health and periodontitis. J Clin Periodontol 27: 648-657.