Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 594, Issue 1-2, 2006, Pages 162-171

  Glei, Michael ^a   Klenow, Stefanie ^a   Sauer, Julia ^a   Wegewitz, Uta ^a   Richter, Konrad ^a   Pool Zobel, Beatrice L ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Colon cells; H2O2; Hemin; Hemoglobin; HT29 clone 19A; Single cell microgelelectrophoresis (comet assay)

Indexed keywords

DIMETHYL SULFOXIDE; HEMIN; HEMOGLOBIN; HYDROGEN PEROXIDE;

ADULT; AGED; ARTICLE; CELL COUNT; CELL GROWTH; CELL MEMBRANE; CELL METABOLISM; CELL STRAIN HT29; CLINICAL ARTICLE; COLON TUMOR; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG MECHANISM; GENOTOXICITY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL;

AGED; CELLS, CULTURED; CLONE CELLS; COLON; DIMETHYL SULFOXIDE; DNA DAMAGE; FREE RADICAL SCAVENGERS; GROWTH INHIBITORS; HEMIN; HEMOGLOBINS; HT29 CELLS; HUMANS; HYDROGEN PEROXIDE; IRON; MALE; MUTAGENS; MUTATION;

EID: 31644437054     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.08.006     Document Type: Article

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