Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon

Nutrition and Cancer

Volumn 62, Issue 5, 2010, Pages 567-573

  Pierre, Fabrice H F ^a   Santarelli, Raphaëlle L ^a   Allam, Ossama ^a   Taché, Sylviane ^a   Naud, Nathalie ^a   Guéraud, Françoise ^b   Corpet, Denis E ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; BIOLOGICAL MARKER; FREE NITROSYL HEME; HEME DERIVATIVE; HEMIN; HEMOGLOBIN; MUCIN; MYOGLOBIN; NITRITE; PHOSPHATE; SODIUM CHLORIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON CARCINOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; DISEASE ASSOCIATION; FECES; FEMALE; FREEZE DRYING; LIPID PEROXIDATION; NONHUMAN; RAT; RED MEAT; URINARY TRACT; ANIMAL; COLONIC NEOPLASMS; FISCHER 344 RAT; MEAT; PRECANCEROUS CONDITIONS; SWINE; TOXICITY;

RATTUS; RODENTIA;

ANIMALS; AZOXYMETHANE; COLONIC NEOPLASMS; FEMALE; FREEZE DRYING; HEMIN; LIPID PEROXIDATION; MEAT PRODUCTS; MUCINS; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED F344; SWINE;

EID: 77954024754     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635580903532408     Document Type: Article

References (36)

1. Cummings JH and Bingham SA: Fortnightly review-diet and the prevention of cancer. Brit Med J 317, 1636-1640, 1998.
2. Sandhu MS,White IR, and Mcpherson K: Systematic reviewof the prospective cohort studies on meat consumption and colorectal cancer risk: a meta-analytical approach. Cancer Epidemiol Biomarkers Prev 10, 439-446, 2001
3. Norat T, Lukanova A, Ferrari P, and Riboli E: Meat consumption and colorectal cancer risk: dose-responsemeta-analysis of epidemiological studies. Int J Cancer 98, 241-256, 2002.
4. Larsson SC and Wolk A: Meat consumption and risk of colorectal cancer: a meta-analysis of prospective studies. Int J Cancer 119, 2657-2664, 2006. (Pubitemid 44691322)
5. Santarelli RL, Pierre F, and Corpet DE: Processed meat and colorectal cancer: a review of epidemiologic and experimental evidence. Nutr Cancer 60, 131-144, 2008.
6. Demeyer D, Honikel K, and De Smet S: The World Cancer Research Fund report 2007: a challenge for the meat processing industry. Meat Sci 80, 953-959, 2008.
7. Bingham SA, Pignatelli B, Pollock JRA, Ellul A, Malaveille C, et al.: Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis 17, 515-523, 1996. (Pubitemid 26085332)
8. Cross AJ, Pollock JRA, and Bingham SA: Haem, not protein or inorganic iron, is responsible for endogenous intestinal n-nitrosation arising from red meat. Cancer Res 63, 2358-2360, 2003.
9. Lunn JC, Kuhnle G,Mai V, Frankenfeld C, Shuker DE, et al.: The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tract. Carcinogenesis 28, 685-690, 2007.
10. Parnaud G, Pignatelli B, Peiffer G, Tache S, and Corpet DE: Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats. Nutr Cancer 38, 74-80, 2000.
11. Sugimura T, Wakabayashi K, Nakagama H, and Nagao M: Heterocyclic amines: mutagens/carcinogens produced during cooking of meat and fish. Cancer Sci 95, 290-299, 2004. (Pubitemid 38519467)
12. Sinha R, Rothman N, Brown ED, Mark SD, Hoover RN, et al.: Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome p4501a2 activity in humans. Cancer Res 54, 6154-6159, 1994.
13. Stavric B: Biological significance of trace levels of mutagenic heterocyclic aromatic amines in human diet: a critical review. Food Chem Toxicol 32, 977-994, 1994.
14. Sesink ALA, Termont DSML, Kleibeuker JH, and Vandermeer R: Redmeat and colon cancer: the cytotoxic and hyperproliferative effects of dietary heme. Cancer Res 59, 5704-5709, 1999.
15. Pierre F, Freeman A, Tache S, Van Der Meer R, and Corpet DE: Beef meat and blood sausage promote the formation of azoxymethane-induced mucindepleted foci and aberrant crypt foci in rat colons. J Nutr 134, 2711-2716, 2004.
16. Pierre F, Tache S, Petit CR, Van Der Meer R, and Corpet DE: Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats. Carcinogenesis 24, 1683-1690, 2003.
17. Pierre F, Santarelli R, Tache S, Gueraud F, and Corpet DE: Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium. Br J Nutr 99, 1000-1006, 2008.
18. Parnaud G, Peiffer G, Tache S, and Corpet DE: Effect of meat (beef, chicken, and bacon) on rat colon carcinogenesis. Nutr Cancer 32, 165-173, 1998.
19. KarkareMR, Clark TD, and Glauert HP: Effect of dietary calcium on colon carcinogenesis induced by a single injection of 1,2-dimethylhydrazine in rats. J Nutr 121, 568-577, 1991.
20. American Institute of Nutrition: Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies. J Nutr 107, 1340-1348, 1977.
21. Bird RP: Observation and quantification of aberrant crypts in murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 37, 147-151, 1987.
22. Femia AP, Dolara P, Giannini A, Salvadori M, Biggeri A, et al.: Frequent mutation of Apc gene in rat colon tumors and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 67, 445-449, 2007.
23. CaderniG, Femia AP, Giannini A, Favuzza A, Luceri C, et al.: Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res 63, 2388-2392, 2003.
24. Ohkawa H, Ohishi N, and Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95, 351-358, 1979.
25. VanDen Berg JW,Koole-Lesuis R, Edixhoven-Bosdijk A, and BrouwersN: Automating the quantification of heme in feces. Clin Chem 34, 2125-2126. 1988.
26. Bonneson C, Eggleston IM, and Hayes JD: Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 61, 6120-6130, 2001.
27. Gueraud F, Peiro G, Bernard H, Alary J, Creminon C, et al.: Enzyme immunoassay for a urinary metabolite of 4-hydroxynonenal as a marker of lipid peroxidation. Free Radic Biol Med 40, 54-62, 2006.
28. Femia AP, Dolara P, and Caderni G: Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis. Carcinogenesis 25, 277-281, 2004.
29. Pegg RB and Shahidi F: Nitrite Curing of Meat: The N-Nitrosamine Problem and Nitrite Alternatives: The Color of Meat. Trumbull, CT: Food & Nutrition Press, Inc., 2000, pp. 23-66.
30. Shahidi F and Pegg RB: Novel synthesis of cooked cured-meat pigment. J Food Sci 5, 1205-1208, 1991.
31. Pierre F, Peiro G, Tache S, Cross AJ, Bingham SA, et al.: New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic Acid. Cancer Epidemiol Biomarkers Prev 15, 2274-2279, 2006.
32. Pierre F, Tache S, Gueraud F, Rerole AL, Jourdan ML, et al.: Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats. Carcinogenesis 28, 321-327, 2007.
33. Gasc N, Tache S, Rathahao E, Bertrand-Michel J, Roques V, et al.: 4- hydroxynonenal in foodstuffs: heme concentration, fatty acid composition and freeze-drying are determining factors. Redox Rep 12, 40-44, 2007.
34. Kuhnle GG and Bingham SA: Dietary meat, endogenous nitrosation and colorectal cancer. Biochem Soc Trans 35, 1355-1357, 2007.
35. Zhou L, Haorah J, Perini F, Carmella SG, Shibamoto T, et al.: Partial purification from hot dogs of N-nitroso compound precursors and their mutagenicity after nitrosation. J Agric Food Chem 54, 5679-5687, 2006.
36. Mirvish SS, Haorah J, Zhou L, Hartman M, Morris CR, et al.: N-nitroso compounds in the gastrointestinal tract of rats and in the feces of mice with induced colitis or fed hot dogs or beef. Carcinogenesis 24, 595-603, 2003.