-
1
-
-
35649013184
-
MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta
-
Abell, A. N., Granger, D. A., and Johnson, G. L. (2007). MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta. J. Biol. Chem. 282, 30476-30484. doi: 10.1074/jbc.M705783200
-
(2007)
J. Biol. Chem
, vol.282
, pp. 30476-30484
-
-
Abell, A.N.1
Granger, D.A.2
Johnson, G.L.3
-
2
-
-
0034704178
-
Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength
-
Alonso, G., Ambrosino, C., Jones, M., and Nebreda, A. R. (2000). Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength. J. Biol. Chem. 275, 40641-40648. doi: 10.1074/jbc.M007835200
-
(2000)
J. Biol. Chem
, vol.275
, pp. 40641-40648
-
-
Alonso, G.1
Ambrosino, C.2
Jones, M.3
Nebreda, A.R.4
-
3
-
-
84956798627
-
Natural products for treatment of osteoporosis: the effects and mechanisms on promoting osteoblast-mediated bone formation
-
An, J., Yang, H., Zhang, Q., Liu, C., Zhao, J., Zhang, L., et al. (2016). Natural products for treatment of osteoporosis: the effects and mechanisms on promoting osteoblast-mediated bone formation. Life Sci. 147, 46-58. doi: 10.1016/j.lfs.2016.01.024
-
(2016)
Life Sci
, vol.147
, pp. 46-58
-
-
An, J.1
Yang, H.2
Zhang, Q.3
Liu, C.4
Zhao, J.5
Zhang, L.6
-
4
-
-
36549069731
-
p38MAP Kinase activity is required for human primary adipocyte differentiation
-
Aouadi, M., Jager, J., Laurent, K., Gonzalez, T., Cormont, M., Binetruy, B., et al. (2007). p38MAP Kinase activity is required for human primary adipocyte differentiation. FEBS Lett. 581, 5591-5596. doi: 10.1016/j.febslet.2007.10.064
-
(2007)
FEBS Lett
, vol.581
, pp. 5591-5596
-
-
Aouadi, M.1
Jager, J.2
Laurent, K.3
Gonzalez, T.4
Cormont, M.5
Binetruy, B.6
-
5
-
-
33644751833
-
Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages
-
Aouadi, M., Laurent, K., Prot, M., Le Marchand-Brustel, Y., Binetruy, B., and Bost, F. (2006). Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages. Diabetes 55, 281-289. doi: 10.2337/diabetes.55.02.06.db05-0963
-
(2006)
Diabetes
, vol.55
, pp. 281-289
-
-
Aouadi, M.1
Laurent, K.2
Prot, M.3
Le Marchand-Brustel, Y.4
Binetruy, B.5
Bost, F.6
-
6
-
-
55549130760
-
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
-
Arimoto, K., Fukuda, H., Imajoh-Ohmi, S., Saito, H., and Takekawa, M. (2008). Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nat. Cell Biol. 10, 1324-1332. doi: 10.1038/ncb1791
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 1324-1332
-
-
Arimoto, K.1
Fukuda, H.2
Imajoh-Ohmi, S.3
Saito, H.4
Takekawa, M.5
-
7
-
-
41949091777
-
Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts
-
Arnott, J. A., Zhang, X., Sanjay, A., Owen, T. A., Smock, S. L., Rehman, S., et al. (2008). Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts. Bone 42, 871-885. doi: 10.1016/j.bone.2008.01.006
-
(2008)
Bone
, vol.42
, pp. 871-885
-
-
Arnott, J.A.1
Zhang, X.2
Sanjay, A.3
Owen, T.A.4
Smock, S.L.5
Rehman, S.6
-
8
-
-
84907581200
-
Mitogen-activated protein kinase (MAPK)-regulated interactions between Osterix and Runx2 are critical for the transcriptional osteogenic program
-
Artigas, N., Ureña, C., Rodriguez-Carballo, E., Rosa, J. L., and Ventura, F. (2014). Mitogen-activated protein kinase (MAPK)-regulated interactions between Osterix and Runx2 are critical for the transcriptional osteogenic program. J. Biol. Chem. 289, 27105-27117. doi: 10.1074/jbc.M114.576793
-
(2014)
J. Biol. Chem
, vol.289
, pp. 27105-27117
-
-
Artigas, N.1
Ureña, C.2
Rodriguez-Carballo, E.3
Rosa, J.L.4
Ventura, F.5
-
9
-
-
84878889208
-
Matrix-embedded osteocytes regulate mobilization of hematopoietic stem/progenitor cells
-
Asada, N., Katayama, Y., Sato, M., Minagawa, K., Wakahashi, K., Kawano, H., et al. (2013). Matrix-embedded osteocytes regulate mobilization of hematopoietic stem/progenitor cells. Cell Stem Cell 12, 737-747. doi: 10.1016/j.stem.2013.05.001
-
(2013)
Cell Stem Cell
, vol.12
, pp. 737-747
-
-
Asada, N.1
Katayama, Y.2
Sato, M.3
Minagawa, K.4
Wakahashi, K.5
Kawano, H.6
-
10
-
-
77958096064
-
The regulation of differentiation in mesenchymal stem cells
-
Augello, A., and De Bari, C. (2010). The regulation of differentiation in mesenchymal stem cells. Hum. Gene Ther. 21, 1226-1238. doi: 10.1089/hum.2010.173
-
(2010)
Hum. Gene Ther
, vol.21
, pp. 1226-1238
-
-
Augello, A.1
De Bari, C.2
-
11
-
-
0030426902
-
Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
-
Badger, A. M., Bradbeer, J. N., Votta, B., Lee, J. C., Adams, J. L., and Griswold, D. E. (1996). Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J. Pharmacol. Exp. Ther. 279, 1453-1461
-
(1996)
J. Pharmacol. Exp. Ther
, vol.279
, pp. 1453-1461
-
-
Badger, A.M.1
Bradbeer, J.N.2
Votta, B.3
Lee, J.C.4
Adams, J.L.5
Griswold, D.E.6
-
12
-
-
36549040859
-
The selectivity of protein kinase inhibitors: a further update
-
Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., et al. (2007). The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408, 297-315. doi: 10.1042/BJ20070797
-
(2007)
Biochem. J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
-
13
-
-
27944461325
-
Generation and characterization of p38beta (MAPK11) gene-targeted mice
-
Beardmore, V. A., Hinton, H. J., Eftychi, C., Apostolaki, M., Armaka, M., Darragh, J., et al. (2005). Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol. Cell. Biol. 25, 10454-10464. doi: 10.1128/MCB.25.23.10454-10464.2005
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10454-10464
-
-
Beardmore, V.A.1
Hinton, H.J.2
Eftychi, C.3
Apostolaki, M.4
Armaka, M.5
Darragh, J.6
-
14
-
-
84943599195
-
Bone development
-
Berendsen, A. D., and Olsen, B. R. (2015). Bone development. Bone 80, 14-18. doi: 10.1016/j.bone.2015.04.035
-
(2015)
Bone
, vol.80
, pp. 14-18
-
-
Berendsen, A.D.1
Olsen, B.R.2
-
15
-
-
77955907279
-
The dual-specificity MAP kinase phosphatases: critical roles in development and cancer
-
Bermudez, O., Pagés, G., and Gimond, C. (2010). The dual-specificity MAP kinase phosphatases: critical roles in development and cancer. Am. J. Physiol. Cell Physiol. 299, C189-C202. doi: 10.1152/ajpcell.00347.2009
-
(2010)
Am. J. Physiol. Cell Physiol
, vol.299
, pp. C189-C202
-
-
Bermudez, O.1
Pagés, G.2
Gimond, C.3
-
16
-
-
84896130272
-
p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice
-
Bernet, J. D., Doles, J. D., Hall, J. K., Kelly Tanaka, K., Carter, T. A., and Olwin, B. B. (2014). p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice. Nat. Med. 20, 265-271. doi: 10.1038/nm.3465
-
(2014)
Nat. Med
, vol.20
, pp. 265-271
-
-
Bernet, J.D.1
Doles, J.D.2
Hall, J.K.3
Kelly Tanaka, K.4
Carter, T.A.5
Olwin, B.B.6
-
17
-
-
68949173918
-
Beta-arrestin2 regulates parathyroid hormone effects on a p38 MAPK and NFkappaB gene expression network in osteoblasts
-
Bianchi, E. N., and Ferrari, S. L. (2009). Beta-arrestin2 regulates parathyroid hormone effects on a p38 MAPK and NFkappaB gene expression network in osteoblasts. Bone 45, 716-725. doi: 10.1016/j.bone.2009.06.020
-
(2009)
Bone
, vol.45
, pp. 716-725
-
-
Bianchi, E.N.1
Ferrari, S.L.2
-
18
-
-
59149098536
-
p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta
-
Bikkavilli, R. K., Feigin, M. E., and Malbon, C. C. (2008). p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta. J. Cell Sci. 121, 3598-3607. doi: 10.1242/jcs.032854
-
(2008)
J. Cell Sci
, vol.121
, pp. 3598-3607
-
-
Bikkavilli, R.K.1
Feigin, M.E.2
Malbon, C.C.3
-
19
-
-
84885115199
-
Crosstalk between tyrosine kinase receptors, GSK3 and BMP2 signaling during osteoblastic differentiation of human mesenchymal stem cells
-
Biver, E., Thouverey, C., Magne, D., and Caverzasio, J. (2014). Crosstalk between tyrosine kinase receptors, GSK3 and BMP2 signaling during osteoblastic differentiation of human mesenchymal stem cells. Mol. Cell. Endocrinol. 382, 120-130. doi: 10.1016/j.mce.2013.09.018
-
(2014)
Mol. Cell. Endocrinol
, vol.382
, pp. 120-130
-
-
Biver, E.1
Thouverey, C.2
Magne, D.3
Caverzasio, J.4
-
20
-
-
84990985937
-
Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts
-
Bouvard, B., Abed, E., Yéléhé-Okouma, M., Bianchi, A., Mainard, D., Netter, P., et al. (2014). Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts. Arthritis Res. Ther. 16:459. doi: 10.1186/s13075-014-0459-3
-
(2014)
Arthritis Res. Ther
, vol.16
, pp. 459
-
-
Bouvard, B.1
Abed, E.2
Yéléhé-Okouma, M.3
Bianchi, A.4
Mainard, D.5
Netter, P.6
-
21
-
-
0041660960
-
Mechanism of p38 MAP kinase activation in vivo
-
Brancho, D., Tanaka, N., Jaeschke, A., Ventura, J. J., Kelkar, N., Tanaka, Y., et al. (2003). Mechanism of p38 MAP kinase activation in vivo. Genes Dev. 17, 1969-1978. doi: 10.1101/gad.1107303
-
(2003)
Genes Dev
, vol.17
, pp. 1969-1978
-
-
Brancho, D.1
Tanaka, N.2
Jaeschke, A.3
Ventura, J.J.4
Kelkar, N.5
Tanaka, Y.6
-
22
-
-
84883437373
-
p38alpha MAPK regulates adult muscle stem cell fate by restricting progenitor proliferation during postnatal growth and repair
-
Brien, P., Pugazhendhi, D., Woodhouse, S., Oxley, D., and Pell, J. M. (2013). p38alpha MAPK regulates adult muscle stem cell fate by restricting progenitor proliferation during postnatal growth and repair. Stem Cells 31, 1597-1610. doi: 10.1002/stem.1399
-
(2013)
Stem Cells
, vol.31
, pp. 1597-1610
-
-
Brien, P.1
Pugazhendhi, D.2
Woodhouse, S.3
Oxley, D.4
Pell, J.M.5
-
23
-
-
79952435349
-
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases
-
Cargnello, M., and Roux, P. P. (2011). Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol. Mol. Biol. Rev. 75, 50-83. doi: 10.1128/MMBR.00031-10
-
(2011)
Microbiol. Mol. Biol. Rev
, vol.75
, pp. 50-83
-
-
Cargnello, M.1
Roux, P.P.2
-
24
-
-
43149125403
-
Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms
-
Caverzasio, J. (2008). Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms. Bone 42, 1131-1136. doi: 10.1016/j.bone.2008.02.010
-
(2008)
Bone
, vol.42
, pp. 1131-1136
-
-
Caverzasio, J.1
-
25
-
-
50249134851
-
Prevention of trabecular bone loss induced by estrogen deficiency by a selective p38alpha inhibitor
-
Caverzasio, J., Higgins, L., and Ammann, P. (2008). Prevention of trabecular bone loss induced by estrogen deficiency by a selective p38alpha inhibitor. J. Bone Miner. Res. 23, 1389-1397. doi: 10.1359/jbmr.080410
-
(2008)
J. Bone Miner. Res
, vol.23
, pp. 1389-1397
-
-
Caverzasio, J.1
Higgins, L.2
Ammann, P.3
-
26
-
-
35548978540
-
Essential role of Wnt3a-mediated activation of mitogen-activated protein kinase p38 for the stimulation of alkaline phosphatase activity and matrix mineralization in C3H10T1/2 mesenchymal cells
-
Caverzasio, J., and Manen, D. (2007). Essential role of Wnt3a-mediated activation of mitogen-activated protein kinase p38 for the stimulation of alkaline phosphatase activity and matrix mineralization in C3H10T1/2 mesenchymal cells. Endocrinology 148, 5323-5330. doi: 10.1210/en.2007-0520
-
(2007)
Endocrinology
, vol.148
, pp. 5323-5330
-
-
Caverzasio, J.1
Manen, D.2
-
27
-
-
79953777185
-
Activation of FGF receptors is a new mechanism by which strontium ranelate induces osteoblastic cell growth
-
Caverzasio, J., and Thouverey, C. (2011). Activation of FGF receptors is a new mechanism by which strontium ranelate induces osteoblastic cell growth. Cell. Physiol. Biochem. 27, 243-250. doi: 10.1159/000327950
-
(2011)
Cell. Physiol. Biochem
, vol.27
, pp. 243-250
-
-
Caverzasio, J.1
Thouverey, C.2
-
28
-
-
24744462930
-
BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways
-
Celil, A. B., and Campbell, P. G. (2005). BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways. J. Biol. Chem. 280, 31353-31359. doi: 10.1074/jbc.M503845200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 31353-31359
-
-
Celil, A.B.1
Campbell, P.G.2
-
29
-
-
78751692388
-
Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6
-
Cervenka, I., Wolf, J., Mašek, J., Krejci, P., Wilcox, W. R., Kozubik, A., et al. (2011). Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Mol. Cell. Biol. 31, 179-189. doi: 10.1128/MCB.00550-10
-
(2011)
Mol. Cell. Biol
, vol.31
, pp. 179-189
-
-
Cervenka, I.1
Wolf, J.2
Mašek, J.3
Krejci, P.4
Wilcox, W.R.5
Kozubik, A.6
-
30
-
-
84880053827
-
Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression
-
Chandra, A., Lan, S., Zhu, J., Siclari, V. A., and Qin, L. (2013). Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression. J. Biol. Chem. 288, 20488-20498. doi: 10.1074/jbc.M112.447250
-
(2013)
J. Biol. Chem
, vol.288
, pp. 20488-20498
-
-
Chandra, A.1
Lan, S.2
Zhu, J.3
Siclari, V.A.4
Qin, L.5
-
31
-
-
78349285893
-
Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/beta-catenin canonical Wnt signaling
-
Chen, J. R., Lazarenko, O. P., Wu, X., Kang, J., Blackburn, M. L., Shankar, K., et al. (2010). Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/beta-catenin canonical Wnt signaling. J. Bone Miner. Res. 25, 2399-2411. doi: 10.1002/jbmr.137
-
(2010)
J. Bone Miner. Res
, vol.25
, pp. 2399-2411
-
-
Chen, J.R.1
Lazarenko, O.P.2
Wu, X.3
Kang, J.4
Blackburn, M.L.5
Shankar, K.6
-
32
-
-
79751526399
-
8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription
-
Chiou, W. F., Lee, C. H., Liao, J. F., and Chen, C. C. (2011). 8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription. Life Sci. 88, 335-342. doi: 10.1016/j.lfs.2010.12.009
-
(2011)
Life Sci
, vol.88
, pp. 335-342
-
-
Chiou, W.F.1
Lee, C.H.2
Liao, J.F.3
Chen, C.C.4
-
33
-
-
40949129120
-
Ultrasound stimulates MMP-13 expression through p38 and JNK pathway in osteoblasts
-
Chiu, Y. C., Huang, T. H., Fu, W. M., Yang, R. S., and Tang, C. H. (2008). Ultrasound stimulates MMP-13 expression through p38 and JNK pathway in osteoblasts. J. Cell. Physiol. 215, 356-365. doi: 10.1002/jcp.21322
-
(2008)
J. Cell. Physiol
, vol.215
, pp. 356-365
-
-
Chiu, Y.C.1
Huang, T.H.2
Fu, W.M.3
Yang, R.S.4
Tang, C.H.5
-
34
-
-
84882593558
-
Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase
-
Choi, H. R., Kim, W. K., Kim, E. Y., Han, B. S., Min, J. K., Chi, S. W., et al. (2013). Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. PLoS ONE 8:e72340. doi: 10.1371/journal.pone.0072340
-
(2013)
PLoS ONE
, vol.8
-
-
Choi, H.R.1
Kim, W.K.2
Kim, E.Y.3
Han, B.S.4
Min, J.K.5
Chi, S.W.6
-
35
-
-
77955059513
-
Mechanisms and functions of p38 MAPK signalling
-
Cuadrado, A., and Nebreda, A. R. (2010). Mechanisms and functions of p38 MAPK signalling. Biochem. J. 429, 403-417. doi: 10.1042/BJ20100323
-
(2010)
Biochem. J
, vol.429
, pp. 403-417
-
-
Cuadrado, A.1
Nebreda, A.R.2
-
36
-
-
0033548233
-
Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis
-
Cuenda, A., and Cohen, P. (1999). Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis. J. Biol. Chem. 274, 4341-4346. doi: 10.1074/jbc.274.7.4341
-
(1999)
J. Biol. Chem
, vol.274
, pp. 4341-4346
-
-
Cuenda, A.1
Cohen, P.2
-
37
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
Cuenda, A., Rouse, J., Doza, Y. N., Meier, R., Cohen, P., Gallagher, T. F., et al. (1995). SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364, 229-233. doi: 10.1016/0014-5793(95)00357-F
-
(1995)
FEBS Lett
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
Meier, R.4
Cohen, P.5
Gallagher, T.F.6
-
38
-
-
84905230198
-
Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration
-
Czaplinska, D., Turczyk, L., Grudowska, A., Mieszkowska, M., Lipinska, A. D., Skladanowski, A. C., et al. (2014). Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration. Biochim. Biophys. Acta 1843, 2461-2470. doi: 10.1016/j.bbamcr.2014.06.022
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 2461-2470
-
-
Czaplinska, D.1
Turczyk, L.2
Grudowska, A.3
Mieszkowska, M.4
Lipinska, A.D.5
Skladanowski, A.C.6
-
39
-
-
33645007357
-
TNFalpha and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics
-
Dai, J. C., He, P., Chen, X., and Greenfield, E. M. (2006). TNFalpha and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics. Bone 38, 509-520. doi: 10.1016/j.bone.2005.10.007
-
(2006)
Bone
, vol.38
, pp. 509-520
-
-
Dai, J.C.1
He, P.2
Chen, X.3
Greenfield, E.M.4
-
40
-
-
0037077212
-
Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts A cellular mechanism for release of TGF-beta from bone matrix
-
Dallas, S. L., Rosser, J. L., Mundy, G. R., and Bonewald, L. F. (2002). Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix. J. Biol. Chem. 277, 21352-21360. doi: 10.1074/jbc.M111663200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 21352-21360
-
-
Dallas, S.L.1
Rosser, J.L.2
Mundy, G.R.3
Bonewald, L.F.4
-
41
-
-
34548566067
-
Cyclin D1 as a target for the proliferative effects of PTH and PTHrP in early osteoblastic cells
-
Datta, N. S., Pettway, G. J., Chen, C., Koh, A. J., and McCauley, L. K. (2007). Cyclin D1 as a target for the proliferative effects of PTH and PTHrP in early osteoblastic cells. J. Bone Miner. Res. 22, 951-964. doi: 10.1359/jbmr.070328
-
(2007)
J. Bone Miner. Res
, vol.22
, pp. 951-964
-
-
Datta, N.S.1
Pettway, G.J.2
Chen, C.3
Koh, A.J.4
McCauley, L.K.5
-
42
-
-
0035096602
-
Fibroblast growth factor-2 (FGF-2) increases N-cadherin expression through protein kinase C and Src-kinase pathways in human calvaria osteoblasts
-
Debiais, F., Lemonnier, J., Hay, E., Delannoy, P., Caverzasio, J., and Marie, P. J. (2001). Fibroblast growth factor-2 (FGF-2) increases N-cadherin expression through protein kinase C and Src-kinase pathways in human calvaria osteoblasts. J. Cell. Biochem. 81, 68-81. doi: 10.1002/1097-4644(20010401)81:1<68::AID-JCB1024>3.0.CO;2-S
-
(2001)
J. Cell. Biochem
, vol.81
, pp. 68-81
-
-
Debiais, F.1
Lemonnier, J.2
Hay, E.3
Delannoy, P.4
Caverzasio, J.5
Marie, P.J.6
-
43
-
-
84919884431
-
Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx-/-mice
-
de la Croix Ndong, J., Stevens, D. M., Vignaux, G., Uppuganti, S., Perrien, D. S., Yang, X., et al. (2015). Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx-/-mice. J. Bone Miner. Res. 30, 55-63. doi: 10.1002/jbmr.2316
-
(2015)
J. Bone Miner. Res
, vol.30
, pp. 55-63
-
-
de la Croix Ndong, J.1
Stevens, D.M.2
Vignaux, G.3
Uppuganti, S.4
Perrien, D.S.5
Yang, X.6
-
44
-
-
18144429118
-
MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex
-
de la Serna, I. L., Ohkawa, Y., Berkes, C. A., Bergstrom, D. A., Dacwag, C. S., Tapscott, S. J., et al. (2005). MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex. Mol. Cell. Biol. 25, 3997-4009. doi: 10.1128/MCB.25.10.3997-4009.2005
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 3997-4009
-
-
de la Serna, I.L.1
Ohkawa, Y.2
Berkes, C.A.3
Bergstrom, D.A.4
Dacwag, C.S.5
Tapscott, S.J.6
-
45
-
-
79961213639
-
Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development
-
del Barco Barrantes, I., Coya, J. M., Maina, F., Arthur, J. S., and Nebreda, A. R. (2011). Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development. Proc. Natl. Acad. Sci. U.S.A. 108, 12764-12769. doi: 10.1073/pnas.1015013108
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 12764-12769
-
-
del Barco Barrantes, I.1
Coya, J.M.2
Maina, F.3
Arthur, J.S.4
Nebreda, A.R.5
-
46
-
-
34248525404
-
Scaffold proteins of MAP-kinase modules
-
Dhanasekaran, D. N., Kashef, K., Lee, C. M., Xu, H., and Reddy, E. P. (2007). Scaffold proteins of MAP-kinase modules. Oncogene 26, 3185-3202. doi: 10.1038/sj.onc.1210411
-
(2007)
Oncogene
, vol.26
, pp. 3185-3202
-
-
Dhanasekaran, D.N.1
Kashef, K.2
Lee, C.M.3
Xu, H.4
Reddy, E.P.5
-
47
-
-
78449236974
-
Calcium-mediated stress kinase activation by DMP1 promotes osteoblast differentiation
-
Eapen, A., Sundivakkam, P., Song, Y., Ravindran, S., Ramachandran, A., Tiruppathi, C., et al. (2010). Calcium-mediated stress kinase activation by DMP1 promotes osteoblast differentiation. J. Biol. Chem. 285, 36339-36351. doi: 10.1074/jbc.M110.145607
-
(2010)
J. Biol. Chem
, vol.285
, pp. 36339-36351
-
-
Eapen, A.1
Sundivakkam, P.2
Song, Y.3
Ravindran, S.4
Ramachandran, A.5
Tiruppathi, C.6
-
48
-
-
84954155743
-
A p38 mitogen-activated protein kinase-regulated myocyte enhancer factor 2-beta-catenin interaction enhances canonical Wnt signaling
-
Ehyai, S., Dionyssiou, M. G., Gordon, J. W., Williams, D., Siu, K. W., and McDermott, J. C. (2015). A p38 mitogen-activated protein kinase-regulated myocyte enhancer factor 2-beta-catenin interaction enhances canonical Wnt signaling. Mol. Cell. Biol. 36, 330-346. doi: 10.1128/MCB.00832-15
-
(2015)
Mol. Cell. Biol
, vol.36
, pp. 330-346
-
-
Ehyai, S.1
Dionyssiou, M.G.2
Gordon, J.W.3
Williams, D.4
Siu, K.W.5
McDermott, J.C.6
-
49
-
-
0033544862
-
Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis
-
Engelman, J. A., Berg, A. H., Lewis, R. Y., Lin, A., Lisanti, M. P., and Scherer, P. E. (1999). Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. J. Biol. Chem. 274, 35630-35638. doi: 10.1074/jbc.274.50.35630
-
(1999)
J. Biol. Chem
, vol.274
, pp. 35630-35638
-
-
Engelman, J.A.1
Berg, A.H.2
Lewis, R.Y.3
Lin, A.4
Lisanti, M.P.5
Scherer, P.E.6
-
50
-
-
0033610788
-
Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis
-
Engelman, J. A., Lisanti, M. P., and Scherer, P. E. (1998). Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J. Biol. Chem. 273, 32111-32120. doi: 10.1074/jbc.273.48.32111
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32111-32120
-
-
Engelman, J.A.1
Lisanti, M.P.2
Scherer, P.E.3
-
51
-
-
84908372576
-
Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways
-
Feng, M., Tian, L., Gan, L., Liu, Z., and Sun, C. (2014). Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways. Biol. Cell 106, 294-307. doi: 10.1111/boc.201400004
-
(2014)
Biol. Cell
, vol.106
, pp. 294-307
-
-
Feng, M.1
Tian, L.2
Gan, L.3
Liu, Z.4
Sun, C.5
-
52
-
-
84962493544
-
Mitogen-dependent regulation of DUSP1 governs ERK and p38 signaling during early 3T3-L1 adipocyte differentiation
-
Ferguson, B. S., Nam, H., Stephens, J. M., and Morrison, R. F. (2016). Mitogen-dependent regulation of DUSP1 governs ERK and p38 signaling during early 3T3-L1 adipocyte differentiation. J. Cell Physiol. 231, 1562-1574. doi: 10.1002/jcp.25248
-
(2016)
J. Cell Physiol
, vol.231
, pp. 1562-1574
-
-
Ferguson, B.S.1
Nam, H.2
Stephens, J.M.3
Morrison, R.F.4
-
53
-
-
37249028142
-
Transcriptional regulation of osteoblasts
-
Franceschi, R. T., Ge, C., Xiao, G., Roca, H., and Jiang, D. (2007). Transcriptional regulation of osteoblasts. Ann. N.Y. Acad. Sci. 1116, 196-207. doi: 10.1196/annals.1402.081
-
(2007)
Ann. N.Y. Acad. Sci
, vol.1116
, pp. 196-207
-
-
Franceschi, R.T.1
Ge, C.2
Xiao, G.3
Roca, H.4
Jiang, D.5
-
54
-
-
33644975844
-
Buried alive: how osteoblasts become osteocytes
-
Franz-Odendaal, T. A., Hall, B. K., and Witten, P. E. (2006). Buried alive: how osteoblasts become osteocytes. Dev. Dyn. 235, 176-190. doi: 10.1002/dvdy.20603
-
(2006)
Dev. Dyn
, vol.235
, pp. 176-190
-
-
Franz-Odendaal, T.A.1
Hall, B.K.2
Witten, P.E.3
-
55
-
-
62449127652
-
Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing
-
Fu, X., Han, B., Cai, S., Lei, Y., Sun, T., and Sheng, Z. (2009). Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing. Wound Repair Regen. 17, 185-191. doi: 10.1111/j.1524-475X.2009.00454.x
-
(2009)
Wound Repair Regen
, vol.17
, pp. 185-191
-
-
Fu, X.1
Han, B.2
Cai, S.3
Lei, Y.4
Sun, T.5
Sheng, Z.6
-
56
-
-
36248995245
-
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
-
Fuentealba, L. C., Eivers, E., Ikeda, A., Hurtado, C., Kuroda, H., Pera, E. M., et al. (2007). Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131, 980-993. doi: 10.1016/j.cell.2007.09.027
-
(2007)
Cell
, vol.131
, pp. 980-993
-
-
Fuentealba, L.C.1
Eivers, E.2
Ikeda, A.3
Hurtado, C.4
Kuroda, H.5
Pera, E.M.6
-
57
-
-
79955657268
-
TGF-beta-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts
-
Fukuno, N., Matsui, H., Kanda, Y., Suzuki, O., Matsumoto, K., Sasaki, K., et al. (2011). TGF-beta-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts. Biochem. Biophys. Res. Commun. 408, 202-207. doi: 10.1016/j.bbrc.2011.02.127
-
(2011)
Biochem. Biophys. Res. Commun
, vol.408
, pp. 202-207
-
-
Fukuno, N.1
Matsui, H.2
Kanda, Y.3
Suzuki, O.4
Matsumoto, K.5
Sasaki, K.6
-
58
-
-
0035046919
-
Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells
-
Gallea, S., Lallemand, F., Atfi, A., Rawadi, G., Ramez, V., Spinella-Jaegle, S., et al. (2001). Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells. Bone 28, 491-498. doi: 10.1016/S8756-3282(01)00415-X
-
(2001)
Bone
, vol.28
, pp. 491-498
-
-
Gallea, S.1
Lallemand, F.2
Atfi, A.3
Rawadi, G.4
Ramez, V.5
Spinella-Jaegle, S.6
-
59
-
-
59349086946
-
BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity
-
Gamell, C., Osses, N., Bartrons, R., Ruckle, T., Camps, M., Rosa, J. L., et al. (2008). BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity. J. Cell Sci. 121, 3960-3970. doi: 10.1242/jcs.031286
-
(2008)
J. Cell Sci
, vol.121
, pp. 3960-3970
-
-
Gamell, C.1
Osses, N.2
Bartrons, R.3
Ruckle, T.4
Camps, M.5
Rosa, J.L.6
-
60
-
-
79551522570
-
The p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migration
-
Gamell, C., Susperregui, A. G., Bernard, O., Rosa, J. L., and Ventura, F. (2011). The p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migration. PLoS ONE 6:e16477. doi: 10.1371/journal.pone.0016477
-
(2011)
PLoS ONE
, vol.6
-
-
Gamell, C.1
Susperregui, A.G.2
Bernard, O.3
Rosa, J.L.4
Ventura, F.5
-
61
-
-
84943141931
-
Separating myoblast differentiation from muscle cell fusion using IGF-I and the p38 MAP kinase inhibitor SB202190
-
Gardner, S., Gross, S. M., David, L. L., Klimek, J. E., and Rotwein, P. (2015). Separating myoblast differentiation from muscle cell fusion using IGF-I and the p38 MAP kinase inhibitor SB202190. Am. J. Physiol. Cell Physiol. 309, C491-C500. doi: 10.1152/ajpcell.00184.2015
-
(2015)
Am. J. Physiol. Cell Physiol
, vol.309
, pp. C491-C500
-
-
Gardner, S.1
Gross, S.M.2
David, L.L.3
Klimek, J.E.4
Rotwein, P.5
-
62
-
-
33847375078
-
Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development
-
Ge, C., Xiao, G., Jiang, D., and Franceschi, R. T. (2007). Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J. Cell Biol. 176, 709-718. doi: 10.1083/jcb.200610046
-
(2007)
J. Cell Biol
, vol.176
, pp. 709-718
-
-
Ge, C.1
Xiao, G.2
Jiang, D.3
Franceschi, R.T.4
-
63
-
-
70450230468
-
Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor
-
Ge, C., Xiao, G., Jiang, D., Yang, Q., Hatch, N. E., Roca, H., et al. (2009). Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor. J. Biol. Chem. 284, 32533-32543. doi: 10.1074/jbc.M109.040980
-
(2009)
J. Biol. Chem
, vol.284
, pp. 32533-32543
-
-
Ge, C.1
Xiao, G.2
Jiang, D.3
Yang, Q.4
Hatch, N.E.5
Roca, H.6
-
64
-
-
84857320794
-
Interactions between extracellular signal-regulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity
-
Ge, C., Yang, Q., Zhao, G., Yu, H., Kirkwood, K. L., and Franceschi, R. T. (2012). Interactions between extracellular signal-regulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity. J. Bone Miner. Res. 27, 538-551. doi: 10.1002/jbmr.561
-
(2012)
J. Bone Miner. Res
, vol.27
, pp. 538-551
-
-
Ge, C.1
Yang, Q.2
Zhao, G.3
Yu, H.4
Kirkwood, K.L.5
Franceschi, R.T.6
-
65
-
-
0042416621
-
Specific contribution of estrogen receptors on mitogen-activated protein kinase pathways and vascular cell activation
-
Geraldes, P., Sirois, M. G., and Tanguay, J. F. (2003). Specific contribution of estrogen receptors on mitogen-activated protein kinase pathways and vascular cell activation. Circ. Res. 93, 399-405. doi: 10.1161/01.RES.0000088640.18462.42
-
(2003)
Circ. Res
, vol.93
, pp. 399-405
-
-
Geraldes, P.1
Sirois, M.G.2
Tanguay, J.F.3
-
66
-
-
0034814966
-
MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes in mechanical environment in osteoblasts
-
Granet, C., Boutahar, N., Vico, L., Alexandre, C., and Lafage-Proust, M. H. (2001). MAPK and SRC-kinases control EGR-1 and NF-kappa B inductions by changes in mechanical environment in osteoblasts. Biochem. Biophys. Res. Commun. 284, 622-631. doi: 10.1006/bbrc.2001.5023
-
(2001)
Biochem. Biophys. Res. Commun
, vol.284
, pp. 622-631
-
-
Granet, C.1
Boutahar, N.2
Vico, L.3
Alexandre, C.4
Lafage-Proust, M.H.5
-
67
-
-
84884505578
-
Mitogen-activated protein kinase pathways in osteoblasts
-
Greenblatt, M. B., Shim, J. H., and Glimcher, L. H. (2013). Mitogen-activated protein kinase pathways in osteoblasts. Annu. Rev. Cell Dev. Biol. 29, 63-79. doi: 10.1146/annurev-cellbio-101512-122347
-
(2013)
Annu. Rev. Cell Dev. Biol
, vol.29
, pp. 63-79
-
-
Greenblatt, M.B.1
Shim, J.H.2
Glimcher, L.H.3
-
68
-
-
77954972964
-
The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice
-
Greenblatt, M. B., Shim, J. H., Zou, W., Sitara, D., Schweitzer, M., Hu, D., et al. (2010). The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J. Clin. Invest. 120, 2457-2473. doi: 10.1172/JCI42285
-
(2010)
J. Clin. Invest
, vol.120
, pp. 2457-2473
-
-
Greenblatt, M.B.1
Shim, J.H.2
Zou, W.3
Sitara, D.4
Schweitzer, M.5
Hu, D.6
-
69
-
-
23044515502
-
The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix
-
Gregory, K. E., Ono, R. N., Charbonneau, N. L., Kuo, C. L., Keene, D. R., Bachinger, H. P., et al. (2005). The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix. J. Biol. Chem. 280, 27970-27980. doi: 10.1074/jbc.M504270200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 27970-27980
-
-
Gregory, K.E.1
Ono, R.N.2
Charbonneau, N.L.3
Kuo, C.L.4
Keene, D.R.5
Bachinger, H.P.6
-
70
-
-
0242664611
-
Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation
-
Guicheux, J., Lemonnier, J., Ghayor, C., Suzuki, A., Palmer, G., and Caverzasio, J. (2003). Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation. J. Bone Miner. Res. 18, 2060-2068. doi: 10.1359/jbmr.2003.18.11.2060
-
(2003)
J. Bone Miner. Res
, vol.18
, pp. 2060-2068
-
-
Guicheux, J.1
Lemonnier, J.2
Ghayor, C.3
Suzuki, A.4
Palmer, G.5
Caverzasio, J.6
-
71
-
-
84881153583
-
JNK signaling plays an important role in the effects of TNF-alpha and IL-1beta on in vitro osteoblastic differentiation of cultured human periosteal-derived cells
-
Hah, Y. S., Kang, H. G., Cho, H. Y., Shin, S. H., Kim, U. K., Park, B. W., et al. (2013). JNK signaling plays an important role in the effects of TNF-alpha and IL-1beta on in vitro osteoblastic differentiation of cultured human periosteal-derived cells. Mol. Biol. Rep. 40, 4869-4881. doi: 10.1007/s11033-013-2586-3
-
(2013)
Mol. Biol. Rep
, vol.40
, pp. 4869-4881
-
-
Hah, Y.S.1
Kang, H.G.2
Cho, H.Y.3
Shin, S.H.4
Kim, U.K.5
Park, B.W.6
-
72
-
-
84886936036
-
New insights in osteogenic differentiation revealed by mass spectrometric assessment of phosphorylated substrates in murine skin mesenchymal cells
-
Halcsik, E., Forni, M. F., Fujita, A., Verano-Braga, T., Jensen, O. N., and Sogayar, M. C. (2013). New insights in osteogenic differentiation revealed by mass spectrometric assessment of phosphorylated substrates in murine skin mesenchymal cells. BMC Cell Biol. 14:47. doi: 10.1186/1471-2121-14-47
-
(2013)
BMC Cell Biol
, vol.14
, pp. 47
-
-
Halcsik, E.1
Forni, M.F.2
Fujita, A.3
Verano-Braga, T.4
Jensen, O.N.5
Sogayar, M.C.6
-
73
-
-
84864063438
-
RhoA-mediated signaling in mechanotransduction of osteoblasts
-
Hamamura, K., Swarnkar, G., Tanjung, N., Cho, E., Li, J., Na, S., et al. (2012). RhoA-mediated signaling in mechanotransduction of osteoblasts. Connect. Tissue Res. 53, 398-406. doi: 10.3109/03008207.2012.671398
-
(2012)
Connect. Tissue Res
, vol.53
, pp. 398-406
-
-
Hamamura, K.1
Swarnkar, G.2
Tanjung, N.3
Cho, E.4
Li, J.5
Na, S.6
-
74
-
-
0037323398
-
Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis
-
Hata, K., Nishimura, R., Ikeda, F., Yamashita, K., Matsubara, T., Nokubi, T., et al. (2003). Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis. Mol. Biol. Cell 14, 545-555. doi: 10.1091/mbc.E02-06-0356
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 545-555
-
-
Hata, K.1
Nishimura, R.2
Ikeda, F.3
Yamashita, K.4
Matsubara, T.5
Nokubi, T.6
-
75
-
-
0037403844
-
BMP signals regulate Dlx5 during early avian skull development
-
Holleville, N., Quilhac, A., Bontoux, M., and Monsoro-Burq, A. H. (2003). BMP signals regulate Dlx5 during early avian skull development. Dev. Biol. 257, 177-189. doi: 10.1016/S0012-1606(03)00059-9
-
(2003)
Dev. Biol
, vol.257
, pp. 177-189
-
-
Holleville, N.1
Quilhac, A.2
Bontoux, M.3
Monsoro-Burq, A.H.4
-
76
-
-
0034193219
-
Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons
-
Honda, K., Sawada, H., Kihara, T., Urushitani, M., Nakamizo, T., Akaike, A., et al. (2000). Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons. J. Neurosci. Res. 60, 321-327. doi: 10.1002/(SICI)1097-4547(20000501)60:3<321::AID-JNR6>3.0.CO;2-T
-
(2000)
J. Neurosci. Res
, vol.60
, pp. 321-327
-
-
Honda, K.1
Sawada, H.2
Kihara, T.3
Urushitani, M.4
Nakamizo, T.5
Akaike, A.6
-
77
-
-
69149091047
-
BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
-
Huang, H., Song, T. J., Li, X., Hu, L., He, Q., Liu, M., et al. (2009). BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc. Natl. Acad. Sci. U.S.A. 106, 12670-12675. doi: 10.1073/pnas.0906266106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 12670-12675
-
-
Huang, H.1
Song, T.J.2
Li, X.3
Hu, L.4
He, Q.5
Liu, M.6
-
78
-
-
84901006699
-
Opposing TNF-alpha/IL-1beta-and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation
-
Huang, R. L., Yuan, Y., Tu, J., Zou, G. M., and Li, Q. (2014). Opposing TNF-alpha/IL-1beta-and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation. Cell Death Disease 5:e1187. doi: 10.1038/cddis.2014.101
-
(2014)
Cell Death Disease
, vol.5
-
-
Huang, R.L.1
Yuan, Y.2
Tu, J.3
Zou, G.M.4
Li, Q.5
-
79
-
-
84859902202
-
c-Jun N-terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104
-
Huang, Y. F., Lin, J. J., Lin, C. H., Su, Y., and Hung, S. C. (2012). c-Jun N-terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104. J. Bone Miner. Res. 27, 1093-1105. doi: 10.1002/jbmr.1548
-
(2012)
J. Bone Miner. Res
, vol.27
, pp. 1093-1105
-
-
Huang, Y.F.1
Lin, J.J.2
Lin, C.H.3
Su, Y.4
Hung, S.C.5
-
80
-
-
84966269445
-
The role of osteoclast differentiation and function in skeletal homeostasis
-
Ikeda, K., and Takeshita, S. (2016). The role of osteoclast differentiation and function in skeletal homeostasis. J. Biochem. 159, 1-8. doi: 10.1093/jb/mvv112
-
(2016)
J. Biochem
, vol.159
, pp. 1-8
-
-
Ikeda, K.1
Takeshita, S.2
-
81
-
-
0033543653
-
Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2
-
Iwasaki, S., Iguchi, M., Watanabe, K., Hoshino, R., Tsujimoto, M., and Kohno, M. (1999). Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2. J. Biol. Chem. 274, 26503-26510. doi: 10.1074/jbc.274.37.26503
-
(1999)
J. Biol. Chem
, vol.274
, pp. 26503-26510
-
-
Iwasaki, S.1
Iguchi, M.2
Watanabe, K.3
Hoshino, R.4
Tsujimoto, M.5
Kohno, M.6
-
82
-
-
0034737742
-
Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase
-
Jaiswal, R. K., Jaiswal, N., Bruder, S. P., Mbalaviele, G., Marshak, D. R., and Pittenger, M. F. (2000). Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase. J. Biol. Chem. 275, 9645-9652. doi: 10.1074/jbc.275.13.9645
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9645-9652
-
-
Jaiswal, R.K.1
Jaiswal, N.2
Bruder, S.P.3
Mbalaviele, G.4
Marshak, D.R.5
Pittenger, M.F.6
-
83
-
-
78049439172
-
Saponins from the roots of Platycodon grandiflorum stimulate osteoblast differentiation via p38 MAPK-and ERK-dependent RUNX2 activation
-
Jeong, H. M., Han, E. H., Jin, Y. H., Hwang, Y. P., Kim, H. G., Park, B. H., et al. (2010). Saponins from the roots of Platycodon grandiflorum stimulate osteoblast differentiation via p38 MAPK-and ERK-dependent RUNX2 activation. Food Chem. Toxicol. 48, 3362-3368. doi: 10.1016/j.fct.2010.09.005
-
(2010)
Food Chem. Toxicol
, vol.48
, pp. 3362-3368
-
-
Jeong, H.M.1
Han, E.H.2
Jin, Y.H.3
Hwang, Y.P.4
Kim, H.G.5
Park, B.H.6
-
84
-
-
84937762922
-
(2S)-7,4'-dihydroxy-8-prenylflavan stimulates adipogenesis and glucose uptake through p38MAPK pathway in 3T3-L1 cells
-
Ji, J., Zhu, J., Hu, X., Wang, T., Zhang, X., Hou, A. J., et al. (2015). (2S)-7,4'-dihydroxy-8-prenylflavan stimulates adipogenesis and glucose uptake through p38MAPK pathway in 3T3-L1 cells. Biochem. Biophys. Res. Commun. 460, 578-582. doi: 10.1016/j.bbrc.2015.03.072
-
(2015)
Biochem. Biophys. Res. Commun
, vol.460
, pp. 578-582
-
-
Ji, J.1
Zhu, J.2
Hu, X.3
Wang, T.4
Zhang, X.5
Hou, A.J.6
-
85
-
-
17644404437
-
The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell
-
Jones, N. C., Tyner, K. J., Nibarger, L., Stanley, H. M., Cornelison, D. D., Fedorov, Y. V., et al. (2005). The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell. J. Cell Biol. 169, 105-116. doi: 10.1083/jcb.200408066
-
(2005)
J. Cell Biol
, vol.169
, pp. 105-116
-
-
Jones, N.C.1
Tyner, K.J.2
Nibarger, L.3
Stanley, H.M.4
Cornelison, D.D.5
Fedorov, Y.V.6
-
86
-
-
1842633468
-
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells
-
Kakita, A., Suzuki, A., Ono, Y., Miura, Y., Itoh, M., and Oiso, Y. (2004). Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells. Prostaglandins Leukot. Essent. Fatty Acids 70, 469-474. doi: 10.1016/j.plefa.2003.09.003
-
(2004)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.70
, pp. 469-474
-
-
Kakita, A.1
Suzuki, A.2
Ono, Y.3
Miura, Y.4
Itoh, M.5
Oiso, Y.6
-
87
-
-
77953381255
-
Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts
-
Kamiya, N., Kobayashi, T., Mochida, Y., Yu, P. B., Yamauchi, M., Kronenberg, H. M., et al. (2010). Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J. Bone Miner. Res. 25, 200-210. doi: 10.1359/jbmr.090806
-
(2010)
J. Bone Miner. Res
, vol.25
, pp. 200-210
-
-
Kamiya, N.1
Kobayashi, T.2
Mochida, Y.3
Yu, P.B.4
Yamauchi, M.5
Kronenberg, H.M.6
-
88
-
-
84855987634
-
The contribution of bone to whole-organism physiology
-
Karsenty, G., and Ferron, M. (2012). The contribution of bone to whole-organism physiology. Nature 481, 314-320. doi: 10.1038/nature10763
-
(2012)
Nature
, vol.481
, pp. 314-320
-
-
Karsenty, G.1
Ferron, M.2
-
89
-
-
79960749010
-
Rho-kinase regulates thrombin-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts
-
Kato, K., Otsuka, T., Matsushima-Nishiwaki, R., Natsume, H., Kozawa, O., and Tokuda, H. (2011). Rho-kinase regulates thrombin-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts. Int. J. Mol. Med. 28, 653-658. doi: 10.3892/ijmm.2011.747
-
(2011)
Int. J. Mol. Med
, vol.28
, pp. 653-658
-
-
Kato, K.1
Otsuka, T.2
Matsushima-Nishiwaki, R.3
Natsume, H.4
Kozawa, O.5
Tokuda, H.6
-
90
-
-
80054831375
-
Differential roles of CCN family proteins during osteoblast differentiation: involvement of Smad and MAPK signaling pathways
-
Kawaki, H., Kubota, S., Suzuki, A., Suzuki, M., Kohsaka, K., Hoshi, K., et al. (2011). Differential roles of CCN family proteins during osteoblast differentiation: involvement of Smad and MAPK signaling pathways. Bone 49, 975-989. doi: 10.1016/j.bone.2011.06.033
-
(2011)
Bone
, vol.49
, pp. 975-989
-
-
Kawaki, H.1
Kubota, S.2
Suzuki, A.3
Suzuki, M.4
Kohsaka, K.5
Hoshi, K.6
-
91
-
-
15044357454
-
Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways
-
Kelkar, N., Standen, C. L., and Davis, R. J. (2005). Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol. Cell. Biol. 25, 2733-2743. doi: 10.1128/MCB.25.7.2733-2743.2005
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 2733-2743
-
-
Kelkar, N.1
Standen, C.L.2
Davis, R.J.3
-
92
-
-
23844455632
-
NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade
-
Kendall, S. E., Battelli, C., Irwin, S., Mitchell, J. G., Glackin, C. A., and Verdi, J. M. (2005). NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade. Mol. Cell. Biol. 25, 7711-7724. doi: 10.1128/MCB.25.17.7711-7724.2005
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7711-7724
-
-
Kendall, S.E.1
Battelli, C.2
Irwin, S.3
Mitchell, J.G.4
Glackin, C.A.5
Verdi, J.M.6
-
93
-
-
70350496680
-
Novel effect of biphasic electric current on in vitro osteogenesis and cytokine production in human mesenchymal stromal cells
-
Kim, I. S., Song, J. K., Song, Y. M., Cho, T. H., Lee, T. H., Lim, S. S., et al. (2009). Novel effect of biphasic electric current on in vitro osteogenesis and cytokine production in human mesenchymal stromal cells. Tissue Eng. Part A 15, 2411-2422. doi: 10.1089/ten.tea.2008.0554
-
(2009)
Tissue Eng. Part A
, vol.15
, pp. 2411-2422
-
-
Kim, I.S.1
Song, J.K.2
Song, Y.M.3
Cho, T.H.4
Lee, T.H.5
Lim, S.S.6
-
94
-
-
78049431301
-
Osteogenic responses of human mesenchymal stromal cells to static stretch
-
Kim, I. S., Song, Y. M., and Hwang, S. J. (2010). Osteogenic responses of human mesenchymal stromal cells to static stretch. J. Dent. Res. 89, 1129-1134. doi: 10.1177/0022034510375283
-
(2010)
J. Dent. Res
, vol.89
, pp. 1129-1134
-
-
Kim, I.S.1
Song, Y.M.2
Hwang, S.J.3
-
95
-
-
84903271032
-
Emodin regulates bone remodeling by inhibiting osteoclastogenesis and stimulating osteoblast formation
-
Kim, J. Y., Cheon, Y. H., Kwak, S. C., Baek, J. M., Yoon, K. H., Lee, M. S., et al. (2014). Emodin regulates bone remodeling by inhibiting osteoclastogenesis and stimulating osteoblast formation. J. Bone Miner. Res. 29, 1541-1553. doi: 10.1002/jbmr.2183
-
(2014)
J. Bone Miner. Res
, vol.29
, pp. 1541-1553
-
-
Kim, J.Y.1
Cheon, Y.H.2
Kwak, S.C.3
Baek, J.M.4
Yoon, K.H.5
Lee, M.S.6
-
96
-
-
79952038944
-
15-Deoxy-Delta12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species
-
Kitz, K., Windischhofer, W., Leis, H. J., Huber, E., Kollroser, M., and Malle, E. (2011). 15-Deoxy-Delta12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species. Free Rad. Biol. Med. 50, 854-865. doi: 10.1016/j.freeradbiomed.2010.12.039
-
(2011)
Free Rad. Biol. Med
, vol.50
, pp. 854-865
-
-
Kitz, K.1
Windischhofer, W.2
Leis, H.J.3
Huber, E.4
Kollroser, M.5
Malle, E.6
-
97
-
-
84875838541
-
Mechanosensation and transduction in osteocytes
-
Klein-Nulend, J., Bakker, A. D., Bacabac, R. G., Vatsa, A., and Weinbaum, S. (2013). Mechanosensation and transduction in osteocytes. Bone 54, 182-190. doi: 10.1016/j.bone.2012.10.013
-
(2013)
Bone
, vol.54
, pp. 182-190
-
-
Klein-Nulend, J.1
Bakker, A.D.2
Bacabac, R.G.3
Vatsa, A.4
Weinbaum, S.5
-
98
-
-
84872290003
-
Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase
-
Kocic, J., Santibañez, J. F., Krstic, A., Mojsilovic, S., Ilic, V., and Bugarski, D. (2013). Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase. Int. J. Biochem. Cell Biol. 45, 464-475. doi: 10.1016/j.biocel.2012.11.010
-
(2013)
Int. J. Biochem. Cell Biol
, vol.45
, pp. 464-475
-
-
Kocic, J.1
Santibañez, J.F.2
Krstic, A.3
Mojsilovic, S.4
Ilic, V.5
Bugarski, D.6
-
99
-
-
41349115043
-
Pharmacological properties of SD-282-an alpha-isoform selective inhibitor for p38 MAP kinase
-
Koppelman, B., Webb, H. K., Medicherla, S., Almirez, R., Feng, Y., Chavez, J. C., et al. (2008). Pharmacological properties of SD-282-an alpha-isoform selective inhibitor for p38 MAP kinase. Pharmacology 81, 204-220. doi: 10.1159/000112865
-
(2008)
Pharmacology
, vol.81
, pp. 204-220
-
-
Koppelman, B.1
Webb, H.K.2
Medicherla, S.3
Almirez, R.4
Feng, Y.5
Chavez, J.C.6
-
100
-
-
84959206163
-
Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ-mediated cell death
-
Koyani, C. N., Kitz, K., Rossmann, C., Bernhart, E., Huber, E., Trummer, C., et al. (2016). Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ-mediated cell death. Biochem. Pharmacol. 104, 29-41. doi: 10.1016/j.bcp.2016.01.011
-
(2016)
Biochem. Pharmacol
, vol.104
, pp. 29-41
-
-
Koyani, C.N.1
Kitz, K.2
Rossmann, C.3
Bernhart, E.4
Huber, E.5
Trummer, C.6
-
101
-
-
0033197902
-
Involvement of p38 mitogen-activated protein kinase in basic fibroblast growth factor-induced interleukin-6 synthesis in osteoblasts
-
Kozawa, O., Tokuda, H., Matsuno, H., and Uematsu, T. (1999). Involvement of p38 mitogen-activated protein kinase in basic fibroblast growth factor-induced interleukin-6 synthesis in osteoblasts. J. Cell. Biochem. 74, 479-485
-
(1999)
J. Cell. Biochem
, vol.74
, pp. 479-485
-
-
Kozawa, O.1
Tokuda, H.2
Matsuno, H.3
Uematsu, T.4
-
102
-
-
42049100497
-
Effect of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells
-
Kreke, M. R., Sharp, L. A., Lee, Y. W., and Goldstein, A. S. (2008). Effect of intermittent shear stress on mechanotransductive signaling and osteoblastic differentiation of bone marrow stromal cells. Tissue Eng. Part A 14, 529-537. doi: 10.1089/tea.2007.0068
-
(2008)
Tissue Eng. Part A
, vol.14
, pp. 529-537
-
-
Kreke, M.R.1
Sharp, L.A.2
Lee, Y.W.3
Goldstein, A.S.4
-
103
-
-
42149090508
-
Efficacy of a nitrogen-containing bisphosphonate, minodronate, in conjunction with a p38 mitogen activated protein kinase inhibitor or doxorubicin against malignant bone tumor cells
-
Kubo, T., Shimose, S., Matsuo, T., Sakai, A., and Ochi, M. (2008). Efficacy of a nitrogen-containing bisphosphonate, minodronate, in conjunction with a p38 mitogen activated protein kinase inhibitor or doxorubicin against malignant bone tumor cells. Cancer Chemother. Pharmacol. 62, 111-116. doi: 10.1007/s00280-007-0580-y
-
(2008)
Cancer Chemother. Pharmacol
, vol.62
, pp. 111-116
-
-
Kubo, T.1
Shimose, S.2
Matsuo, T.3
Sakai, A.4
Ochi, M.5
-
104
-
-
0035040946
-
IL-1-and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase
-
Kumar, S., Votta, B. J., Rieman, D. J., Badger, A. M., Gowen, M., and Lee, J. C. (2001). IL-1-and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase. J. Cell. Physiol. 187, 294-303. doi: 10.1002/jcp.1082
-
(2001)
J. Cell. Physiol
, vol.187
, pp. 294-303
-
-
Kumar, S.1
Votta, B.J.2
Rieman, D.J.3
Badger, A.M.4
Gowen, M.5
Lee, J.C.6
-
105
-
-
36048970815
-
Further insights in the mechanisms of interleukin-1beta stimulation of osteoprotegerin in osteoblast-like cells
-
Lambert, C., Oury, C., Dejardin, E., Chariot, A., Piette, J., Malaise, M., et al. (2007). Further insights in the mechanisms of interleukin-1beta stimulation of osteoprotegerin in osteoblast-like cells. J. Bone Miner. Res. 22, 1350-1361. doi: 10.1359/jbmr.070508
-
(2007)
J. Bone Miner. Res
, vol.22
, pp. 1350-1361
-
-
Lambert, C.1
Oury, C.2
Dejardin, E.3
Chariot, A.4
Piette, J.5
Malaise, M.6
-
106
-
-
46249124836
-
Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: roles of extracellular matrix, Shc, and mitogen-activated protein kinase
-
Lee, D. Y., Yeh, C. R., Chang, S. F., Lee, P. L., Chien, S., Cheng, C. K., et al. (2008a). Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: roles of extracellular matrix, Shc, and mitogen-activated protein kinase. J. Bone Miner. Res. 23, 1140-1149. doi: 10.1359/jbmr.080302
-
(2008)
J. Bone Miner. Res
, vol.23
, pp. 1140-1149
-
-
Lee, D.Y.1
Yeh, C.R.2
Chang, S.F.3
Lee, P.L.4
Chien, S.5
Cheng, C.K.6
-
107
-
-
70349974675
-
Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells
-
Lee, H. W., Kim, S. Y., Kim, A. Y., Lee, E. J., Choi, J. Y., and Kim, J. B. (2009). Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells. Stem Cells 27, 2254-2262. doi: 10.1002/stem.144
-
(2009)
Stem Cells
, vol.27
, pp. 2254-2262
-
-
Lee, H.W.1
Kim, S.Y.2
Kim, A.Y.3
Lee, E.J.4
Choi, J.Y.5
Kim, J.B.6
-
108
-
-
47949108989
-
Berberine promotes osteoblast differentiation by Runx2 activation with p38 MAPK
-
Lee, H. W., Suh, J. H., Kim, H. N., Kim, A. Y., Park, S. Y., Shin, C. S., et al. (2008b). Berberine promotes osteoblast differentiation by Runx2 activation with p38 MAPK. J. Bone Miner. Res. 23, 1227-1237. doi: 10.1359/jbmr.080325
-
(2008)
J. Bone Miner. Res
, vol.23
, pp. 1227-1237
-
-
Lee, H.W.1
Suh, J.H.2
Kim, H.N.3
Kim, A.Y.4
Park, S.Y.5
Shin, C.S.6
-
109
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee, J. C., Laydon, J. T., McDonnell, P. C., Gallagher, T. F., Kumar, S., Green, D., et al. (1994). A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372, 739-746. doi: 10.1038/372739a0
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
-
110
-
-
79955802958
-
Costunolide stimulates the function of osteoblastic MC3T3-E1 cells
-
Lee, Y. S., and Choi, E. M. (2011). Costunolide stimulates the function of osteoblastic MC3T3-E1 cells. Int. Immunopharmacol. 11, 712-718. doi: 10.1016/j.intimp.2011.01.018
-
(2011)
Int. Immunopharmacol
, vol.11
, pp. 712-718
-
-
Lee, Y.S.1
Choi, E.M.2
-
111
-
-
0037023713
-
Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C
-
Li, B., Ishii, T., Tan, C. P., Soh, J. W., and Goff, S. P. (2002). Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C. J. Biol. Chem. 277, 12418-12422. doi: 10.1074/jbc.M111443200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 12418-12422
-
-
Li, B.1
Ishii, T.2
Tan, C.P.3
Soh, J.W.4
Goff, S.P.5
-
112
-
-
84937952647
-
Cross-talk between VEGF and BMP-6 pathways accelerates osteogenic differentiation of human adipose-derived stem cells
-
Li, C. J., Madhu, V., Balian, G., Dighe, A. S., and Cui, Q. (2015a). Cross-talk between VEGF and BMP-6 pathways accelerates osteogenic differentiation of human adipose-derived stem cells. J. Cell. Physiol. 230, 2671-2682. doi: 10.1002/jcp.24983
-
(2015)
J. Cell. Physiol
, vol.230
, pp. 2671-2682
-
-
Li, C.J.1
Madhu, V.2
Balian, G.3
Dighe, A.S.4
Cui, Q.5
-
113
-
-
84896496255
-
Hypoxia regulates the proliferation and osteogenic differentiation of human periodontal ligament cells under cyclic tensile stress via mitogen-activated protein kinase pathways
-
Li, L., Han, M. X., Li, S., Xu, Y., and Wang, L. (2014a). Hypoxia regulates the proliferation and osteogenic differentiation of human periodontal ligament cells under cyclic tensile stress via mitogen-activated protein kinase pathways. J. Periodontol. 85, 498-508. doi: 10.1902/jop.2013.130048
-
(2014)
J. Periodontol
, vol.85
, pp. 498-508
-
-
Li, L.1
Han, M.X.2
Li, S.3
Xu, Y.4
Wang, L.5
-
114
-
-
85041722322
-
Regulation of myogenic activation of p38 MAPK by TACE-mediated TNFalpha release
-
Li, Y. P., Niu, A., and Wen, Y. (2014c). Regulation of myogenic activation of p38 MAPK by TACE-mediated TNFalpha release. Front. Cell Dev. Biol. 2:21. doi: 10.3389/fcell.2014.00021
-
(2014)
Front. Cell Dev. Biol
, vol.2
, pp. 21
-
-
Li, Y.P.1
Niu, A.2
Wen, Y.3
-
115
-
-
84928248406
-
Quercetin promotes the osteogenic differentiation of rat mesenchymal stem cells via mitogen-activated protein kinase signaling
-
Li, Y., Wang, J., Chen, G., Feng, S., Wang, P., Zhu, X., et al. (2015b). Quercetin promotes the osteogenic differentiation of rat mesenchymal stem cells via mitogen-activated protein kinase signaling. Exp. Ther. Med. 9, 2072-2080. doi: 10.3892/etm.2015.2388
-
(2015)
Exp. Ther. Med
, vol.9
, pp. 2072-2080
-
-
Li, Y.1
Wang, J.2
Chen, G.3
Feng, S.4
Wang, P.5
Zhu, X.6
-
116
-
-
84927712322
-
17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway
-
Li, Y., Yan, M., Wang, Z., Zheng, Y., Li, J., Ma, S., et al. (2014b). 17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway. Stem Cell Res. Ther. 5, 125. doi: 10.1186/scrt515
-
(2014)
Stem Cell Res. Ther
, vol.5
, pp. 125
-
-
Li, Y.1
Yan, M.2
Wang, Z.3
Zheng, Y.4
Li, J.5
Ma, S.6
-
117
-
-
84891822989
-
Genistein induces oestrogen receptor-alpha gene expression in osteoblasts through the activation of mitogen-activated protein kinases/NF-kappaB/activator protein-1 and promotes cell mineralisation
-
Liao, M. H., Tai, Y. T., Cherng, Y. G., Liu, S. H., Chang, Y. A., Lin, P. I., et al. (2014). Genistein induces oestrogen receptor-alpha gene expression in osteoblasts through the activation of mitogen-activated protein kinases/NF-kappaB/activator protein-1 and promotes cell mineralisation. Br. J. Nutr. 111, 55-63. doi: 10.1017/S0007114513002043
-
(2014)
Br. J. Nutr
, vol.111
, pp. 55-63
-
-
Liao, M.H.1
Tai, Y.T.2
Cherng, Y.G.3
Liu, S.H.4
Chang, Y.A.5
Lin, P.I.6
-
118
-
-
78650934199
-
Role of mitogen-activated protein kinase in osteoblast differentiation
-
Lin, F. H., Chang, J. B., and Brigman, B. E. (2011). Role of mitogen-activated protein kinase in osteoblast differentiation. J. Orthop. Res. 29, 204-210. doi: 10.1002/jor.21222
-
(2011)
J. Orthop. Res
, vol.29
, pp. 204-210
-
-
Lin, F.H.1
Chang, J.B.2
Brigman, B.E.3
-
119
-
-
78349240652
-
Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation
-
Lin, K. L., Chou, C. H., Hsieh, S. C., Hwa, S. Y., Lee, M. T., and Wang, F. F. (2010). Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation. J. Bone Miner. Res. 25, 2489-2503. doi: 10.1002/jbmr.159
-
(2010)
J. Bone Miner. Res
, vol.25
, pp. 2489-2503
-
-
Lin, K.L.1
Chou, C.H.2
Hsieh, S.C.3
Hwa, S.Y.4
Lee, M.T.5
Wang, F.F.6
-
120
-
-
79955631436
-
Activation of c-Jun NH(2)-terminal kinase 1 increases cellular responsiveness to BMP-2 and decreases binding of inhibitory Smad6 to the type 1 BMP receptor
-
Liu, H., Liu, Y., Viggeswarapu, M., Zheng, Z., Titus, L., and Boden, S. D. (2011). Activation of c-Jun NH(2)-terminal kinase 1 increases cellular responsiveness to BMP-2 and decreases binding of inhibitory Smad6 to the type 1 BMP receptor. J. Bone Miner. Res. 26, 1122-1132. doi: 10.1002/jbmr.296
-
(2011)
J. Bone Miner. Res
, vol.26
, pp. 1122-1132
-
-
Liu, H.1
Liu, Y.2
Viggeswarapu, M.3
Zheng, Z.4
Titus, L.5
Boden, S.D.6
-
121
-
-
69649098398
-
Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway
-
Liu, L., Channavajhala, P. L., Rao, V. R., Moutsatsos, I., Wu, L., Zhang, Y., et al. (2009). Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway. Biochim. Biophys. Acta 1794, 1485-1495. doi: 10.1016/j.bbapap.2009.06.016
-
(2009)
Biochim. Biophys. Acta
, vol.1794
, pp. 1485-1495
-
-
Liu, L.1
Channavajhala, P.L.2
Rao, V.R.3
Moutsatsos, I.4
Wu, L.5
Zhang, Y.6
-
122
-
-
0029034251
-
ATF-2 contains a phosphorylation-dependent transcriptional activation domain
-
Livingstone, C., Patel, G., and Jones, N. (1995). ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14, 1785-1797
-
(1995)
EMBO J
, vol.14
, pp. 1785-1797
-
-
Livingstone, C.1
Patel, G.2
Jones, N.3
-
123
-
-
16344385453
-
E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription
-
Lluis, F., Ballestar, E., Suelves, M., Esteller, M., and Munoz-Canoves, P. (2005). E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription. EMBO J. 24, 974-984. doi: 10.1038/sj.emboj.7600528
-
(2005)
EMBO J
, vol.24
, pp. 974-984
-
-
Lluis, F.1
Ballestar, E.2
Suelves, M.3
Esteller, M.4
Munoz-Canoves, P.5
-
124
-
-
30444440735
-
Regulation of skeletal muscle gene expression by p38 MAP kinases
-
Lluis, F., Perdiguero, E., Nebreda, A. R., and Munoz-Canoves, P. (2006). Regulation of skeletal muscle gene expression by p38 MAP kinases. Trends Cell Biol. 16, 36-44. doi: 10.1016/j.tcb.2005.11.002
-
(2006)
Trends Cell Biol
, vol.16
, pp. 36-44
-
-
Lluis, F.1
Perdiguero, E.2
Nebreda, A.R.3
Munoz-Canoves, P.4
-
125
-
-
84255200563
-
Building strong bones: molecular regulation of the osteoblast lineage
-
Long, F. (2012). Building strong bones: molecular regulation of the osteoblast lineage. Nat. Rev. Mol. Cell Biol. 13, 27-38. doi: 10.1038/nrm3254
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 27-38
-
-
Long, F.1
-
126
-
-
84872030260
-
Development of the endochondral skeleton
-
Long, F., and Ornitz, D. M. (2013). Development of the endochondral skeleton. Cold Spring Harb. Perspect. Biol. 5:a008334. doi: 10.1101/cshperspect.a008334
-
(2013)
Cold Spring Harb. Perspect. Biol
, vol.5
-
-
Long, F.1
Ornitz, D.M.2
-
127
-
-
0034913235
-
Differential regulation of Dlx gene expression by a BMP morphogenetic gradient
-
Luo, T., Matsuo-Takasaki, M., Lim, J. H., and Sargent, T. D. (2001). Differential regulation of Dlx gene expression by a BMP morphogenetic gradient. Int. J. Dev. Biol. 45, 681-684
-
(2001)
Int. J. Dev. Biol
, vol.45
, pp. 681-684
-
-
Luo, T.1
Matsuo-Takasaki, M.2
Lim, J.H.3
Sargent, T.D.4
-
128
-
-
33749244468
-
Adiponectin stimulates RANKL and inhibits OPG expression in human osteoblasts through the MAPK signaling pathway
-
Luo, X. H., Guo, L. J., Xie, H., Yuan, L. Q., Wu, X. P., Zhou, H. D., et al. (2006). Adiponectin stimulates RANKL and inhibits OPG expression in human osteoblasts through the MAPK signaling pathway. J. Bone Miner. Res. 21, 1648-1656. doi: 10.1359/jbmr.060707
-
(2006)
J. Bone Miner. Res
, vol.21
, pp. 1648-1656
-
-
Luo, X.H.1
Guo, L.J.2
Xie, H.3
Yuan, L.Q.4
Wu, X.P.5
Zhou, H.D.6
-
129
-
-
23944517324
-
Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway
-
Luo, X. H., Guo, L. J., Yuan, L. Q., Xie, H., Zhou, H. D., Wu, X. P., et al. (2005). Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway. Exp. Cell Res. 309, 99-109. doi: 10.1016/j.yexcr.2005.05.021
-
(2005)
Exp. Cell Res
, vol.309
, pp. 99-109
-
-
Luo, X.H.1
Guo, L.J.2
Yuan, L.Q.3
Xie, H.4
Zhou, H.D.5
Wu, X.P.6
-
130
-
-
68949158625
-
Development of arterial calcification in adiponectin-deficient mice: adiponectin regulates arterial calcification
-
Luo, X. H., Zhao, L. L., Yuan, L. Q., Wang, M., Xie, H., and Liao, E. Y. (2009). Development of arterial calcification in adiponectin-deficient mice: adiponectin regulates arterial calcification. J. Bone Miner. Res. 24, 1461-1468. doi: 10.1359/jbmr.090227
-
(2009)
J. Bone Miner. Res
, vol.24
, pp. 1461-1468
-
-
Luo, X.H.1
Zhao, L.L.2
Yuan, L.Q.3
Wang, M.4
Xie, H.5
Liao, E.Y.6
-
131
-
-
84938375914
-
Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways
-
Ma, J., Ma, Y., Liu, X., Chen, S., Liu, C., Qin, A., et al. (2015). Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways. Biochem. J. 469, 399-408. doi: 10.1042/BJ20150151
-
(2015)
Biochem. J
, vol.469
, pp. 399-408
-
-
Ma, J.1
Ma, Y.2
Liu, X.3
Chen, S.4
Liu, C.5
Qin, A.6
-
132
-
-
75149173154
-
The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors
-
Maekawa, T., Jin, W., and Ishii, S. (2010). The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors. Mol. Cell. Biol. 30, 613-625. doi: 10.1128/MCB.00685-09
-
(2010)
Mol. Cell. Biol
, vol.30
, pp. 613-625
-
-
Maekawa, T.1
Jin, W.2
Ishii, S.3
-
133
-
-
84875074800
-
MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs
-
Mahalingam, C. D., Sampathi, B. R., Sharma, S., Datta, T., Das, V., Abou-Samra, A. B., et al. (2013). MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs. J. Endocrinol. 216, 315-329. doi: 10.1530/JOE-12-0372
-
(2013)
J. Endocrinol
, vol.216
, pp. 315-329
-
-
Mahalingam, C.D.1
Sampathi, B.R.2
Sharma, S.3
Datta, T.4
Das, V.5
Abou-Samra, A.B.6
-
134
-
-
84953357699
-
Estradiol induces osteoprotegerin expression by human dental pulp cells
-
Manokawinchoke, J., Ritprajak, P., Osathanon, T., and Pavasant, P. (2016). Estradiol induces osteoprotegerin expression by human dental pulp cells. Odontology 104, 10-18. doi: 10.1007/s10266-014-0178-x
-
(2016)
Odontology
, vol.104
, pp. 10-18
-
-
Manokawinchoke, J.1
Ritprajak, P.2
Osathanon, T.3
Pavasant, P.4
-
135
-
-
70350536355
-
Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis
-
Matsushita, T., Chan, Y. Y., Kawanami, A., Balmes, G., Landreth, G. E., and Murakami, S. (2009). Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol. Cell. Biol. 29, 5843-5857. doi: 10.1128/MCB.01549-08
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 5843-5857
-
-
Matsushita, T.1
Chan, Y.Y.2
Kawanami, A.3
Balmes, G.4
Landreth, G.E.5
Murakami, S.6
-
136
-
-
33745248460
-
A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis
-
Medicherla, S., Ma, J. Y., Mangadu, R., Jiang, Y., Zhao, J. J., Almirez, R., et al. (2006). A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis. J. Pharmacol. Exp. Ther. 318, 132-141. doi: 10.1124/jpet.105.098020
-
(2006)
J. Pharmacol. Exp. Ther
, vol.318
, pp. 132-141
-
-
Medicherla, S.1
Ma, J.Y.2
Mangadu, R.3
Jiang, Y.4
Zhao, J.J.5
Almirez, R.6
-
137
-
-
21744459448
-
Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells
-
Mehrotra, M., Krane, S. M., Walters, K., and Pilbeam, C. (2004). Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells. J. Cell. Biochem. 93, 741-752. doi: 10.1002/jcb.20138
-
(2004)
J. Cell. Biochem
, vol.93
, pp. 741-752
-
-
Mehrotra, M.1
Krane, S.M.2
Walters, K.3
Pilbeam, C.4
-
138
-
-
84863609091
-
Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism
-
Mieczkowska, A., Basle, M. F., Chappard, D., and Mabilleau, G. (2012). Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism. J. Biol. Chem. 287, 23517-23526. doi: 10.1074/jbc.M111.324814
-
(2012)
J. Biol. Chem
, vol.287
, pp. 23517-23526
-
-
Mieczkowska, A.1
Basle, M.F.2
Chappard, D.3
Mabilleau, G.4
-
139
-
-
48349116048
-
Involvement of Rho-kinase in prostaglandin F2alpha-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts
-
Minamitani, C., Otsuka, T., Takai, S., Matsushima-Nishiwaki, R., Adachi, S., Hanai, Y., et al. (2008). Involvement of Rho-kinase in prostaglandin F2alpha-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts. Mol. Cell. Endocrinol. 291, 27-32. doi: 10.1016/j.mce.2008.05.011
-
(2008)
Mol. Cell. Endocrinol
, vol.291
, pp. 27-32
-
-
Minamitani, C.1
Otsuka, T.2
Takai, S.3
Matsushima-Nishiwaki, R.4
Adachi, S.5
Hanai, Y.6
-
140
-
-
65449165333
-
EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures
-
Minamizaki, T., Yoshiko, Y., Kozai, K., Aubin, J. E., and Maeda, N. (2009). EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures. Bone 44, 1177-1185. doi: 10.1016/j.bone.2009.02.010
-
(2009)
Bone
, vol.44
, pp. 1177-1185
-
-
Minamizaki, T.1
Yoshiko, Y.2
Kozai, K.3
Aubin, J.E.4
Maeda, N.5
-
141
-
-
84870447931
-
Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling
-
Ming, L. G., Chen, K. M., and Xian, C. J. (2013). Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling. J. Cell. Physiol. 228, 513-521. doi: 10.1002/jcp.24158
-
(2013)
J. Cell. Physiol
, vol.228
, pp. 513-521
-
-
Ming, L.G.1
Chen, K.M.2
Xian, C.J.3
-
142
-
-
2942740848
-
Involvement of mitogen-activated protein kinases and protein kinase C in cadmium-induced prostaglandin E2 production in primary mouse osteoblastic cells
-
Miyahara, T., Katoh, T., Watanabe, M., Mikami, Y., Uchida, S., Hosoe, M., et al. (2004). Involvement of mitogen-activated protein kinases and protein kinase C in cadmium-induced prostaglandin E2 production in primary mouse osteoblastic cells. Toxicology 200, 159-167. doi: 10.1016/j.tox.2004.03.014
-
(2004)
Toxicology
, vol.200
, pp. 159-167
-
-
Miyahara, T.1
Katoh, T.2
Watanabe, M.3
Mikami, Y.4
Uchida, S.5
Hosoe, M.6
-
143
-
-
0033120184
-
A BMP-inducible gene, dlx5, regulates osteoblast differentiation and mesoderm induction
-
Miyama, K., Yamada, G., Yamamoto, T. S., Takagi, C., Miyado, K., Sakai, M., et al. (1999). A BMP-inducible gene, dlx5, regulates osteoblast differentiation and mesoderm induction. Dev. Biol. 208, 123-133. doi: 10.1006/dbio.1998.9197
-
(1999)
Dev. Biol
, vol.208
, pp. 123-133
-
-
Miyama, K.1
Yamada, G.2
Yamamoto, T.S.3
Takagi, C.4
Miyado, K.5
Sakai, M.6
-
144
-
-
84903273784
-
Relaxin augments BMP-2-induced osteoblast differentiation and bone formation
-
Moon, J. S., Kim, S. H., Oh, S. H., Jeong, Y. W., Kang, J. H., Park, J. C., et al. (2014). Relaxin augments BMP-2-induced osteoblast differentiation and bone formation. J. Bone Miner. Res. 29, 1586-1596. doi: 10.1002/jbmr.2197
-
(2014)
J. Bone Miner. Res
, vol.29
, pp. 1586-1596
-
-
Moon, J.S.1
Kim, S.H.2
Oh, S.H.3
Jeong, Y.W.4
Kang, J.H.5
Park, J.C.6
-
145
-
-
84936864587
-
In vitro and in vivo bone-forming activity of saururus chinensis extract
-
Moon, S. H., Choi, S. W., Park, S. J., Ryu, S. Y., Hwang, K. S., Kim, C. H., et al. (2015). In vitro and in vivo bone-forming activity of saururus chinensis extract. Phytother. Res. 29, 1073-1080. doi: 10.1002/ptr.5349
-
(2015)
Phytother. Res
, vol.29
, pp. 1073-1080
-
-
Moon, S.H.1
Choi, S.W.2
Park, S.J.3
Ryu, S.Y.4
Hwang, K.S.5
Kim, C.H.6
-
146
-
-
0141619266
-
Estrogen and raloxifene induce apoptosis by activating p38 mitogen-activated protein kinase cascade in synthetic vascular smooth muscle cells
-
Mori-Abe, A., Tsutsumi, S., Takahashi, K., Toya, M., Yoshida, M., Du, B., et al. (2003). Estrogen and raloxifene induce apoptosis by activating p38 mitogen-activated protein kinase cascade in synthetic vascular smooth muscle cells. J. Endocrinol. 178, 417-426. doi: 10.1677/joe.0.1780417
-
(2003)
J. Endocrinol
, vol.178
, pp. 417-426
-
-
Mori-Abe, A.1
Tsutsumi, S.2
Takahashi, K.3
Toya, M.4
Yoshida, M.5
Du, B.6
-
147
-
-
58149235546
-
The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts
-
Nam, T. W., Yoo, C. I., Kim, H. T., Kwon, C. H., Park, J. Y., and Kim, Y. K. (2008). The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts. J. Bone Miner. Metab. 26, 551-560. doi: 10.1007/s00774-008-0864-2
-
(2008)
J. Bone Miner. Metab
, vol.26
, pp. 551-560
-
-
Nam, T.W.1
Yoo, C.I.2
Kim, H.T.3
Kwon, C.H.4
Park, J.Y.5
Kim, Y.K.6
-
148
-
-
12244272655
-
Distinct anabolic response of osteoblast to low-intensity pulsed ultrasound
-
Naruse, K., Miyauchi, A., Itoman, M., and Mikuni-Takagaki, Y. (2003). Distinct anabolic response of osteoblast to low-intensity pulsed ultrasound. J. Bone Miner. Res. 18, 360-369. doi: 10.1359/jbmr.2003.18.2.360
-
(2003)
J. Bone Miner. Res
, vol.18
, pp. 360-369
-
-
Naruse, K.1
Miyauchi, A.2
Itoman, M.3
Mikuni-Takagaki, Y.4
-
149
-
-
0031001097
-
Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element
-
Newberry, E. P., Willis, D., Latifi, T., Boudreaux, J. M., and Towler, D. A. (1997). Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element. Mol. Endocrinol. 11, 1129-1144. doi: 10.1210/mend.11.8.9958
-
(1997)
Mol. Endocrinol
, vol.11
, pp. 1129-1144
-
-
Newberry, E.P.1
Willis, D.2
Latifi, T.3
Boudreaux, J.M.4
Towler, D.A.5
-
150
-
-
85013041894
-
Cold exposure stimulates lipid metabolism, induces inflammatory response in the adipose tissue of mice and promotes the osteogenic differentiation of BMMSCs via the p38 MAPK pathway in vitro
-
Nie, Y., Yan, Z., Yan, W., Xia, Q., and Zhang, Y. (2015). Cold exposure stimulates lipid metabolism, induces inflammatory response in the adipose tissue of mice and promotes the osteogenic differentiation of BMMSCs via the p38 MAPK pathway in vitro. Int. J. Clin. Exp. Pathol. 8, 10875-10886
-
(2015)
Int. J. Clin. Exp. Pathol
, vol.8
, pp. 10875-10886
-
-
Nie, Y.1
Yan, Z.2
Yan, W.3
Xia, Q.4
Zhang, Y.5
-
151
-
-
80054912384
-
Asperosaponin I., a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway
-
Niu, Y., Li, Y., Huang, H., Kong, X., Zhang, R., Liu, L., et al. (2011). Asperosaponin, V. I., a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother. Res. 25, 1700-1706. doi: 10.1002/ptr.3414
-
(2011)
Phytother. Res
, vol.25
, pp. 1700-1706
-
-
Niu, Y.1
Li, Y.2
Huang, H.3
Kong, X.4
Zhang, R.5
Liu, L.6
-
152
-
-
17544395678
-
Activation of p38 and Smads mediates BMP-2 effects on human trabecular bone-derived osteoblasts
-
Noth, U., Tuli, R., Seghatoleslami, R., Howard, M., Shah, A., Hall, D. J., et al. (2003). Activation of p38 and Smads mediates BMP-2 effects on human trabecular bone-derived osteoblasts. Exp. Cell Res. 291, 201-211. doi: 10.1016/S0014-4827(03)00386-0
-
(2003)
Exp. Cell Res
, vol.291
, pp. 201-211
-
-
Noth, U.1
Tuli, R.2
Seghatoleslami, R.3
Howard, M.4
Shah, A.5
Hall, D.J.6
-
153
-
-
84874040170
-
Osteocyte control of osteoclastogenesis
-
O'Brien, C. A., Nakashima, T., and Takayanagi, H. (2013). Osteocyte control of osteoclastogenesis. Bone 54, 258-263. doi: 10.1016/j.bone.2012.08.121
-
(2013)
Bone
, vol.54
, pp. 258-263
-
-
O'Brien, C.A.1
Nakashima, T.2
Takayanagi, H.3
-
154
-
-
84879629285
-
Loss of p38delta mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth
-
O'Callaghan, C., Fanning, L. J., Houston, A., and Barry, O. P. (2013). Loss of p38delta mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth. Int. J. Oncol. 43, 405-415. doi: 10.3892/ijo.2013.1968
-
(2013)
Int. J. Oncol
, vol.43
, pp. 405-415
-
-
O'Callaghan, C.1
Fanning, L.J.2
Houston, A.3
Barry, O.P.4
-
155
-
-
84893040697
-
The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases
-
Odagiri, H., Kadomatsu, T., Endo, M., Masuda, T., Morioka, M. S., Fukuhara, S., et al. (2014). The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases. Sci Signal 7:ra7. doi: 10.1126/scisignal.2004612
-
(2014)
Sci Signal
, vol.7
-
-
Odagiri, H.1
Kadomatsu, T.2
Endo, M.3
Masuda, T.4
Morioka, M.S.5
Fukuhara, S.6
-
156
-
-
84863129183
-
PlexinA2 mediates osteoblast differentiation via regulation of Runx2
-
Oh, J. E., Kim, H. J., Kim, W. S., Lee, Z. H., Ryoo, H. M., Hwang, S. J., et al. (2012). PlexinA2 mediates osteoblast differentiation via regulation of Runx2. J. Bone Miner. Res. 27, 552-562. doi: 10.1002/jbmr.1471
-
(2012)
J. Bone Miner. Res
, vol.27
, pp. 552-562
-
-
Oh, J.E.1
Kim, H.J.2
Kim, W.S.3
Lee, Z.H.4
Ryoo, H.M.5
Hwang, S.J.6
-
157
-
-
77957801598
-
p38 regulates expression of osteoblast-specific genes by phosphorylation of osterix
-
Ortuno, M. J., Ruiz-Gaspa, S., Rodriguez-Carballo, E., Susperregui, A. R., Bartrons, R., Rosa, J. L., et al. (2010). p38 regulates expression of osteoblast-specific genes by phosphorylation of osterix. J. Biol. Chem. 285, 31985-31994. doi: 10.1074/jbc.M110.123612
-
(2010)
J. Biol. Chem
, vol.285
, pp. 31985-31994
-
-
Ortuno, M.J.1
Ruiz-Gaspa, S.2
Rodriguez-Carballo, E.3
Susperregui, A.R.4
Bartrons, R.5
Rosa, J.L.6
-
158
-
-
84875024063
-
Osterix induces Col1a1 gene expression through binding to Sp1 sites in the bone enhancer and proximal promoter regions
-
Ortuno, M. J., Susperregui, A. R., Artigas, N., Rosa, J. L., and Ventura, F. (2013). Osterix induces Col1a1 gene expression through binding to Sp1 sites in the bone enhancer and proximal promoter regions. Bone 52, 548-556. doi: 10.1016/j.bone.2012.11.007
-
(2013)
Bone
, vol.52
, pp. 548-556
-
-
Ortuno, M.J.1
Susperregui, A.R.2
Artigas, N.3
Rosa, J.L.4
Ventura, F.5
-
159
-
-
68849117424
-
Identification of differentially expressed genes between osteoblasts and osteocytes
-
Paic, F., Igwe, J. C., Nori, R., Kronenberg, M. S., Franceschetti, T., Harrington, P., et al. (2009). Identification of differentially expressed genes between osteoblasts and osteocytes. Bone 45, 682-692. doi: 10.1016/j.bone.2009.06.010
-
(2009)
Bone
, vol.45
, pp. 682-692
-
-
Paic, F.1
Igwe, J.C.2
Nori, R.3
Kronenberg, M.S.4
Franceschetti, T.5
Harrington, P.6
-
160
-
-
33846290960
-
Phosphodiesterase 4 inhibitor regulates the TRANCE/OPG ratio via COX-2 expression in a manner similar to PTH in osteoblasts
-
Park, H., Young Lee, S., Lee, D. S., and Yim, M. (2007). Phosphodiesterase 4 inhibitor regulates the TRANCE/OPG ratio via COX-2 expression in a manner similar to PTH in osteoblasts. Biochem. Biophys. Res. Commun. 354, 178-183. doi: 10.1016/j.bbrc.2006.12.174
-
(2007)
Biochem. Biophys. Res. Commun
, vol.354
, pp. 178-183
-
-
Park, H.1
Young Lee, S.2
Lee, D.S.3
Yim, M.4
-
161
-
-
74549144553
-
Molecular and mechano-biology of collagen gel contraction mediated by human MG-63 cells: involvement of specific intracellular signaling pathways and the cytoskeleton
-
Parreno, J., and Hart, D. A. (2009). Molecular and mechano-biology of collagen gel contraction mediated by human MG-63 cells: involvement of specific intracellular signaling pathways and the cytoskeleton. Biochem. Cell Biol. 87, 895-904. doi: 10.1139/O09-052
-
(2009)
Biochem. Cell Biol
, vol.87
, pp. 895-904
-
-
Parreno, J.1
Hart, D.A.2
-
162
-
-
2542469918
-
p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts
-
Patil, C., Zhu, X., Rossa, C. Jr., Kim, Y. J., and Kirkwood, K. L. (2004). p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts. Immunol. Invest. 33, 213-233. doi: 10.1081/IMM-120034231
-
(2004)
Immunol. Invest
, vol.33
, pp. 213-233
-
-
Patil, C.1
Zhu, X.2
Rossa, C.3
Kim, Y.J.4
Kirkwood, K.L.5
-
163
-
-
84880583883
-
Angiogenesis and intramembranous osteogenesis
-
Percival, C. J., and Richtsmeier, J. T. (2013). Angiogenesis and intramembranous osteogenesis. Dev. Dyn. 242, 909-922. doi: 10.1002/dvdy.23992
-
(2013)
Dev. Dyn
, vol.242
, pp. 909-922
-
-
Percival, C.J.1
Richtsmeier, J.T.2
-
164
-
-
0034162714
-
Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells
-
Puri, P. L., Wu, Z., Zhang, P., Wood, L. D., Bhakta, K. S., Han, J., et al. (2000). Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev. 14, 574-584
-
(2000)
Genes Dev
, vol.14
, pp. 574-584
-
-
Puri, P.L.1
Wu, Z.2
Zhang, P.3
Wood, L.D.4
Bhakta, K.S.5
Han, J.6
-
165
-
-
1942533517
-
BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways
-
Qi, X., Li, T. G., Hao, J., Hu, J., Wang, J., Simmons, H., et al. (2004). BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc. Natl. Acad. Sci. U.S.A. 101, 6027-6032. doi: 10.1073/pnas.0401367101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 6027-6032
-
-
Qi, X.1
Li, T.G.2
Hao, J.3
Hu, J.4
Wang, J.5
Simmons, H.6
-
166
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
Raingeaud, J., Gupta, S., Rogers, J. S., Dickens, M., Han, J., Ulevitch, R. J., et al. (1995). Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426. doi: 10.1074/jbc.270.13.7420
-
(1995)
J. Biol. Chem
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
-
167
-
-
74449083698
-
Differential activation of p38MAPK isoforms by MKK6 and MKK3
-
Remy, G., Risco, A. M., Inesta-Vaquera, F. A., Gonzalez-Teran, B., Sabio, G., Davis, R. J., et al. (2010). Differential activation of p38MAPK isoforms by MKK6 and MKK3. Cell. Signal. 22, 660-667. doi: 10.1016/j.cellsig.2009.11.020
-
(2010)
Cell. Signal
, vol.22
, pp. 660-667
-
-
Remy, G.1
Risco, A.M.2
Inesta-Vaquera, F.A.3
Gonzalez-Teran, B.4
Sabio, G.5
Davis, R.J.6
-
168
-
-
34250029687
-
Evidences for a role of p38 MAP kinase in the stimulation of alkaline phosphatase and matrix mineralization induced by parathyroid hormone in osteoblastic cells
-
Rey, A., Manen, D., Rizzoli, R., Ferrari, S. L., and Caverzasio, J. (2007). Evidences for a role of p38 MAP kinase in the stimulation of alkaline phosphatase and matrix mineralization induced by parathyroid hormone in osteoblastic cells. Bone 41, 59-67. doi: 10.1016/j.bone.2007.02.031
-
(2007)
Bone
, vol.41
, pp. 59-67
-
-
Rey, A.1
Manen, D.2
Rizzoli, R.3
Ferrari, S.L.4
Caverzasio, J.5
-
169
-
-
77956461991
-
Osteocyte: the unrecognized side of bone tissue
-
Rochefort, G. Y., Pallu, S., and Benhamou, C. L. (2010). Osteocyte: the unrecognized side of bone tissue. Osteoporos. Int. 21, 1457-1469. doi: 10.1007/s00198-010-1194-5
-
(2010)
Osteoporos. Int
, vol.21
, pp. 1457-1469
-
-
Rochefort, G.Y.1
Pallu, S.2
Benhamou, C.L.3
-
170
-
-
84931307562
-
p38alpha function in osteoblasts influences adipose tissue homeostasis
-
Rodriguez-Carballo, E., Gamez, B., Mendez-Lucas, A., Sanchez-Freutrie, M., Zorzano, A., Bartrons, R., et al. (2015). p38alpha function in osteoblasts influences adipose tissue homeostasis. FASEB J. 29, 1414-1425. doi: 10.1096/fj.14-261891
-
(2015)
FASEB J
, vol.29
, pp. 1414-1425
-
-
Rodriguez-Carballo, E.1
Gamez, B.2
Mendez-Lucas, A.3
Sanchez-Freutrie, M.4
Zorzano, A.5
Bartrons, R.6
-
171
-
-
84904092797
-
The p38alpha MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice
-
Rodriguez-Carballo, E., Gamez, B., Sedo-Cabezon, L., Sanchez-Feutrie, M., Zorzano, A., Manzanares-Cespedes, C., et al. (2014). The p38alpha MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice. PLoS ONE 9:e102032. doi: 10.1371/journal.pone.0102032
-
(2014)
PLoS ONE
, vol.9
-
-
Rodriguez-Carballo, E.1
Gamez, B.2
Sedo-Cabezon, L.3
Sanchez-Feutrie, M.4
Zorzano, A.5
Manzanares-Cespedes, C.6
-
172
-
-
79953046941
-
Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways
-
Rodriguez-Carballo, E., Ulsamer, A., Susperregui, A. R., Manzanares-Cespedes, C., Sanchez-Garcia, E., Bartrons, R., et al. (2011). Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways. J. Bone Miner. Res. 26, 718-729. doi: 10.1002/jbmr.260
-
(2011)
J. Bone Miner. Res
, vol.26
, pp. 718-729
-
-
Rodriguez-Carballo, E.1
Ulsamer, A.2
Susperregui, A.R.3
Manzanares-Cespedes, C.4
Sanchez-Garcia, E.5
Bartrons, R.6
-
173
-
-
0030734010
-
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
Rousseau, S., Houle, F., Landry, J., and Huot, J. (1997). p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15, 2169-2177. doi: 10.1038/sj.onc.1201380
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rousseau, S.1
Houle, F.2
Landry, J.3
Huot, J.4
-
174
-
-
77954763320
-
Migration of human umbilical cord blood mesenchymal stem cells mediated by stromal cell-derived factor-1/CXCR4 axis via Akt, ERK, and p38 signal transduction pathways
-
Ryu, C. H., Park, S. A., Kim, S. M., Lim, J. Y., Jeong, C. H., Jun, J. A., et al. (2010). Migration of human umbilical cord blood mesenchymal stem cells mediated by stromal cell-derived factor-1/CXCR4 axis via Akt, ERK, and p38 signal transduction pathways. Biochem. Biophys. Res. Commun. 398, 105-110. doi: 10.1016/j.bbrc.2010.06.043
-
(2010)
Biochem. Biophys. Res. Commun
, vol.398
, pp. 105-110
-
-
Ryu, C.H.1
Park, S.A.2
Kim, S.M.3
Lim, J.Y.4
Jeong, C.H.5
Jun, J.A.6
-
175
-
-
20244365497
-
p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
-
Sabio, G., Arthur, J. S., Kuma, Y., Peggie, M., Carr, J., Murray-Tait, V., et al. (2005). p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. EMBO J. 24, 1134-1145. doi: 10.1038/sj.emboj.7600578
-
(2005)
EMBO J
, vol.24
, pp. 1134-1145
-
-
Sabio, G.1
Arthur, J.S.2
Kuma, Y.3
Peggie, M.4
Carr, J.5
Murray-Tait, V.6
-
176
-
-
84889882595
-
Effects of phytoestrogens and other plant-derived compounds on mesenchymal stem cells, bone maintenance and regeneration
-
Schilling, T., Ebert, R., Raaijmakers, N., Schütze, N., and Jakob, F. (2014). Effects of phytoestrogens and other plant-derived compounds on mesenchymal stem cells, bone maintenance and regeneration. J. Steroid Biochem. Mol. Biol. 139, 252-261. doi: 10.1016/j.jsbmb.2012.12.006
-
(2014)
J. Steroid Biochem. Mol. Biol
, vol.139
, pp. 252-261
-
-
Schilling, T.1
Ebert, R.2
Raaijmakers, N.3
Schütze, N.4
Jakob, F.5
-
177
-
-
66349138173
-
p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice
-
Schindler, E. M., Hindes, A., Gribben, E. L., Burns, C. J., Yin, Y., Lin, M. H., et al. (2009). p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer Res. 69, 4648-4655. doi: 10.1158/0008-5472.CAN-08-4455
-
(2009)
Cancer Res
, vol.69
, pp. 4648-4655
-
-
Schindler, E.M.1
Hindes, A.2
Gribben, E.L.3
Burns, C.J.4
Yin, Y.5
Lin, M.H.6
-
178
-
-
84899092275
-
CD99 drives terminal differentiation of osteosarcoma cells by acting as a spatial regulator of ERK 1/2
-
Sciandra, M., Marino, M. T., Manara, M. C., Guerzoni, C., Grano, M., Oranger, A., et al. (2014). CD99 drives terminal differentiation of osteosarcoma cells by acting as a spatial regulator of ERK 1/2. J. Bone Miner. Res. 29, 1295-1309. doi: 10.1002/jbmr.2141
-
(2014)
J. Bone Miner. Res
, vol.29
, pp. 1295-1309
-
-
Sciandra, M.1
Marino, M.T.2
Manara, M.C.3
Guerzoni, C.4
Grano, M.5
Oranger, A.6
-
179
-
-
2442489944
-
Transforming growth factor-beta 1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the Smad and MAPK signaling pathways and their components, Smad2 and Runx2
-
Selvamurugan, N., Kwok, S., Alliston, T., Reiss, M., and Partridge, N. C. (2004). Transforming growth factor-beta 1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the Smad and MAPK signaling pathways and their components, Smad2 and Runx2. J. Biol. Chem. 279, 19327-19334. doi: 10.1074/jbc.M314048200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 19327-19334
-
-
Selvamurugan, N.1
Kwok, S.2
Alliston, T.3
Reiss, M.4
Partridge, N.C.5
-
180
-
-
84880036137
-
Cell cycle and apoptosis regulatory protein (CARP)-1 is expressed in osteoblasts and regulated by PTH
-
Sharma, S., Mahalingam, C. D., Das, V., Jamal, S., Levi, E., Rishi, A. K., et al. (2013). Cell cycle and apoptosis regulatory protein (CARP)-1 is expressed in osteoblasts and regulated by PTH. Biochem. Biophys. Res. Commun. 436, 607-612. doi: 10.1016/j.bbrc.2013.05.136
-
(2013)
Biochem. Biophys. Res. Commun
, vol.436
, pp. 607-612
-
-
Sharma, S.1
Mahalingam, C.D.2
Das, V.3
Jamal, S.4
Levi, E.5
Rishi, A.K.6
-
181
-
-
84884244932
-
Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide
-
Siebel, A., Cubillos-Rojas, M., Santos, R. C., Schneider, T., Bonan, C. D., Bartrons, R., et al. (2013). Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide. PLoS ONE 8:e75523. doi: 10.1371/journal.pone.0075523
-
(2013)
PLoS ONE
, vol.8
-
-
Siebel, A.1
Cubillos-Rojas, M.2
Santos, R.C.3
Schneider, T.4
Bonan, C.D.5
Bartrons, R.6
-
182
-
-
0037405123
-
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity
-
Sierra, J., Villagra, A., Paredes, R., Cruzat, F., Gutierrez, S., Javed, A., et al. (2003). Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity. Mol. Cell. Biol. 23, 3339-3351. doi: 10.1128/MCB.23.9.3339-3351.2003
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 3339-3351
-
-
Sierra, J.1
Villagra, A.2
Paredes, R.3
Cruzat, F.4
Gutierrez, S.5
Javed, A.6
-
183
-
-
3042763342
-
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
-
Simone, C., Forcales, S. V., Hill, D. A., Imbalzano, A. N., Latella, L., and Puri, P. L. (2004). p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat. Genet. 36, 738-743. doi: 10.1038/ng1378
-
(2004)
Nat. Genet
, vol.36
, pp. 738-743
-
-
Simone, C.1
Forcales, S.V.2
Hill, D.A.3
Imbalzano, A.N.4
Latella, L.5
Puri, P.L.6
-
184
-
-
0031005576
-
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density
-
Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M. S., Luthy, R., et al. (1997). Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89, 309-319. doi: 10.1016/S0092-8674(00)80209-3
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.S.5
Luthy, R.6
-
185
-
-
56749174709
-
Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells
-
Soda, A., Ikehara, T., Kinouchi, Y., and Yoshizaki, K. (2008). Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells. J. Med. Invest. 55, 267-278. doi: 10.2152/jmi.55.267
-
(2008)
J. Med. Invest
, vol.55
, pp. 267-278
-
-
Soda, A.1
Ikehara, T.2
Kinouchi, Y.3
Yoshizaki, K.4
-
186
-
-
84944346066
-
Silica nanoparticles inhibit brown adipocyte differentiation via regulation of p38 phosphorylation
-
Son, M. J., Kim, W. K., Kwak, M., Oh, K. J., Chang, W. S., Min, J. K., et al. (2015). Silica nanoparticles inhibit brown adipocyte differentiation via regulation of p38 phosphorylation. Nanotechnology 26:435101. doi: 10.1088/0957-4484/26/43/435101
-
(2015)
Nanotechnology
, vol.26
-
-
Son, M.J.1
Kim, W.K.2
Kwak, M.3
Oh, K.J.4
Chang, W.S.5
Min, J.K.6
-
187
-
-
53349164136
-
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
-
Sorrentino, A., Thakur, N., Grimsby, S., Marcusson, A., von Bulow, V., Schuster, N., et al. (2008). The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat. Cell Biol. 10, 1199-1207. doi: 10.1038/ncb1780
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 1199-1207
-
-
Sorrentino, A.1
Thakur, N.2
Grimsby, S.3
Marcusson, A.4
von Bulow, V.5
Schuster, N.6
-
188
-
-
58249087541
-
Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis
-
Sumara, G., Formentini, I., Collins, S., Sumara, I., Windak, R., Bodenmiller, B., et al. (2009). Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis. Cell 136, 235-248. doi: 10.1016/j.cell.2008.11.018
-
(2009)
Cell
, vol.136
, pp. 235-248
-
-
Sumara, G.1
Formentini, I.2
Collins, S.3
Sumara, I.4
Windak, R.5
Bodenmiller, B.6
-
189
-
-
0036138735
-
Evidence for a role of p38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation
-
Suzuki, A., Guicheux, J., Palmer, G., Miura, Y., Oiso, Y., Bonjour, J. P., et al. (2002). Evidence for a role of p38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation. Bone 30, 91-98. doi: 10.1016/S8756-3282(01)00660-3
-
(2002)
Bone
, vol.30
, pp. 91-98
-
-
Suzuki, A.1
Guicheux, J.2
Palmer, G.3
Miura, Y.4
Oiso, Y.5
Bonjour, J.P.6
-
190
-
-
0033304803
-
Regulation of alkaline phosphatase activity by p38 MAP kinase in response to activation of Gi protein-coupled receptors by epinephrine in osteoblast-like cells
-
Suzuki, A., Palmer, G., Bonjour, J. P., and Caverzasio, J. (1999). Regulation of alkaline phosphatase activity by p38 MAP kinase in response to activation of Gi protein-coupled receptors by epinephrine in osteoblast-like cells. Endocrinology 140, 3177-3182. doi: 10.1210/en.140.7.3177
-
(1999)
Endocrinology
, vol.140
, pp. 3177-3182
-
-
Suzuki, A.1
Palmer, G.2
Bonjour, J.P.3
Caverzasio, J.4
-
191
-
-
84896492200
-
Cyclic tensile force up-regulates BMP-2 expression through MAP kinase and COX-2/PGE2 signaling pathways in human periodontal ligament cells
-
Suzuki, R., Nemoto, E., and Shimauchi, H. (2014). Cyclic tensile force up-regulates BMP-2 expression through MAP kinase and COX-2/PGE2 signaling pathways in human periodontal ligament cells. Exp. Cell Res. 323, 232-241. doi: 10.1016/j.yexcr.2014.02.013
-
(2014)
Exp. Cell Res
, vol.323
, pp. 232-241
-
-
Suzuki, R.1
Nemoto, E.2
Shimauchi, H.3
-
192
-
-
84863131227
-
CCN3 increases BMP-4 expression and bone mineralization in osteoblasts
-
Tan, T. W., Huang, Y. L., Chang, J. T., Lin, J. J., Fong, Y. C., Kuo, C. C., et al. (2012). CCN3 increases BMP-4 expression and bone mineralization in osteoblasts. J. Cell. Physiol. 227, 2531-2541. doi: 10.1002/jcp.22991
-
(2012)
J. Cell. Physiol
, vol.227
, pp. 2531-2541
-
-
Tan, T.W.1
Huang, Y.L.2
Chang, J.T.3
Lin, J.J.4
Fong, Y.C.5
Kuo, C.C.6
-
193
-
-
84918813324
-
Knockdown of Sec8 enhances the binding affinity of c-Jun N-terminal kinase (JNK)-interacting protein 4 for mitogen-activated protein kinase kinase 4 (MKK4) and suppresses the phosphorylation of MKK4, p38, and JNK, thereby inhibiting apoptosis
-
Tanaka, T., Iino, M., and Goto, K. (2014). Knockdown of Sec8 enhances the binding affinity of c-Jun N-terminal kinase (JNK)-interacting protein 4 for mitogen-activated protein kinase kinase 4 (MKK4) and suppresses the phosphorylation of MKK4, p38, and JNK, thereby inhibiting apoptosis. FEBS J. 281, 5237-5250. doi: 10.1111/febs.13063
-
(2014)
FEBS J
, vol.281
, pp. 5237-5250
-
-
Tanaka, T.1
Iino, M.2
Goto, K.3
-
194
-
-
37549069399
-
Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts
-
Tang, C. H., Yang, R. S., Chien, M. Y., Chen, C. C., and Fu, W. M. (2008). Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts. Eur. J. Pharmacol. 579, 40-49. doi: 10.1016/j.ejphar.2007.10.013
-
(2008)
Eur. J. Pharmacol
, vol.579
, pp. 40-49
-
-
Tang, C.H.1
Yang, R.S.2
Chien, M.Y.3
Chen, C.C.4
Fu, W.M.5
-
195
-
-
84859179324
-
Differentiation of osteoprogenitor cells is induced by high-frequency pulsed electromagnetic fields
-
Teven, C. M., Greives, M., Natale, R. B., Su, Y., Luo, Q., He, B. C., et al. (2012). Differentiation of osteoprogenitor cells is induced by high-frequency pulsed electromagnetic fields. J. Craniofac. Surg. 23, 586-593. doi: 10.1097/SCS.0b013e31824cd6de
-
(2012)
J. Craniofac. Surg
, vol.23
, pp. 586-593
-
-
Teven, C.M.1
Greives, M.2
Natale, R.B.3
Su, Y.4
Luo, Q.5
He, B.C.6
-
196
-
-
84865628977
-
The p38alpha MAPK positively regulates osteoblast function and postnatal bone acquisition
-
Thouverey, C., and Caverzasio, J. (2012). The p38alpha MAPK positively regulates osteoblast function and postnatal bone acquisition. Cell. Mol. Life Sci. 69, 3115-3125. doi: 10.1007/s00018-012-0983-8
-
(2012)
Cell. Mol. Life Sci
, vol.69
, pp. 3115-3125
-
-
Thouverey, C.1
Caverzasio, J.2
-
197
-
-
84986298979
-
Focus on the p38 MAPK signaling pathway in bone development and maintenance
-
Thouverey, C., and Caverzasio, J. (2015a). Focus on the p38 MAPK signaling pathway in bone development and maintenance. Bonekey Rep. 4, 711. doi: 10.1038/bonekey.2015.80
-
(2015)
Bonekey Rep
, vol.4
, pp. 711
-
-
Thouverey, C.1
Caverzasio, J.2
-
198
-
-
84968752808
-
Suppression of p38a MAPK signaling in osteoblast lineage cells impairs bone anabolic action of parathyroid hormone
-
[Epub ahead of print]
-
Thouverey, C., and Caverzasio, J. (2015b). Suppression of p38a MAPK signaling in osteoblast lineage cells impairs bone anabolic action of parathyroid hormone. J. Bone Miner. Res. doi: 10.1002/jbmr.2762. [Epub ahead of print]
-
(2015)
J. Bone Miner. Res
-
-
Thouverey, C.1
Caverzasio, J.2
-
199
-
-
0038172625
-
Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts
-
Tokuda, H., Hatakeyama, D., Akamatsu, S., Tanabe, K., Yoshida, M., Shibata, T., et al. (2003). Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts. Arch. Biochem. Biophys. 415, 117-125. doi: 10.1016/S0003-9861(03)00225-X
-
(2003)
Arch. Biochem. Biophys
, vol.415
, pp. 117-125
-
-
Tokuda, H.1
Hatakeyama, D.2
Akamatsu, S.3
Tanabe, K.4
Yoshida, M.5
Shibata, T.6
-
200
-
-
0034838274
-
p38 mitogen-activated protein (MAP) kinase but not p44/p42 MAP kinase is involved in prostaglandin E1-induced vascular endothelial growth factor synthesis in osteoblasts
-
Tokuda, H., Kozawa, O., Miwa, M., and Uematsu, T. (2001). p38 mitogen-activated protein (MAP) kinase but not p44/p42 MAP kinase is involved in prostaglandin E1-induced vascular endothelial growth factor synthesis in osteoblasts. J. Endocrinol. 170, 629-638. doi: 10.1677/joe.0.1700629
-
(2001)
J. Endocrinol
, vol.170
, pp. 629-638
-
-
Tokuda, H.1
Kozawa, O.2
Miwa, M.3
Uematsu, T.4
-
201
-
-
84867376512
-
Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38alpha/beta MAPK
-
Troy, A., Cadwallader, A. B., Fedorov, Y., Tyner, K., Tanaka, K. K., and Olwin, B. B. (2012). Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38alpha/beta MAPK. Cell Stem Cell 11, 541-553. doi: 10.1016/j.stem.2012.05.025
-
(2012)
Cell Stem Cell
, vol.11
, pp. 541-553
-
-
Troy, A.1
Cadwallader, A.B.2
Fedorov, Y.3
Tyner, K.4
Tanaka, K.K.5
Olwin, B.B.6
-
202
-
-
84864339834
-
Bisphosphonate-and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2
-
Tsubaki, M., Satou, T., Itoh, T., Imano, M., Yanae, M., Kato, C., et al. (2012). Bisphosphonate-and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2. Mol. Cell. Endocrinol. 361, 219-231. doi: 10.1016/j.mce.2012.05.002
-
(2012)
Mol. Cell. Endocrinol
, vol.361
, pp. 219-231
-
-
Tsubaki, M.1
Satou, T.2
Itoh, T.3
Imano, M.4
Yanae, M.5
Kato, C.6
-
203
-
-
42949101521
-
BMP-2 induces Osterix expression through up-regulation of Dlx5 and its phosphorylation by p38
-
Ulsamer, A., Ortuño, M. J., Ruiz, S., Susperregui, A. R., Osses, N., Rosa, J. L., et al. (2008). BMP-2 induces Osterix expression through up-regulation of Dlx5 and its phosphorylation by p38. J. Biol. Chem. 283, 3816-3826. doi: 10.1074/jbc.M704724200
-
(2008)
J. Biol. Chem
, vol.283
, pp. 3816-3826
-
-
Ulsamer, A.1
Ortuño, M.J.2
Ruiz, S.3
Susperregui, A.R.4
Osses, N.5
Rosa, J.L.6
-
204
-
-
21344450560
-
SOST/sclerostin, an osteocyte-derived negative regulator of bone formation
-
van Bezooijen, R. L., ten Dijke, P., Papapoulos, S. E., and Lowik, C. W. (2005). SOST/sclerostin, an osteocyte-derived negative regulator of bone formation. Cytokine Growth Factor Rev. 16, 319-327. doi: 10.1016/j.cytogfr.2005.02.005
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 319-327
-
-
van Bezooijen, R.L.1
ten Dijke, P.2
Papapoulos, S.E.3
Lowik, C.W.4
-
205
-
-
0037005903
-
Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2
-
Viñals, F., López-Rovira, T., Rosa, J. L., and Ventura, F. (2002). Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2. FEBS Lett. 510, 99-104. doi: 10.1016/S0014-5793(01)03236-7
-
(2002)
FEBS Lett
, vol.510
, pp. 99-104
-
-
Viñals, F.1
López-Rovira, T.2
Rosa, J.L.3
Ventura, F.4
-
206
-
-
0035937158
-
The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase alpha Implications for signal/response profiles of MAP kinase pathways
-
Waas, W. F., Lo, H. H., and Dalby, K. N. (2001). The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase alpha. Implications for signal/response profiles of MAP kinase pathways. J. Biol. Chem. 276, 5676-5684. doi: 10.1074/jbc.M008787200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 5676-5684
-
-
Waas, W.F.1
Lo, H.H.2
Dalby, K.N.3
-
207
-
-
84915746471
-
The effect of neuropeptide Y on brown-like adipocyte's differentiation and activation
-
Wan, Y., Xue, R., Wang, Y., Zhang, Q., Huang, S., Wu, W., et al. (2015). The effect of neuropeptide Y on brown-like adipocyte's differentiation and activation. Peptides 63, 126-133. doi: 10.1016/j.peptides.2014.10.018
-
(2015)
Peptides
, vol.63
, pp. 126-133
-
-
Wan, Y.1
Xue, R.2
Wang, Y.3
Zhang, Q.4
Huang, S.5
Wu, W.6
-
208
-
-
84861543050
-
Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways
-
Wanachewin, O., Boonmaleerat, K., Pothacharoen, P., Reutrakul, V., and Kongtawelert, P. (2012). Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways. BMC Complement. Altern. Med. 12:71. doi: 10.1186/1472-6882-12-71
-
(2012)
BMC Complement. Altern. Med
, vol.12
, pp. 71
-
-
Wanachewin, O.1
Boonmaleerat, K.2
Pothacharoen, P.3
Reutrakul, V.4
Kongtawelert, P.5
-
209
-
-
84865145898
-
Involvement of p38MAPK/NF-kappaB signaling pathways in osteoblasts differentiation in response to mechanical stretch
-
Wang, L., Li, J. Y., Zhang, X. Z., Liu, L., Wan, Z. M., Li, R. X., et al. (2012). Involvement of p38MAPK/NF-kappaB signaling pathways in osteoblasts differentiation in response to mechanical stretch. Ann. Biomed. Eng. 40, 1884-1894. doi: 10.1007/s10439-012-0548-x
-
(2012)
Ann. Biomed. Eng
, vol.40
, pp. 1884-1894
-
-
Wang, L.1
Li, J.Y.2
Zhang, X.Z.3
Liu, L.4
Wan, Z.M.5
Li, R.X.6
-
210
-
-
0037497392
-
Mechanism of simvastatin on induction of heat shock protein in osteoblasts
-
Wang, X., Tokuda, H., Hatakeyama, D., Hirade, K., Niwa, M., Ito, H., et al. (2003). Mechanism of simvastatin on induction of heat shock protein in osteoblasts. Arch. Biochem. Biophys. 415, 6-13. doi: 10.1016/S0003-9861(03)00213-3
-
(2003)
Arch. Biochem. Biophys
, vol.415
, pp. 6-13
-
-
Wang, X.1
Tokuda, H.2
Hatakeyama, D.3
Hirade, K.4
Niwa, M.5
Ito, H.6
-
211
-
-
0029938805
-
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
-
Wang, X. Z., and Ron, D. (1996). Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science 272, 1347-1349. doi: 10.1126/science.272.5266.1347
-
(1996)
Science
, vol.272
, pp. 1347-1349
-
-
Wang, X.Z.1
Ron, D.2
-
212
-
-
84904171725
-
The effects of flavonoids on bone
-
Welch, A. A., and Hardcastle, A. C. (2014). The effects of flavonoids on bone. Curr. Osteoporos. Rep. 12, 205-210. doi: 10.1007/s11914-014-0212-5
-
(2014)
Curr. Osteoporos. Rep
, vol.12
, pp. 205-210
-
-
Welch, A.A.1
Hardcastle, A.C.2
-
213
-
-
70249090092
-
Nuclear localization of p38 MAPK in response to DNA damage
-
Wood, C. D., Thornton, T. M., Sabio, G., Davis, R. A., and Rincon, M. (2009). Nuclear localization of p38 MAPK in response to DNA damage. Int. J. Biol. Sci. 5, 428-437. doi: 10.7150/ijbs.5.428
-
(2009)
Int. J. Biol. Sci
, vol.5
, pp. 428-437
-
-
Wood, C.D.1
Thornton, T.M.2
Sabio, G.3
Davis, R.A.4
Rincon, M.5
-
214
-
-
84871713201
-
Effects of vascular endothelial cells on osteogenic differentiation of noncontact co-cultured periodontal ligament stem cells under hypoxia
-
Wu, Y., Cao, H., Yang, Y., Zhou, Y., Gu, Y., Zhao, X., et al. (2013). Effects of vascular endothelial cells on osteogenic differentiation of noncontact co-cultured periodontal ligament stem cells under hypoxia. J. Periodont. Res. 48, 52-65. doi: 10.1111/j.1600-0765.2012.01503.x
-
(2013)
J. Periodont. Res
, vol.48
, pp. 52-65
-
-
Wu, Y.1
Cao, H.2
Yang, Y.3
Zhou, Y.4
Gu, Y.5
Zhao, X.6
-
215
-
-
0034067079
-
p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps
-
Wu, Z., Woodring, P. J., Bhakta, K. S., Tamura, K., Wen, F., Feramisco, J. R., et al. (2000). p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Mol. Cell. Biol. 20, 3951-3964. doi: 10.1128/MCB.20.11.3951-3964.2000
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 3951-3964
-
-
Wu, Z.1
Woodring, P.J.2
Bhakta, K.S.3
Tamura, K.4
Wen, F.5
Feramisco, J.R.6
-
216
-
-
0036133374
-
Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells
-
Xiao, G., Gopalakrishnan, R., Jiang, D., Reith, E., Benson, M. D., and Franceschi, R. T. (2002a). Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J. Bone Miner. Res. 17, 101-110. doi: 10.1359/jbmr.2002.17.1.101
-
(2002)
J. Bone Miner. Res
, vol.17
, pp. 101-110
-
-
Xiao, G.1
Gopalakrishnan, R.2
Jiang, D.3
Reith, E.4
Benson, M.D.5
Franceschi, R.T.6
-
217
-
-
0037184027
-
Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2
-
Xiao, G., Jiang, D., Gopalakrishnan, R., and Franceschi, R. T. (2002b). Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2. J. Biol. Chem. 277, 36181-36187. doi: 10.1074/jbc.M206057200
-
(2002)
J. Biol. Chem
, vol.277
, pp. 36181-36187
-
-
Xiao, G.1
Jiang, D.2
Gopalakrishnan, R.3
Franceschi, R.T.4
-
218
-
-
0034635477
-
MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1
-
Xiao, G., Jiang, D., Thomas, P., Benson, M. D., Guan, K., Karsenty, G., et al. (2000). MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. J. Biol. Chem. 275, 4453-4459. doi: 10.1074/jbc.275.6.4453
-
(2000)
J. Biol. Chem
, vol.275
, pp. 4453-4459
-
-
Xiao, G.1
Jiang, D.2
Thomas, P.3
Benson, M.D.4
Guan, K.5
Karsenty, G.6
-
219
-
-
57549087597
-
Role of NF-kappaB in hematopoietic niche function of osteoblasts after radiation injury
-
Xiao, M., Inal, C. E., Parekh, V. I., Li, X. H., and Whitnall, M. H. (2009). Role of NF-kappaB in hematopoietic niche function of osteoblasts after radiation injury. Exp. Hematol. 37, 52-64. doi: 10.1016/j.exphem.2008.09.001
-
(2009)
Exp. Hematol
, vol.37
, pp. 52-64
-
-
Xiao, M.1
Inal, C.E.2
Parekh, V.I.3
Li, X.H.4
Whitnall, M.H.5
-
220
-
-
84866103436
-
Oscillatory fluid flow elicits changes in morphology, cytoskeleton and integrin-associated molecules in MLO-Y4 cells, but not in MC3T3-E1 cells
-
Xu, H., Zhang, J., Wu, J., Guan, Y., Weng, Y., and Shang, P. (2012). Oscillatory fluid flow elicits changes in morphology, cytoskeleton and integrin-associated molecules in MLO-Y4 cells, but not in MC3T3-E1 cells. Biol. Res. 45, 163-169. doi: 10.4067/S0716-97602012000200008
-
(2012)
Biol. Res
, vol.45
, pp. 163-169
-
-
Xu, H.1
Zhang, J.2
Wu, J.3
Guan, Y.4
Weng, Y.5
Shang, P.6
-
221
-
-
0033521529
-
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
-
Yamaguchi, K., Nagai, S., Ninomiya-Tsuji, J., Nishita, M., Tamai, K., Irie, K., et al. (1999). XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J. 18, 179-187. doi: 10.1093/emboj/18.1.179
-
(1999)
EMBO J
, vol.18
, pp. 179-187
-
-
Yamaguchi, K.1
Nagai, S.2
Ninomiya-Tsuji, J.3
Nishita, M.4
Tamai, K.5
Irie, K.6
-
222
-
-
0034694833
-
Activation of p42/44 and p38 mitogen-activated protein kinases by extracellular calcium-sensing receptor agonists induces mitogenic responses in the mouse osteoblastic MC3T3-E1 cell line
-
Yamaguchi, T., Chattopadhyay, N., Kifor, O., Sanders, J. L., and Brown, E. M. (2000). Activation of p42/44 and p38 mitogen-activated protein kinases by extracellular calcium-sensing receptor agonists induces mitogenic responses in the mouse osteoblastic MC3T3-E1 cell line. Biochem. Biophys. Res. Commun. 279, 363-368. doi: 10.1006/bbrc.2000.3955
-
(2000)
Biochem. Biophys. Res. Commun
, vol.279
, pp. 363-368
-
-
Yamaguchi, T.1
Chattopadhyay, N.2
Kifor, O.3
Sanders, J.L.4
Brown, E.M.5
-
223
-
-
1842735414
-
Cross-talk between the estrogen receptor-, protein kinase A-, and mitogen-activated protein kinase-mediated signaling pathways in the regulation of lactotroph proliferation in primary culture
-
Yamakawa, K., and Arita, J. (2004). Cross-talk between the estrogen receptor-, protein kinase A-, and mitogen-activated protein kinase-mediated signaling pathways in the regulation of lactotroph proliferation in primary culture. J. Steroid Biochem. Mol. Biol. 88, 123-130. doi: 10.1016/j.jsbmb.2003.11.003
-
(2004)
J. Steroid Biochem. Mol. Biol
, vol.88
, pp. 123-130
-
-
Yamakawa, K.1
Arita, J.2
-
224
-
-
52049111663
-
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta
-
Yamashita, M., Fatyol, K., Jin, C., Wang, X., Liu, Z., and Zhang, Y. E. (2008). TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta. Mol. Cell 31, 918-924. doi: 10.1016/j.molcel.2008.09.002
-
(2008)
Mol. Cell
, vol.31
, pp. 918-924
-
-
Yamashita, M.1
Fatyol, K.2
Jin, C.3
Wang, X.4
Liu, Z.5
Zhang, Y.E.6
-
225
-
-
84886002180
-
Adiponectin impairs chicken preadipocytes differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways
-
Yan, J., Gan, L., Chen, D., and Sun, C. (2013). Adiponectin impairs chicken preadipocytes differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 kinase pathways. PLoS ONE 8:e77716. doi: 10.1371/journal.pone.0077716
-
(2013)
PLoS ONE
, vol.8
-
-
Yan, J.1
Gan, L.2
Chen, D.3
Sun, C.4
-
226
-
-
84946152174
-
Sambucus williamsii hance promotes MC3T3-E1 cells proliferation and differentiation via BMP-2/Smad/p38/JNK/Runx2 signaling pathway
-
Yang, B., Lin, X., Yang, C., Tan, J., Li, W., and Kuang, H. (2015a). Sambucus williamsii hance promotes MC3T3-E1 cells proliferation and differentiation via BMP-2/Smad/p38/JNK/Runx2 signaling pathway. Phytother. Res. 29, 1692-1699. doi: 10.1002/ptr.5482
-
(2015)
Phytother. Res
, vol.29
, pp. 1692-1699
-
-
Yang, B.1
Lin, X.2
Yang, C.3
Tan, J.4
Li, W.5
Kuang, H.6
-
227
-
-
84896507115
-
BMP-2 induction of Dlx3 expression is mediated by p38/Smad5 signaling pathway in osteoblastic MC3T3-E1 cells
-
Yang, G., Yuan, G., Li, X., Liu, P., Chen, Z., and Fan, M. (2014). BMP-2 induction of Dlx3 expression is mediated by p38/Smad5 signaling pathway in osteoblastic MC3T3-E1 cells. J. Cell. Physiol. 229, 943-954. doi: 10.1002/jcp.24525
-
(2014)
J. Cell. Physiol
, vol.229
, pp. 943-954
-
-
Yang, G.1
Yuan, G.2
Li, X.3
Liu, P.4
Chen, Z.5
Fan, M.6
-
228
-
-
84941646443
-
Bone morphogenetic protein 2-induced human dental pulp cell differentiation involves p38 mitogen-activated protein kinase-activated canonical WNT pathway
-
Yang, J., Ye, L., Hui, T. Q., Yang, D. M., Huang, D. M., Zhou, X. D., et al. (2015b). Bone morphogenetic protein 2-induced human dental pulp cell differentiation involves p38 mitogen-activated protein kinase-activated canonical WNT pathway. Int. J. Oral Sci. 7, 95-102. doi: 10.1038/ijos.2015.7
-
(2015)
Int. J. Oral Sci
, vol.7
, pp. 95-102
-
-
Yang, J.1
Ye, L.2
Hui, T.Q.3
Yang, D.M.4
Huang, D.M.5
Zhou, X.D.6
-
229
-
-
0036094148
-
Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases
-
Yang, T. T., Xiong, Q., Enslen, H., Davis, R. J., and Chow, C. W. (2002). Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol. Cell. Biol. 22, 3892-3904. doi: 10.1128/MCB.22.11.3892-3904.2002
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 3892-3904
-
-
Yang, T.T.1
Xiong, Q.2
Enslen, H.3
Davis, R.J.4
Chow, C.W.5
-
230
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome
-
Yang, X., Matsuda, K., Bialek, P., Jacquot, S., Masuoka, H. C., Schinke, T., et al. (2004). ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117, 387-398. doi: 10.1016/S0092-8674(04)00344-7
-
(2004)
Cell
, vol.117
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
-
231
-
-
77953464428
-
Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of beta1-integrin
-
Yeh, C. R., Chiu, J. J., Lee, C. I., Lee, P. L., Shih, Y. T., Sun, J. S., et al. (2010). Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of beta1-integrin. J. Bone Miner. Res. 25, 627-639. doi: 10.1359/jbmr.091008
-
(2010)
J. Bone Miner. Res
, vol.25
, pp. 627-639
-
-
Yeh, C.R.1
Chiu, J.J.2
Lee, C.I.3
Lee, P.L.4
Shih, Y.T.5
Sun, J.S.6
-
232
-
-
25144462239
-
Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts
-
Yen, M. L., Su, J. L., Chien, C. L., Tseng, K. W., Yang, C. Y., Chen, W. F., et al. (2005). Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts. Mol. Pharmacol. 68, 1061-1073. doi: 10.1124/mol.104.010082
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 1061-1073
-
-
Yen, M.L.1
Su, J.L.2
Chien, C.L.3
Tseng, K.W.4
Yang, C.Y.5
Chen, W.F.6
-
233
-
-
84865270952
-
Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling
-
Yu, B., Zhao, X., Yang, C., Crane, J., Xian, L., Lu, W., et al. (2012). Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling. J. Bone Miner. Res. 27, 2001-2014. doi: 10.1002/jbmr.1663
-
(2012)
J. Bone Miner. Res
, vol.27
, pp. 2001-2014
-
-
Yu, B.1
Zhao, X.2
Yang, C.3
Crane, J.4
Xian, L.5
Lu, W.6
-
234
-
-
84865746758
-
Migration of human mesenchymal stem cells under low shear stress mediated by mitogen-activated protein kinase signaling
-
Yuan, L., Sakamoto, N., Song, G., and Sato, M. (2012). Migration of human mesenchymal stem cells under low shear stress mediated by mitogen-activated protein kinase signaling. Stem Cells Dev. 21, 2520-2530. doi: 10.1089/scd.2012.0010
-
(2012)
Stem Cells Dev
, vol.21
, pp. 2520-2530
-
-
Yuan, L.1
Sakamoto, N.2
Song, G.3
Sato, M.4
-
235
-
-
84921876910
-
Electromagnetic wave irradiation promotes osteoblastic cell proliferation and up-regulates growth factors via activation of the ERK1/2 and p38 MAPK pathways
-
Yumoto, H., Hirao, K., Tominaga, T., Bando, N., Takahashi, K., and Matsuo, T. (2015). Electromagnetic wave irradiation promotes osteoblastic cell proliferation and up-regulates growth factors via activation of the ERK1/2 and p38 MAPK pathways. Cell. Physiol. Biochem. 35, 601-615. doi: 10.1159/000369722
-
(2015)
Cell. Physiol. Biochem
, vol.35
, pp. 601-615
-
-
Yumoto, H.1
Hirao, K.2
Tominaga, T.3
Bando, N.4
Takahashi, K.5
Matsuo, T.6
-
236
-
-
0033582459
-
p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation Participation of the Mef2c transcription factor
-
Zetser, A., Gredinger, E., and Bengal, E. (1999). p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor. J. Biol. Chem. 274, 5193-5200. doi: 10.1074/jbc.274.8.5193
-
(1999)
J. Biol. Chem
, vol.274
, pp. 5193-5200
-
-
Zetser, A.1
Gredinger, E.2
Bengal, E.3
-
237
-
-
84892422316
-
Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo
-
Zhai, Z. J., Li, H. W., Liu, G. W., Qu, X. H., Tian, B., Yan, W., et al. (2014). Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br. J. Pharmacol. 171, 663-675. doi: 10.1111/bph.12463
-
(2014)
Br. J. Pharmacol
, vol.171
, pp. 663-675
-
-
Zhai, Z.J.1
Li, H.W.2
Liu, G.W.3
Qu, X.H.4
Tian, B.5
Yan, W.6
-
238
-
-
84886791046
-
p38-MAPK signaling pathway is not involved in osteogenic differentiation during early response of mesenchymal stem cells to continuous mechanical strain
-
Zhang, P., Wu, Y., Dai, Q., Fang, B., and Jiang, L. (2013). p38-MAPK signaling pathway is not involved in osteogenic differentiation during early response of mesenchymal stem cells to continuous mechanical strain. Mol. Cell. Biochem. 378, 19-28. doi: 10.1007/s11010-013-1589-7
-
(2013)
Mol. Cell. Biochem
, vol.378
, pp. 19-28
-
-
Zhang, P.1
Wu, Y.2
Dai, Q.3
Fang, B.4
Jiang, L.5
-
239
-
-
84939263812
-
Apigenin promotes osteogenic differentiation of human mesenchymal stem cells through JNK and p38 MAPK pathways
-
Zhang, X., Zhou, C., Zha, X., Xu, Z., Li, L., Liu, Y., et al. (2015). Apigenin promotes osteogenic differentiation of human mesenchymal stem cells through JNK and p38 MAPK pathways. Mol. Cell. Biochem. 407, 41-50. doi: 10.1007/s11010-015-2452-9
-
(2015)
Mol. Cell. Biochem
, vol.407
, pp. 41-50
-
-
Zhang, X.1
Zhou, C.2
Zha, X.3
Xu, Z.4
Li, L.5
Liu, Y.6
-
240
-
-
55549104054
-
Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38alpha in different phosphorylation states
-
Zhang, Y. Y., Mei, Z. Q., Wu, J. W., and Wang, Z. X. (2008). Enzymatic activity and substrate specificity of mitogen-activated protein kinase p38alpha in different phosphorylation states. J. Biol. Chem. 283, 26591-26601. doi: 10.1074/jbc.M801703200
-
(2008)
J. Biol. Chem
, vol.283
, pp. 26591-26601
-
-
Zhang, Y.Y.1
Mei, Z.Q.2
Wu, J.W.3
Wang, Z.X.4
-
241
-
-
84921647351
-
Saikosaponin a inhibits RANKL-induced osteoclastogenesis by suppressing NF-kappaB and MAPK pathways
-
Zhou, C., Liu, W., He, W., Wang, H., Chen, Q., and Song, H. (2015). Saikosaponin a inhibits RANKL-induced osteoclastogenesis by suppressing NF-kappaB and MAPK pathways. Int. Immunopharmacol. 25, 49-54. doi: 10.1016/j.intimp.2015.01.010
-
(2015)
Int. Immunopharmacol
, vol.25
, pp. 49-54
-
-
Zhou, C.1
Liu, W.2
He, W.3
Wang, H.4
Chen, Q.5
Song, H.6
-
242
-
-
33745507931
-
TNF-alpha mediates p38 MAP kinase activation and negatively regulates bone formation at the injured growth plate in rats
-
Zhou, F. H., Foster, B. K., Zhou, X. F., Cowin, A. J., and Xian, C. J. (2006). TNF-alpha mediates p38 MAP kinase activation and negatively regulates bone formation at the injured growth plate in rats. J. Bone Miner. Res. 21, 1075-1088. doi: 10.1359/jbmr.060410
-
(2006)
J. Bone Miner. Res
, vol.21
, pp. 1075-1088
-
-
Zhou, F.H.1
Foster, B.K.2
Zhou, X.F.3
Cowin, A.J.4
Xian, C.J.5
-
243
-
-
84876746211
-
Hypoxia induces osteogenic/angiogenic responses of bone marrow-derived mesenchymal stromal cells seeded on bone-derived scaffolds via ERK1/2 and p38 pathways
-
Zhou, Y., Guan, X., Wang, H., Zhu, Z., Li, C., Wu, S., et al. (2013). Hypoxia induces osteogenic/angiogenic responses of bone marrow-derived mesenchymal stromal cells seeded on bone-derived scaffolds via ERK1/2 and p38 pathways. Biotechnol. Bioeng. 110, 1794-1804. doi: 10.1002/bit.24827
-
(2013)
Biotechnol. Bioeng
, vol.110
, pp. 1794-1804
-
-
Zhou, Y.1
Guan, X.2
Wang, H.3
Zhu, Z.4
Li, C.5
Wu, S.6
-
244
-
-
84871773355
-
Amphiregulin-EGFR signaling mediates the migration of bone marrow mesenchymal progenitors toward PTH-stimulated osteoblasts and osteocytes
-
Zhu, J., Siclari, V. A., Liu, F., Spatz, J. M., Chandra, A., Divieti Pajevic, P., et al. (2012). Amphiregulin-EGFR signaling mediates the migration of bone marrow mesenchymal progenitors toward PTH-stimulated osteoblasts and osteocytes. PLoS ONE 7:e50099. doi: 10.1371/journal.pone.0050099
-
(2012)
PLoS ONE
, vol.7
-
-
Zhu, J.1
Siclari, V.A.2
Liu, F.3
Spatz, J.M.4
Chandra, A.5
Divieti Pajevic, P.6
-
245
-
-
80555136829
-
MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice
-
Zou, W., Greenblatt, M. B., Shim, J. H., Kant, S., Zhai, B., Lotinun, S., et al. (2011). MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. J. Clin. Invest. 121, 4383-4392. doi: 10.1172/JCI59041
-
(2011)
J. Clin. Invest
, vol.121
, pp. 4383-4392
-
-
Zou, W.1
Greenblatt, M.B.2
Shim, J.H.3
Kant, S.4
Zhai, B.5
Lotinun, S.6
-
246
-
-
3042778695
-
A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways
-
Zuzarte-Luís, V., Montero, J. A., Rodriguez-Leon, J., Merino, R., Rodríguez-Rey, J. C., and Hurlé, J. M. (2004). A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways. Dev. Biol. 272, 39-52. doi: 10.1016/j.ydbio.2004.04.015
-
(2004)
Dev. Biol
, vol.272
, pp. 39-52
-
-
Zuzarte-Luís, V.1
Montero, J.A.2
Rodriguez-Leon, J.3
Merino, R.4
Rodríguez-Rey, J.C.5
Hurlé, J.M.6
|