TNFα and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics

Bone

Volumn 38, Issue 4, 2006, Pages 509-520

  Dai, Jia C ^a   He, Ping ^a   Chen, Xin ^a   Greenfield, Edward M ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Bone resorption; Cytokines; Immediate early genes; Osteoblast; Parathyroid hormone; Tumor necrosis factor

Indexed keywords

INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCLAST DIFFERENTIATION FACTOR; PARATHYROID HORMONE; TUMOR NECROSIS FACTOR ALPHA; CARRIER PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; PARATHYROID HORMONE (1 34); PARATHYROID HORMONE (1-34); PEPTIDE FRAGMENT; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TNFRSF11A PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; KINETICS; MOUSE; NONHUMAN; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; ANIMAL; BIOSYNTHESIS; CELL STRAIN 3T3; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

3T3 CELLS; ANIMALS; CARRIER PROTEINS; GENE EXPRESSION REGULATION; INTERLEUKIN-6; MEMBRANE GLYCOPROTEINS; MICE; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33645007357     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.10.007     Document Type: Article

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