Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells

Journal of Medical Investigation

Volumn 55, Issue 3-4, 2008, Pages 267-278

  Soda, Akira ^a   Ikehara, Toshitaka ^a,b   Kinouchi, Yohsuke ^a   Yoshizaki, Kazuo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b YASUDA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Collagen; ELF EMF; ERK1 2; MC3T3 E1 cell; Osteoblast; P38 MAPK; PI3K

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; COLLAGEN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CELL STRAIN 3T3; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ELECTROMAGNETIC FIELD; MOUSE; NONHUMAN; OSTEOBLAST; SIGNAL TRANSDUCTION; SPECTROSCOPY; STAINING;

EID: 56749174709     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: 10.2152/jmi.55.267     Document Type: Article

References (34)

1. Bassett CAL, Pawluk RJ, Becker RO: Effect of electrical currents on bone in vivo. Nature 204: 652-653, 1964
2. Basett CAL: Bioelectromagnetics in the service of medicine. In: Blanck M, ed. Electromagnetic Fields, Biological Interactions and Mechanisms. American Chemical Society, Washington DC, 1995, pp.261-275
3. Bassett CAL: Fundamental and practical aspects of therapeutic uses of pulsed electromagnetic fields (PEMFs). Crit Rev Biomed Eng 17: 451-529, 1989
4. +) uptake by HeLa cells. In: Ueno S, ed. Biological Effects of Magnetic and Electromagnetic Fields. Plenum Press, New York and London, 1996, pp.101-120
5. Ikehara T, Yamaguchi H, Miyamoto H: Effects of electromagnetic fields on membrane ion transport of cultured cells. J Med Invest 45: 47-56, 1998
6. Sato K, Yamaguchi H, Miyamoto H, Kinouchi Y: Growth of cultured cells exposed to a nonhomogeneous static magnetic field generated by Sm-Co magnets. Biochim Biophys Acta 1136: 231-238, 1992
7. Yamguchi H, Hosokawa K, Soda A, Miyamoto H, Kinouchi Y: Effects of seven months' exposure to a static 0.2 T magnetic field on growth and glycolytic activity of human gingival fibroblasts. Biochim Biophys Acta 1156: 302-306, 1993
8. + induced by bradykinin in cultured bovine adrenal chromaffin cells. FEBS Lett 435: 229-232, 1998
9. 2+ in cultured pheochromocytoma cells. Biochim Biophys Acta 1724: 8-16, 2005
10. +) fluxes and surface charge of HeLa cells. Jpn J Physiol 42: 929-943, 1992
11. Ikehara T, Yamaguchi H, Hosokawa K, Miyamoto H, Aizawa K: Effects of ELF magnetic field on membrane protein structure of living HeLa cells studied by Fourier transform infrared spectroscopy. Bioelectromagnetics 24: 457-464, 2003
12. Lee JH, McLeod KJ: Morphologic responses of osteoblast-like cells in monolayer culture to ELF electromagnetic fields. Bioelectromagnetics 21: 129-136, 2000
13. Löschinger M, Thumm S, Hämmerle H, Rodemann HP: Stimulation of protein kinase A activity and induced terminal differentiation of human skin fibroblasts in culture by lowfrequency electromagnetic fields. Toxicol Lett 96-97: 369-376, 1998
14. Sudo H, Kodama H, Amagai Y, Yamamoto S, Kasai S: In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 6: 191-198, 1983
15. Suzuki A, Guicheux J, Palmer G, Miura Y, Olso Y, Bonjour JP, Caverzasio J: Evidence for a role of p-38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation. Bone 30: 91-98, 2002
16. Hanai Y, Tokuda H, Ishisaki A, Matsushima-Nishiwaki R, Nakamura N, Yoshida M, Takai S, Ohta T, Kozawa O: Involvement of p44/p 42 MAP kinase in insulin-like growth factor induced alkaline phosphatase activity in osteoblast-like-MC3T3-E1 cells. Mol Cell Endocrinol 251: 42-48, 2006
17. Chakravarthy MV, Abraha TW, Schwartz RJ, Fiorotto ML Booth FW: Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3′-kinase/Akt signaling pathway. J Biol Chem 275: 35942-35952, 2000
18. Kuemmerle JF, Zhou H, Bowers JG: IGF-I stimulates human intestinal smooth muscle cell growth by regulation of G1 phase cell cycle proteins. Am J Physiol 286: G412-G419, 2004
19. Grey A, Chen Q, Xu X, Callon K, Cornish J: Parallel phosphatidylinositol - 3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells. Endocrinology 144: 4886-4893, 2003
20. Boguslawski G, Hale LV, Yu X-P, Miles RR, Onyia JE, Santerre RF, Chandrase KS: Activation of osteocalcin transcription involves interaction of protein kinase A- and protein kinase C-dependent pathways. J Biol Chem 275: 999-1006, 2000
21. Sowa H, Kaji H, Yamaguchi T, Sugimoto T, Chihara K: Activation of ERK1/2 and JNK by transforming growth factor β negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells. J Biol Chem 277: 36024-36031, 2002
22. Leon AL, Rojkind M: A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections. J Histochem Cytochem 33: 737-743, 1985
23. Olivarez-Banuelos T, Navarro L, Gonzalez A, Drucker-Colin R: Differentiation of chromaffin cells elicited by ELF- MF modifies gene expression pattern. Cell Biol Intern 28: 273-279, 2004
24. Manni V, Lisi A, Rieti S, Serafino A, Ledda M, Giuliani L, Sacco D, D'Emilia E, Grimaldi S: Low electromagnetic field (50 Hz) induces differentiation on primary human oral keratinocytes (HOK). Bioelectromagnetics 25: 118-126, 2004
25. Yamaguchi, DT, Huang J, Defang, MA, Wang PKC: Inhibition of gap junction intercellular communication by extremely low-frequency electromagnetic fields in osteoblast-like models is dependent on cell differentiation. J Cell Physiol 190: 180-188, 2002.
26. Diniz P, Shomura K, Soejima K, and Ito G: Effects of pulsed electromagnetic field (PEMF) stimulation on bone tissue like formation are dependent on the maturation stages of the osteoblasts. Bioelectromagnetics 23: 398-405, 2002
27. Kono S, Oshima Y, Hoshi K, Bonewald LF, Oda H, Nakamura K, Kawaguchi H, Tanaka S: Erk pathways negatively regulate matrix mineralization. Bone 40: 68-74, 2007
28. Hu Y, Chan E, Wang SX, Li B: Activation of p 38 mitogen-activated kinase is required for osteoblast differentiation. Endocrinology 144: 2068-2074, 2003
29. Khatiwala CB, Peyton SR, Metzke M, Putnam AJ: The regulation of osteogenesis by ECM rigidity in MC3T3-E1 cells requires MAP activation. J Cell Physiol 211: 661-672, 2007
30. Golden LH, Insogna KL: The expanding role of PI3-kinase in bone. Bone 34: 3-12, 2004
31. Noda T, Tokuda H, Yoshida M, Yasuda E, Hanai Y, Takai S, Kozawa O: Possible involvement of phosphatidylinositol 3-kinase/Akt pathway in insulin-like growth factor-induced alkaline phosphatase activity in osteoblasts. Horm Metab Res 37: 270-274, 2005
32. Guicheux J, Lemonnier J, Ghayor C, Suzuki A, Palmer G, Caverzasio J: Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation. J Bone Miner Res 18: 2060-2068, 2003
33. Rey A, Manen D, Rizzoli R, Ferrari SL, Caverzasio J: Evidences for a role of p38 MAP kinase in the stimulation of alkaline phosphatase and matrix mineralizaion induced by parathyroid hormone in osteoblastic cells. Bone 41: 59-67, 2007
34. Kozawa O, Hatakeyama D, Uematsu T: Divergent regulation by p44/p42 MAP and p38 kinase of bone morphogenetic protein-4-stimulated osteocalcin synthsis in osteoblasts. J Cell Biochem 84: 583-589, 2002