Osterix induces Col1a1 gene expression through binding to Sp1 sites in the bone enhancer and proximal promoter regions

Bone

Volumn 52, Issue 2, 2013, Pages 548-556

  Ortuño, Maria José ^a   Susperregui, Antonio R G ^a   Artigas, Natalia ^a   Rosa, José Luis ^a   Ventura, Francesc ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

BMP; Col1a1; Osteoblast differentiation; Osterix; Runx2

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; BINDING SITE; COLLAGEN TYPE 1 GENE; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; CELL LINE; COLLAGEN TYPE I; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84875024063     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.11.007     Document Type: Article

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