The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase α. Implications for signal/response profiles of MAP kinase pathways

Journal of Biological Chemistry

Volumn 276, Issue 8, 2001, Pages 5676-5684

  Waas, William F ^a   Lo, Herng Hsiang ^a   Dalby, Kevin N ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; CELLS; COMPUTER SIMULATION;

SIGNAL TRANSDUCTION PATHWAYS;

ENZYMES;

ACTIVATING TRANSCRIPTION FACTOR 2; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THREONINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ATF2 PROTEIN, RAT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDE FRAGMENT;

ARTICLE; COMPUTER SIMULATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL MODEL; FORECASTING; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; RAT;

EUKARYOTA;

ACTIVATING TRANSCRIPTION FACTOR 2; AMINO ACID SEQUENCE; ANIMALS; COMPUTER SIMULATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FORECASTING; GLUTATHIONE TRANSFERASE; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; RATS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; THREONINE; TRANSCRIPTION FACTORS;

EID: 0035937158     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008787200     Document Type: Article

References (52)

1. Cobb, M. H. (1999) Prog. Biophys. Mol. Biol. 71, 479-500
2. Widmann, C., Gibson, S., Jarpe, M. B., and Johnson, G. L. (1999) Physiol. Rev. 79, 143-180
3. Jacobs, D., Glossip, D., Xing, H., Muslin, A. J., and Kornfeld, K. (1999) Genes Dev. 13, 163-175
4. Keyse, S. M. (2000) Curr. Opin. Cell Biol. 12, 186-192
5. Camps, M., Nichols, A., and Arkinstall, S. (2000) FASEB J. 14, 6-16
6. Keyse, S. M. (1999) Free Radic. Res. 31, 341-349
7. Aggen, J. B., Nairn, A. C., and Chamberlin, R. (2000) Chem. Biol. 7, R13-R23
8. Virshup, D. M. (2000) Curr. Opin. Cell Biol. 12, 180-185
9. Millward, T. A., Zolnierowicz, S., and Hemmings, B. A. (1999) Trends Biochem. Sci. 24, 186-191
10. Goldberg, Y. (1999) Biochem. Pharmacol. 57, 321-328
11. Ferrell, J. E., Jr. (1996) Trends Biochem. Sci. 21, 460-466
12. Goldbeter, A., and Koshland, D. E., Jr. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 6840-6844
13. Koshland, D. E., Jr., Goldbeter, A., and Stock, J. B. (1982) Science 217, 220-225
14. Ferrell, J. E., Jr. (1998) Trends Biochem. Sci. 23, 461-465
15. Ferrell, J. E., Jr., and Bhatt, R. R. (1997) J. Biol. Chem. 272, 19008-19016
16. Burack, W. R., and Sturgill, T. W. (1997) Biochemistry 36, 5929-5933
17. Huang, C. Y., and Ferrell, J. E., Jr. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 10078-10083
18. LoGrasso, P. V., Frantz, B., Rolando, A. M., O'Keefe, S. J., Hermes, J. D., and O'Neill, E. A. (1997) Biochemistry 36, 10422-10427
19. Han, J., Lee, J. D., Bibbs, L., and Ulevitch, R. J. (1994) Science 265, 808-811
20. Lee, J. C., Laydon, J. T., McDonnell, P. C., Gallagher, T. F., Kumar, S., Green, D., McNulty, D., Blumenthal, M. J., Heys, J. R., Landvatter, S. W., et al. (1994) Nature 372, 739-746
21. Han, J., Lee, J. D., Jiang, Y., Li, Z., Feng, L., and Ulevitch, R. J. (1996) J. Biol. Chem. 271, 2886-2891
22. Cuenda, A., Cohen, P., Buee-Scherrer, V., and Goedert, M. (1997) EMBO J. 16, 295-305
23. Porter, A. C., Fanger, G. R., and Vaillancourt, R. R. (1999) Oncogene 18, 7794-7802
24. Takekawa, M., and Saito, H. (1998) Cell 95, 521-530
25. Gerwins, P., Blank, J. L., and Johnson, G. L. (1997) J. Biol. Chem. 272, 8288-8295
26. Tobiume, K., Inage, T., Takeda, K., Enomoto, S., Miyazono, K., and Ichijo, H. (1997) Biochem. Biophys. Res. Commun. 239, 905-910
27. Ichijo, H., Nishida, E., Irie, K., ten Dijke, P., Saitoh, M., Moriguchi, T., Takagi, M., Matsumoto, K., Miyazono, K., and Gotoh, Y. (1997) Science 275, 90-94
28. Hirose, T., Fujimoto, W., Tamaai, T., Kim, K. H., Matsuura, H., and Jetten, A. M. (1994) Mol. Endocrinol. 8, 1667-1680
29. Moriguchi, T., Kuroyanagi, N., Yamaguchi, K., Gotoh, Y., Irie, K., Kano, T., Shirakabe, K., Muro, Y., Shibuya, H., Matsumoto, K., Nishida, E., and Hagiwara, M. (1996) J. Biol. Chem. 271, 13675-13679
30. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., and Matsumoto, K. (1995) Science 270, 2008-2011
31. Kawasaki, H., Schiltz, L., Chiu, R., Itakura, K., Taira, K., Nakatani, Y., and Yokoyama, K. K. (2000) Nature 405, 195-200
32. van Dam, H., Wilhelm, D., Herr, I., Steffen, A., Herrlich, P., and Angel, P. (1995) EMBO J. 14, 1798-1811
33. Fuchs, S. Y., Tappin, I., and Ronai, Z. (2000) J. Biol. Chem. 275, 12560-12564
34. Wang, Z., Harkins, P. C., Ulevitch, R. J., Han, J., Cobb, M. H., and Goldsmith, E. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2327-2332
35. Khokhlatchev, A., Xu, S., English, J., Wu, P., Schaefer, E., and Cobb, M. H. (1997) J. Biol. Chem. 272, 11057-11062
36. Kemp, B. E., Benjamini, E., and Krebs, E. G. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 1038-1042
37. Gill, S. C., and von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326
38. Roepstorff, P., and Fohlman, J. (1984) Biomed. Mass Spectrom. 11, 601
39. Barshop, B. A., Wrenn, R. F., and Frieden, C. (1983) Anal. Biochem. 130, 134-145
40. Cornish-Bowden, A. (1995) Fundamentals of Enzyme Kinetics, pp. 297-315, Portland Press Ltd., London
41. Tanoue, T., Adachi, M., Moriguchi, T., and Nishida, E. (2000) Nat. Cell Biol. 2, 110-116
42. Songyang, Z., Blechner, S., Hoagland, N., Hoekstra, M. F., Piwnica-Worms, H., and Cantley, L. C. (1994) Curr. Biol. 4, 973-982
43. Gavin, A. C., and Nebreda, A. R. (1999) Curr. Biol. 9, 281-284
44. Smith, J. A., Poteet-Smith, C. E., Malarkey, K., and Sturgill, T. W. (1999) J. Biol. Chem. 274, 2893-2898
45. Levchenko, A., Bruck, J., and Sternberg, P. W. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5818-5823
46. Chen, G., Porter, M. D., Bristol, J. R., Fitzgibbon, M. J., and Pazhanisamy, S. (2000) Biochemistry 39, 2079-2087
47. Gum, R. J., and Young, P. R. (1999) Biochem. Biophys. Res. Commun. 266, 284-289
48. Yang, S. H., Yates, P. R., Whitmarsh, A. J., Davis, R. J., and Sharrocks, A. D. (1998) Mol. Cell. Biol. 18, 710-720
49. Kallunki, T., Su, B., Tsigelny, I., Sluss, H. K., Derijard, B., Moore, G., Davis, R., and Karin, M. (1994) Genes Dev. 8, 2996-3007
50. Ferrell, J. E., Jr., and Machleder, E. M. (1998) Science 280, 895-898
51. Wang, X. Z., and Ron, D. (1996) Science 272, 1347-1349
52. Zhao, M., New, L., Kravchenko, V. V., Kato, Y., Gram, H., di Padova, F., Olson, E. N., Ulevitch, R. J., and Han, J. (1999) Mol. Cell. Biol. 19, 21-30