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Volumn 25, Issue 3, 2010, Pages 627-639

Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of β1-integrin

Author keywords

Estrogen; Gene expression; Integrin; MAPK; Osteoblast; Shear stress

Indexed keywords

BETA1 INTEGRIN; CYCLOOXYGENASE 2; ESTRADIOL; ESTROGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C FOS; SMALL INTERFERING RNA; ESTROGEN;

EID: 77953464428     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.091008     Document Type: Article
Times cited : (36)

References (46)
  • 1
    • 0028903329 scopus 로고
    • Inhibition of bone resorption and stimulation of formulation by mechanical loading of the modeling rat ulna in vivo
    • Hillam RA, Skerry TM. Inhibition of bone resorption and stimulation of formulation by mechanical loading of the modeling rat ulna in vivo. J Bone Miner Res. 1995;10:683-689.
    • (1995) J Bone Miner Res , vol.10 , pp. 683-689
    • Hillam, R.A.1    Skerry, T.M.2
  • 2
    • 13444276396 scopus 로고    scopus 로고
    • Signal transduction and mechanical stress
    • Hughes-Fulford M. Signal transduction and mechanical stress. Sci STKE. 2004;249:RE12.
    • (2004) Sci STKE , vol.249
    • Hughes-Fulford, M.1
  • 4
    • 0037345529 scopus 로고    scopus 로고
    • Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways
    • DOI 10.1016/S8756-3282(02)00979-1
    • Kapur S, Baylink DJ, Lau KH. Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Bone. 2003;32:241-251. (Pubitemid 36349527)
    • (2003) Bone , vol.32 , Issue.3 , pp. 241-251
    • Kapur, S.1    Baylink, D.J.2    Lau, K.-H.W.3
  • 5
    • 0032437812 scopus 로고    scopus 로고
    • Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions
    • Pavalko FM, Chen NX, Turner CH, et al. Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions. Am J Physiol. 1998;275:C1591-1601.
    • (1998) Am J Physiol , vol.275
    • Pavalko, F.M.1    Chen, N.X.2    Turner, C.H.3
  • 6
    • 33747382145 scopus 로고    scopus 로고
    • Mechanical loading of bone in vivo causes bone formation through early induction of c-fos but not c-jun or c-myc
    • Turner CH, Tu Y, Onyia JE. Mechanical loading of bone in vivo causes bone formation through early induction of c-fos but not c-jun or c-myc. Ann Biomed Eng. 1996;24:S74.
    • (1996) Ann Biomed Eng , vol.24
    • Turner, C.H.1    Tu, Y.2    Onyia, J.E.3
  • 7
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • Forwood MR. Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J Bone Miner Res. 1996;11:1688-1693.
    • (1996) J Bone Miner Res , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 8
    • 84967614664 scopus 로고    scopus 로고
    • Sex steroids and the construction and conservation of the adult skeleton
    • DOI 10.1210/er.23.3.279
    • Riggs BL, Khosla S, Melton LJ. Sex steroids and construction and conservation of the adult skeleton. Endoc Rev. 2002;23:279-302. (Pubitemid 34651948)
    • (2002) Endocrine Reviews , vol.23 , Issue.3 , pp. 279-302
    • Riggs, B.L.1    Khosla, S.2    Melton III, L.J.3
  • 9
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenesis of osteoporosis: Concepts, conflicts, and prospects
    • Raisz LG. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J Clin Invest. 2005;115:3318-3325.
    • (2005) J Clin Invest , vol.115 , pp. 3318-3325
    • Raisz, L.G.1
  • 10
    • 0036128710 scopus 로고    scopus 로고
    • Human osteoblast proliferative responses to strain and 17β-estradiol are mediated by the estrogen receptor and receptor for insulin-like growth factor I
    • Cheng MZ, Rawlinson CF, Pitsillides AA, et al. Human osteoblast proliferative responses to strain and 17β-estradiol are mediated by the estrogen receptor and receptor for insulin-like growth factor I. J Bone Miner Res. 2002;17:593-602.
    • (2002) J Bone Miner Res , vol.17 , pp. 593-602
    • Cheng, M.Z.1    Rawlinson, C.F.2    Pitsillides, A.A.3
  • 11
    • 0032030503 scopus 로고    scopus 로고
    • Estrogen enhance differentiation of osteoblasts in mouse bone marrow culture
    • Qu Q, Perä lä-Heape M, Kapanen A, et al. Estrogen enhance differentiation of osteoblasts in mouse bone marrow culture. Bone. 1998;22:201-209.
    • (1998) Bone , vol.22 , pp. 201-209
    • Qu, Q.1    Perä Lä-Heape, M.2    Kapanen, A.3
  • 12
    • 14844283132 scopus 로고    scopus 로고
    • Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation
    • DOI 10.1074/jbc.M412817200
    • Plotkin LI, Aguirre JI, Kousteni S, Manolagas SC, Bellido T. Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation. J Biol Chem. 2005;280:7317-7325. (Pubitemid 40341290)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.8 , pp. 7317-7325
    • Plotkin, L.I.1    Aguirre, J.I.2    Kousteni, S.3    Manolagas, S.C.4    Bellido, T.5
  • 16
    • 0028436640 scopus 로고
    • Identification of integrin receptors on cultured human bone cells
    • DOI 10.1002/jor.1100120311
    • Saito T, Albelda SM, Brighton CT. Identification of integrin receptors on cultured human bone cells. J Orthop Res. 1994;12:384-394. (Pubitemid 24181142)
    • (1994) Journal of Orthopaedic Research , vol.12 , Issue.3 , pp. 384-394
    • Saito, T.1    Albelda, S.M.2    Brighton, C.T.3
  • 18
    • 0036843301 scopus 로고    scopus 로고
    • Role of integrins in endothelial mechanosensing of shear stress
    • DOI 10.1161/01.RES.0000038487.19924.18
    • Shyy JY, Chien S. Role of integrins in endothelial mechanosensing of shear stress. Circ Res. 2002;91:769-775. (Pubitemid 35285073)
    • (2002) Circulation Research , vol.91 , Issue.9 , pp. 769-775
    • Shyy, J.Y.-J.1    Chien, S.2
  • 20
    • 0028149286 scopus 로고
    • Are MG-63 and HOS TE85 human osteosarcoma cell lines representative models of the osteoblastic phenotype?
    • Clover J, Gowen M. Are MG-63 and HOS TE85 human osteosarcoma cell lines representative models of the osteoblastic phenotype? Bone. 1994;15:585-591.
    • (1994) Bone , vol.15 , pp. 585-591
    • Clover, J.1    Gowen, M.2
  • 21
    • 41649091020 scopus 로고    scopus 로고
    • Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad
    • Chang SF, Chang CA, Lee DY, et al. Tumor cell cycle arrest induced by shear stress: roles of integrins and Smad. Proc Natl Acad Sci USA. 2008;105:3927-3932.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3927-3932
    • Chang, S.F.1    Chang, C.A.2    Lee, D.Y.3
  • 23
    • 13444256417 scopus 로고    scopus 로고
    • Mechanisms of sex steroid effects on bone
    • DOI 10.1016/j.bbrc.2004.11.097, Vertebrate Skeletal Biology
    • Syed F, Khosla S. Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun. 2005;328:688-696. (Pubitemid 40214350)
    • (2005) Biochemical and Biophysical Research Communications , vol.328 , Issue.3 , pp. 688-696
    • Syed, F.1    Khosla, S.2
  • 24
    • 3242726055 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase-1 and -2 are both essential for the shear stress-induced human osteoblast proliferation
    • DOI 10.1016/j.bone.2004.04.007, PII S8756328204001693
    • Kapur S, Chen ST, Baylink DJ, Lau KH. Extracellular signal-regulated kinase-1 and -2 are both essential for the shear stress-induced human osteoblast proliferation. Bone. 2004;35:525-534. (Pubitemid 38953201)
    • (2004) Bone , vol.35 , Issue.2 , pp. 525-534
    • Kapur, S.1    Chen, S.-T.2    Baylink, D.J.3    Lau, K.-H.W.4
  • 25
    • 0036246273 scopus 로고    scopus 로고
    • Effects of biomechanical stress on bones in animals
    • Burr DB, Robling AG, Turner CH. Effects of biomechanical stress on bones in animals. Bone. 2002;30:781-786.
    • (2002) Bone , vol.30 , pp. 781-786
    • Burr, D.B.1    Robling, A.G.2    Turner, C.H.3
  • 26
    • 0029804794 scopus 로고    scopus 로고
    • Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone
    • Jagger CJ, Chow WM, Chambers TJ. Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone. J Clin Invest. 1996;98:2351-2357.
    • (1996) J Clin Invest , vol.98 , pp. 2351-2357
    • Jagger, C.J.1    Chow, W.M.2    Chambers, T.J.3
  • 30
    • 4444236062 scopus 로고    scopus 로고
    • Osteoblast-like cells from estrogen receptor a knockout mice have deficient responses to mechanical strain
    • Jessop HL, Suswillo FL, Rawlinson CF, et al. Osteoblast-like cells from estrogen receptor a knockout mice have deficient responses to mechanical strain. J Bone Miner Res. 2004;19:938-946.
    • (2004) J Bone Miner Res , vol.19 , pp. 938-946
    • Jessop, H.L.1    Suswillo, F.L.2    Rawlinson, C.F.3
  • 31
    • 0033791733 scopus 로고    scopus 로고
    • Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females
    • Damien E, Price JS, Lanyon LE. Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females. J Bone Miner Res. 2000;15:2169-2177.
    • (2000) J Bone Miner Res , vol.15 , pp. 2169-2177
    • Damien, E.1    Price, J.S.2    Lanyon, L.E.3
  • 32
    • 34548500327 scopus 로고    scopus 로고
    • A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblasts mechanotransduction
    • Aguirre JI, Plotkin LI, Gortazar AR, et al. A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblasts mechanotransduction. J Biol Chem. 2007;282:25501-25508.
    • (2007) J Biol Chem , vol.282 , pp. 25501-25508
    • Aguirre, J.I.1    Plotkin, L.I.2    Gortazar, A.R.3
  • 33
    • 33947493332 scopus 로고    scopus 로고
    • Regulation of endothelial cell cycle by laminar versus oscillatory flow: Distinct modes of interactions of AMP-activated protein kinase and akt pathways
    • DOI 10.1161/01.RES.0000259561.23876.c5, PII 0000301220070302000016
    • Guo D, Chien S, Shyy JYJ. Regulation of endothelia cell cycle by laminar versus oscillatory flow: distinct model of interactions of AMP-activated protein kinase and Akt pathway. Circ Res. 2007;100:564-571. (Pubitemid 46673266)
    • (2007) Circulation Research , vol.100 , Issue.4 , pp. 564-571
    • Guo, D.1    Chien, S.2    Shyy, J.Y.-J.3
  • 34
    • 23944499058 scopus 로고    scopus 로고
    • Mechanical stimulation prevents osteocyte apoptosis: Requirement of integrins, Src kinases, and ERKs
    • DOI 10.1152/ajpcell.00278.2004
    • Plotkin LI, Mathoy I, Aguirre JI, Parfitt AM, Manolagas SC, Bellido T. Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs. Am J Physiol. 2005;289:633-643. 35. Beeson PB. Age and sex association of 40 autoimmune diseases. Am J Med. 1994;96:457-462. (Pubitemid 41192673)
    • (2005) American Journal of Physiology - Cell Physiology , vol.289 , Issue.3
    • Plotkin, L.I.1    Mathov, I.2    Aguirre, J.I.3    Parfitt, A.M.4    Manolagas, S.C.5    Bellido, T.6
  • 35
    • 0028912040 scopus 로고
    • Postmenopausal estrogen therapy and the risk for developing system lupus erythematosus
    • Sánchez-Guerrero J, Liang MH, Karlson EW. Postmenopausal estrogen therapy and the risk for developing system lupus erythematosus. Ann Intern Med. 1995;122:430-432.
    • (1995) Ann Intern Med , vol.122 , pp. 430-432
    • Sánchez-Guerrero, J.1    Liang, M.H.2    Karlson, E.W.3
  • 37
    • 0029034446 scopus 로고
    • Selective expression of fos- and jun-realted genes during osteoblasts proliferation and differenation
    • Mccade LR, Kockx M, Lian J, Stein J, Stein G. Selective expression of fos- and jun-realted genes during osteoblasts proliferation and differenation. Exp Cell Res. 1995;218:255-262.
    • (1995) Exp Cell Res , vol.218 , pp. 255-262
    • Mccade, L.R.1    Kockx, M.2    Lian, J.3    Stein, J.4    Stein, G.5
  • 38
    • 0023685660 scopus 로고
    • Expression of the c-fos proto-oncogene in bone, cartilage and tooth forming tissue during mouse development
    • Caubet JF, Bernaudin JF. Expression of the c-fos proto-oncogene in bone, cartilage and tooth forming tissue during mouse development. Biol Cell. 1988;64:101-104.
    • (1988) Biol Cell , vol.64 , pp. 101-104
    • Caubet, J.F.1    Bernaudin, J.F.2
  • 42
    • 33747382145 scopus 로고    scopus 로고
    • Mechanical loading of bone in vivo causes bone formation through early induction of c-fos but not c-jun or c-myc
    • Turner CH, Tu Y, Onyia JE. Mechanical loading of bone in vivo causes bone formation through early induction of c-fos but not c-jun or c-myc. Ann Biomed Eng. 1996;24:S74.
    • (1996) Ann Biomed Eng , vol.24
    • Turner, C.H.1    Tu, Y.2    Onyia, J.E.3
  • 43
    • 27644522438 scopus 로고    scopus 로고
    • 2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells
    • DOI 10.1016/j.plefa.2005.08.005, PII S0952327805001390
    • Coetzee M, Haag M, Claassen N, Kruger MC. Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG63 cells and MC3T3-E1 osteoblast-like cells. Prostagland Leukotr Essent Fatty Acids. 2005;73:423-430. (Pubitemid 41563006)
    • (2005) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.73 , Issue.6 , pp. 423-430
    • Coetzee, M.1    Haag, M.2    Claassen, N.3    Kruger, M.C.4
  • 44
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • Forwood MR. Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J Bone Miner Res. 1996;11:1688-1693.
    • (1996) J Bone Miner Res , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 46


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