Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Wanachewin, Orawan ^a   Boonmaleerat, Kanchanit ^a   Pothacharoen, Peraphan ^a   Reutrakul, Vichai ^b   Kongtawelert, Prachya ^a  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b Mahidol University ^*  (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84861543050     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-71     Document Type: Article

References (39)

1. Sambrook P, Cooper C. Osteoporosis Lancet 2006, 367(9527):2010-2018.
2. Rodan GA, Martin TJ. Therapeutic approaches to bone diseases. Science 2000, 289(5484):1508-1514. 10.1126/science.289.5484.1508, 10968781.
3. Reid IR. Anti-resorptive therapies for osteoporosis. Semin Cell Dev Biol 2008, 19(5):473-478. 10.1016/j.semcdb.2008.08.002, 18760372.
4. Khosla S, Westendorf JJ, Oursler MJ. Building bone to reverse osteoporosis and repair fractures. J Clin Invest 2008, 118(2):421-428. 10.1172/JCI33612, 2214701, 18246192.
5. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284(5411):143-147. 10.1126/science.284.5411.143, 10102814.
6. Komori T. Regulation of osteoblast differentiation by transcription factors. J Cell Biochem 2006, 99(5):1233-1239. 10.1002/jcb.20958, 16795049.
7. Harada S, Rodan GA. Control of osteoblast function and regulation of bone mass. Nature 2003, 423(6937):349-355. 10.1038/nature01660, 12748654.
8. Yamaguchi A, Komori T, Suda T. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1. Endocr Rev 2000, 21(4):393-411. 10.1210/er.21.4.393, 10950158.
9. Termaat MF, Den Boer FC, Bakker FC, Patka P, Haarman HJ. Bone morphogenetic proteins. Development and clinical efficacy in the treatment of fractures and bone defects. J Bone Joint Surg Am 2005, 87(6):1367-1378.
10. Johnson GL, Vaillancourt RR. Sequential protein kinase reactions controlling cell growth and differentiation. Curr Opin Cell Biol 1994, 6(2):230-238. 10.1016/0955-0674(94)90141-4, 8024815.
11. Seger R, Krebs EG. The MAPK signaling cascade. FASEB J 1995, 9(9):726-735.
12. Zhang W, Liu HT. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 2002, 12(1):9-18. 10.1038/sj.cr.7290105, 11942415.
13. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 2001, 410(6824):37-40. 10.1038/35065000, 11242034.
14. Gallea S, Lallemand F, Atfi A, Rawadi G, Ramez V, Spinella-Jaegle S, et al. Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells. Bone 2001, 28(5):491-498. 10.1016/S8756-3282(01)00415-X, 11344048.
15. Ge C, Xiao G, Jiang D, Franceschi RT. Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J Cell Biol 2007, 176(5):709-718. 10.1083/jcb.200610046, 2064027, 17325210.
16. Lai CF, Chaudhary L, Fausto A, Halstead LR, Ory DS, Avioli LV, et al. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells. J Biol Chem 2001, 276(17):14443-14450.
17. Noth U, Tuli R, Seghatoleslami R, Howard M, Shah A, Hall DJ, et al. Activation of p38 and Smads mediates BMP-2 effects on human trabecular bone-derived osteoblasts. Exp Cell Res 2003, 291(1):201-211. 10.1016/S0014-4827(03)00386-0, 14597420.
18. Jeng KCG, Hou RCW. Sesamin and Sesamolin: Natures Therapeutic Lignans. Curr Enzym Inhib 2005, 1:11-20.
19. Boulbaroud S, Mesfioui A, Arfaoui A, Ouichou A, El-Hessni A. Preventive effects of flaxseed and sesame oil on bone loss in ovariectomized rats. Pak J Biol Sci 2008, 11(13):1696-1701. 10.3923/pjbs.2008.1696.1701, 18819621.
20. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25(4):402-408. 10.1006/meth.2001.1262, 11846609.
21. Gregory CA, Gunn WG, Peister A, Prockop DJ. An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Anal Biochem 2004, 329(1):77-84. 10.1016/j.ab.2004.02.002, 15136169.
22. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65(1-2):55-63.
23. Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature 2003, 423(6937):337-342. 10.1038/nature01658, 12748652.
24. Reinholz GG, Getz B, Pederson L, Sanders ES, Subramaniam M, Ingle JN, et al. Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts. Cancer Res 2000, 60(21):6001-6007.
25. Setzer B, Bachle M, Metzger MC, Kohal RJ. The gene-expression and phenotypic response of hFOB 1.19 osteoblasts to surface-modified titanium and zirconia. Biomaterials 2009, 30(6):979-990. 10.1016/j.biomaterials.2008.10.054, 19027946.
26. Lecoeur L, Ouhayoun JP. In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells. Biomaterials 1997, 18(14):989-993. 10.1016/S0142-9612(97)00025-2, 9212194.
27. Strem BM, Hicok KC, Zhu M, Wulur I, Alfonso Z, Schreiber RE, et al. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 2005, 54(3):132-141. 10.2302/kjm.54.132, 16237275.
28. Singhatanadgit W, Salih V, Olsen I. RNA interference of the BMPR-IB gene blocks BMP-2-induced osteogenic gene expression in human bone cells. Cell Biol Int 2008, 32(11):1362-1370. 10.1016/j.cellbi.2008.08.005, 18773965.
29. Nakashima K, de Crombrugghe B. Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet 2003, 19(8):458-466. 10.1016/S0168-9525(03)00176-8, 12902164.
30. Sims NA, Gooi JH. Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption. Semin Cell Dev Biol 2008, 19(5):444-451. 10.1016/j.semcdb.2008.07.016, 18718546.
31. Schindeler A, Little DG. Ras-MAPK signaling in osteogenic differentiation: friend or foe?. J Bone Miner Res 2006, 21(9):1331-1338. 10.1359/jbmr.060603, 16939391.
32. Lou J, Tu Y, Li S, Manske PR. Involvement of ERK in BMP-2 induced osteoblastic differentiation of mesenchymal progenitor cell line C3H10T1/2. Biochem Biophys Res Commun 2000, 268(3):757-762. 10.1006/bbrc.2000.2210, 10679278.
33. Celil AB, Campbell PG. BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways. J Biol Chem 2005, 280(36):31353-31359. 10.1074/jbc.M503845200, 16000303.
34. Jaiswal RK, Jaiswal N, Bruder SP, Mbalaviele G, Marshak DR, Pittenger MF. Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase. J Biol Chem 2000, 275(13):9645-9652. 10.1074/jbc.275.13.9645, 10734116.
35. Xiao G, Jiang D, Thomas P, Benson MD, Guan K, Karsenty G, et al. MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. J Biol Chem 2000, 275(6):4453-4459. 10.1074/jbc.275.6.4453, 10660618.
36. Balcerzak M, Hamade E, Zhang L, Pikula S, Azzar G, Radisson J, et al. The roles of annexins and alkaline phosphatase in mineralization process. Acta Biochim Pol 2003, 50(4):1019-1038.
37. Gimble JM, Katz AJ, Bunnell BA. Adipose-derived stem cells for regenerative medicine. Circ Res 2007, 100(9):1249-1260. 10.1161/01.RES.0000265074.83288.09, 17495232.
38. Matsuo K, Irie N. Osteoclast-osteoblast communication. Arch Biochem Biophys 2008, 473(2):201-209. 10.1016/j.abb.2008.03.027, 18406338.
39. Bekker PJ, Holloway D, Nakanishi A, Arrighi M, Leese PT, Dunstan CR. The effect of a single dose of osteoprotegerin in postmenopausal women. J Bone Miner Res 2001, 16(2):348-360. 10.1359/jbmr.2001.16.2.348, 11204435.