메뉴 건너뛰기




Volumn 27, Issue 3-4, 2011, Pages 243-250

Activation of FGF receptors is a new mechanism by which strontium ranelate induces osteoblastic cell growth

Author keywords

Calcium sensing receptor; Cation sensing mechanism; Fibroblast growth factor signaling; Growth; MC3T3 E1; Primary calvaria derived osteoblast; Strontium ranelate

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; CALCIUM SENSING RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 4; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NEOMYCIN; PROTEIN TYROSINE KINASE INHIBITOR; STRONTIUM RANELATE;

EID: 79953777185     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000327950     Document Type: Article
Times cited : (46)

References (32)
  • 1
    • 3142760492 scopus 로고    scopus 로고
    • Strontium ranelate: New therapeutic agent for postmenopausal osteoporosis
    • Paris
    • Meunier PJ: [strontium ranelate: New therapeutic agent for postmenopausal osteoporosis]. Med Sci (Paris) 2004;20:631-633.
    • (2004) Med Sci , vol.20 , pp. 631-633
    • Meunier, P.J.1
  • 2
    • 26044479221 scopus 로고    scopus 로고
    • Strontium ranelate: A new treatment for postmenopausal osteoporosis with a dual mode of action
    • Reginster JY, Sarlet N, Lejeune E, Leonori L: Strontium ranelate: A new treatment for postmenopausal osteoporosis with a dual mode of action. Curr Osteoporos Rep 2005;3:30-34.
    • (2005) Curr Osteoporos Rep , vol.3 , pp. 30-34
    • Reginster, J.Y.1    Sarlet, N.2    Lejeune, E.3    Leonori, L.4
  • 3
    • 0034815044 scopus 로고    scopus 로고
    • Mechanisms of action and therapeutic potential of strontium in bone
    • DOI 10.1007/s002230010055
    • Marie PJ, Ammann P, Boivin G, Rey C: Mechanisms of action and therapeutic potential of strontium in bone. Calcif Tissue Int 2001;69:121-129. (Pubitemid 32912229)
    • (2001) Calcified Tissue International , vol.69 , Issue.3 , pp. 121-129
    • Marie, P.J.1    Ammann, P.2    Boivin, G.3    Rey, C.4
  • 4
    • 0030176233 scopus 로고    scopus 로고
    • The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro
    • DOI 10.1016/8756-3282(96)00080-4
    • Canalis E, Hott M, Deloffre P, Tsouderos Y, Marie PJ: The divalent strontium salt s12911 enhances bone cell replication and bone formation in vitro. Bone 1996;18:517-523. (Pubitemid 26257871)
    • (1996) Bone , vol.18 , Issue.6 , pp. 517-523
    • Canalis, E.1    Hott, M.2    Deloffre, P.3    Tsouderos, Y.4    Marie, P.J.5
  • 5
    • 36049018715 scopus 로고    scopus 로고
    • Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength
    • DOI 10.1359/jbmr.070607
    • Ammann P, Badoud I, Barraud S, Dayer R, Rizzoli R: Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength. J Bone Miner Res 2007;22:1419-1425. (Pubitemid 351339686)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.9 , pp. 1419-1425
    • Ammann, P.1    Badoud, I.2    Barraud, S.3    Dayer, R.4    Rizzoli, R.5
  • 6
    • 17644382533 scopus 로고    scopus 로고
    • Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats
    • DOI 10.1359/JBMR.040906
    • Ammann P, Shen V, Robin B, Mauras Y, Bonjour JP, Rizzoli R: Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. J Bone Miner Res 2004;19:2012-2020. (Pubitemid 41103416)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.12 , pp. 2012-2020
    • Ammann, P.1    Shen, V.2    Robin, B.3    Mauras, Y.4    Bonjour, J.-P.5    Rizzoli, R.6
  • 7
    • 0037118899 scopus 로고    scopus 로고
    • In vitro effects of s12911-2 on osteoclast function and bone marrow macrophage differentiation
    • Baron R, Tsouderos Y: In vitro effects of s12911-2 on osteoclast function and bone marrow macrophage differentiation. Eur J Pharmacol 2002;450:11-17.
    • (2002) Eur J Pharmacol , vol.450 , pp. 11-17
    • Baron, R.1    Tsouderos, Y.2
  • 8
    • 0027316220 scopus 로고
    • An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats
    • Marie PJ, Hott M, Modrowski D, De Pollak C, Guillemain J, Deloffre P, Tsouderos Y: An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 1993;8:607-615. (Pubitemid 23127921)
    • (1993) Journal of Bone and Mineral Research , vol.8 , Issue.5 , pp. 607-615
    • Marie, P.J.1    Hott, M.2    Modrowski, D.3    De Pollak, C.4    Guillemain, J.5    Deloffre, P.6    Tsouderos, Y.7
  • 10
    • 37349123534 scopus 로고    scopus 로고
    • Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro
    • DOI 10.1016/j.bone.2007.08.043, PII S8756328207006667
    • Bonnelye E, Chabadel A, Saltel F, Jurdic P: Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone 2008;42:129-138. (Pubitemid 350297175)
    • (2008) Bone , vol.42 , Issue.1 , pp. 129-138
    • Bonnelye, E.1    Chabadel, A.2    Saltel, F.3    Jurdic, P.4
  • 13
    • 4644294488 scopus 로고    scopus 로고
    • In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor
    • Coulombe J, Faure H, Robin B, Ruat M: In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor. Biochem Biophys Res Commun 2004;323:1184-1190.
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 1184-1190
    • Coulombe, J.1    Faure, H.2    Robin, B.3    Ruat, M.4
  • 14
    • 34250870142 scopus 로고    scopus 로고
    • The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation
    • DOI 10.1016/j.bcp.2007.04.020, PII S0006295207002602
    • Chattopadhyay N, Quinn SJ, Kifor O, Ye C, Brown EM: The calcium-sensing receptor (car) is involved in strontium ranelate-induced osteoblast proliferation. Biochem Pharmacol 2007;74:438-447. (Pubitemid 46970843)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.3 , pp. 438-447
    • Chattopadhyay, N.1    Quinn, S.J.2    Kifor, O.3    Ye, C.4    Brown, E.M.5
  • 15
    • 72949086648 scopus 로고    scopus 로고
    • Calcium sensing receptor-dependent and - Independent activation of osteoblast replication and survival by strontium ranelate
    • Fromigue O, Hay E, Barbara A, Petrel C, Traiffort E, Ruat M, Marie PJ: Calcium sensing receptor-dependent and - independent activation of osteoblast replication and survival by strontium ranelate. J Cell Mol Med 2009;13,:2189-2199.
    • (2009) J Cell Mol Med , vol.13 , pp. 2189-2199
    • Fromigue, O.1    Hay, E.2    Barbara, A.3    Petrel, C.4    Traiffort, E.5    Ruat, M.6    Marie, P.J.7
  • 16
    • 43149125403 scopus 로고    scopus 로고
    • Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms
    • Caverzasio J: Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms. Bone 2008;42:1131-1136.
    • (2008) Bone , vol.42 , pp. 1131-1136
    • Caverzasio, J.1
  • 17
    • 0022569874 scopus 로고
    • Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations
    • DOI 10.1007/BF02556874
    • Bellows CG, Aubin JE, Heersche JN, Antosz ME: Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif Tissue Int 1986;38:143-154. (Pubitemid 16160917)
    • (1986) Calcified Tissue International , vol.38 , Issue.3 , pp. 143-154
    • Bellows, C.G.1    Aubin, J.E.2    Heersche, H.N.M.3    Antosz, M.E.4
  • 18
    • 0345791533 scopus 로고    scopus 로고
    • Protein Kinase C-independent Activation of Protein Kinase D Is Involved in BMP-2-induced Activation of Stress Mitogen-activated Protein Kinases JNK and p38 and Osteoblastic Cell Differentiation
    • DOI 10.1074/jbc.M308665200
    • Lemonnier J, Ghayor C, Guicheux J, Caverzasio J: Protein kinase c-independent activation of protein kinase d is involved in bmp-2-induced activation of stress mitogen-activated protein kinases jnk and p38 and osteoblastic cell differentiation. J Biol Chem 2004;279:259-264. (Pubitemid 38044823)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.1 , pp. 259-264
    • Lemonnier, J.1    Ghayor, C.2    Guicheux, J.3    Caverzasio, J.4
  • 19
    • 28044463176 scopus 로고    scopus 로고
    • FGF and FGFR signaling in chondrodysplasias and craniosynostosis
    • DOI 10.1002/jcb.20582
    • Marie PJ, Coffin JD, Hurley MM: Fgf and fgfr signaling in chondrodysplasias and craniosynostosis. J Cell Biochem 2005;96:888-896. (Pubitemid 41688715)
    • (2005) Journal of Cellular Biochemistry , vol.96 , Issue.5 , pp. 888-896
    • Marie, P.J.1    Coffin, J.D.2    Hurley, M.M.3
  • 20
    • 18244363907 scopus 로고    scopus 로고
    • The calcium-sensing receptor in normal physiology and pathophysiology: A review
    • DOI 10.1080/10408360590886606
    • Tfelt-Hansen J, Brown EM: The calcium-sensing receptor in normal physiology and pathophysiology: A review. Crit Rev Clin Lab Sci 2005;42:35-70. (Pubitemid 41656709)
    • (2005) Critical Reviews in Clinical Laboratory Sciences , vol.42 , Issue.1 , pp. 35-70
    • Tfelt-Hansen, J.1    Brown, E.M.2
  • 21
    • 0018888487 scopus 로고
    • Effect of fibroblast growth factor on cultured fetal rat calvaria
    • Canalis E, Raisz LG: Effect of fibroblast growth factor on cultured fetal rat calvaria. Metabolism 1980;29:108-114. (Pubitemid 10139549)
    • (1980) Metabolism: Clinical and Experimental , vol.29 , Issue.2 , pp. 108-114
    • Canalis, E.1    Raisz, L.G.2
  • 22
    • 0026050771 scopus 로고
    • Epidermal growth factor attenuates cell proliferation by down-regulating the transforming growth factor-beta receptor in the osteoblastic cell line mc3t3-e1
    • Jikihara H, Ikegami H, Sakata M, Morishige K, Fujita Y, Kurachi H, Miyake A, Tanizawa O, Terakawa N: Epidermal growth factor attenuates cell proliferation by down-regulating the transforming growth factor-beta receptor in the osteoblastic cell line mc3t3-e1. Bone Miner 1991;15:125-135.
    • (1991) Bone Miner , vol.15 , pp. 125-135
    • Jikihara, H.1    Ikegami, H.2    Sakata, M.3    Morishige, K.4    Fujita, Y.5    Kurachi, H.6    Miyake, A.7    Tanizawa, O.8    Terakawa, N.9
  • 23
    • 21744459448 scopus 로고    scopus 로고
    • Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells
    • DOI 10.1002/jcb.20138
    • Mehrotra M, Krane SM, Walters K, Pilbeam C: Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells. J Cell Biochem 2004;93:741-752. (Pubitemid 44264170)
    • (2004) Journal of Cellular Biochemistry , vol.93 , Issue.4 , pp. 741-752
    • Mehrotra, M.1    Krane, S.M.2    Walters, K.3    Pilbeam, C.4
  • 24
    • 0036431919 scopus 로고    scopus 로고
    • Mesenchymal cells potentiate vascular endothelial growth factor-induced angiogenesis in vitro
    • Tille JC, Pepper MS: Mesenchymal cells potentiate vascular endothelial growth factor-induced angiogenesis in vitro. Exp Cell Res 2002;280:179-191.
    • (2002) Exp Cell Res , vol.280 , pp. 179-191
    • Tille, J.C.1    Pepper, M.S.2
  • 25
    • 0001774050 scopus 로고    scopus 로고
    • Fibroblast Growth Factor and Fibroblast Growth Factor Receptor Families in Bone
    • Bilezikian J, Raisz LG, Rodan G. (eds): San Diego, Academic Press
    • Hurley MM, Marie PJ, Florkiewicz RZ: Fibroblast Growth Factor and Fibroblast Growth Factor Receptor Families in Bone: in Bilezikian J, Raisz LG, Rodan G. (eds): Principles of Bone Biology. San Diego, Academic Press, 2002, pp 825-851.
    • (2002) Principles of Bone Biology , pp. 825-851
    • Hurley, M.M.1    Marie, P.J.2    Florkiewicz, R.Z.3
  • 27
    • 0030022555 scopus 로고    scopus 로고
    • Copper and calcium binding motifs in the extracellular domains of fibroblast growth factor receptors
    • DOI 10.1074/jbc.271.7.3343
    • Patstone G, Maher P: Copper and calcium binding motifs in the extracellular domains of fibroblast growth factor receptors. J Biol Chem 1996;271:3343-3346. (Pubitemid 26065635)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.7 , pp. 3343-3346
    • Patstone, G.1    Maher, P.2
  • 29
    • 12344278405 scopus 로고    scopus 로고
    • FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity
    • DOI 10.1242/jcs.01519
    • Li X, Brunton VG, Burgar HR, Wheldon LM, Heath JK: Frs2-dependent src activation is required for fibroblast growth factor receptor-induced phosphorylation of sprouty and suppression of erk activity. J Cell Sci 2004;117:6007-6017. (Pubitemid 40123967)
    • (2004) Journal of Cell Science , vol.117 , Issue.25 , pp. 6007-6017
    • Li, X.1    Brunton, V.G.2    Burgar, H.R.3    Wheldon, L.M.4    Heath, J.K.5
  • 30
    • 0035138936 scopus 로고    scopus 로고
    • Revelations of the RYK receptor
    • DOI 10.1002/1521-1878(200101)23:1<34::AID-BIES1005>3.0.CO;2-D
    • Halford MM, Stacker SA: Revelations of the ryk receptor. Bioessays 2001;23:34-45. (Pubitemid 32100499)
    • (2001) BioEssays , vol.23 , Issue.1 , pp. 34-45
    • Halford, M.M.1    Stacker, S.A.2
  • 31
    • 3242810659 scopus 로고    scopus 로고
    • A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium
    • DOI 10.1359/JBMR.040114
    • Pi M, Quarles LD: A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium. J Bone Miner Res 2004;19:862-869. (Pubitemid 41094398)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.5 , pp. 862-869
    • Pi, M.1    Quarles, L.D.2
  • 32
    • 0031685091 scopus 로고    scopus 로고
    • 2+ (o))-Sensing receptor and its agonists stimulate chemotaxis and proliferation of MC3T3-E1 cells
    • DOI 10.1359/jbmr.1998.13.10.1530
    • Yamaguchi T, Chattopadhyay N, Kifor O, Butters RR Jr, Sugimoto T, Brown EM: Mouse osteoblastic cell line (mc3t3-e1) expresses extracellular calcium (ca2+o)-sensing receptor and its agonists stimulate chemotaxis and proliferation of mc3t3-e1 cells. J Bone Miner Res 1998;13:1530-1538. (Pubitemid 28465293)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.10 , pp. 1530-1538
    • Yamaguchi, T.1    Chattopadhyay, N.2    Kifor, O.3    Butters Jr., R.R.4    Sugimoto, T.5    Brown, E.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.