Rho-kinase regulates thrombin-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts

International Journal of Molecular Medicine

Volumn 28, Issue 4, 2011, Pages 653-658

  Kato, Kenji ^a,b   Otsuka, Takanobu ^a   Matsushima Nishiwaki, Rie ^b   Natsume, Hideo ^a,b   Kozawa, Osamu ^b   Tokuda, Haruhiko ^b,c  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Interleukin 6; Mitogen activated protein kinase; Osteoblast; Rho kinase; Thrombin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BIRB 0796; ENZYME INHIBITOR; FASUDIL; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 10; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN PHOSPHATASE TARGETING 1; PHOSPHATASE; RHO KINASE; STRESS ACTIVATED PROTEIN KINASE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS;

ANIMALS; BLOTTING, WESTERN; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-6; MAP KINASE KINASE 4; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOSIN-LIGHT-CHAIN KINASE; OSTEOBLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RHO-ASSOCIATED KINASES; THROMBIN;

EID: 79960749010     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.747     Document Type: Article

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