Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase

Science

Volumn 272, Issue 5266, 1996, Pages 1347-1349

  Wang, XiaoZhong ^a   Ron, David ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLECARBOXYLIC ACID 2 (1 PIPERIDINYL)ETHYL ESTER; MITOGEN ACTIVATED PROTEIN KINASE; SERINE; TRANSCRIPTION FACTOR;

ADIPOSE TISSUE CELL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STRESS; TRANSCRIPTION INITIATION;

EID: 0029938805     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.272.5266.1347     Document Type: Article

References (34)

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34. Supported by U. S. Public Health Service award DK 47119 and by a grant from the Arthritis Foundation. D.R. is a Pew Scholar in the Biomedical Sciences. We thank E. Skolnik and M, Mohammadi (New York University) for advice and the following colleagues for reagents: J. C. Lee (Smithkline Beecham Pharmaceuticals), SB203580; R. J. Ulevitch (Scripps Clinic) and R. J. Davis (U. Mass, Worcester), p38 expression plasmid; L. I. Zon (Children's Hospital, Boston), SAPK-1β expression plasmid; D. J. Templeton (Case Western), activated MEK expression plasmid; and M. Karin (UCSD) and Y. Ben Neriah (Haddash, Jerusalem), GST-Jun expression plasmid.