Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: Roles of extracellular matrix, Shc, and mitogen-activated protein kinase

Journal of Bone and Mineral Research

Volumn 23, Issue 7, 2008, Pages 1140-1149

  Lee, Ding Yu ^a   Yeh, Chiuan Ren ^b   Chang, Shun Fu ^a   Lee, Pei Ling ^a   Chien, Shu ^c   Cheng, Cheng Kung ^b   Chiu, Jeng Jiann ^a,b  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Extracellular matrix; Gene expression; Integrins; Mechanotransduction; Shear stress

Indexed keywords

BETA1 INTEGRIN; COLLAGEN TYPE 1; CYCLOOXYGENASE 2; EARLY GROWTH RESPONSE FACTOR 1; FIBRONECTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTEGRIN; LAMININ; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOPONTIN; PROTEIN C FOS; PROTEIN SHC; STRESS ACTIVATED PROTEIN KINASE; VITRONECTIN RECEPTOR;

ARTICLE; CONTROLLED STUDY; COX 2 GENE; EGR 1 GENE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION REGULATION; GENE INDUCTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OPN GENE; OSSIFICATION; OSTEOBLAST; SHEAR STRESS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BASE SEQUENCE; BLOTTING, WESTERN; BONE DEVELOPMENT; CELL LINE; DNA PRIMERS; EXTRACELLULAR MATRIX; HUMANS; IMMUNOPRECIPITATION; INTEGRINS; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOBLASTS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 46249124836     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.080302     Document Type: Article

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