Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 10, 2009, Pages 1485-1495

  Liu, Lin ^a   Channavajhala, Padma L ^a   Rao, Vikram R ^a   Moutsatsos, Ioannis ^a   Wu, Leeying ^a   Zhang, Yuhua ^a   Lin, Lih ling ^a   Qiu, Yongchang ^a  

^a Wyeth ^*  (United States)

Author keywords

Kinase suppressor of Ras (KSR); MAPK signaling; Mass spectrometry; Proteomics; Scaffold protein signaling complex

Indexed keywords

A RAF KINASE; I KAPPA B KINASE; INSULIN; KINASE SUPPRESSOR OF RAS 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; RAF PROTEIN; SCAFFOLD PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL STIMULATION; CONTROLLED STUDY; CROSS LINKING; DNA REPAIR; DNA SYNTHESIS; EMBRYO; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME SPECIFICITY; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; CELL LINE; HUMANS; IMMUNOPRECIPITATION; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; PROTEOMICS; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69649098398     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.06.016     Document Type: Article

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