메뉴 건너뛰기




Volumn 1116, Issue , 2007, Pages 196-207

Transcriptional regulation of osteoblasts

Author keywords

Bone; Extracellular matrix; Osteoblast; RUNX2; Transcription

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; SERINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 37249028142     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1402.081     Document Type: Conference Paper
Times cited : (174)

References (28)
  • 1
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation [see comments]
    • DUCY, P. et al. 1997. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation [see comments]. Cell 89: 747-754.
    • (1997) Cell , vol.89 , pp. 747-754
    • DUCY, P.1
  • 2
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • NAKASHIMA, K. et al. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108: 17-29.
    • (2002) Cell , vol.108 , pp. 17-29
    • NAKASHIMA, K.1
  • 3
    • 11144357428 scopus 로고    scopus 로고
    • ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome
    • YANG, X. et al. 2004. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell 117: 387-398.
    • (2004) Cell , vol.117 , pp. 387-398
    • YANG, X.1
  • 4
    • 34447500094 scopus 로고    scopus 로고
    • Dominance of SOX9 function over RUNX2 during skeletogenesis
    • ZHOU, G. et al. 2006. Dominance of SOX9 function over RUNX2 during skeletogenesis. Proc. Natl. Acad. Sci. USA 103: 19004-19009.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 19004-19009
    • ZHOU, G.1
  • 5
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • OTTO, F. et al. 1997. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89: 765-771.
    • (1997) Cell , vol.89 , pp. 765-771
    • OTTO, F.1
  • 6
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • KOMORI, T. et al. 1997. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89: 755-764.
    • (1997) Cell , vol.89 , pp. 755-764
    • KOMORI, T.1
  • 7
    • 0032483809 scopus 로고    scopus 로고
    • Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor
    • XIAO, G. et al. 1998. Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor. J. Biol. Chem. 273: 32988-32994.
    • (1998) J. Biol. Chem , vol.273 , pp. 32988-32994
    • XIAO, G.1
  • 8
    • 24744451966 scopus 로고    scopus 로고
    • Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene
    • ROCA, H. et al. 2005. Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene. J. Biol. Chem. 280: 30845-30855.
    • (2005) J. Biol. Chem , vol.280 , pp. 30845-30855
    • ROCA, H.1
  • 9
    • 2942659322 scopus 로고    scopus 로고
    • Oncogenic potential of the RUNX gene family: 'overview'
    • ITO, Y. 2004. Oncogenic potential of the RUNX gene family: 'overview'. Oncogene 23: 4198-4208.
    • (2004) Oncogene , vol.23 , pp. 4198-4208
    • ITO, Y.1
  • 10
    • 24744458827 scopus 로고    scopus 로고
    • Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression
    • XIAO, G. et al. 2005. Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. J. Biol. Chem. 280: 30689-30696.
    • (2005) J. Biol. Chem , vol.280 , pp. 30689-30696
    • XIAO, G.1
  • 11
    • 1242339671 scopus 로고    scopus 로고
    • Parathyroid hormone induction of the osteocalcin gene. Requirement for an osteoblast-specific element 1 sequence in the promoter and involvement of multiple-signaling pathways
    • JIANG, D. et al. 2004. Parathyroid hormone induction of the osteocalcin gene. Requirement for an osteoblast-specific element 1 sequence in the promoter and involvement of multiple-signaling pathways. J. Biol. Chem. 279: 5329-5337.
    • (2004) J. Biol. Chem , vol.279 , pp. 5329-5337
    • JIANG, D.1
  • 12
    • 20144365699 scopus 로고    scopus 로고
    • Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription
    • AFZAL, F. et al. 2005. Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. J. Cell. Physiol. 204: 63-72.
    • (2005) J. Cell. Physiol , vol.204 , pp. 63-72
    • AFZAL, F.1
  • 13
    • 12144288066 scopus 로고    scopus 로고
    • A twist code determines the onset of osteoblast differentiation
    • BIALEK, P. et al. 2004. A twist code determines the onset of osteoblast differentiation. Dev. Cell. 6: 423-435.
    • (2004) Dev. Cell , vol.6 , pp. 423-435
    • BIALEK, P.1
  • 14
    • 9144235404 scopus 로고    scopus 로고
    • The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1
    • IMAI, Y. et al. 2004. The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1. Mol. Cell Biol. 24: 1033-1043.
    • (2004) Mol. Cell Biol , vol.24 , pp. 1033-1043
    • IMAI, Y.1
  • 15
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • HYNES, R.O. 2002. Integrins: bidirectional, allosteric signaling machines. Cell 110: 673-687.
    • (2002) Cell , vol.110 , pp. 673-687
    • HYNES, R.O.1
  • 16
    • 0035918140 scopus 로고    scopus 로고
    • Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts
    • YOU, J. et al. 2001. Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J. Biol. Chem. 276: 13365-13371.
    • (2001) J. Biol. Chem , vol.276 , pp. 13365-13371
    • YOU, J.1
  • 17
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification [see comment]
    • ENGLER, A.J. et al. 2006. Matrix elasticity directs stem cell lineage specification [see comment]. Cell 126: 677-689.
    • (2006) Cell , vol.126 , pp. 677-689
    • ENGLER, A.J.1
  • 18
    • 0026737469 scopus 로고
    • The role of ascorbic acid in mesenchymal differentiation
    • FRANCESCHI, R.T. 1992. The role of ascorbic acid in mesenchymal differentiation. Nutr. Rev. 50: 65-70.
    • (1992) Nutr. Rev , vol.50 , pp. 65-70
    • FRANCESCHI, R.T.1
  • 19
    • 0030996530 scopus 로고    scopus 로고
    • Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: Requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence
    • XIAO, G. et al. 1997. Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblasts: requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence. Mol. Endocrinol. 11: 1103-1113.
    • (1997) Mol. Endocrinol , vol.11 , pp. 1103-1113
    • XIAO, G.1
  • 20
    • 0034635477 scopus 로고    scopus 로고
    • MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1
    • XIAO, G. et al. 2000. MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. J. Biol. Chem. 275: 4453-4459.
    • (2000) J. Biol. Chem , vol.275 , pp. 4453-4459
    • XIAO, G.1
  • 21
    • 0032515043 scopus 로고    scopus 로고
    • Functional hierarchy between two OSE2 elements in the control of osteocalcin gene expression in vivo
    • FRENDO, J.L. et al. 1998. Functional hierarchy between two OSE2 elements in the control of osteocalcin gene expression in vivo. J. Biol. Chem. 273: 30509-30516.
    • (1998) J. Biol. Chem , vol.273 , pp. 30509-30516
    • FRENDO, J.L.1
  • 22
    • 0037184027 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2
    • XIAO, G. et al. 2002. Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2. J. Biol. Chem. 277: 36181-36187.
    • (2002) J. Biol. Chem , vol.277 , pp. 36181-36187
    • XIAO, G.1
  • 23
    • 0037414760 scopus 로고    scopus 로고
    • The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2
    • KIM, H.J. et al. 2003. The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2. J. Biol. Chem. 278: 319-326.
    • (2003) J. Biol. Chem , vol.278 , pp. 319-326
    • KIM, H.J.1
  • 24
    • 0037192760 scopus 로고    scopus 로고
    • Superoxide mediates shock wave induction of ERK-dependent osteogenic transcription factor (CBFA1) and mesenchymal cell differentiation toward osteoprogenitors
    • WANG, F.S. et al. 2002. Superoxide mediates shock wave induction of ERK-dependent osteogenic transcription factor (CBFA1) and mesenchymal cell differentiation toward osteoprogenitors. J. Biol. Chem. 277: 10931-10937.
    • (2002) J. Biol. Chem , vol.277 , pp. 10931-10937
    • WANG, F.S.1
  • 25
    • 0037189499 scopus 로고    scopus 로고
    • The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells
    • ZIROS, P.G. et al. 2002. The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells. J. Biol. Chem. 277: 23934-23941.
    • (2002) J. Biol. Chem , vol.277 , pp. 23934-23941
    • ZIROS, P.G.1
  • 26
    • 34547906444 scopus 로고    scopus 로고
    • Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts
    • KANNO, T. et al. 2007. Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts. J. Cell. Biochem. 101: 1266-1277.
    • (2007) J. Cell. Biochem , vol.101 , pp. 1266-1277
    • KANNO, T.1
  • 27
    • 33847375078 scopus 로고    scopus 로고
    • Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development
    • GE, C. et al. 2007. Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J. Cell. Biol. 176: 709-718.
    • (2007) J. Cell. Biol , vol.176 , pp. 709-718
    • GE, C.1
  • 28
    • 0037241624 scopus 로고    scopus 로고
    • Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation
    • FRANCESCHI, R.T. et al. 2003. Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation. Connect. Tissue Res. 44(Suppl 1): 109-116.
    • (2003) Connect. Tissue Res , vol.44 , Issue.SUPPL. 1 , pp. 109-116
    • FRANCESCHI, R.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.