The Secreted Protein ANGPTL2 Promotes Metastasis of Osteosarcoma Cells Through Integrin α5β1, p38 MAPK, and Matrix Metalloproteinases

Science Signaling

Volumn 7, Issue 309, 2014, Pages

  Odagiri, Haruki ^a   Kadomatsu, Tsuyoshi ^a   Endo, Motoyoshi ^a   Motoyoshi, Tetsuro ^a   Morioka, Masaki Suimye ^b   Fukuhara, Shigetomo ^c   Miyamoto, Takeshi ^d   Kobayashi, Eisuke ^d   Miyata, Keishi ^a   Aoi, Jun ^a   Horiguchi, Haruki ^a   Nishimura, Naotaka ^a   Terada, Kazutoyo ^a   Yakushiji, Toshitake ^a   Manabe, Ichiro ^b   Mochizuki, Naoki ^c   Mizuta, Hiroshi ^a   Oike, Yuichi ^a,e  

^a KUMAMOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d KEIO UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN LIKE PROTEIN 2; COLLAGENASE 3; DNA; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEINASE; TOLLOID LIKE 1 PROTEASE; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; ANGIOPOIETIN; ANGPTL2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL MIGRATION; CONTROLLED STUDY; DEMETHYLATION; DISTANT METASTASIS FREE SURVIVAL; DNA METHYLATION; ENZYME RELEASE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; LUNG METASTASIS; MOUSE; MOUSE MODEL; NONHUMAN; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TIME; TUMOR BIOPSY; TUMOR INVASION; TUMOR MICROENVIRONMENT; TUMOR PROMOTION; TUMOR XENOGRAFT; ANIMAL; BONE TUMOR; ENZYMOLOGY; GENETICS; METABOLISM; METASTASIS; NEOVASCULARIZATION (PATHOLOGY); OSTEOSARCOMA; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; XENOGRAFT;

ANGIOPOIETINS; ANIMALS; BONE NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; HETEROGRAFTS; HUMANS; INTEGRIN ALPHA5BETA1; MATRIX METALLOPROTEINASES; MICE; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; OSTEOSARCOMA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; TUMOR MICROENVIRONMENT;

EID: 84893040697     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004612     Document Type: Article

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