Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway

Phytotherapy Research

Volumn 25, Issue 11, 2011, Pages 1700-1706

  Niu, Yinbo ^a   Li, Yuhua ^b   Huang, Haitao ^b   Kong, Xianghe ^a   Zhang, Rong ^b   Liu, Li ^b   Sun, Yang ^b   Wang, Tingmei ^a   Mei, Qibing ^a,b  

^a NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Asperosaponin VI; Bone morphogenetic protein; ERK; Osteoporosis; P38

Indexed keywords

ALKALINE PHOSPHATASE; ASPEROSAPONIN VI; BONE MORPHOGENETIC PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SAPONIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MATURATION; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIPSACACEAE; DIPSACUS ASPER; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; OSSIFICATION; OSTEOBLAST; PHYTOCHEMISTRY; PROTEIN EXPRESSION; RAT;

ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; DIPSACACEAE; MAP KINASE SIGNALING SYSTEM; MICE; OSTEOBLASTS; RATS; SAPONINS;

DIPSACUS;

EID: 80054912384     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3414     Document Type: Article

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