-
1
-
-
0026750213
-
Receptors for the TGF-β family
-
Massague J. Receptors for the TGF-β family. Cell. 1992;69:1067-1070.
-
(1992)
Cell
, vol.69
, pp. 1067-1070
-
-
Massague, J.1
-
2
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana JL, Attisano L, Wieser R, Ventura F, Massague J. Mechanism of activation of the TGF-β receptor. Nature. 1994;370:341-347.
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massague, J.5
-
3
-
-
34250019537
-
Bone: Formation by autoinduction
-
Urist MR. Bone: formation by autoinduction. Science. 1965;150:893-899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
4
-
-
0038682002
-
Mechanisms of TGF-β signaling from cell membrane to the nucleus
-
Shi Y, Massague J. Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell. 2003;113:685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
5
-
-
2342516135
-
Molecular recognition of BMP-2 and BMP receptor IA
-
Keller S, Nickel J, Zhang JL, Sebald W, Mueller TD. Molecular recognition of BMP-2 and BMP receptor IA. Nat Struct Mol Biol. 2004;11:481-488.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 481-488
-
-
Keller, S.1
Nickel, J.2
Zhang, J.L.3
Sebald, W.4
Mueller, T.D.5
-
6
-
-
0034460683
-
Identification of the ligand-binding site of the BMP type IA receptor for BMP-4
-
Hatta T, Konishi H, Katoh E, et al. Identification of the ligand-binding site of the BMP type IA receptor for BMP-4. Biopolymers. 2000;55:399-406.
-
(2000)
Biopolymers
, vol.55
, pp. 399-406
-
-
Hatta, T.1
Konishi, H.2
Katoh, E.3
-
7
-
-
0026721147
-
The bone morphogenetic protein family and osteogenesis
-
Wozney JM. The bone morphogenetic protein family and osteogenesis. Mol Reprod Dev. 1992;32:160-167.
-
(1992)
Mol Reprod Dev
, vol.32
, pp. 160-167
-
-
Wozney, J.M.1
-
9
-
-
33646348736
-
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
-
Shore EM, Xu M, Feldman GJ, et al. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat Genet. 2006;38:525-527.
-
(2006)
Nat Genet
, vol.38
, pp. 525-527
-
-
Shore, E.M.1
Xu, M.2
Feldman, G.J.3
-
10
-
-
57349171954
-
BMP type I receptor inhibition reduces heterotopic [corrected] ossification
-
Yu PB, Deng DY, Lai CS, et al. BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med. 2008;14:1363-1369.
-
(2008)
Nat Med
, vol.14
, pp. 1363-1369
-
-
Yu, P.B.1
Deng, D.Y.2
Lai, C.S.3
-
11
-
-
0029850112
-
Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
-
Zhang H, Bradley A. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development. 1996;122:2977-2986.
-
(1996)
Development
, vol.122
, pp. 2977-2986
-
-
Zhang, H.1
Bradley, A.2
-
12
-
-
0029149656
-
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
-
Winnier G, Blessing M, Labosky PA, Hogan BL. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 1995;9:2105-2116.
-
(1995)
Genes Dev
, vol.9
, pp. 2105-2116
-
-
Winnier, G.1
Blessing, M.2
Labosky, P.A.3
Hogan, B.L.4
-
13
-
-
6244256053
-
Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis
-
Mishina Y, Suzuki A, Ueno N, Behringer RR. Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev. 1995;9:3027-3037. (Pubitemid 26018138)
-
(1995)
Genes and Development
, vol.9
, Issue.24
, pp. 3027-3037
-
-
Mishina, Y.1
Suzuki, A.2
Ueno, N.3
Behringer, R.R.4
-
14
-
-
59149096379
-
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
-
Kamiya N, Ye L, Kobayashi T, et al. BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008;135:3801-3811.
-
(2008)
Development
, vol.135
, pp. 3801-3811
-
-
Kamiya, N.1
Ye, L.2
Kobayashi, T.3
-
15
-
-
56749149761
-
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass
-
Kamiya N, Ye L, Kobayashi T, et al. Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res. 2008;23:2007-2017.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 2007-2017
-
-
Kamiya, N.1
Ye, L.2
Kobayashi, T.3
-
16
-
-
0037673933
-
Control of osteoblast function and regulation of bone mass
-
Harada S, Rodan GA. Control of osteoblast function and regulation of bone mass. Nature. 2003;423:349-355.
-
(2003)
Nature
, vol.423
, pp. 349-355
-
-
Harada, S.1
Rodan, G.A.2
-
19
-
-
33644828002
-
A Wnt canon orchestrating osteoblastogenesis
-
Hartmann C. A Wnt canon orchestrating osteoblastogenesis. Trends Cell Biol. 2006;16:151-158.
-
(2006)
Trends Cell Biol
, vol.16
, pp. 151-158
-
-
Hartmann, C.1
-
20
-
-
33745034435
-
Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway
-
Glass DA 2nd, Karsenty G. Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway. Curr Top Dev Biol. 2006;73:43-84.
-
(2006)
Curr Top Dev Biol
, vol.73
, pp. 43-84
-
-
Glass II, D.A.1
Karsenty, G.2
-
21
-
-
0142241118
-
BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop
-
Rawadi G, Vayssiere B, Dunn F, Baron R, Roman-Roman S. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J Bone Miner Res. 2003;18:1842-1853.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 1842-1853
-
-
Rawadi, G.1
Vayssiere, B.2
Dunn, F.3
Baron, R.4
Roman-Roman, S.5
-
22
-
-
0037474465
-
Activated β-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2-mediated signal transduction
-
Bain G, Muller T, Wang X, Papkoff J. Activated β-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2-mediated signal transduction. Biochem Biophys Res Commun. 2003;301:84-91.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 84-91
-
-
Bain, G.1
Muller, T.2
Wang, X.3
Papkoff, J.4
-
23
-
-
17144373190
-
β-Catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation
-
Mbalaviele G, Sheikh S, Stains JP, et al. β-Catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation. J Cell Biochem. 2005;94:403-418.
-
(2005)
J Cell Biochem
, vol.94
, pp. 403-418
-
-
Mbalaviele, G.1
Sheikh, S.2
Stains, J.P.3
-
24
-
-
13244298422
-
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins
-
Winkler DG, Sutherland MS, Ojala E, et al. Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins. J Biol Chem. 2005;280:2498-2502.
-
(2005)
J Biol Chem
, vol.280
, pp. 2498-2502
-
-
Winkler, D.G.1
Sutherland, M.S.2
Ojala, E.3
-
25
-
-
27844541752
-
Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts
-
Nakashima A, Katagiri T, Tamura M. Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts. J Biol Chem. 2005;280:37660-37668.
-
(2005)
J Biol Chem
, vol.280
, pp. 37660-37668
-
-
Nakashima, A.1
Katagiri, T.2
Tamura, M.3
-
26
-
-
33745671494
-
The role of growth factors and related agents in accelerating fracture healing
-
Simpson AH, Mills L, Noble B. The role of growth factors and related agents in accelerating fracture healing. J Bone Joint Surg Br. 2006;88:701-705.
-
(2006)
J Bone Joint Surg Br
, vol.88
, pp. 701-705
-
-
Simpson, A.H.1
Mills, L.2
Noble, B.3
-
27
-
-
0036193068
-
Generation of Bmpr/Alk3 conditional knockout mice
-
Mishina Y, Hanks MC, Miura S, Tallquist MD, Behringer RR. Generation of Bmpr/Alk3 conditional knockout mice. Genesis. 2002;32:69-72.
-
(2002)
Genesis
, vol.32
, pp. 69-72
-
-
Mishina, Y.1
Hanks, M.C.2
Miura, S.3
Tallquist, M.D.4
Behringer, R.R.5
-
28
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999;21:70-71.
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
29
-
-
0032718124
-
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
-
DasGupta R, Fuchs E. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development. 1999;126:4557-4568.
-
(1999)
Development
, vol.126
, pp. 4557-4568
-
-
DasGupta, R.1
Fuchs, E.2
-
30
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(t)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(t)) method. Methods. 2001;25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
31
-
-
9644270295
-
Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells
-
Fujita N, Kajita M, Taysavang P, Wade PA. Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells. Mol Endocrinol. 2004;18:2937-2949.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2937-2949
-
-
Fujita, N.1
Kajita, M.2
Taysavang, P.3
Wade, P.A.4
-
32
-
-
37249010753
-
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
-
Yu PB, Hong CC, Sachidanandan C, et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2008;4:33-41.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 33-41
-
-
Yu, P.B.1
Hong, C.C.2
Sachidanandan, C.3
-
33
-
-
20344398197
-
Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling
-
Ai M, Holmen SL, Van Hul W, Williams BO, Warman ML. Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. Mol Cell Biol. 2005;25:4946-4955.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4946-4955
-
-
Ai, M.1
Holmen, S.L.2
Van Hul, W.3
Williams, B.O.4
Warman, M.L.5
-
34
-
-
25144448701
-
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
-
Li X, Liu P, Liu W, et al. Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet. 2005;37:945-952.
-
(2005)
Nat Genet
, vol.37
, pp. 945-952
-
-
Li, X.1
Liu, P.2
Liu, W.3
-
35
-
-
0037118279
-
Regulation of bone formation and vision by LRP5
-
Patel MS, Karsenty G. Regulation of bone formation and vision by LRP5. N Engl J Med. 2002;346:1572-1574.
-
(2002)
N Engl J Med
, vol.346
, pp. 1572-1574
-
-
Patel, M.S.1
Karsenty, G.2
-
36
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
Li X, Zhang Y, Kang H, et al. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem. 2005;280:19883-19887.
-
(2005)
J Biol Chem
, vol.280
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
-
37
-
-
22844445934
-
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
-
Semenov M, Tamai K, He X. SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem. 2005;280:26770-26775.
-
(2005)
J Biol Chem
, vol.280
, pp. 26770-26775
-
-
Semenov, M.1
Tamai, K.2
He, X.3
-
38
-
-
2342529836
-
The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice
-
Bodine PV, Zhao W, Kharode YP, et al. The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice. Mol Endocrinol. 2004;18:1222-1237.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 1222-1237
-
-
Bodine, P.V.1
Zhao, W.2
Kharode, Y.P.3
-
39
-
-
0032994043
-
Signal transduction by bone morphogenetic protein receptors: Functional roles of Smad proteins
-
DOI 10.1016/S8756-3282(99)00113-1, PII S8756328299001131
-
Miyazono K. Signal transduction by bone morphogenetic protein receptors: functional roles of Smad proteins. Bone. 1999;25:91-93. (Pubitemid 29322068)
-
(1999)
Bone
, vol.25
, Issue.1
, pp. 91-93
-
-
Miyazono, K.1
-
40
-
-
0032718990
-
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation
-
Fujii M, Takeda K, Imamura T, et al. Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation. Mol Biol Cell. 1999;10:3801-3813.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3801-3813
-
-
Fujii, M.1
Takeda, K.2
Imamura, T.3
-
41
-
-
48549093346
-
Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/BMP signaling during tooth and palate development
-
Xu X, Han J, Ito Y, Bringas P Jr, Deng C, Chai Y. Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/BMP signaling during tooth and palate development. Dev Cell. 2008;15:322-329.
-
(2008)
Dev Cell
, vol.15
, pp. 322-329
-
-
Xu, X.1
Han, J.2
Ito, Y.3
Bringas Jr., P.4
Deng, C.5
Chai, Y.6
-
42
-
-
3042778695
-
A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways
-
Zuzarte-Luis V, Montero JA, Rodriguez-Leon J, Merino R, Rodriguez-Rey JC, Hurle JM. A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways. Dev Biol. 2004;272:39-52.
-
(2004)
Dev Biol
, vol.272
, pp. 39-52
-
-
Zuzarte-Luis, V.1
Montero, J.A.2
Rodriguez-Leon, J.3
Merino, R.4
Rodriguez-Rey, J.C.5
Hurle, J.M.6
-
43
-
-
50049127055
-
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
-
Tseng YH, Kokkotou E, Schulz TJ, et al. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature. 2008;454:1000-1004.
-
(2008)
Nature
, vol.454
, pp. 1000-1004
-
-
Tseng, Y.H.1
Kokkotou, E.2
Schulz, T.J.3
-
44
-
-
63849189600
-
P38-Mitogen-activated protein kinase stimulated steroidogenesis in granulosa cell-oocyte cocultures: Role of bone morphogenetic proteins 2 and 4
-
Inagaki K, Otsuka F, Miyoshi T, et al. p38-Mitogen-activated protein kinase stimulated steroidogenesis in granulosa cell-oocyte cocultures: role of bone morphogenetic proteins 2 and 4. Endocrinology. 2009;150:1921-1930.
-
(2009)
Endocrinology
, vol.150
, pp. 1921-1930
-
-
Inagaki, K.1
Otsuka, F.2
Miyoshi, T.3
-
45
-
-
0346996450
-
Signal transduction of bone morphogenetic protein receptors
-
Nohe A, Keating E, Knaus P, Petersen NO. Signal transduction of bone morphogenetic protein receptors. Cell Signal. 2004;16:291-299.
-
(2004)
Cell Signal
, vol.16
, pp. 291-299
-
-
Nohe, A.1
Keating, E.2
Knaus, P.3
Petersen, N.O.4
-
46
-
-
0035907041
-
β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell. 2001;105:533-545.
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
47
-
-
0037314332
-
Ectodermal Wnt3/β-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge
-
Barrow JR, Thomas KR, Boussadia-Zahui O, et al. Ectodermal Wnt3/β-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003;17:394-409.
-
(2003)
Genes Dev
, vol.17
, pp. 394-409
-
-
Barrow, J.R.1
Thomas, K.R.2
Boussadia-Zahui, O.3
-
48
-
-
4644276225
-
Wnt/β-catenin signaling is sufficient and necessary for synovial joint formation
-
Guo X, Day TF, Jiang X, Garrett-Beal L, Topol L, Yang Y. Wnt/β-catenin signaling is sufficient and necessary for synovial joint formation. Genes Dev. 2004;18:2404-2417.
-
(2004)
Genes Dev
, vol.18
, pp. 2404-2417
-
-
Guo, X.1
Day, T.F.2
Jiang, X.3
Garrett-Beal, L.4
Topol, L.5
Yang, Y.6
-
49
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-β-catenin signaling
-
He XC, Zhang J, Tong WG, et al. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-β-catenin signaling. Nat Genet. 2004;36:1117-1121.
-
(2004)
Nat Genet
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
-
50
-
-
25844524620
-
Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland
-
Dean CH, Miller LA, Smith AN, Dufort D, Lang RA, Niswander LA. Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland. Dev Biol. 2005;286:270-286.
-
(2005)
Dev Biol
, vol.286
, pp. 270-286
-
-
Dean, C.H.1
Miller, L.A.2
Smith, A.N.3
Dufort, D.4
Lang, R.A.5
Niswander, L.A.6
-
51
-
-
33846000938
-
Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion
-
Zhang J, He XC, Tong WG, et al. Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells. 2006;24:2826-2839.
-
(2006)
Stem Cells
, vol.24
, pp. 2826-2839
-
-
Zhang, J.1
He, X.C.2
Tong, W.G.3
-
52
-
-
33846987195
-
Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation
-
Chen Y, Whetstone HC, Youn A, et al. Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. J Biol Chem. 2007;282:526-533.
-
(2007)
J Biol Chem
, vol.282
, pp. 526-533
-
-
Chen, Y.1
Whetstone, H.C.2
Youn, A.3
-
53
-
-
18044399916
-
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse
-
Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, et al. Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Dev Cell. 2001;1:423-434.
-
(2001)
Dev Cell
, vol.1
, pp. 423-434
-
-
Mukhopadhyay, M.1
Shtrom, S.2
Rodriguez-Esteban, C.3
-
54
-
-
0036500653
-
The Wnt antagonist Dickkopf-1 is regulated by BMP signaling and c-Jun and modulates programmed cell death
-
Grotewold L, Ruther U. The Wnt antagonist Dickkopf-1 is regulated by BMP signaling and c-Jun and modulates programmed cell death. EMBO J. 2002;21:966-975.
-
(2002)
EMBO J
, vol.21
, pp. 966-975
-
-
Grotewold, L.1
Ruther, U.2
-
55
-
-
5344234448
-
Sclerostin promotes the apoptosis of human osteoblastic cells: A novel regulation of bone formation
-
Sutherland MK, Geoghegan JC, Yu C, et al. Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation. Bone. 2004;35:828-835.
-
(2004)
Bone
, vol.35
, pp. 828-835
-
-
Sutherland, M.K.1
Geoghegan, J.C.2
Yu, C.3
-
56
-
-
4644227529
-
Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis
-
Ohyama Y, Nifuji A, Maeda Y, Amagasa T, Noda M. Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis. Endocrinology. 2004;145:4685-4692.
-
(2004)
Endocrinology
, vol.145
, pp. 4685-4692
-
-
Ohyama, Y.1
Nifuji, A.2
Maeda, Y.3
Amagasa, T.4
Noda, M.5
-
57
-
-
0035954281
-
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
-
Semenov MV, Tamai K, Brott BK, Kuhl M, Sokol S, He X. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol. 2001;11:951-961.
-
(2001)
Curr Biol
, vol.11
, pp. 951-961
-
-
Semenov, M.V.1
Tamai, K.2
Brott, B.K.3
Kuhl, M.4
Sokol, S.5
He, X.6
-
58
-
-
33646856033
-
Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass
-
Morvan F, Boulukos K, Clement-Lacroix P, et al. Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. J Bone Miner Res. 2006;21:934-945.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 934-945
-
-
Morvan, F.1
Boulukos, K.2
Clement-Lacroix, P.3
-
59
-
-
33748156090
-
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
-
Li J, Sarosi I, Cattley RC, et al. Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone. 2006;39:754-766.
-
(2006)
Bone
, vol.39
, pp. 754-766
-
-
Li, J.1
Sarosi, I.2
Cattley, R.C.3
-
60
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
Tian E, Zhan F, Walker R, et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med. 2003;349:2483-2494.
-
(2003)
N Engl J Med
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
-
61
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
DOI 10.1359/jbmr.080216
-
Li X, Ominsky MS, Niu QT, et al. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res. 2008;23:860-869. (Pubitemid 351768804)
-
(2008)
Journal of Bone and Mineral Research
, vol.23
, Issue.6
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.-T.3
Sun, N.4
Daugherty, B.5
D'Agostin, D.6
Kurahara, C.7
Gao, Y.8
Cao, J.9
Gong, J.10
Asuncion, F.11
Barrero, M.12
Warmington, K.13
Dwyer, D.14
Stolina, M.15
Morony, S.16
Sarosi, I.17
Kostenuik, P.J.18
Lacey, D.L.19
Simonet, W.S.20
Hua, Z.K.21
Paszty, C.22
more..
-
62
-
-
0035282968
-
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
-
Balemans W, Ebeling M, Patel N, et al. Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum Mol Genet. 2001;10:537-543. (Pubitemid 32184286)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.5
, pp. 537-543
-
-
Balemans, W.1
Ebeling, M.2
Patel, N.3
Van Hul, E.4
Olson, P.5
Dioszegi, M.6
Lacza, C.7
Wuyts, W.8
Van Den Ende, J.9
Willems, P.10
Paes-Alves, A.F.11
Hill, S.12
Bueno, M.13
Ramos, F.J.14
Tacconi, P.15
Dikkers, F.G.16
Stratakis, C.17
Lindpaintner, K.18
Vickery, B.19
Foernzler, D.20
Van Hul, W.21
more..
-
63
-
-
0035089781
-
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein
-
DOI 10.1086/318811
-
Brunkow ME, Gardner JC, Van Ness J, et al. Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am J Hum Genet. 2001;68:577-589. (Pubitemid 32202753)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.3
, pp. 577-589
-
-
Brunkow, M.E.1
Gardner, J.C.2
Van Ness, J.3
Paeper, B.W.4
Kovacevich, B.R.5
Proll, S.6
Skonier, J.E.7
Zhao, L.8
Sabo, P.J.9
Fu, Y.-H.10
Alisch, R.S.11
Gillett, L.12
Colbert, T.13
Tacconi, P.14
Galas, D.15
Hamersma, H.16
Beighton, P.17
Mulligan, J.T.18
-
64
-
-
18244403197
-
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
-
Balemans W, Patel N, Ebeling M, et al. Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease. J Med Genet. 2002;39:91-97. (Pubitemid 34146376)
-
(2002)
Journal of Medical Genetics
, vol.39
, Issue.2
, pp. 91-97
-
-
Balemans, W.1
Patel, N.2
Ebeling, M.3
Van Hul, E.4
Wuyts, W.5
Lacza, C.6
Dioszegi, M.7
Dikkers, F.G.8
Hildering, P.9
Willems, P.J.10
Verheij, J.B.G.M.11
Lindpaintner, K.12
Vickery, B.13
Foernzler, D.14
Van Hul, W.15
-
65
-
-
18444400214
-
A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population
-
Staehling-Hampton K, Proll S, Paeper BW, et al. A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population. Am J Med Genet. 2002;110:144-152.
-
(2002)
Am J Med Genet
, vol.110
, pp. 144-152
-
-
Staehling-Hampton, K.1
Proll, S.2
Paeper, B.W.3
-
66
-
-
0036138735
-
Evidence for a role of p38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation
-
DOI 10.1016/S8756-3282(01)00660-3, PII S8756328201006603
-
Suzuki A, Guicheux J, Palmer G, et al. Evidence for a role of p38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation. Bone. 2002;30:91-98. (Pubitemid 34044306)
-
(2002)
Bone
, vol.30
, Issue.1
, pp. 91-98
-
-
Suzuki, A.1
Guicheux, J.2
Palmer, G.3
Miura, Y.4
Oiso, Y.5
Bonjour, J.-P.-P.6
Caverzasio, J.7
-
67
-
-
10744225313
-
Physical stress by magnetic force accelerates differentiation of human osteoblasts
-
DOI 10.1016/j.bbrc.2003.09.156
-
Yuge L, Okubo A, Miyashita T, et al. Physical stress by magnetic force accelerates differentiation of human osteoblasts. Biochem Biophys Res Commun. 2003;311:32-38. (Pubitemid 37297885)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.311
, Issue.1
, pp. 32-38
-
-
Yuge, L.1
Okubo, A.2
Miyashita, T.3
Kumagai, T.4
Nikawa, T.5
Takeda, S.6
Kanno, M.7
Urabe, Y.8
Sugiyama, M.9
Kataoka, K.10
-
68
-
-
0041623046
-
Cell differentiation and p38MAPK cascade are inhibited in human osteoblasts cultured in a three-dimensional clinostat
-
DOI 10.1290/1543-706X(2003)039<0089:CDAPCA>2.0.CO;2
-
Yuge L, Hide I, Kumagai T, et al. Cell differentiation and p38(MAPK) cascade are inhibited in human osteoblasts cultured in a three-dimensional clinostat. In Vitro Cell Dev Biol Anim. 2003;39:89-97. (Pubitemid 36944614)
-
(2003)
In Vitro Cellular and Developmental Biology - Animal
, vol.39
, Issue.1-2
, pp. 89-97
-
-
Yuge, L.1
Hide, I.2
Kumagai, T.3
Kumei, Y.4
Takeda, S.5
Kanno, M.6
Sugiyama, M.7
Kataoka, K.8
-
69
-
-
46249124836
-
Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: Roles of extracellular matrix, Shc, and mitogen-activated protein kinase
-
Lee DY, Yeh CR, Chang SF, et al. Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: roles of extracellular matrix, Shc, and mitogen-activated protein kinase. J Bone Miner Res. 2008;23:1140-1149.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 1140-1149
-
-
Lee, D.Y.1
Yeh, C.R.2
Chang, S.F.3
-
70
-
-
78649276976
-
Evaluation of short-term healing following sustained delivery of osteoinductive agents in a rat femur drill defect model
-
Technical Papers Composing the Proceedings of the 44th Annual Rocky Mountain Bioengineering Symposium and 44th Int. ISA Biomedical Sciences Instrumentation Symposium
-
Wingerter S, Tucci M, Bumgardner J, Benghuzzi H. Evaluation of short-term healing following sustained delivery of osteoinductive agents in a rat femur drill defect model. Biomed Sci Instrum. 2007;43:188-193. (Pubitemid 46668206)
-
(2007)
Biomedical Sciences Instrumentation
, vol.43
, pp. 188-193
-
-
Wingerter, S.1
Tucci, M.2
Bumgardner, J.3
Benghuzzi, H.4
-
71
-
-
34447343823
-
Bone morphogenetic proteins in clinical applications
-
DOI 10.1111/j.1445-2197.2007.04175.x
-
Gautschi OP, Frey SP, Zellweger R. Bone morphogenetic proteins in clinical applications. Aust NZ J Surg. 2007;77:626-631. (Pubitemid 47063348)
-
(2007)
ANZ Journal of Surgery
, vol.77
, Issue.8
, pp. 626-631
-
-
Gautschi, O.P.1
Frey, S.P.2
Zellweger, R.3
-
72
-
-
17044364765
-
Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo
-
DOI 10.1073/pnas.0500031102
-
Yoon BS, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM. Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci USA. 2005;102:5062-5067. (Pubitemid 40503739)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.14
, pp. 5062-5067
-
-
Yoon, B.S.1
Ovchinnikov, D.A.2
Yoshii, I.3
Mishina, Y.4
Behringer, R.R.5
Lyons, K.M.6
-
73
-
-
33845971522
-
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
-
Bandyopadhyay A, Tsuji K, Cox K, Harfe BD, Rosen V, Tabin CJ. Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet. 2006;2:e216.
-
(2006)
PLoS Genet
, vol.2
-
-
Bandyopadhyay, A.1
Tsuji, K.2
Cox, K.3
Harfe, B.D.4
Rosen, V.5
Tabin, C.J.6
-
74
-
-
33751506452
-
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
-
DOI 10.1038/ng1916, PII NG1916
-
Tsuji K, Bandyopadhyay A, Harfe BD, et al. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet. 2006;38:1424-1429. (Pubitemid 44837565)
-
(2006)
Nature Genetics
, vol.38
, Issue.12
, pp. 1424-1429
-
-
Tsuji, K.1
Bandyopadhyay, A.2
Harfe, B.D.3
Cox, K.4
Kakar, S.5
Gerstenfeld, L.6
Einhorn, T.7
Tabin, C.J.8
Rosen, V.9
-
75
-
-
13944283679
-
BMP receptor signaling is required for postnatal maintenance of articular cartilage
-
DOI 10.1371/journal.pbio.0020355
-
Rountree RB, Schoor M, Chen H, et al. BMP receptor signaling is required for postnatal maintenance of articular cartilage. PLoS Biol. 2004;2:e355. (Pubitemid 40280480)
-
(2004)
PLoS Biology
, vol.2
, Issue.11
-
-
Rountree, R.B.1
Schoor, M.2
Chen, H.3
Marks, M.E.4
Harley, V.5
Mishina, Y.6
Kingsley, D.M.7
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