메뉴 건너뛰기




Volumn 27, Issue 9, 2012, Pages 2001-2014

Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling

Author keywords

BONE MORPHOGENETIC PROTEINS; DIFFERENTIATION; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MESENCHYMAL STEM CELLS; PARATHYROID HORMONE

Indexed keywords

BETA ARRESTIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CHLORPROMAZINE; GREEN FLUORESCENT PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; NOGGIN; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE[1-34]; RAG2 PROTEIN; SMAD1 PROTEIN;

EID: 84865270952     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1663     Document Type: Article
Times cited : (135)

References (68)
  • 1
    • 33646435309 scopus 로고    scopus 로고
    • The stem cell niches in bone
    • Yin T, Li L,. The stem cell niches in bone. J Clin Invest. 2006; 116: 1195-201.
    • (2006) J Clin Invest. , vol.116 , pp. 1195-1201
    • Yin, T.1    Li, L.2
  • 5
    • 0031044104 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 stimulates differentiation in primary cultures of fetal rat calvarial osteoblasts
    • DOI 10.1023/A:1006853009828
    • Chaudhari A, Ron E, Rethman MP,. Recombinant human bone morphogenetic protein-2 stimulates differentiation in primary cultures of fetal rat calvarial osteoblasts. Mol Cell Biochem. 1997; 167: 31-9. (Pubitemid 27081330)
    • (1997) Molecular and Cellular Biochemistry , vol.167 , Issue.1-2 , pp. 31-39
    • Chaudhari, A.1    Ron, E.2    Rethman, M.P.3
  • 6
    • 0025129055 scopus 로고
    • Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs
    • Martin RB, Chow BD, Lucas PA,. Bone marrow fat content in relation to bone remodeling and serum chemistry in intact and ovariectomized dogs. Calcif Tissue Int. 1990; 46: 189-94. (Pubitemid 20084075)
    • (1990) Calcified Tissue International , vol.46 , Issue.3 , pp. 189-194
    • Martin, R.B.1    Chow, B.D.2    Lucas, P.A.3
  • 7
    • 0025854709 scopus 로고
    • Relationships between marrow fat and bone turnover in ovariectomized and intact rats
    • Martin RB, Zissimos SL,. Relationships between marrow fat and bone turnover in ovariectomized and intact rats. Bone. 1991; 12: 123-31.
    • (1991) Bone. , vol.12 , pp. 123-131
    • Martin, R.B.1    Zissimos, S.L.2
  • 8
    • 0028319607 scopus 로고
    • Temporal bone dynamics, the hard way. Formation, growth, modeling, repair and quantum type bone remodeling in the otic capsule
    • Sorensen MS,. Temporal bone dynamics, the hard way. Formation, growth, modeling, repair and quantum type bone remodeling in the otic capsule. Acta Otolaryngol Suppl. 1994; 512: 1-22.
    • (1994) Acta Otolaryngol Suppl. , vol.512 , pp. 1-22
    • Sorensen, M.S.1
  • 9
    • 0020064261 scopus 로고
    • Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: Differential effects of intermittent and continuous administration
    • Tam CS, Heersche JN, Murray TM, Parsons JA,. Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration. Endocrinology. 1982; 110: 506-12. (Pubitemid 12162946)
    • (1982) Endocrinology , vol.110 , Issue.2 , pp. 506-512
    • Tam, C.S.1    Heersche, J.N.M.2    Murray, T.M.3    Parsons, J.A.4
  • 10
    • 0026584625 scopus 로고
    • Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
    • Hock JM, Gera I,. Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone. J Bone Miner Res. 1992; 7: 65-72.
    • (1992) J Bone Miner Res. , vol.7 , pp. 65-72
    • Hock, J.M.1    Gera, I.2
  • 11
    • 1342329522 scopus 로고    scopus 로고
    • Parathyroid hormone: A double-edged sword for bone metabolism
    • DOI 10.1016/j.tem.2004.01.006
    • Qin L, Raggatt LJ, Partridge NC,. Parathyroid hormone: a double-edged sword for bone metabolism. Trends Endocrinol Metab. 2004; 15: 60-5. (Pubitemid 38253007)
    • (2004) Trends in Endocrinology and Metabolism , vol.15 , Issue.2 , pp. 60-65
    • Qin, L.1    Raggatt, L.J.2    Partridge, N.C.3
  • 13
    • 0023184613 scopus 로고
    • Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels
    • Yamaguchi DT, Hahn TJ, Iida-Klein A, Kleeman CR, Muallem S,. Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels. J Biol Chem. 1987; 262: 7711-8. (Pubitemid 17103903)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.16 , pp. 7711-7718
    • Yamaguchi, D.T.1    Hahn, T.J.2    Iida-Klein, A.3
  • 15
    • 0030831889 scopus 로고    scopus 로고
    • Parathyroid hormone enhances early and suppresses late stages of osteogenic and chondrogenic development in a BMP-dependent mesenchymal differentiation system (C3H10T 1/4 )
    • Hollnagel A, Ahrens M, Gross G,. Parathyroid hormone enhances early and suppresses late stages of osteogenic and chondrogenic development in a BMP-dependent mesenchymal differentiation system (C3H10T1/2). J Bone Miner Res. 1997; 12: 1993-2004. (Pubitemid 27524476)
    • (1997) Journal of Bone and Mineral Research , vol.12 , Issue.12 , pp. 1993-2004
    • Hollnagel, A.1    Ahrens, M.2    Gross, G.3
  • 16
    • 58149134327 scopus 로고    scopus 로고
    • The cell biology of parathyroid hormone in osteoblasts
    • Kousteni S, Bilezikian JP,. The cell biology of parathyroid hormone in osteoblasts. Curr Osteoporos Rep. 2008; 6: 72-6.
    • (2008) Curr Osteoporos Rep. , vol.6 , pp. 72-76
    • Kousteni, S.1    Bilezikian, J.P.2
  • 17
    • 34248577022 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
    • DOI 10.1016/j.bone.2007.03.017, PII S8756328207001731
    • Jilka RL,. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone. 2007; 40: 1434-46. (Pubitemid 46756429)
    • (2007) Bone , vol.40 , Issue.6 , pp. 1434-1446
    • Jilka, R.L.1
  • 18
    • 33644769212 scopus 로고    scopus 로고
    • Endocytosis conducts the cell signaling orchestra
    • Polo S, Di Fiore PP,. Endocytosis conducts the cell signaling orchestra. Cell. 2006; 124: 897-00.
    • (2006) Cell. , vol.124 , pp. 897-890
    • Polo, S.1    Di Fiore, P.P.2
  • 19
    • 77649249596 scopus 로고    scopus 로고
    • TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling
    • Qiu T, Wu X, Zhang F, Clemens TL, Wan M, Cao X,. TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling. Nat Cell Biol. 2010; 12: 224-34.
    • (2010) Nat Cell Biol. , vol.12 , pp. 224-234
    • Qiu, T.1    Wu, X.2    Zhang, F.3    Clemens, T.L.4    Wan, M.5    Cao, X.6
  • 20
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • DOI 10.1038/37284
    • Heldin CH, Miyazono K, ten Dijke P,. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature. 1997; 390: 465-71. (Pubitemid 28013118)
    • (1997) Nature , vol.390 , Issue.6659 , pp. 465-471
    • Heldin, C.-H.1    Miyazono, K.2    Ten Dijke, P.3
  • 21
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-beta superfamily
    • Attisano L, Wrana JL,. Signal transduction by the TGF-beta superfamily. Science. 2002; 296: 1646-7.
    • (2002) Science. , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 22
    • 24644507896 scopus 로고    scopus 로고
    • The disparate role of BMP in stem cell biology
    • DOI 10.1038/sj.onc.1208919, PII 1208919
    • Varga AC, Wrana JL,. The disparate role of BMP in stem cell biology. Oncogene. 2005; 24: 5713-21. (Pubitemid 43086131)
    • (2005) Oncogene , vol.24 , Issue.37 , pp. 5713-5721
    • Varga, A.C.1    Wrana, J.L.2
  • 23
    • 77952548279 scopus 로고    scopus 로고
    • Extracellular BMP-antagonist regulation in development and disease: Tied up in knots
    • Walsh DW, Godson C, Brazil DP, Martin F,. Extracellular BMP-antagonist regulation in development and disease: tied up in knots. Trends Cell Biol. 2010; 20: 244-56.
    • (2010) Trends Cell Biol. , vol.20 , pp. 244-256
    • Walsh, D.W.1    Godson, C.2    Brazil, D.P.3    Martin, F.4
  • 24
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonists, and the skeleton
    • DOI 10.1210/er.2002-0023
    • Canalis E, Economides AN, Gazzerro E,. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr Rev. 2003; 24: 218-35. (Pubitemid 36515285)
    • (2003) Endocrine Reviews , vol.24 , Issue.2 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 25
    • 8444237836 scopus 로고    scopus 로고
    • Dorsal-ventral patterning and neural induction in Xenopus embryos
    • DOI 10.1146/annurev.cellbio.20.011403.154124
    • De Robertis EM, Kuroda H,. Dorsal-ventral patterning and neural induction in Xenopus embryos. Annu Rev Cell Dev Biol. 2004; 20: 285-308. (Pubitemid 39488640)
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 285-308
    • De Robertis, E.M.1    Kuroda, H.2
  • 26
    • 32244437156 scopus 로고    scopus 로고
    • Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing
    • DOI 10.1242/dev.02214
    • O'Connor MB, Umulis D, Othmer HG, Blair SS,. Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing. Development. 2006; 133: 183-93. (Pubitemid 43210708)
    • (2006) Development , vol.133 , Issue.2 , pp. 183-193
    • O'Connor, M.B.1    Umulis, D.2    Othmer, H.G.3    Blair, S.S.4
  • 27
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way
    • DOI 10.1242/dev.01117
    • He X, Semenov M, Tamai K, Zeng X,. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development. 2004; 131: 1663-77. (Pubitemid 38559836)
    • (2004) Development , vol.131 , Issue.8 , pp. 1663-1677
    • He, X.1    Semenov, M.2    Tamai, K.3    Zeng, X.4
  • 28
    • 73949136201 scopus 로고    scopus 로고
    • Crosstalk between Wnt and bone morphogenic protein signaling: A turbulent relationship
    • Itasaki N, Hoppler S,. Crosstalk between Wnt and bone morphogenic protein signaling: a turbulent relationship. Dev Dyn. 2010; 239: 16-33.
    • (2010) Dev Dyn. , vol.239 , pp. 16-33
    • Itasaki, N.1    Hoppler, S.2
  • 29
    • 0042131956 scopus 로고    scopus 로고
    • A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
    • DOI 10.1128/MCB.23.16.5825-5835.2003
    • Liu G, Bafico A, Harris VK, Aaronson SA,. A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Mol Cell Biol. 2003; 23: 5825-35. (Pubitemid 36951344)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.16 , pp. 5825-5835
    • Liu, G.1    Bafico, A.2    Harris, V.K.3    Aaronson, S.A.4
  • 30
    • 22844445934 scopus 로고    scopus 로고
    • SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
    • DOI 10.1074/jbc.M504308200
    • Semenov M, Tamai K, He X,. SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem. 2005; 280: 26770-5. (Pubitemid 41040710)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.29 , pp. 26770-26775
    • Semenov, M.1    Tamai, K.2    He, X.3
  • 34
  • 35
    • 0026351807 scopus 로고
    • Identification and characterization of cellular binding proteins (receptors) for recombinant human bone morphogenetic protein 2B, an initiator of bone differentiation cascade
    • Paralkar VM, Hammonds RG, Reddi AH,. Identification and characterization of cellular binding proteins (receptors) for recombinant human bone morphogenetic protein 2B, an initiator of bone differentiation cascade. Proc Natl Acad Sci U S A. 1991; 88: 3397-401. (Pubitemid 21916628)
    • (1991) Proceedings of the National Academy of Sciences of the United States of America , vol.88 , Issue.8 , pp. 3397-3401
    • Paralkar, V.M.1    Hammonds, R.G.2    Reddi, A.H.3
  • 36
    • 78049510298 scopus 로고    scopus 로고
    • Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling
    • Wu X, Pang L, Lei W, Lu W, Li J, Li Z, Frassica FJ, Chen X, Wan M, Cao X,. Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling. Cell Stem Cell. 2010; 7: 571-80.
    • (2010) Cell Stem Cell. , vol.7 , pp. 571-580
    • Wu, X.1    Pang, L.2    Lei, W.3    Lu, W.4    Li, J.5    Li, Z.6    Frassica, F.J.7    Chen, X.8    Wan, M.9    Cao, X.10
  • 38
    • 54349084787 scopus 로고    scopus 로고
    • Differentiation and proliferation of periosteal osteoblast progenitors are differentially regulated by estrogens and intermittent parathyroid hormone administration
    • Ogita M, Rached MT, Dworakowski E, Bilezikian JP, Kousteni S,. Differentiation and proliferation of periosteal osteoblast progenitors are differentially regulated by estrogens and intermittent parathyroid hormone administration. Endocrinology. 2008; 149: 5713-23.
    • (2008) Endocrinology. , vol.149 , pp. 5713-5723
    • Ogita, M.1    Rached, M.T.2    Dworakowski, E.3    Bilezikian, J.P.4    Kousteni, S.5
  • 39
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
    • DOI 10.1038/35077108
    • Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C,. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 2001; 411: 321-5. (Pubitemid 32467039)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3    Hoppe, D.4    Stannek, P.5    Glinka, A.6    Niehrs, C.7
  • 41
    • 37549002128 scopus 로고    scopus 로고
    • NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling
    • Wang B, Bisello A, Yang Y, Romero GG, Friedman PA,. NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling. J Biol Chem. 2007; 282: 36214-22.
    • (2007) J Biol Chem. , vol.282 , pp. 36214-36222
    • Wang, B.1    Bisello, A.2    Yang, Y.3    Romero, G.G.4    Friedman, P.A.5
  • 42
    • 34547103996 scopus 로고    scopus 로고
    • β-Arrestin-dependent parathyroid hormone-stimulated extracellular signal-regulated kinase activation and parathyroid hormone type 1 receptor internalization
    • DOI 10.1210/en.2007-0343
    • Sneddon WB, Friedman PA,. Beta-arrestin-dependent parathyroid hormone-stimulated extracellular signal-regulated kinase activation and parathyroid hormone type 1 receptor internalization. Endocrinology. 2007; 148: 4073-9. (Pubitemid 47105863)
    • (2007) Endocrinology , vol.148 , Issue.8 , pp. 4073-4079
    • Sneddon, W.B.1    Friedman, P.A.2
  • 45
    • 41549139755 scopus 로고    scopus 로고
    • Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays
    • DOI 10.1016/j.stem.2008.03.002, PII S1934590908001148
    • Bianco P, Robey PG, Simmons PJ,. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell. 2008; 2: 313-9. (Pubitemid 351467394)
    • (2008) Cell Stem Cell , vol.2 , Issue.4 , pp. 313-319
    • Bianco, P.1    Robey, P.G.2    Simmons, P.J.3
  • 46
    • 75749146169 scopus 로고    scopus 로고
    • Coexistence of quiescent and active adult stem cells in mammals
    • Li L, Clevers H,. Coexistence of quiescent and active adult stem cells in mammals. Science. 2010; 327: 542-5.
    • (2010) Science. , vol.327 , pp. 542-545
    • Li, L.1    Clevers, H.2
  • 47
    • 0030698388 scopus 로고    scopus 로고
    • Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2
    • Lecanda F, Avioli LV, Cheng SL,. Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem. 1997; 67: 386-96.
    • (1997) J Cell Biochem. , vol.67 , pp. 386-396
    • Lecanda, F.1    Avioli, L.V.2    Cheng, S.L.3
  • 48
    • 0031012411 scopus 로고    scopus 로고
    • Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro
    • DOI 10.1002/(SICI)1097-4644(199702)64:2<295::AID-JCB12>3.0.CO;2-I
    • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP,. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem. 1997; 64: 295-312. (Pubitemid 27065443)
    • (1997) Journal of Cellular Biochemistry , vol.64 , Issue.2 , pp. 295-312
    • Jaiswal, N.1    Haynesworth, S.E.2    Caplan, A.I.3    Bruder, S.P.4
  • 51
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-beta signals
    • Moustakas A, Heldin CH,. Non-Smad TGF-beta signals. J Cell Sci. 2005; 118: 3573-84.
    • (2005) J Cell Sci. , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 52
    • 58149216052 scopus 로고    scopus 로고
    • Signaling cross-talk between TGF-beta/BMP and other pathways
    • Guo X, Wang XF,. Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res. 2009; 19: 71-88.
    • (2009) Cell Res. , vol.19 , pp. 71-88
    • Guo, X.1    Wang, X.F.2
  • 53
    • 33846000938 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion
    • DOI 10.1634/stemcells.2005-0544
    • Zhang J, He XC, Tong WG, Johnson T, Wiedemann LM, Mishina Y, Feng JQ, Li L,. Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells. 2006; 24: 2826-39. (Pubitemid 46053019)
    • (2006) Stem Cells , vol.24 , Issue.12 , pp. 2826-2839
    • Zhang, J.1    He, X.C.2    Tong, W.-G.3    Johnson, T.4    Wiedemann, L.M.5    Mishina, Y.6    Feng, J.Q.7    Li, L.8
  • 54
    • 33846282292 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling regulates expression of PRDC, an antagonist of the BMP-4 signaling pathway
    • DOI 10.1016/j.bbrc.2006.12.205, PII S0006291X07000058
    • Im J, Kim H, Kim S, Jho EH,. Wnt/beta-catenin signaling regulates expression of PRDC, an antagonist of the BMP-4 signaling pathway. Biochem Biophys Res Commun. 2007; 354: 296-301. (Pubitemid 46123233)
    • (2007) Biochemical and Biophysical Research Communications , vol.354 , Issue.1 , pp. 296-301
    • Im, J.1    Kim, H.2    Kim, S.3    Jho, E.-h.4
  • 56
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz RJ, Shenoy SK,. Transduction of receptor signals by beta-arrestins. Science. 2005; 308: 512-7.
    • (2005) Science. , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 58
    • 69249112245 scopus 로고    scopus 로고
    • Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals
    • Lintern KB, Guidato S, Rowe A, Saldanha JW, Itasaki N,. Characterization of wise protein and its molecular mechanism to interact with both Wnt and BMP signals. J Biol Chem. 2009; 284: 23159-68.
    • (2009) J Biol Chem. , vol.284 , pp. 23159-23168
    • Lintern, K.B.1    Guidato, S.2    Rowe, A.3    Saldanha, J.W.4    Itasaki, N.5
  • 60
    • 81255176589 scopus 로고    scopus 로고
    • Antagonists of LRP6 regulate PTH-induced cAMP generation
    • Shi C, Li J, Wang W, Cao W, Cao X, Wan M,. Antagonists of LRP6 regulate PTH-induced cAMP generation. Ann N Y Acad Sci. 2011; 1237: 39-46.
    • (2011) Ann N y Acad Sci. , vol.1237 , pp. 39-46
    • Shi, C.1    Li, J.2    Wang, W.3    Cao, W.4    Cao, X.5    Wan, M.6
  • 61
    • 0345167829 scopus 로고    scopus 로고
    • Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression
    • DOI 10.1016/S1044-7431(03)00232-X
    • Haegele L, Ingold B, Naumann H, Tabatabai G, Ledermann B, Brandner S,. Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression. Mol Cell Neurosci. 2003; 24: 696-708. (Pubitemid 37506013)
    • (2003) Molecular and Cellular Neuroscience , vol.24 , Issue.3 , pp. 696-708
    • Haegele, L.1    Ingold, B.2    Naumann, H.3    Tabatabai, G.4    Ledermann, B.5    Brandner, S.6
  • 62
    • 0038485600 scopus 로고    scopus 로고
    • Lymphoid enhancer factor-1 and β-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter
    • DOI 10.1074/jbc.M211443200
    • Kahler RA, Westendorf JJ,. Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter. J Biol Chem. 2003; 278: 11937-44. (Pubitemid 36800167)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 11937-11944
    • Kahler, R.A.1    Westendorf, J.J.2
  • 63
    • 0030598829 scopus 로고    scopus 로고
    • The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
    • DOI 10.1016/S0092-8674(00)80133-6
    • Zimmerman LB, De Jesus-Escobar JM, Harland RM,. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell. 1996; 86: 599-606. (Pubitemid 26299491)
    • (1996) Cell , vol.86 , Issue.4 , pp. 599-606
    • Zimmerman, L.B.1    De Jesus-Escobar, J.M.2    Harland, R.M.3
  • 65
    • 2942532689 scopus 로고    scopus 로고
    • 3
    • DOI 10.1089/154732804323099208
    • Sammons J, Ahmed N, El-Sheemy M, Hassan HT,. The role of BMP-6, IL-6, and BMP-4 in mesenchymal stem cell-dependent bone development: effects on osteoblastic differentiation induced by parathyroid hormone and vitamin D(3). Stem Cells Dev. 2004; 13: 273-80. (Pubitemid 38738369)
    • (2004) Stem Cells and Development , vol.13 , Issue.3 , pp. 273-280
    • Sammons, J.1    Ahmed, N.2    El-Sheemy, M.3    Hassan, H.T.4
  • 66
    • 77956255227 scopus 로고    scopus 로고
    • The effect of bone morphogenetic protein-2, bone morphogenetic protein-7, parathyroid hormone, and platelet-derived growth factor on the proliferation and osteogenic differentiation of mesenchymal stem cells derived from osteoporotic bone
    • Pountos I, Georgouli T, Henshaw K, Bird H, Jones E, Giannoudis PV,. The effect of bone morphogenetic protein-2, bone morphogenetic protein-7, parathyroid hormone, and platelet-derived growth factor on the proliferation and osteogenic differentiation of mesenchymal stem cells derived from osteoporotic bone. J Orthop Trauma. 2010; 24: 552-6.
    • (2010) J Orthop Trauma. , vol.24 , pp. 552-556
    • Pountos, I.1    Georgouli, T.2    Henshaw, K.3    Bird, H.4    Jones, E.5    Giannoudis, P.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.