The effect of neuropeptide y on brown-like adipocyte's differentiation and activation

Peptides

Volumn 63, Issue , 2015, Pages 126-133

  Wan, Yun ^a   Xue, Ruidan ^a   Wang, Yi ^a   Zhang, Qiongyue ^a   Huang, Shan ^a   Wu, Wei ^a   Ye, Hongying ^a   Zhang, Zhaoyun ^a   Li, Yiming ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Brown adipogenesis; Brown fat like adipocytes; C3H10T1 2; Neuropeptide Y

Indexed keywords

5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; ANTIMYCIN A1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C1; MESSENGER RNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NEUROPEPTIDE Y; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; APOPTOSIS REGULATORY PROTEIN; CIDEA PROTEIN, MOUSE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; IODIDE PEROXIDASE; IODOTHYRONINE DEIODINASE TYPE II; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADIPOGENESIS; ANIMAL CELL; ARTICLE; BROWN ADIPOSE TISSUE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; LIPID STORAGE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; BROWN ADIPOCYTE; CELL LINE; DRUG EFFECTS; GENE SILENCING; GENETICS; METABOLISM; PHYSIOLOGY; SECOND MESSENGER;

ADIPOCYTES, BROWN; ANIMALS; APOPTOSIS REGULATORY PROTEINS; CELL DIFFERENTIATION; CELL LINE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION; GENE SILENCING; IODIDE PEROXIDASE; ION CHANNELS; MICE; MITOCHONDRIAL PROTEINS; NEUROPEPTIDE Y; SECOND MESSENGER SYSTEMS; TRANSCRIPTION FACTORS;

EID: 84915746471     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.10.018     Document Type: Article

References (36)

1. G. Barbatelli, I. Murano, L. Madsen, Q. Hao, M. Jimenez, and K. Kristiansen The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation Am J Physiol Endocrinol Metab 298 2010 E1244 E1253
2. S.P. Brothers, and C. Wahlestedt Therapeutic potential of neuropeptide Y (NPY) receptor ligands EMBO Mol Med 2 2010 429 439
3. W. Cao, K.W. Daniel, J. Robidoux, P. Puigserver, A.V. Medvedev, and X. Bai p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene Mol Cell Biol 24 2004 3057 3067
4. P.T. Chao, L. Yang, S. Aja, T.H. Moran, and S. Bi Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity Cell Metab 13 2011 573 583
5. A.M. Cypess, S. Lehman, G. Williams, I. Tal, D. Rodman, and A.B. Goldfine Identification and importance of brown adipose tissue in adult humans N Engl J Med 360 2009 1509 1517
6. L.A. de Jesus, S.D. Carvalho, M.O. Ribeiro, M. Schneider, S.W. Kim, and J.W. Harney The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue J Clin Invest 108 2001 1379 1385
7. W.P. De Potter, P. Partoens, A. Schoups, I. Llona, and E.P. Coen Noradrenergic neurons release both noradrenaline and neuropeptide Y from a single pool: the large dense cored vesicles Synapse 25 1997 44 55
8. M. Egawa, H. Yoshimatsu, and G.A. Bray Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats Am J Physiol 260 1991 R328 R334
9. K.L. Ellacott, and R.D. Cone The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis Recent Prog Horm Res 59 2004 395 408
10. H. Herzog, K. Darby, H. Ball, Y. Hort, A. Beck-Sickinger, and J. Shine Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation Genomics 41 1997 315 319
11. M.M. Kamiji, and A. Inui Neuropeptide y receptor selective ligands in the treatment of obesity Endocr Rev 28 2007 664 684
12. M. Kanevskij, G. Taimor, M. Schafer, H.M. Piper, and K.D. Schluter Neuropeptide Y modifies the hypertrophic response of adult ventricular cardiomyocytes to norepinephrine Cardiovasc Res 53 2002 879 887
13. K. Kos, A.R. Baker, M. Jernas, A.L. Harte, J.C. Clapham, and J.P. O'Hare DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissue Diabetes Obes Metab 11 2009 285 292
14. L.E. Kuo, J.B. Kitlinska, J.U. Tilan, L. Li, S.B. Baker, and M.D. Johnson Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome Nat Med 13 2007 803 811
15. S. Lin, D. Boey, and H. Herzog NPY and Y receptors: lessons from transgenic and knockout models Neuropeptides 38 2004 189 200
16. J.M. Lundberg, A. Rudehill, and A. Sollevi Pharmacological characterization of neuropeptide Y and noradrenaline mechanisms in sympathetic control of pig spleen Eur J Pharmacol 163 1989 103 113
17. G.C. Major, E. Doucet, P. Trayhurn, A. Astrup, and A. Tremblay Clinical significance of adaptive thermogenesis Int J Obes (Lond) 31 2007 204 212
18. J. Nedergaard, T. Bengtsson, and B. Cannon Three years with adult human brown adipose tissue Ann N Y Acad Sci 1212 2010 E20 E36
19. J. Nedergaard, V. Golozoubova, A. Matthias, A. Asadi, A. Jacobsson, and B. Cannon UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency Biochim Biophys Acta 1504 2001 82 106
20. H. Oberkofler, G. Dallinger, Y.M. Liu, E. Hell, F. Krempler, and W. Patsch Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans J Lipid Res 38 1997 2125 2133
21. P. Puigserver, Z. Wu, C.W. Park, R. Graves, M. Wright, and B.M. Spiegelman A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis Cell 92 1998 829 839
22. V. Puri, S. Ranjit, S. Konda, S.M. Nicoloro, J. Straubhaar, and A. Chawla Cidea is associated with lipid droplets and insulin sensitivity in humans Proc Natl Acad Sci U S A 105 2008 7833 7838
23. P. Seale, H.M. Conroe, J. Estall, S. Kajimura, A. Frontini, and J. Ishibashi Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice J Clin Invest 121 2011 96 105
24. Y.C. Shi, J. Lau, Z. Lin, H. Zhang, L. Zhai, and G. Sperk Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN Cell Metab 17 2013 236 248
25. Y.C. Shi, S. Lin, L. Castillo, A. Aljanova, R.F. Enriquez, and A.D. Nguyen Peripheral-specific y2 receptor knockdown protects mice from high-fat diet-induced obesity Obesity (Silver Spring) 19 2011 2137 2148
26. C. Sitticharoon, S. Chatree, and M. Churintaraphan Expressions of neuropeptide Y and Y1 receptor in subcutaneous and visceral fat tissues in normal weight and obese humans and their correlations with clinical parameters and peripheral metabolic factors Regul Pept 185 2013 65 72
27. B.M. Spiegelman Transcriptional control of energy homeostasis through the PGC1 coactivators Novartis Found Symp 286 2007 3-6, 6-12, 162-163, 196-203
28. K. Tatemoto, M. Carlquist, and V. Mutt Neuropeptide Y - a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide Nature 296 1982 659 660
29. S.M. Taylor, and P.A. Jones Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine Cell 17 1979 771 779
30. L.W. van Marken, J.W. Vanhommerig, N.M. Smulders, J.M. Drossaerts, G.J. Kemerink, and N.D. Bouvy Cold-activated brown adipose tissue in healthy men N Engl J Med 360 2009 1500 1508
31. K.A. Virtanen, M.E. Lidell, J. Orava, M. Heglind, R. Westergren, and T. Niemi Functional brown adipose tissue in healthy adults N Engl J Med 360 2009 1518 1525
32. J. Wu, P. Bostrom, L.M. Sparks, L. Ye, J.H. Choi, and A.H. Giang Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human Cell 150 2012 366 376
33. J. Wu, P. Cohen, and B.M. Spiegelman Adaptive thermogenesis in adipocytes: is beige the new brown Genes Dev 27 2013 234 250
34. R. Xue, Y. Wan, S. Zhang, Q. Zhang, H. Ye, and Y. Li Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes Am J Physiol Endocrinol Metab 306 2014 E363 E372
35. K. Yang, H. Guan, E. Arany, D.J. Hill, and X. Cao Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor FASEB J 22 2008 2452 2464
36. F. Zheng, Y.J. Kim, P.T. Chao, and S. Bi Overexpression of neuropeptide Y in the dorsomedial hypothalamus causes hyperphagia and obesity in rats Obesity (Silver Spring) 21 2013 1086 1092