JNK signaling plays an important role in the effects of TNF-α and IL-1β on in vitro osteoblastic differentiation of cultured human periosteal-derived cells

Molecular Biology Reports

Volumn 40, Issue 8, 2013, Pages 4869-4881

  Hah, Young Sool ^a   Kang, Hea Gea ^b   Cho, Hee Young ^a   Shin, Sang Hoon ^b   Kim, Uk Kyu ^b   Park, Bong Wook ^c   Lee, Sang Il ^c   Rho, Gyu Jin ^a   Kim, Jong Ryoul ^d   Byun, June Ho ^c  

^a Gyeongsang National University   (South Korea)

^b Pusan National University   (South Korea)

^c Gyeongsang National University School of Medicine   (South Korea)

^d Maxillofacial Center Onhospital   (South Korea)

Author keywords

IL 1 ; JNK signaling; Periosteal derived cells; TNF

Indexed keywords

ALIZARIN RED S; ALKALINE PHOSPHATASE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OSTEOCALCIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; ARTICLE; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; OSTEOBLAST; PERIOSTEAL DERIVED CELL; PERIOSTEUM; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

EID: 84881153583     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-013-2586-3     Document Type: Article

References (33)

1. Lerner UH (2006) Inflammation-induced bone remodeling in periodontal disease and the influence of post-menopausal osteoporosis. J Dent Res 85:596-607
2. Walsh NC, Gravallese EM (2010) Bone remodeling in rheumatic disease: a question of balance. Immunol Rev 233:301-312
3. Schwarz EM, Lu AP, Goater JJ, Benz EB, Kollias G, Rosier RN, Puzas JE, O'Keefe RJ (2000) Tumor necrosis factor-alpha/nuclear transcription factor-κB signaling in periprosthetic osteolysis. J Orthop Res 18:472-480
4. Hughes FJ, Turner W, Belibasakis G, Martuscelli G (2006) Effects of growth factors and cytokines on osteoblast differentiation. Periodontology 41:48-72
5. Bakker AD, Silva VC, Krishnan R, Bacabac RG, Blaauboer ME, Lin YC, Marcantonio RA, Cirelli JA, Klein-Nulend J (2009) Tumor necrosis factor alpha and interleukin-1β modulate calcium and nitric oxide signaling in mechanically stimulated osteocytes. Arthr Rheum 60:3336-3345
6. Marie PJ, Fromigué O (2006) Osteogenic differentiation of human marrow-derived mesenchymal stem cells. Regen Med 1:539-548
7. Song IH, Caplan AI, Dennis JE (2009) In vitro dexamethasone pretreatment enhances bone formation of human mesenchymal stem cells in vivo. J Orthop Res 27:916-921
8. Graziano A, d'Aquino R, Laino G, et al. (2008) Dental pulp stem cells: a promising tool for bone regeneration. Stem Cell Rev 4:21-26
9. Guillot PV, De Bari C, Dell'Accio F, et al. (2008) Comparative osteogenic transcription profiling of various fetal and adult mesenchymal stem cell sources. Differentiation 76:946-957
10. Cheng H, Qiu L, Ma J, Zhang H, Cheng M, Li W, Zhao X, Liu K (2011) Replicative senescence of human bone marrow and umbilical cord derived mesenchymal stem cells and their differentiation to adipocytes and osteoblasts. Mol Biol Rep 38:5161-5168
11. Park BW, Hah YS, Kim DR, Kim JR, Byun JH (2007) Osteogenic phenotypes and mineralization of cultured human periosteal-derived cells. Arch Oral Biol 52:983-989
12. Park BW, Hah YS, Kim DR, Kim JR, Byun JH (2008) Vascular endothelial growth factor expression in cultured periosteal-derived cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:554-560
13. Ryu YM, Hah YS, Park BW, Kim DR, Roh GS, Kim JR, Kim UK, Rho GJ, Maeng GH, Byun JH (2011) Osteogenic differentiation of human periosteal-derived cells in a three-dimensional collagen scaffold. Mol Biol Rep 38:2887-2894
14. Lacey DC, Simmons PJ, Graves SE, Hamilton JA (2009) Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation. Osteoarthr Cartil 17:735-742
15. Jeffcoate WJ, Game F, Cavanagh PR (2005) The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes. Lancet 366:2058-2061
16. Ichikawa H, Nair MS, Takada Y, Sheeja DB, Kumar MA, Oommen OV, Aggarwal BB (2006) Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-κB (nf-κB) activation and nf-κB-regulated gene expression. Clin Cancer Res 12:5910-5918
17. Krum SA, Chang J, Miranda-Carboni G, Wang CY (2010) Novel functions for NFκB: inhibition of bone formation. Nat Rev Rheumatol 6:607-611
18. Ziros PG, Gil AP, Georgakopoulos T, Habeos I, Kletsas D, Basdra EK, Papavassiliou AG (2002) The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells. J Biol Chem 277:23934-23941
19. Thirunavukkarasu K, Pei Y, Moore TL, Wei T, Wang H, Chandrasekhar S (2007) Regulation of NFATc2 gene expression by the transcription factor Runx2. Mol Biol Rep 34:1-10
20. Pantouli E, Boehm MM, Koka S (2005) Inflammatory cytokines activate p38 MAPK to induce osteoprotegerin synthesis by MG-63 cells. Biochem Biophys Res Commun 329:224-229
21. Yamashita M, Otsuka F, Mukai T, Otani H, Inagaki K, Miyoshi T, Goto J, Yamamura M, Makino H (2008) Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway. J Endocrinol 196:601-613
22. Hah YS, Jun JS, Lee SG, Park BW, Kim DR, Kim UK, Kim JR, Byun JH (2011) Vascular endothelial growth factor stimulates osteoblastic differentiation of cultured human periosteal-derived cells expressing vascular endothelial growth factor receptors. Mol Biol Rep 38:1443-1450
23. Huang W, Yang S, Shao J, Li YP (2007) Signaling and transcriptional regulation in osteoblast commitment and differentiation. Front Biosci 12:3068-3092
24. Iotsova V, Caamaño J, Loy J, Yang Y, Lewin A, Bravo R (1997) Osteopetrosis in mice lacking NF-κB1 and NF-κB2. Nat Med 3:1285-1289
25. Stein GS, Lian JB, van Wijnen AJ, Stein JL, Montecino M, Javed A, Zaidi SK, Young DW, Choi JY, Pockwinse SM (2004) Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene 23(24):4315-4329
26. Xiao G, Jiang D, Thomas P, Benson MD, Guan K, Karsenty G, Franceschi RT (2000) MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. J Biol Chem 275:4453-4459
27. Kanno T, Takahashi T, Tsujisawa T, Ariyoshi W, Nishihara T (2007) Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts. J Cell Biochem 101:1266-1277
28. Cuadrado A, Nebreda AR (2010) Mechanisms and functions of p38 MAPK signalling. Biochem J 429:403-417
29. Li Q, Yu H, Zinna R, Martin K, Herbert B, Liu A, Rossa C Jr, Kirkwood KL (2011) Silencing mitogen-activated protein kinase-activated protein kinase-2 arrests inflammatory bone loss. J Pharmacol Exp Ther 336:633-642
30. Zhao X, He W, Song Z, Tong Z, Li S, Ni L (2012) Mineral trioxide aggregate promotes odontoblastic differentiation via mitogen-activated protein kinase pathway in human dental pulp stem cells. Mol Biol Rep 39:215-220
31. Takeuchi Y, Suzawa M, Kikuchi T, Nishida E, Fujita T, Matsumoto T (1997) Differentiation and transforming growth factor-beta receptor down-regulation by collagen-alpha2beta1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells. J Biol Chem 272:29309-29316
32. Suzuki A, Palmer G, Bonjour JP, Caverzasio J (1999) Regulation of alkaline phosphatase activity by p38 MAP kinase in response to activation of Gi protein-coupled receptors by epinephrine in osteoblast-like cells. Endocrinology 140:3177-3182
33. Kakita A, Suzuki A, Ono Y, Miura Y, Itoh M, Oiso Y (2004) Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells. Prostaglandins Leukot Essent Fatty Acids 70:469-474