Adiponectin Impairs Chicken Preadipocytes Differentiation through p38 MAPK/ATF-2 and TOR/p70 S6 Kinase Pathways

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Yan, Jun ^a   Gan, Lu ^a   Chen, Di ^a   Sun, Chao ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 2; ADIPONECTIN; BETA ACTIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; FAT DROPLET; FATTY ACID SYNTHASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RAPAMYCIN; S6 KINASE; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; TRIACYLGLYCEROL LIPASE; AZO COMPOUND; GENETIC MARKER; OIL RED O;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHICKEN; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE OVEREXPRESSION; INHIBITION KINETICS; LIPID METABOLISM; LIPOLYSIS; MALE; MARKER GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROADIPOCYTE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALYSIS OF VARIANCE; ANIMAL; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECTS; GENE VECTOR; GENETIC MARKER; GENETICS; METABOLISM; MOLECULAR CLONING; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ADIPOCYTES; ADIPONECTIN; ANALYSIS OF VARIANCE; ANIMALS; AZO COMPOUNDS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CHICKENS; CLONING, MOLECULAR; ENZYME ACTIVATION; GENETIC MARKERS; GENETIC VECTORS; MALE; MAP KINASE SIGNALING SYSTEM; REAL-TIME POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84886002180     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077716     Document Type: Article

References (36)

1. Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF, (1995) A novel serum-protein similar to C1Q, produced exclusively in adipocytes. J Biol Chem 270: 26746-26749.
2. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, et al. (1996) CDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose most abundant gene transcript 1). Biochem Biophys Res Commun 221: 286-289.
3. Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, et al. (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8: 1288-1295.
4. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, et al. (1999) Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity. Biochem Biophys Res Commun 257: 79-83.
5. Lindsay RS, Funahashi T, Hanson RL, Matsuzawa Y, Tanaka S, et al. (2002) Adiponectin and development of type 2 diabetes in the Pima Indian population. The Lancet 360: 57-58.
6. Lindsay RS, Funahashi T, Krakoff J, Matsuzawa Y, Tanaka S, et al. (2003) Genome-wide linkage analysis of serum adiponectin in the Pima Indian population. Diabetes 52: 2419-2425.
7. Hendricks GL III, Hadley JA, Krzysik-Walker SM, Prabhu KS, Vasilatos-Younken R, et al. (2009) Unique Profile of Chicken Adiponectin, a Predominantly Heavy Molecular Weight Multimer, and Relationship to Visceral Adiposity. Endocrinology 150: 3092-3100.
8. Fu YC, Luo NL, Klein RL, Garvey WT, (2005) Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res 46: 1369-1379.
9. Bauche IB, El Mkadem SA, Pottier A-M, Senou M, Many M-C, et al. (2007) Overexpression of adiponectin targeted to adipose tissue in transgenic mice: Impaired adipocyte differentiation. Endocrinology 148: 1539-1549.
10. Ono K, Han J, (2000) The p38 signal transduction pathway Activation and function. Cell Signal 12: 1-13.
11. Xin X, Zhou L, Reyes CM, Liu F, Dong LQ, (2011) APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway. Am J Physiol Endocrinol Metab 300: E103-E110.
12. Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, et al. (2003) Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423: 762-769.
13. Aouadi M, Laurent K, Prot M, Le Marchand-Brustel Y, Binetruy B, et al. (2006) Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages. Diabetes 55: 281-289.
14. Vlahopoulos SA, Logotheti S, Micas D, Giarika A, Gorgoulis V, et al. (2008) The role of ATF-2 in oncogenesis. Bioessays 30: 314-327.
15. Maekawa T, Sano Y, Shinagawa T, Rahman Z, Sakuma T, et al. (2007) ATF-2 controls transcription of Maspin and GADD45[alpha] genes independently from p53 to suppress mammary tumors. Oncogene 27: 1045-1054.
16. Cho HJ, Park J, Lee HW, Lee YS, Kim JB, (2004) Regulation of adipocyte differentiation and insulin action with rapamycin. Biochem Biophys Res Commun 321: 942-948.
17. Sun C, Wei Z-w, Li Y, (2011) DHA regulates lipogenesis and lipolysis genes in mice adipose and liver. Mol Biol Rep 38: 731-737.
18. Liu Q, Yuan B, Lo KA, Patterson HC, Sun Y, et al. (2012) Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism. Proc Natl Acad Sci U S A 109: 14568-14573.
19. Coppola A, Marfella R, Coppola L, Tagliamonte E, Fontana D, et al. (2009) Effect of weight loss on coronary circulation and adiponectin levels in obese women. Int J Cardiol 134: 414-416.
20. Ouchi N, Kihara S, Funahashi T, Matsuzawa Y, Walsh K, (2003) Obesity, adiponectin and vascular inflammatory disease. Curr Opin Lipidol 14: 561-566.
21. Tahmoorespur M, Ghazanfari S, Nobari K, (2010) Evaluation of adiponectin gene expression in the abdominal adipose tissue of broiler chickens: Feed restriction, dietary energy, and protein influences adiponectin messenger ribonucleic acid expression. Poult Sci 89: 2092-2100.
22. Masaki T, Chiba S, Yasuda T, Tsubone T, Kakuma T, et al. (2003) Peripheral, but not central, administration of adiponectin reduces visceral adiposity and upregulates the expression of uncoupling protein in agouti yellow (Ay/a) obese mice. Diabetes 52: 2266-2273.
23. Mao X, Kikani CK, Riojas RA, Langlais P, Wang L, et al. (2006) APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat Cell Biol 8: 516-523.
24. Faubert B, Boily G, Izreig S, Griss T, Samborska B, et al. (2013) AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo. Cell Metab 17: 113-124.
25. Chabrolle C, Tosca L, Crochet S, Tesseraud S, Dupont J, (2007) Expression of adiponectin and its receptors (AdipoR1 and AdipoR2) in chicken ovary: potential role in ovarian steroidogenesis. Domest Anim Endocrinol 33: 480-487.
26. Cheng SW, Fryer LG, Carling D, Shepherd PR, (2004) Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status. J Biol Chem 279: 15719-15722.
27. Luo XH, Guo LJ, Yuan LQ, Xie H, Zhou HD, et al. (2005) Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway. Exp Cell Res 309: 99-109.
28. Yeh WC, Bierer BE, McKnight SL, (1995) Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proc Natl Acad Sci U S A 92: 11086-11090.
29. Engelman JA, Lisanti MP, Scherer PE, (1998) Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J Biol Chem 273: 32111-32120.
30. Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, et al. (1995) Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270: 7420-7426.
31. Shuman JD, Cheong J, Coligan JE, (1997) ATF-2 and C/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation. J Biol Chem 272: 12793-12800.
32. Wanninger J, Neumeier M, Weigert J, Bauer S, Weiss TS, et al. (2009) Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-kappaB, and STAT3 signaling pathways. Am J Physiol Gastrointest Liver Physiol 297: 16.
33. Qiao L, Schaack J, Shao J, (2006) Suppression of adiponectin gene expression by histone deacetylase inhibitor valproic acid. Endocrinology 147: 865-874.
34. Nogalska A, Sucajtys-Szulc E, Swierczynski J, (2005) Leptin decreases lipogenic enzyme gene expression through modification of SREBP-1c gene expression in white adipose tissue of aging rats. Metabolism 54: 1041-1047.
35. Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, et al. (2004) Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 306: 1383-1386.
36. Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, et al. (2006) Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312: 734-737.