Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2

Journal of Biological Chemistry

Volumn 277, Issue 39, 2002, Pages 36181-36187

  Xiao, Guozhi ^a,b   Jiang, Di ^a,b   Gopalakrishnan, Rajaram ^a,b   Franceschi, Renny T ^a,b,c  

^a School of Dentistry   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CHEMICAL ACTIVATION; DNA; ENZYMES; RNA;

OSTEOBLAST ACTIVITY;

GENES;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CORE BINDING FACTOR; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; OSTEOCALCIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; BONE CELL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE INDUCTION; GENE OVEREXPRESSION; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RNA ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; BLOTTING, WESTERN; BUTADIENES; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FIBROBLAST GROWTH FACTOR 2; GENE DELETION; GENES, REPORTER; GLUTATHIONE TRANSFERASE; LUCIFERASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; NITRILES; OSTEOBLASTS; OSTEOCALCIN; PHOSPHORYLATION; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA;

EID: 0037184027     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206057200     Document Type: Article

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