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Volumn 139, Issue , 2014, Pages 252-261

Effects of phytoestrogens and other plant-derived compounds on mesenchymal stem cells, bone maintenance and regeneration

Author keywords

Adipogenesis; Adipogenic shift; Mesenchymal stem cells; Osteogenesis; Phytoestrogens; Plant hormones

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; BETA CATENIN; COLLAGEN TYPE 1; DAIDZEIN; EPHRIN; ESTROGEN RECEPTOR; FATTY ACID BINDING PROTEIN 4; FRIZZLED PROTEIN; GENISTEIN; HYDROXYAPATITE; KAEMPFEROL; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDE Y; PARATHYROID HORMONE RECEPTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHYTOESTROGEN; PHYTOHORMONE; RESVERATROL; ROSIGLITAZONE; SAPONIN; SECRETED FRIZZLED RELATED PROTEIN 2; SEMAPHORIN; SIRTUIN 1; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; XANTHOHUMOL;

EID: 84889882595     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.12.006     Document Type: Review
Times cited : (56)

References (126)
  • 1
    • 0031955217 scopus 로고    scopus 로고
    • A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men
    • DOI 10.1359/jbmr.1998.13.5.763
    • B.L. Riggs, S. Khosla, and L.J. Melton III A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men Journal of Bone and Mineral Research 13 1998 763 773 (Pubitemid 28224192)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.5 , pp. 763-773
    • Riggs, B.L.1    Khosla, S.2    Melton III, L.J.3
  • 2
    • 0034842784 scopus 로고    scopus 로고
    • Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
    • DOI 10.1023/A:1011513223894
    • J. Justesen, K. Stenderup, E.N. Ebbesen, L. Mosekilde, T. Steiniche, and M. Kassem Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis Biogerontology 2 2001 165 171 (Pubitemid 32851325)
    • (2001) Biogerontology , vol.2 , Issue.3 , pp. 165-171
    • Justesen, J.1    Stenderup, K.2    Ebbesen, E.N.3    Mosekilde, L.4    Steiniche, T.5    Kassem, M.6
  • 3
    • 0033305457 scopus 로고    scopus 로고
    • The actions and interactions of sex steroids and growth factors/cytokines on the skeleton
    • T.C. Spelsberg, M. Subramaniam, B.L. Riggs, and S. Khosla The actions and interactions of sex steroids and growth factors/cytokines on the skeleton Molecular Endocrinology 13 1999 819 828 (Pubitemid 30645300)
    • (1999) Molecular Endocrinology , vol.13 , Issue.6 , pp. 819-828
    • Spelsberg, T.C.1    Subramaniam, M.2    Riggs, B.L.3    Khosla, S.4
  • 4
    • 0037668921 scopus 로고    scopus 로고
    • Postmenopausal femur bone loss: Effects of a low dose hormone replacement therapy
    • DOI 10.1016/S0378-5122(03)00141-5
    • M. Gambacciani, M. Ciaponi, B. Cappagli, P. Monteleone, C. Benussi, G. Bevilacqua, and A.R. Genazzani Postmenopausal femur bone loss: effects of a low dose hormone replacement therapy Maturitas 45 2003 175 183 (Pubitemid 36724872)
    • (2003) Maturitas , vol.45 , Issue.3 , pp. 175-183
    • Gambacciani, M.1    Ciaponi, M.2    Cappagli, B.3    Monteleone, P.4    Benussi, C.5    Bevilacqua, G.6    Genazzani, A.R.7
  • 5
    • 34248584700 scopus 로고    scopus 로고
    • The effects of short-term hormone replacement therapy on long-term bone mineral density
    • DOI 10.1080/13697130701370435, PII 778322129
    • E.T. Middleton, and S.A. Steel The effects of short-term hormone replacement therapy on long-term bone mineral density Climacteric 10 2007 257 263 (Pubitemid 46752433)
    • (2007) Climacteric , vol.10 , Issue.3 , pp. 257-263
    • Middleton, E.T.1    Steel, S.A.2
  • 6
    • 78649738304 scopus 로고    scopus 로고
    • The physiological actions of isoflavone phytoestrogens
    • L. Pilsakova, I. Riecansky, and F. Jagla The physiological actions of isoflavone phytoestrogens Physiological Research 59 2010 651 664
    • (2010) Physiological Research , vol.59 , pp. 651-664
    • Pilsakova, L.1    Riecansky, I.2    Jagla, F.3
  • 7
    • 0033896482 scopus 로고    scopus 로고
    • The therapeutic potential of phytoestrogens
    • H. Wiseman The therapeutic potential of phytoestrogens Expert Opinion on Investigational Drugs 9 2000 1829 1840 (Pubitemid 30639332)
    • (2000) Expert Opinion on Investigational Drugs , vol.9 , Issue.8 , pp. 1829-1840
    • Wiseman, H.1
  • 8
    • 0347186069 scopus 로고    scopus 로고
    • Recency and duration of postmenopausal hormone therapy: Effects on bone mineral density and fracture risk in the National Osteoporosis Risk Assessment (NORA) study
    • E. Barrett-Connor, L.E. Wehren, E.S. Siris, P. Miller, Y.T. Chen, T.A. Abbott III, M.L. Berger, A.C. Santora, and L.M. Sherwood Recency and duration of postmenopausal hormone therapy: effects on bone mineral density and fracture risk in the National Osteoporosis Risk Assessment (NORA) study Menopause 10 2003 412 419
    • (2003) Menopause , vol.10 , pp. 412-419
    • Barrett-Connor, E.1    Wehren, L.E.2    Siris, E.S.3    Miller, P.4    Chen, Y.T.5    Abbott III, T.A.6    Berger, M.L.7    Santora, A.C.8    Sherwood, L.M.9
  • 9
    • 0042018741 scopus 로고    scopus 로고
    • Breast cancer and hormone-replacement therapy in the Million Women Study
    • DOI 10.1016/S0140-6736(03)14065-2
    • V. Beral Collaborators, Breast cancer and hormone-replacement therapy in the Million Women Study The Lancet 362 2003 419 427 (Pubitemid 36999703)
    • (2003) Lancet , vol.362 , Issue.9382 , pp. 419-427
    • Beral, V.1
  • 11
    • 27144541559 scopus 로고    scopus 로고
    • Botanical and dietary supplements for menopausal symptoms: What works, what does not
    • DOI 10.1089/jwh.2005.14.634
    • S.E. Geller, and L. Studee Botanical and dietary supplements for menopausal symptoms: what works, what does not Journal of Women's Health (Larchmt) 14 2005 634 649 (Pubitemid 41508708)
    • (2005) Journal of Women's Health , vol.14 , Issue.7 , pp. 634-649
    • Geller, S.E.1    Studee, L.2
  • 13
    • 77950519110 scopus 로고    scopus 로고
    • Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells
    • A. Liedert, L. Wagner, L. Seefried, R. Ebert, F. Jakob, and A. Ignatius Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells Biochemical and Biophysical Research Communications 394 2010 755 759
    • (2010) Biochemical and Biophysical Research Communications , vol.394 , pp. 755-759
    • Liedert, A.1    Wagner, L.2    Seefried, L.3    Ebert, R.4    Jakob, F.5    Ignatius, A.6
  • 14
  • 16
    • 0032577990 scopus 로고    scopus 로고
    • Epidermal stem cells: Markers, patterning and the control of stem cell fate
    • DOI 10.1098/rstb.1998.0247
    • F.M. Watt Epidermal stem cells: markers, patterning and the control of stem cell fate Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 353 1998 831 837 (Pubitemid 28314365)
    • (1998) Philosophical Transactions of the Royal Society B: Biological Sciences , vol.353 , Issue.1370 , pp. 831-837
    • Watt, F.M.1
  • 17
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • DOI 10.1126/science.287.5457.1433
    • F.H. Gage Mammalian neural stem cells Science 287 2000 1433 1438 (Pubitemid 30127128)
    • (2000) Science , vol.287 , Issue.5457 , pp. 1433-1438
    • Gage, F.H.1
  • 19
    • 33745503987 scopus 로고    scopus 로고
    • Mesenchymal stem cells reside in virtually all post-natal organs and tissues
    • DOI 10.1242/jcs.02932
    • L. da Silva Meirelles, P.C. Chagastelles, and N.B. Nardi Mesenchymal stem cells reside in virtually all post-natal organs and tissues Journal of Cell Science 119 2006 2204 2213 (Pubitemid 43960310)
    • (2006) Journal of Cell Science , vol.119 , Issue.11 , pp. 2204-2213
    • Da Silva Meirelles, L.1    Chagastelles, P.C.2    Nardi, N.B.3
  • 20
    • 1542286220 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Clinical applications and biological characterization
    • DOI 10.1016/j.biocel.2003.11.001, PII S1357272503003625
    • F.P. Barry, and J.M. Murphy Mesenchymal stem cells: clinical applications and biological characterization International Journal of Biochemistry and Cell Biology 36 2004 568 584 (Pubitemid 38324589)
    • (2004) International Journal of Biochemistry and Cell Biology , vol.36 , Issue.4 , pp. 568-584
    • Barry, F.P.1    Murphy, J.M.2
  • 21
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
    • A. Muraglia, R. Cancedda, and R. Quarto Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model Journal of Cell Science 113 Pt 7 2000 1161 1166 (Pubitemid 30229533)
    • (2000) Journal of Cell Science , vol.113 , Issue.7 , pp. 1161-1166
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 23
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • DOI 10.1126/science.276.5309.71
    • D.J. Prockop Marrow stromal cells as stem cells for nonhematopoietic tissues Science 276 1997 71 74 (Pubitemid 27161245)
    • (1997) Science , vol.276 , Issue.5309 , pp. 71-74
    • Prockop, D.J.1
  • 24
    • 41549139755 scopus 로고    scopus 로고
    • Mesenchymal Stem Cells: Revisiting History, Concepts, and Assays
    • DOI 10.1016/j.stem.2008.03.002, PII S1934590908001148
    • P. Bianco, P.G. Robey, and P.J. Simmons Mesenchymal stem cells: revisiting history, concepts, and assays Cell Stem Cell 2 2008 313 319 (Pubitemid 351467394)
    • (2008) Cell Stem Cell , vol.2 , Issue.4 , pp. 313-319
    • Bianco, P.1    Robey, P.G.2    Simmons, P.J.3
  • 25
    • 24944503491 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Cell-based reconstructive therapy in orthopedics
    • DOI 10.1089/ten.2005.11.1198
    • A.I. Caplan Review: mesenchymal stem cells: cell-based reconstructive therapy in orthopedics Tissue Engineering 11 2005 1198 1211 (Pubitemid 41321423)
    • (2005) Tissue Engineering , vol.11 , Issue.7-8 , pp. 1198-1211
    • Caplan, A.I.1
  • 26
    • 20744456715 scopus 로고    scopus 로고
    • Newly discovered endocrine functions of white adipose tissue: Possible relevance in obesity-related diseases
    • DOI 10.1007/s00018-005-4555-z
    • A.W. Krug, and M. Ehrhart-Bornstein Newly discovered endocrine functions of white adipose tissue: possible relevance in obesity-related diseases Cellular and Molecular Life Sciences 62 2005 1359 1362 (Pubitemid 40853823)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.12 , pp. 1359-1362
    • Krug, A.W.1    Ehrhart-Bornstein, M.2
  • 27
    • 33745646751 scopus 로고    scopus 로고
    • Adipose tissue and adipokines - Energy regulation from the human perspective
    • P. Trayhurn, C. Bing, and I.S. Wood Adipose tissue and adipokines - energy regulation from the human perspective Journal of Nutrition 136 2006 1935S 1939S (Pubitemid 43973602)
    • (2006) Journal of Nutrition , vol.136 , Issue.7
    • Trayhurn, P.1    Bing, C.2    Wood, I.S.3
  • 28
    • 0042785118 scopus 로고    scopus 로고
    • Dietary phytoestrogens and their effect on bone: Evidence from in vitro and in vivo, human observational, and dietary intervention studies
    • K.D. Setchell, and E. Lydeking-Olsen Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies American Journal of Clinical Nutrition 78 2003 593S 609S (Pubitemid 40012554)
    • (2003) American Journal of Clinical Nutrition , vol.78 , Issue.3 SUPPL.
    • Setchell, K.D.R.1    Lydeking-Olsen, E.2
  • 29
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • DOI 10.1016/j.molmed.2004.12.004, PII S1471491404003132
    • T.J. Martin, and N.A. Sims Osteoclast-derived activity in the coupling of bone formation to resorption Trends in Molecular Medicine 11 2005 76 81 (Pubitemid 40193486)
    • (2005) Trends in Molecular Medicine , vol.11 , Issue.2 , pp. 76-81
    • Martin, T.J.1    Sims, N.A.2
  • 30
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: A sophisticated fibroblast under central surveillance
    • P. Ducy, T. Schinke, and G. Karsenty The osteoblast: a sophisticated fibroblast under central surveillance Science 289 2000 1501 1504
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 31
    • 0042204967 scopus 로고    scopus 로고
    • Transcriptional mechanisms in osteoblast differentiation and bone formation
    • DOI 10.1016/S0168-9525(03)00176-8
    • K. Nakashima, and B. de Crombrugghe Transcriptional mechanisms in osteoblast differentiation and bone formation Trends in Genetics 19 2003 458 466 (Pubitemid 36930029)
    • (2003) Trends in Genetics , vol.19 , Issue.8 , pp. 458-466
    • Nakashima, K.1    De Crombrugghe, B.2
  • 32
    • 0034737742 scopus 로고    scopus 로고
    • Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase
    • DOI 10.1074/jbc.275.13.9645
    • R.K. Jaiswal, N. Jaiswal, S.P. Bruder, G. Mbalaviele, D.R. Marshak, and M.F. Pittenger Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase Journal of Biological Chemistry 275 2000 9645 9652 (Pubitemid 30185197)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.13 , pp. 9645-9652
    • Jaiswal, R.K.1    Jaiswal, N.2    Bruder, S.P.3    Mbalaviele, G.4    Marshak, D.R.5    Pittenger, M.F.6
  • 34
    • 0037184027 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2
    • G. Xiao, D. Jiang, R. Gopalakrishnan, and R.T. Franceschi Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2 Journal of Biological Chemistry 277 2002 36181 36187
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 36181-36187
    • Xiao, G.1    Jiang, D.2    Gopalakrishnan, R.3    Franceschi, R.T.4
  • 35
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation
    • DOI 10.1016/S0092-8674(01)00622-5
    • K. Nakashima, X. Zhou, G. Kunkel, Z. Zhang, J.M. Deng, R.R. Behringer, and B. de Crombrugghe The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation Cell 108 2002 17 29 (Pubitemid 34137009)
    • (2002) Cell , vol.108 , Issue.1 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    De Crombrugghe, B.7
  • 37
    • 0032879350 scopus 로고    scopus 로고
    • Differentiation of human marrow stromal precursor cells: Bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation
    • DOI 10.1359/jbmr.1999.14.9.1522
    • F. Gori, T. Thomas, K.C. Hicok, T.C. Spelsberg, and B.L. Riggs Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation Journal of Bone and Mineral Research 14 1999 1522 1535 (Pubitemid 29416678)
    • (1999) Journal of Bone and Mineral Research , vol.14 , Issue.9 , pp. 1522-1535
    • Gori, F.1    Thomas, T.2    Hicok, K.C.3    Spelsberg, T.C.4    Riggs, B.L.5
  • 38
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • DOI 10.1146/annurev.cellbio.20.010403.113126
    • C.Y. Logan, and R. Nusse The Wnt signaling pathway in development and disease Annual Review of Cell and Developmental Biology 20 2004 781 810 (Pubitemid 39488658)
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 39
    • 0033590172 scopus 로고    scopus 로고
    • 2+ pathways
    • J.R. Miller, A.M. Hocking, J.D. Brown, and R.T. Moon Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways Oncogene 18 1999 7860 7872 (Pubitemid 30066232)
    • (1999) Oncogene , vol.18 , Issue.55 , pp. 7860-7872
    • Miller, J.R.1    Hocking, A.M.2    Brown, J.D.3    Moon, R.T.4
  • 41
    • 84872185847 scopus 로고    scopus 로고
    • Signaling pathways affecting skeletal health
    • (Epub ahead of print)
    • P.J. Marie Signaling pathways affecting skeletal health Current Osteoporosis Reports 2012 (Epub ahead of print)
    • (2012) Current Osteoporosis Reports
    • Marie, P.J.1
  • 43
    • 0029977717 scopus 로고    scopus 로고
    • Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins
    • G.K. Hunter, P.V. Hauschka, A.R. Poole, L.C. Rosenberg, and H.A. Goldberg Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins Biochemical Journal 317 Pt 1 1996 59 64 (Pubitemid 26238329)
    • (1996) Biochemical Journal , vol.317 , Issue.1 , pp. 59-64
    • Hunter, G.K.1    Hauschka, P.V.2    Poole, A.R.3    Rosenberg, L.C.4    Goldberg, H.A.5
  • 44
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived hormone adiponectin in human disease
    • DOI 10.1530/eje.0.1480293
    • J.J. Diez, and P. Iglesias The role of the novel adipocyte-derived hormone adiponectin in human disease European Journal of Endocrinology 148 2003 293 300 (Pubitemid 36410714)
    • (2003) European Journal of Endocrinology , vol.148 , Issue.3 , pp. 293-300
    • Diez, J.J.1    Iglesias, P.2
  • 47
    • 0036134008 scopus 로고    scopus 로고
    • Adipogenesis: Forces that tip the scales
    • DOI 10.1016/S1043-2760(01)00517-3, PII S1043276001005173
    • O.A. MacDougald, and S. Mandrup Adipogenesis: forces that tip the scales Trends in Endocrinology and Metabolism 13 2002 5 11 (Pubitemid 36734009)
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , Issue.1 , pp. 5-11
    • MacDougald, O.A.1    Mandrup, S.2
  • 49
    • 0027465113 scopus 로고
    • Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes
    • B.M. Spiegelman, L. Choy, G.S. Hotamisligil, R.A. Graves, and P. Tontonoz Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes Journal of Biological Chemistry 268 1993 6823 6826 (Pubitemid 23105553)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.10 , pp. 6823-6826
    • Spiegelman, B.M.1    Choy, L.2    Hotamisligil, G.S.3    Graves, R.A.4    Tontonoz, P.5
  • 53
    • 0033083803 scopus 로고    scopus 로고
    • Cross-regulation of C/EBPα and PPARγ controls the transcriptional pathway of adipogenesis and insulin sensitivity
    • DOI 10.1016/S1097-2765(00)80306-8
    • Z. Wu, E.D. Rosen, R. Brun, S. Hauser, G. Adelmant, A.E. Troy, C. McKeon, G.J. Darlington, and B.M. Spiegelman Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity Molecular Cell 3 1999 151 158 (Pubitemid 29292616)
    • (1999) Molecular Cell , vol.3 , Issue.2 , pp. 151-158
    • Wu, Z.1    Rosen, E.D.2    Brun, R.3    Hauser, S.4    Adelmant, G.5    Troy, A.E.6    McKeon, C.7    Darlington, G.J.8    Spiegelman, B.M.9
  • 54
    • 0024728355 scopus 로고
    • Regulation of gene expression during adipocyte differentiation: A review
    • H.R. Gaskins, G.J. Hausman, and R.J. Martin Regulation of gene expression during adipocyte differentiation: a review Journal of Animal Science 67 1989 2263 2272
    • (1989) Journal of Animal Science , vol.67 , pp. 2263-2272
    • Gaskins, H.R.1    Hausman, G.J.2    Martin, R.J.3
  • 55
    • 0026718865 scopus 로고
    • Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures
    • J.N. Beresford, J.H. Bennett, C. Devlin, P.S. Leboy, and M.E. Owen Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures Journal of Cell Science 102 Pt 2 1992 341 351
    • (1992) Journal of Cell Science , vol.102 , Issue.PART 2 , pp. 341-351
    • Beresford, J.N.1    Bennett, J.H.2    Devlin, C.3    Leboy, P.S.4    Owen, M.E.5
  • 57
    • 14244250617 scopus 로고    scopus 로고
    • Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation
    • DOI 10.1210/en.2004-0735
    • A.A. Ali, R.S. Weinstein, S.A. Stewart, A.M. Parfitt, S.C. Manolagas, and R.L. Jilka Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation Endocrinology 146 2005 1226 1235 (Pubitemid 40289310)
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1226-1235
    • Ali, A.A.1    Weinstein, R.S.2    Stewart, S.A.3    Parfitt, A.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 58
    • 0036090467 scopus 로고    scopus 로고
    • Divergent effects of selective peroxisome proliferator-activated receptor-γ2 ligands on adipocyte versus osteoblast differentiation
    • DOI 10.1210/en.143.6.2376
    • B. Lecka-Czernik, E.J. Moerman, D.F. Grant, J.M. Lehmann, S.C. Manolagas, and R.L. Jilka Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation Endocrinology 143 2002 2376 2384 (Pubitemid 34521584)
    • (2002) Endocrinology , vol.143 , Issue.6 , pp. 2376-2384
    • Lecka-Czernik, B.1    Moerman, E.J.2    Grant, D.F.3    Lehmann, J.M.4    Manolagas, S.C.5    Jilka, R.L.6
  • 59
    • 34147154970 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: A randomized, controlled trial
    • DOI 10.1210/jc.2006-2646
    • A. Grey, M. Bolland, G. Gamble, D. Wattie, A. Horne, J. Davidson, and I.R. Reid The peroxisome proliferator-activated receptor-γ agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial Journal of Clinical Endocrinology and Metabolism 92 2007 1305 1310 (Pubitemid 46556402)
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.4 , pp. 1305-1310
    • Grey, A.1    Bolland, M.2    Gamble, G.3    Wattie, D.4    Horne, A.5    Davidson, J.6    Reid, I.R.7
  • 60
    • 0041766341 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-γ inhibits differentiation of preosteoblasts
    • DOI 10.1016/S0022-2143(03)00058-1
    • E. Khan, and Y. Abu-amer Activation of peroxisome proliferator-activated receptor-γ inhibits differentiation of preosteoblasts Journal of Laboratory and Clinical Medicine 142 2003 29 34 (Pubitemid 36930414)
    • (2003) Journal of Laboratory and Clinical Medicine , vol.142 , Issue.1 , pp. 29-34
    • Khan, E.1    Abu-Amer, Y.2
  • 63
    • 0037474465 scopus 로고    scopus 로고
    • Activated β-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2 mediated signal transduction
    • DOI 10.1016/S0006-291X(02)02951-0
    • G. Bain, T. Muller, X. Wang, and J. Papkoff Activated beta-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2 mediated signal transduction Biochemical and Biophysical Research Communications 301 2003 84 91 (Pubitemid 36268851)
    • (2003) Biochemical and Biophysical Research Communications , vol.301 , Issue.1 , pp. 84-91
    • Bain, G.1    Muller, T.2    Wang, X.3    Papkoff, J.4
  • 64
    • 0142241118 scopus 로고    scopus 로고
    • BMP-2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop
    • DOI 10.1359/jbmr.2003.18.10.1842
    • G. Rawadi, B. Vayssiere, F. Dunn, R. Baron, and S. Roman-Roman BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop Journal of Bone and Mineral Research 18 2003 1842 1853 (Pubitemid 37322562)
    • (2003) Journal of Bone and Mineral Research , vol.18 , Issue.10 , pp. 1842-1853
    • Rawadi, G.1    Vayssiere, B.2    Dunn, F.3    Baron, R.4    Roman-Roman, S.5
  • 69
    • 15744378328 scopus 로고    scopus 로고
    • Wnt5b partially inhibits canonical Wnt/β-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes
    • DOI 10.1016/j.bbrc.2005.03.007
    • A. Kanazawa, S. Tsukada, M. Kamiyama, T. Yanagimoto, M. Nakajima, and S. Maeda Wnt5b partially inhibits canonical Wnt/beta-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes Biochemical and Biophysical Research Communications 330 2005 505 510 (Pubitemid 40417673)
    • (2005) Biochemical and Biophysical Research Communications , vol.330 , Issue.2 , pp. 505-510
    • Kanazawa, A.1    Tsukada, S.2    Kamiyama, M.3    Yanagimoto, T.4    Nakajima, M.5    Maeda, S.6
  • 70
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • P. Meunier, J. Aaron, C. Edouard, and G. Vignon Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies Clinical Orthopaedics and Related Research 80 1971 147 154
    • (1971) Clinical Orthopaedics and Related Research , vol.80 , pp. 147-154
    • Meunier, P.1    Aaron, J.2    Edouard, C.3    Vignon, G.4
  • 72
    • 0031907248 scopus 로고    scopus 로고
    • Age-related marrow conversion in the proximal metaphysis of the femur: Evaluation with T1-weighted MR imaging
    • K.H. Koo, R. Dussault, P. Kaplan, R. Kim, I.O. Ahn, J. Christopher, H.R. Song, and G.J. Wang Age-related marrow conversion in the proximal metaphysis of the femur: evaluation with T1-weighted MR imaging Radiology 206 1998 745 748 (Pubitemid 28128524)
    • (1998) Radiology , vol.206 , Issue.3 , pp. 745-748
    • Koo, K.-H.1    Dussault, R.2    Kaplan, P.3    Kim, R.4    Ahn, I.-O.5    Christopher, J.6    Song, H.-R.7    Wang, G.-J.8
  • 74
    • 34249011772 scopus 로고    scopus 로고
    • Plasticity in adipogenesis and osteogenesis of human mesenchymal stem cells
    • DOI 10.1016/j.mce.2007.03.004, PII S0303720707001281
    • T. Schilling, U. Nöth, L. Klein-Hitpass, F. Jakob, and N. Schütze Plasticity in adipogenesis and osteogenesis of human mesenchymal stem cells Molecular and Cellular Endocrinology 271 2007 1 17 (Pubitemid 46803047)
    • (2007) Molecular and Cellular Endocrinology , vol.271 , Issue.1-2 , pp. 1-17
    • Schilling, T.1    Noth, U.2    Klein-Hitpass, L.3    Jakob, F.4    Schutze, N.5
  • 75
    • 4944257952 scopus 로고    scopus 로고
    • Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow
    • DOI 10.1096/fj.03-1100fje
    • L. Song, and R.S. Tuan Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow FASEB Journal 18 2004 980 982 (Pubitemid 39561498)
    • (2004) FASEB Journal , vol.18 , Issue.9 , pp. 980-982
    • Song, L.1    Tuan, R.S.2
  • 77
    • 84864804886 scopus 로고    scopus 로고
    • Association of circulating sclerostin levels with fat mass and metabolic disease - Related markers in Japanese postmenopausal women
    • (Epub ahead of print)
    • T. Urano, M. Shiraki, Y. Ouchi, and S. Inoue Association of circulating sclerostin levels with fat mass and metabolic disease - related markers in Japanese postmenopausal women Journal of Clinical Endocrinology and Metabolism 2012 (Epub ahead of print)
    • (2012) Journal of Clinical Endocrinology and Metabolism
    • Urano, T.1    Shiraki, M.2    Ouchi, Y.3    Inoue, S.4
  • 79
    • 0032924683 scopus 로고    scopus 로고
    • Interconversion potential of cloned human marrow adipocytes in vitro
    • DOI 10.1016/S8756-3282(99)00084-8, PII S8756328299000848
    • S.R. Park, R.O. Oreffo, and J.T. Triffitt Interconversion potential of cloned human marrow adipocytes in vitro Bone 24 1999 549 554 (Pubitemid 29234067)
    • (1999) Bone , vol.24 , Issue.6 , pp. 549-554
    • Park, S.R.1    Oreffo, R.O.C.2    Triffitt, J.T.3
  • 82
    • 0036090574 scopus 로고    scopus 로고
    • Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) α or β
    • DOI 10.1210/en.143.6.2349
    • R. Okazaki, D. Inoue, M. Shibata, M. Saika, S. Kido, H. Ooka, H. Tomiyama, Y. Sakamoto, and T. Matsumoto Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta Endocrinology 143 2002 2349 2356 (Pubitemid 34521581)
    • (2002) Endocrinology , vol.143 , Issue.6 , pp. 2349-2356
    • Okazaki, R.Y.O.1    Inoue, D.2    Shibata, M.3    Saika, M.4    Kido, S.5    Ooka, H.6    Tomiyama, H.7    Sakamoto, Y.8    Matsumoto, T.9
  • 83
    • 10744224568 scopus 로고    scopus 로고
    • The Phytoestrogen Genistein Enhances Osteogenesis and Represses Adipogenic Differentiation of Human Primary Bone Marrow Stromal Cells
    • DOI 10.1210/en.2003-1014
    • M. Heim, O. Frank, G. Kampmann, N. Sochocky, T. Pennimpede, P. Fuchs, W. Hunziker, P. Weber, I. Martin, and I. Bendik The phytoestrogen genistein enhances osteogenesis and represses adipogenic differentiation of human primary bone marrow stromal cells Endocrinology 145 2004 848 859 (Pubitemid 38183829)
    • (2004) Endocrinology , vol.145 , Issue.2 , pp. 848-859
    • Heim, M.1    Frank, O.2    Kampmann, G.3    Sochocky, N.4    Pennimpede, T.5    Fuchs, P.6    Hunziker, W.7    Weber, P.8    Martin, I.9    Bendik, I.10
  • 85
    • 0031089258 scopus 로고    scopus 로고
    • A comparative survey of leguminous plants as sources of the isoflavones, genistein and daidzein: Implications for human nutrition and health
    • P.B. Kaufman, J.A. Duke, H. Brielmann, J. Boik, and J.E. Hoyt A comparative survey of leguminous plants as sources of the isoflavones, genistein and daidzein: implications for human nutrition and health Journal of Alternative and Complementary Medicine 3 1997 7 12 (Pubitemid 127532077)
    • (1997) Journal of Alternative and Complementary Medicine , vol.3 , Issue.1 , pp. 7-12
    • Kaufman, P.B.1    Duke, J.A.2    Brielmann, H.3    Boik, J.4    Hoyt, J.E.5
  • 87
    • 24744447970 scopus 로고    scopus 로고
    • Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts
    • X.H. Li, J.C. Zhang, S.F. Sui, and M.S. Yang Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts Acta Pharmacologica Sinica 26 2005 1081 1086
    • (2005) Acta Pharmacologica Sinica , vol.26 , pp. 1081-1086
    • Li, X.H.1    Zhang, J.C.2    Sui, S.F.3    Yang, M.S.4
  • 88
    • 78049453745 scopus 로고    scopus 로고
    • Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/beta-catenin signalling or lipolysis
    • M.H. Kim, J.S. Park, M.S. Seo, J.W. Jung, Y.S. Lee, and K.S. Kang Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/beta-catenin signalling or lipolysis Cell Proliferation 43 2010 594 605
    • (2010) Cell Proliferation , vol.43 , pp. 594-605
    • Kim, M.H.1    Park, J.S.2    Seo, M.S.3    Jung, J.W.4    Lee, Y.S.5    Kang, K.S.6
  • 89
    • 57449103168 scopus 로고    scopus 로고
    • Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells
    • C.M. Bäckesjö, Y. Li, U. Lindgren, and L.A. Haldosén Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells Cells Tissues Organs 189 2009 93 97
    • (2009) Cells Tissues Organs , vol.189 , pp. 93-97
    • Bäckesjö, C.M.1    Li, Y.2    Lindgren, U.3    Haldosén, L.A.4
  • 90
    • 70349472930 scopus 로고    scopus 로고
    • Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells
    • H. Zhou, L. Shang, X. Li, X. Zhang, G. Gao, C. Guo, B. Chen, Q. Liu, Y. Gong, and C. Shao Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells Experimental Cell Research 315 2009 2953 2962
    • (2009) Experimental Cell Research , vol.315 , pp. 2953-2962
    • Zhou, H.1    Shang, L.2    Li, X.3    Zhang, X.4    Gao, G.5    Guo, C.6    Chen, B.7    Liu, Q.8    Gong, Y.9    Shao, C.10
  • 91
    • 84859974018 scopus 로고    scopus 로고
    • Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: Potential role of Runx2 deacetylation
    • M. Shakibaei, P. Shayan, F. Busch, C. Aldinger, C. Buhrmann, C. Lueders, and A. Mobasheri Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation PLoS ONE 7 2012 e35712
    • (2012) PLoS ONE , vol.7 , pp. 35712
    • Shakibaei, M.1    Shayan, P.2    Busch, F.3    Aldinger, C.4    Buhrmann, C.5    Lueders, C.6    Mobasheri, A.7
  • 92
    • 77953521260 scopus 로고    scopus 로고
    • Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis
    • I. Mader, M. Wabitsch, K.-M. Debatin, P. Fischer-Posovszky, and S. Fulda Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis The FASEB Journal 24 2010 1997 2009
    • (2010) The FASEB Journal , vol.24 , pp. 1997-2009
    • Mader, I.1    Wabitsch, M.2    Debatin, K.-M.3    Fischer-Posovszky, P.4    Fulda, S.5
  • 94
    • 79952697425 scopus 로고    scopus 로고
    • Panax notoginseng saponins promotes proliferation and osteogenic differentiation of rat bone marrow stromal cells
    • X.D. Li, J.S. Wang, B. Chang, B. Chen, C. Guo, G.Q. Hou, D.Y. Huang, and S.X. Du Panax notoginseng saponins promotes proliferation and osteogenic differentiation of rat bone marrow stromal cells Journal of Ethnopharmacology 134 2011 268 274
    • (2011) Journal of Ethnopharmacology , vol.134 , pp. 268-274
    • Li, X.D.1    Wang, J.S.2    Chang, B.3    Chen, B.4    Guo, C.5    Hou, G.Q.6    Huang, D.Y.7    Du, S.X.8
  • 95
    • 84864398591 scopus 로고    scopus 로고
    • Osteoprotective effects of Cimicifuga racemosa and its triterpene-saponins are responsible for reduction of bone marrow fat
    • D. Seidlova-Wuttke, G. Stecher, M. Kammann, J. Haunschild, N. Eder, V. Stahnke, J. Wessels, and W. Wuttke Osteoprotective effects of Cimicifuga racemosa and its triterpene-saponins are responsible for reduction of bone marrow fat Phytomedicine 19 2012 855 860
    • (2012) Phytomedicine , vol.19 , pp. 855-860
    • Seidlova-Wuttke, D.1    Stecher, G.2    Kammann, M.3    Haunschild, J.4    Eder, N.5    Stahnke, V.6    Wessels, J.7    Wuttke, W.8
  • 96
    • 82955189145 scopus 로고    scopus 로고
    • TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol
    • M.R. Byun, H. Jeong, S.J. Bae, A.R. Kim, E.S. Hwang, and J.-H. Hong TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol Bone 50 2012 364 372
    • (2012) Bone , vol.50 , pp. 364-372
    • Byun, M.R.1    Jeong, H.2    Bae, S.J.3    Kim, A.R.4    Hwang, E.S.5    Hong, J.-H.6
  • 98
    • 67749127905 scopus 로고    scopus 로고
    • Coumestrol promotes proliferation and osteoblastic differentiation in rat bone marrow stromal cells
    • X.-t. Wu, B. Wang, and J.-n. Wei Coumestrol promotes proliferation and osteoblastic differentiation in rat bone marrow stromal cells Journal of Biomedical Materials Research Part B Applied Biomaterials 90B 2009 621 628
    • (2009) Journal of Biomedical Materials Research Part B Applied Biomaterials , vol.90 B , pp. 621-628
    • Wu, X.-T.1    Wang, B.2
  • 99
    • 53749102440 scopus 로고    scopus 로고
    • Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway
    • X.-z. Lu, J.-h. Wang, X. Wu, L. Zhou, L. Wang, X.-w. Zhang, K.-j. Cao, and J. Huang Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway Acta Pharmacologica Sinica 29 2008 1209 1214
    • (2008) Acta Pharmacologica Sinica , vol.29 , pp. 1209-1214
    • Wu, X.1    Zhou, L.2    Wang, L.3    Huang, J.4
  • 100
    • 77953884088 scopus 로고    scopus 로고
    • Platycodin D inhibits adipogenesis of 3T3-L1 cells by modulating Kruppel-like factor 2 and peroxisome proliferator-activated receptor gamma
    • H. Lee, R. Kang, Y.S. Kim, S.I. Chung, and Y. Yoon Platycodin D inhibits adipogenesis of 3T3-L1 cells by modulating Kruppel-like factor 2 and peroxisome proliferator-activated receptor gamma Phytotherapy Research 24 Suppl. 2 2010 S161 S167
    • (2010) Phytotherapy Research , vol.24 , Issue.SUPPL. 2
    • Lee, H.1    Kang, R.2    Kim, Y.S.3    Chung, S.I.4    Yoon, Y.5
  • 101
    • 34247608127 scopus 로고    scopus 로고
    • Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells
    • DOI 10.1016/j.mce.2007.01.017, PII S0303720707000408
    • H. Zhou, X. Yang, N. Wang, Y. Zhang, and G. Cai Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells Molecular and Cellular Endocrinology 270 2007 17 22 (Pubitemid 46670545)
    • (2007) Molecular and Cellular Endocrinology , vol.270 , Issue.1-2 , pp. 17-22
    • Zhou, H.1    Yang, X.2    Wang, N.3    Zhang, Y.4    Cai, G.5
  • 102
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors and α and β
    • DOI 10.1210/en.138.3.863
    • G.G. Kuiper, B. Carlsson, K. Grandien, E. Enmark, J. Haggblad, S. Nilsson, and J.A. Gustafsson Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta Endocrinology 138 1997 863 870 (Pubitemid 27089735)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.J.M.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.-A.7
  • 104
    • 82155173499 scopus 로고    scopus 로고
    • The G-protein-coupled estrogen receptor GPER in health and disease
    • E.R. Prossnitz, and M. Barton The G-protein-coupled estrogen receptor GPER in health and disease Nature Reviews Endocrinology 7 2011 715 726
    • (2011) Nature Reviews Endocrinology , vol.7 , pp. 715-726
    • Prossnitz, E.R.1    Barton, M.2
  • 105
    • 43849105081 scopus 로고    scopus 로고
    • The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone
    • T.J. Heino, A.S. Chagin, and L. Savendahl The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone Journal of Endocrinology 197 2008 R1 R6
    • (2008) Journal of Endocrinology , vol.197
    • Heino, T.J.1    Chagin, A.S.2    Savendahl, L.3
  • 107
    • 84861366499 scopus 로고    scopus 로고
    • Genistein regulates the IL-1 beta induced activation of MAPKs in human periodontal ligament cells through G protein-coupled receptor 30
    • L.J. Luo, F. Liu, Z.K. Lin, Y.F. Xie, J.L. Xu, Q.C. Tong, and R. Shu Genistein regulates the IL-1 beta induced activation of MAPKs in human periodontal ligament cells through G protein-coupled receptor 30 Archives of Biochemistry and Biophysics 522 2012 9 16
    • (2012) Archives of Biochemistry and Biophysics , vol.522 , pp. 9-16
    • Luo, L.J.1    Liu, F.2    Lin, Z.K.3    Xie, Y.F.4    Xu, J.L.5    Tong, Q.C.6    Shu, R.7
  • 111
    • 74249099068 scopus 로고    scopus 로고
    • Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype
    • J. Gracia-Sancho, G. Villarreal Jr., Y. Zhang, and G. Garcia-Cardena Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype Cardiovascular Research 85 2010 514 519
    • (2010) Cardiovascular Research , vol.85 , pp. 514-519
    • Gracia-Sancho, J.1    Villarreal, Jr.G.2    Zhang, Y.3    Garcia-Cardena, G.4
  • 112
    • 34347235843 scopus 로고    scopus 로고
    • Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein α and peroxisome proliferator-activated receptor γ
    • DOI 10.1074/jbc.M700030200
    • S. Kang, C.N. Bennett, I. Gerin, L.A. Rapp, K.D. Hankenson, and O.A. Macdougald Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma Journal of Biological Chemistry 282 2007 14515 14524 (Pubitemid 47100486)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.19 , pp. 14515-14524
    • Kang, S.1    Bennett, C.N.2    Gerin, I.3    Rapp, L.A.4    Hankenson, K.D.5    MacDougald, O.A.6
  • 114
    • 55549148757 scopus 로고    scopus 로고
    • Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells
    • Y. Li, Z. Wang, D. Kong, R. Li, S.H. Sarkar, and F.H. Sarkar Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells Journal of Biological Chemistry 283 2008 27707 27716
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 27707-27716
    • Li, Y.1    Wang, Z.2    Kong, D.3    Li, R.4    Sarkar, S.H.5    Sarkar, F.H.6
  • 115
    • 84858963986 scopus 로고    scopus 로고
    • Dynamic expression of DKK1 protein in the process whereby Epimedium-derived flavonoids up-regulate osteogenic and down-regulate adipogenic differentiation of bone marrow stromal cells in ovariectomized rats
    • Y.X. Xu, B. Xu, C.L. Wu, Y. Wu, P.J. Tong, and L.W. Xiao Dynamic expression of DKK1 protein in the process whereby Epimedium-derived flavonoids up-regulate osteogenic and down-regulate adipogenic differentiation of bone marrow stromal cells in ovariectomized rats Orthopaedic Surgery 3 2011 119 126
    • (2011) Orthopaedic Surgery , vol.3 , pp. 119-126
    • Xu, Y.X.1    Xu, B.2    Wu, C.L.3    Wu, Y.4    Tong, P.J.5    Xiao, L.W.6
  • 116
    • 12844271254 scopus 로고    scopus 로고
    • The emerging therapeutic potential of sirtuin-interacting drugs: From cell death to lifespan extension
    • DOI 10.1016/j.tips.2004.12.009, PII S0165614704003232
    • M. Porcu, and A. Chiarugi The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension Trends in Pharmacological Sciences 26 2005 94 103 (Pubitemid 40170172)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.2 , pp. 94-103
    • Porcu, M.1    Chiarugi, A.2
  • 118
    • 34848922689 scopus 로고    scopus 로고
    • Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture
    • Q.C. Liao, Z.S. Xiao, Y.F. Qin, and H.H. Zhou Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture Acta Pharmacologica Sinica 28 2007 1597 1602
    • (2007) Acta Pharmacologica Sinica , vol.28 , pp. 1597-1602
    • Liao, Q.C.1    Xiao, Z.S.2    Qin, Y.F.3    Zhou, H.H.4
  • 119
    • 50249160525 scopus 로고    scopus 로고
    • Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity
    • Q.C. Liao, Y.L. Li, Y.F. Qin, L.D. Quarles, K.K. Xu, R. Li, H.H. Zhou, and Z.S. Xiao Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity Journal of Cellular Biochemistry 104 2008 1853 1864
    • (2008) Journal of Cellular Biochemistry , vol.104 , pp. 1853-1864
    • Liao, Q.C.1    Li, Y.L.2    Qin, Y.F.3    Quarles, L.D.4    Xu, K.K.5    Li, R.6    Zhou, H.H.7    Xiao, Z.S.8
  • 121
    • 35548970288 scopus 로고    scopus 로고
    • Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation
    • DOI 10.1016/j.phymed.2007.04.003, PII S094471130700061X
    • Z. Dai, Y. Li, L.D. Quarles, T. Song, W. Pan, H. Zhou, and Z. Xiao Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation Phytomedicine 14 2007 806 814 (Pubitemid 350017876)
    • (2007) Phytomedicine , vol.14 , Issue.12 , pp. 806-814
    • Dai, Z.1    Li, Y.2    Quarles, L.D.3    Song, T.4    Pan, W.5    Zhou, H.6    Xiao, Z.7
  • 122
    • 0037436792 scopus 로고    scopus 로고
    • Pharmacology of Cimicifuga racemosa extract BNO 1055 in rats: Bone, fat and uterus
    • D. Seidlova-Wuttke, H. Jarry, T. Becker, V. Christoffel, and W. Wuttke Pharmacology of Cimicifuga racemosa extract BNO 1055 in rats: bone, fat and uterus Maturitas 44 Suppl. 1 2003 S39 S50
    • (2003) Maturitas , vol.44 , Issue.SUPPL. 1
    • Seidlova-Wuttke, D.1    Jarry, H.2    Becker, T.3    Christoffel, V.4    Wuttke, W.5
  • 123
    • 0031741906 scopus 로고    scopus 로고
    • Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones
    • K.D. Setchell Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones American Journal of Clinical Nutrition 68 1998 1333S 1346S (Pubitemid 28550909)
    • (1998) American Journal of Clinical Nutrition , vol.68 , Issue.6 SUPPL.
    • Setchell, K.D.R.1
  • 124
    • 48749084087 scopus 로고    scopus 로고
    • Comparative activities of daidzein metabolites, equol and O-desmethylangolensin, on bone mineral density and lipid metabolism in ovariectomized mice and in osteoclast cell cultures
    • T. Ohtomo, M. Uehara, J.L. Penalvo, H. Adlercreutz, S. Katsumata, K. Suzuki, K. Takeda, R. Masuyama, and Y. Ishimi Comparative activities of daidzein metabolites, equol and O-desmethylangolensin, on bone mineral density and lipid metabolism in ovariectomized mice and in osteoclast cell cultures European Journal of Nutrition 47 2008 273 279
    • (2008) European Journal of Nutrition , vol.47 , pp. 273-279
    • Ohtomo, T.1    Uehara, M.2    Penalvo, J.L.3    Adlercreutz, H.4    Katsumata, S.5    Suzuki, K.6    Takeda, K.7    Masuyama, R.8    Ishimi, Y.9
  • 125
    • 77957935850 scopus 로고    scopus 로고
    • Mechanical activation of beta-catenin regulates phenotype in adult murine marrow-derived mesenchymal stem cells
    • N. Case, Z. Xie, B. Sen, M. Styner, M. Zou, C. O'Conor, M. Horowitz, and J. Rubin Mechanical activation of beta-catenin regulates phenotype in adult murine marrow-derived mesenchymal stem cells Journal of Orthopaedic Research 28 2010 1531 1538
    • (2010) Journal of Orthopaedic Research , vol.28 , pp. 1531-1538
    • Case, N.1    Xie, Z.2    Sen, B.3    Styner, M.4    Zou, M.5    O'Conor, C.6    Horowitz, M.7    Rubin, J.8
  • 126
    • 84867143621 scopus 로고    scopus 로고
    • Preventive effects of phytoestrogens against postmenopausal osteoporosis as compared to the available therapeutic choices: An overview
    • A.F. Al-Anazi, V.F. Qureshi, K. Javaid, and S. Qureshi Preventive effects of phytoestrogens against postmenopausal osteoporosis as compared to the available therapeutic choices: an overview Journal of Natural Science, Biology and Medicine 2 2011 154 163
    • (2011) Journal of Natural Science, Biology and Medicine , vol.2 , pp. 154-163
    • Al-Anazi, A.F.1    Qureshi, V.F.2    Javaid, K.3    Qureshi, S.4


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