The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts

Journal of Bone and Mineral Metabolism

Volumn 26, Issue 6, 2008, Pages 551-560

  Nam, Tae Wook ^a   Yoo, Chong Il ^a   Kim, Hui Taek ^a   Kwon, Chae Hwa ^b   Park, Ji Yeon ^b   Kim, Yong Keun ^b  

^a Pusan National University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

Author keywords

Apoptosis; Flavonoid; MAPK; Migration; Osteoblastic cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CASPASE 3; FLAVONOID; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; QUERCETIN; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; ANTIOXIDANT; BAICALEIN; CASPASE; ENZYME INHIBITOR; FLAVANONE DERIVATIVE; OXIDIZING AGENT; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DEPOLARIZATION; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; WESTERN BLOTTING; ANIMAL; CELL MOTION; CELL STRAIN 3T3; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

3T3 CELLS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL MOVEMENT; CELL SURVIVAL; ENZYME INHIBITORS; FLAVANONES; FLAVONOIDS; HYDROGEN PEROXIDE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOBLASTS; OXIDANTS; QUERCETIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58149235546     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-008-0864-2     Document Type: Article

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