-
1
-
-
0028180315
-
The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
-
Kingsley DM., The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 1994; 8: 133-146.
-
(1994)
Genes Dev.
, vol.8
, pp. 133-146
-
-
Kingsley, D.M.1
-
3
-
-
34248355601
-
Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells
-
DOI 10.1002/jor.20359
-
Luu HH, Song WX, Luo X, et al. Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res. 2007; 25: 665-677. (Pubitemid 46730519)
-
(2007)
Journal of Orthopaedic Research
, vol.25
, Issue.5
, pp. 665-677
-
-
Luu, H.H.1
Song, W.-X.2
Luo, X.3
Manning, D.4
Luo, J.5
Deng, Z.-L.6
Sharff, K.A.7
Montag, A.G.8
Haydon, R.C.9
He, T.-C.10
-
4
-
-
0030071490
-
Bone morphogenetic protein-2: Biology and applications
-
Riley EH, Lane JM, Urist MR, Lyons KM, Lieberman JR., Bone morphogenetic protein 2: biology and applications. Clin Orthop Relat Res. 1996; 324: 39-46. (Pubitemid 26071749)
-
(1996)
Clinical Orthopaedics and Related Research
, Issue.324
, pp. 39-46
-
-
Riley, E.H.1
Lane, J.M.2
Urist, M.R.3
Lyons, K.M.4
Lieberman, J.R.5
-
5
-
-
0036894554
-
Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: A prospective, randomized clinical pilot trial 2002 volvo award in clinical studies
-
DOI 10.1097/00007632-200212010-00005
-
Boden SD, Kang J, Sandhu H, Heller JG., Use of recombinant human bone morphogenetic protein 2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial [2002 Volvo Award in clinical studies]. Spine (Phila). 2002; 27: 2662-2673. (Pubitemid 35425320)
-
(2002)
Spine
, vol.27
, Issue.23
, pp. 2662-2673
-
-
Boden, S.D.1
Kang, J.2
Sandhu, H.3
Heller, J.G.4
-
6
-
-
51349159693
-
The use of bone morphogenetic protein in lumbar spine surgery
-
Rihn JA, Gates C, Glassman SD, Phillips FM, Schwender JD, Albert TJ., The use of bone morphogenetic protein in lumbar spine surgery. J Bone Joint Surg Am. 2008; 90: 2014-2025.
-
(2008)
J Bone Joint Surg Am.
, vol.90
, pp. 2014-2025
-
-
Rihn, J.A.1
Gates, C.2
Glassman, S.D.3
Phillips, F.M.4
Schwender, J.D.5
Albert, T.J.6
-
7
-
-
67649117871
-
Adverse effects of posterior lumbar interbody fusion using rhBMP-2
-
author reply 924
-
Smoljanovic T, Bojanic I, Delimar D., Adverse effects of posterior lumbar interbody fusion using rhBMP-2. Eur Spine J. 2009; 18: 920-923 author reply 924.
-
(2009)
Eur Spine J.
, vol.18
, pp. 920-923
-
-
Smoljanovic, T.1
Bojanic, I.2
Delimar, D.3
-
8
-
-
0032994043
-
Signal transduction by bone morphogenetic protein receptors: Functional roles of Smad proteins
-
DOI 10.1016/S8756-3282(99)00113-1, PII S8756328299001131
-
Miyazono K., Signal transduction by bone morphogenetic protein receptors: functional roles of Smad proteins. Bone. 1999; 25: 91-93. (Pubitemid 29322068)
-
(1999)
Bone
, vol.25
, Issue.1
, pp. 91-93
-
-
Miyazono, K.1
-
9
-
-
0034021776
-
Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
-
Gilboa L, Nohe A, Geissendorfer T, Sebald W, Henis YI, Knaus P., Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell. 2000; 11: 1023-1035. (Pubitemid 30159319)
-
(2000)
Molecular Biology of the Cell
, vol.11
, Issue.3
, pp. 1023-1035
-
-
Gilboa, L.1
Nohe, A.2
Geissendorfer, T.3
Sebald, W.4
Henis, Y.I.5
Knaus, P.6
-
11
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
-
Hayashi H, Abdollah S, Qiu Y, et al. The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell. 1997; 89: 1165-1173. (Pubitemid 127678749)
-
(1997)
Cell
, vol.89
, Issue.7
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.-Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone Jr., M.A.9
Wrana, J.L.10
Falb, D.11
-
12
-
-
0030765945
-
Smad6 inhibits signalling by the TGF-β superfamily
-
DOI 10.1038/39355
-
Imamura T, Takase M, Nishihara A, et al. Smad6 inhibits signalling by the TGF-beta superfamily. Nature. 1997; 389: 622-626. (Pubitemid 27446182)
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 622-626
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
Oeda, E.4
Hanai, J.-I.5
Kawabata, M.6
Miyazono, K.7
-
13
-
-
0031964859
-
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
-
Hata A, Lagna G, Massague J, Hemmati-Brivanlou A., Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev. 1998; 12: 186-197. (Pubitemid 28060449)
-
(1998)
Genes and Development
, vol.12
, Issue.2
, pp. 186-197
-
-
Hata, A.1
Lagna, G.2
Massague, J.3
Hemmati-Brivanlou, A.4
-
14
-
-
34547122921
-
Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors
-
DOI 10.1074/jbc.M702100200
-
Goto K, Kamiya Y, Imamura T, Miyazono K, Miyazawa K., Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors. J Biol Chem. 2007; 282: 20603-20611. (Pubitemid 47100044)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.28
, pp. 20603-20611
-
-
Goto, K.1
Kamiya, Y.2
Imamura, T.3
Miyazono, K.4
Miyazawa, K.5
-
15
-
-
37249015430
-
Multiplicity of BMP signaling in skeletal development
-
DOI 10.1196/annals.1402.053, Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling
-
Wu X, Shi W, Cao X., Multiplicity of BMP signaling in skeletal development. Ann N Y Acad Sci. 2007; 1116: 29-49. (Pubitemid 350274336)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1116
, pp. 29-49
-
-
Wu, X.1
Shi, W.2
Cao, X.3
-
16
-
-
58149216052
-
Signaling cross-talk between TGF-beta/BMP and other pathways
-
Guo X, Wang XF., Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res. 2009; 19: 71-88.
-
(2009)
Cell Res.
, vol.19
, pp. 71-88
-
-
Guo, X.1
Wang, X.F.2
-
17
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
DOI 10.1038/35065000
-
Chang L, Karin M., Mammalian MAP kinase signalling cascades. Nature. 2001; 410: 37-40. (Pubitemid 32225829)
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
18
-
-
0035046919
-
Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cells
-
DOI 10.1016/S8756-3282(01)00415-X, PII S875632820100415X
-
Gallea S, Lallemand F, Atfi A, et al. Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12cells. Bone. 2001; 28: 491-498. (Pubitemid 32410000)
-
(2001)
Bone
, vol.28
, Issue.5
, pp. 491-498
-
-
Gallea, S.1
Lallemand, F.2
Atfi, A.3
Rawadi, G.4
Ramez, V.5
Spinella-Jaegle, S.6
Kawai, S.7
Faucheu, C.8
Huet, L.9
Baron, R.10
Roman-Roman, S.11
-
19
-
-
0037005903
-
Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2
-
DOI 10.1016/S0014-5793(01)03236-7, PII S0014579301032367
-
Vinals F, Lopez-Rovira T, Rosa JL, Ventura F., Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2. FEBS Lett. 2002; 510: 99-104. (Pubitemid 34084891)
-
(2002)
FEBS Letters
, vol.510
, Issue.1-2
, pp. 99-104
-
-
Vials, F.1
Lopez-Rovira, T.2
Rosa, J.L.3
Ventura, F.4
-
20
-
-
24744462930
-
BMP-2 and insulin-like growth factor-I mediate osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways
-
DOI 10.1074/jbc.M503845200
-
Celil AB, Campbell PG., BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways. J Biol Chem. 2005; 280: 31353-31359. (Pubitemid 41291875)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.36
, pp. 31353-31359
-
-
Celil, A.B.1
Campbell, P.G.2
-
21
-
-
0242664611
-
Activation of p38 Mitogen-Activated Protein Kinase and c-Jun-NH2-Terminal Kinase by BMP-2 and Their Implication in the Stimulation of Osteoblastic Cell Differentiation
-
DOI 10.1359/jbmr.2003.18.11.2060
-
Guicheux J, Lemonnier J, Ghayor C, Suzuki A, Palmer G, Caverzasio J., Activation of p38 mitogen-activated protein kinase and c-Jun-NH2-terminal kinase by BMP-2 and their implication in the stimulation of osteoblastic cell differentiation. J Bone Miner Res. 2003; 18: 2060-2068. (Pubitemid 37377457)
-
(2003)
Journal of Bone and Mineral Research
, vol.18
, Issue.11
, pp. 2060-2068
-
-
Guicheux, J.1
Lemonnier, J.2
Ghayor, C.3
Suzuki, A.4
Palmer, G.5
Caverzasio, J.6
-
22
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ., Signal transduction by the JNK group of MAP kinases. Cell. 2000; 103: 239-252.
-
(2000)
Cell.
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
23
-
-
61849095684
-
JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation
-
Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T., JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation. J Bone Miner Res. 2009; 24: 398-410.
-
(2009)
J Bone Miner Res.
, vol.24
, pp. 398-410
-
-
Matsuguchi, T.1
Chiba, N.2
Bandow, K.3
Kakimoto, K.4
Masuda, A.5
Ohnishi, T.6
-
24
-
-
0345791533
-
Protein Kinase C-independent Activation of Protein Kinase D Is Involved in BMP-2-induced Activation of Stress Mitogen-activated Protein Kinases JNK and p38 and Osteoblastic Cell Differentiation
-
DOI 10.1074/jbc.M308665200
-
Lemonnier J, Ghayor C, Guicheux J, Caverzasio J., Protein kinase C-independent activation of protein kinase D is involved in BMP-2-induced activation of stress mitogen-activated protein kinases JNK and p38 and osteoblastic cell differentiation. J Biol Chem. 2004; 279: 259-264. (Pubitemid 38044823)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.1
, pp. 259-264
-
-
Lemonnier, J.1
Ghayor, C.2
Guicheux, J.3
Caverzasio, J.4
-
25
-
-
0032983542
-
Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
-
DOI 10.1359/jbmr.1999.14.6.893
-
Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT., Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res. 1999; 14: 893-903. (Pubitemid 29262883)
-
(1999)
Journal of Bone and Mineral Research
, vol.14
, Issue.6
, pp. 893-903
-
-
Wang, D.1
Christensen, K.2
Chawla, K.3
Xiao, G.4
Krebsbach, P.H.5
Franceschi, R.T.6
-
26
-
-
0029893684
-
Differential effects and glucocorticoid potentiation of bone morphogenetic protein action during rat osteoblast differentiation in vitro
-
DOI 10.1210/en.137.8.3401
-
Boden SD, McCuaig K, Hair G, et al. Differential effects and glucocorticoid potentiation of bone morphogenetic protein action during rat osteoblast differentiation in vitro. Endocrinology. 1996; 137: 3401-3407. (Pubitemid 26250191)
-
(1996)
Endocrinology
, vol.137
, Issue.8
, pp. 3401-3407
-
-
Boden, S.D.1
Mccuaig, K.2
Hair, G.3
Racine, M.4
Titus, L.5
Wozney, J.M.6
Nanes, M.S.7
-
27
-
-
71949124553
-
Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity
-
Okada M, Sangadala S, Liu Y, et al. Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity. Cell Biochem Funct. 2009; 27: 526-534.
-
(2009)
Cell Biochem Funct.
, vol.27
, pp. 526-534
-
-
Okada, M.1
Sangadala, S.2
Liu, Y.3
-
28
-
-
0036269755
-
2-terminal kinase
-
DOI 10.1128/MCB.22.13.4929-4942.2002
-
Lei K, Nimnual A, Zong WX, et al. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol. 2002; 22: 4929-4942. (Pubitemid 34620425)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.13
, pp. 4929-4942
-
-
Lei, K.1
Nimnual, A.2
Zong, W.-X.3
Kennedy, N.J.4
Flavell, R.A.5
Thompson, C.B.6
Bar-Sagi, D.7
Davis, R.J.8
-
29
-
-
34548278797
-
Effect on bone induction of using contrast media to reconstitute recombinant human bone morphogenetic protein-2 in an ectopic model in rats
-
DOI 10.3171/spi.2006.5.5.434
-
Zanella JM, Oliver C, Peckham SM, McKay B, Toth JM, Boden SD., Effect on bone induction of using contrast media to reconstitute recombinant human bone morphogenetic protein-2 in an ectopic model in rats. J Neurosurg Spine. 2006; 5: 434-439. (Pubitemid 47325354)
-
(2006)
Journal of Neurosurgery: Spine
, vol.5
, Issue.5
, pp. 434-439
-
-
Zanella, J.M.1
Oliver, C.2
Peckham, S.M.3
McKay, B.4
Toth, J.M.5
Boden, S.D.6
-
30
-
-
0036133374
-
Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells
-
Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, Franceschi RT., Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1cells. J Bone Miner Res. 2002; 17: 101-110. (Pubitemid 33151001)
-
(2002)
Journal of Bone and Mineral Research
, vol.17
, Issue.1
, pp. 101-110
-
-
Xiao, G.1
Gopalakrishnan, R.2
Jiang, D.3
Reith, E.4
Benson, M.D.5
Franceschi, R.T.6
-
31
-
-
16544387701
-
Induction of osteoblast differentiation indices by statins in MC3T3-E1cells
-
Maeda T, Matsunuma A, Kurahashi I, Yanagawa T, Yoshida H, Horiuchi N., Induction of osteoblast differentiation indices by statins in MC3T3-E1cells. J Cell Biochem. 2004; 92: 458-471.
-
(2004)
J Cell Biochem.
, vol.92
, pp. 458-471
-
-
Maeda, T.1
Matsunuma, A.2
Kurahashi, I.3
Yanagawa, T.4
Yoshida, H.5
Horiuchi, N.6
-
32
-
-
33748028794
-
Ras-MAPK signaling in osteogenic differentiation: Friend or foe?
-
DOI 10.1359/jbmr.060603
-
Schindeler A, Little DG., Ras-MAPK signaling in osteogenic differentiation: friend or foe ? J Bone Miner Res. 2006; 21: 1331-1338. (Pubitemid 44300039)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, Issue.9
, pp. 1331-1338
-
-
Schindeler, A.1
Little, D.G.2
-
33
-
-
24644476507
-
Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: Implications for carcinogenesis
-
DOI 10.1038/sj.onc.1208928, PII 1208928
-
Javelaud D, Mauviel A., Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis. Oncogene. 2005; 24: 5742-5750. (Pubitemid 43086134)
-
(2005)
Oncogene
, vol.24
, Issue.37
, pp. 5742-5750
-
-
Javelaud, D.1
Mauviel, A.2
-
34
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
-
DOI 10.1038/39348
-
Kretzschmar M, Doody J, Massague J., Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1. Nature. 1997; 389: 618-622. (Pubitemid 27446181)
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massague, J.3
-
35
-
-
46849092804
-
To (TGF)beta or not to (TGF)beta: Fine-tuning of Smad signaling via post-translational modifications
-
Wrighton KH, Feng XH., To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications. Cell Signal. 2008; 20: 1579-1591.
-
(2008)
Cell Signal.
, vol.20
, pp. 1579-1591
-
-
Wrighton, K.H.1
Feng, X.H.2
-
36
-
-
33846688094
-
Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
-
DOI 10.1016/j.molcel.2007.01.006, PII S109727650700010X
-
Sapkota G, Alarcon C, Spagnoli FM, Brivanlou AH, Massague J., Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol Cell. 2007; 25: 441-454. (Pubitemid 46199289)
-
(2007)
Molecular Cell
, vol.25
, Issue.3
, pp. 441-454
-
-
Sapkota, G.1
Alarcon, C.2
Spagnoli, F.M.3
Brivanlou, A.H.4
Massague, J.5
-
37
-
-
33845970267
-
Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-β pathways
-
DOI 10.1074/jbc.M610172200
-
Sapkota G, Knockaert M, Alarcon C, Montalvo E, Brivanlou AH, Massague J., Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways. J Biol Chem. 2006; 281: 40412-40419. (Pubitemid 46041844)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.52
, pp. 40412-40419
-
-
Sapkota, G.1
Knockaert, M.2
Alarco, C.3
Montalvo, E.4
Brivanlou, A.H.5
Massague, J.6
|